{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,6]],"date-time":"2026-09-06T00:29:16Z","timestamp":1788654556901,"version":"build-2803163510"},"reference-count":27,"publisher":"Elsevier BV","issue":"9","license":[{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","ejso.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Surgical Oncology"],"published-print":{"date-parts":[[2021,9]]},"DOI":"10.1016\/j.ejso.2021.04.007","type":"journal-article","created":{"date-parts":[[2021,4,17]],"date-time":"2021-04-17T22:15:50Z","timestamp":1618697750000},"page":"2454-2459","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"title":["Therapeutic neck dissection in head and neck melanoma patients: Comparing extent of surgery and clinical outcome in two cohorts"],"prefix":"10.1016","volume":"47","author":[{"given":"Danique M.S.","family":"Berger","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Danielle","family":"Verver","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vincent","family":"van der Noort","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8293-6002","authenticated-orcid":false,"given":"Dirk J.","family":"Gr\u00fcnhagen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cees","family":"Verhoef","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abrahim","family":"Al-Mamgani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charlotte L.","family":"Zuur","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander C.J.","family":"van Akkooi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alfons J.M.","family":"Balm","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"W. Martin C.","family":"Klop","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"4","key":"10.1016\/j.ejso.2021.04.007_bib1","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1016\/j.ijom.2011.12.027","article-title":"Lymphatic drainage patterns of head and neck cutaneous melanoma: does primary melanoma site correlate with anatomic distribution of pathologically involved lymph nodes?","volume":"41","author":"Suton","year":"2012","journal-title":"Int J Oral Maxillofac Surg"},{"issue":"1","key":"10.1016\/j.ejso.2021.04.007_bib2","first-page":"28","article-title":"The role of parotidectomy in the treatment of nodal metastases from cutaneous melanoma of the head and neck","volume":"16","author":"Vaglini","year":"1990","journal-title":"Eur J Surg Oncol"},{"issue":"5","key":"10.1016\/j.ejso.2021.04.007_bib3","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1016\/S0002-9610(99)80330-4","article-title":"Prediction of potential metastatic sites in cutaneous head and neck melanoma using lymphoscintigraphy","volume":"170","author":"O'Brien","year":"1995","journal-title":"Am J Surg"},{"issue":"4","key":"10.1016\/j.ejso.2021.04.007_bib4","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1002\/jso.20080","article-title":"Controversies in the management of metastatic melanoma to regional lymphatic basins","volume":"86","author":"Mack","year":"2004","journal-title":"J\u00a0Surg Oncol"},{"issue":"9","key":"10.1016\/j.ejso.2021.04.007_bib5","doi-asserted-by":"crossref","first-page":"785","DOI":"10.1002\/hed.1112","article-title":"Do nodal metastases from cutaneous melanoma of the head and neck follow a clinically predictable pattern?","volume":"23","author":"Pathak","year":"2001","journal-title":"Head Neck"},{"issue":"1","key":"10.1016\/j.ejso.2021.04.007_bib6","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1002\/bjs.1800810121","article-title":"Superficial parotidectomy in the treatment of cutaneous melanoma of the head and neck","volume":"81","author":"Barr","year":"1994","journal-title":"Br J Surg"},{"issue":"4","key":"10.1016\/j.ejso.2021.04.007_bib7","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1016\/0002-9610(91)90140-9","article-title":"Patterns of regional lymph node metastases from cutaneous melanomas of the head and neck","volume":"162","author":"Shah","year":"1991","journal-title":"Am J Surg"},{"issue":"7","key":"10.1016\/j.ejso.2021.04.007_bib8","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1016\/j.ejso.2013.02.022","article-title":"Is complete lymph node dissection after a positive sentinel lymph node biopsy for cutaneous melanoma always necessary? A meta-analysis","volume":"39","author":"Nagaraja","year":"2013","journal-title":"Eur J Surg Oncol"},{"issue":"11","key":"10.1016\/j.ejso.2021.04.007_bib9","doi-asserted-by":"crossref","first-page":"1014","DOI":"10.1001\/jamaoto.2014.2056","article-title":"Regional control of head and neck melanoma with selective neck dissection","volume":"140","author":"Geltzeiler","year":"2014","journal-title":"JAMA Otolaryngol Head Neck Surg"},{"issue":"5","key":"10.1016\/j.ejso.2021.04.007_bib10","doi-asserted-by":"crossref","first-page":"610","DOI":"10.1016\/j.amjoto.2014.06.011","article-title":"Managing regional metastasis in patients with cutaneous head and neck melanoma - is selective neck dissection appropriate?","volume":"35","author":"Supriya","year":"2014","journal-title":"Am J Otolaryngol"},{"issue":"3","key":"10.1016\/j.ejso.2021.04.007_bib11","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1002\/hed.2880170311","article-title":"Radical, modified, and selective neck dissection for cutaneous malignant melanoma","volume":"17","author":"O'Brien","year":"1995","journal-title":"Head Neck"},{"issue":"8","key":"10.1016\/j.ejso.2021.04.007_bib12","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1001\/archoto.2009.80","article-title":"Regional control of melanoma neck node metastasis after selective neck dissection with or without adjuvant radiotherapy","volume":"135","author":"Hamming-Vrieze","year":"2009","journal-title":"Arch Otolaryngol Head Neck Surg"},{"issue":"10","key":"10.1016\/j.ejso.2021.04.007_bib13","doi-asserted-by":"crossref","first-page":"1216","DOI":"10.1016\/j.ejso.2005.07.013","article-title":"Surgical technique - unwrapping the neck node levels around a sternocleidomastoid muscle bar: a systematic way of performing (modified) radical neck dissection","volume":"31","author":"Balm","year":"2005","journal-title":"Eur J Surg Oncol"},{"issue":"7","key":"10.1016\/j.ejso.2021.04.007_bib14","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1001\/archotol.128.7.751","article-title":"Neck dissection classification update","volume":"128","author":"Robbins","year":"2002","journal-title":"Arch Otolaryngol Head Neck Surg"},{"key":"10.1016\/j.ejso.2021.04.007_bib15","series-title":"AJCC cancer staging manual","year":"2017"},{"issue":"11","key":"10.1016\/j.ejso.2021.04.007_bib16","doi-asserted-by":"crossref","first-page":"2994","DOI":"10.1245\/s10434-009-0650-y","article-title":"Evaluation of lymphatic drainage patterns to the groin and implications for the extent of groin dissection in melanoma patients","volume":"16","author":"van der Ploeg","year":"2009","journal-title":"Ann Surg Oncol"},{"key":"10.1016\/j.ejso.2021.04.007_bib17","doi-asserted-by":"crossref","first-page":"S1172","DOI":"10.1245\/s10434-015-4602-4","article-title":"Risk factors for positive deep pelvic nodal involvement in patients with palpable groin melanoma metastases: can extent of surgery be minimized?","volume":"22Suppl3","author":"Oude Ophuis","year":"2015","journal-title":"Ann Surg Oncol"},{"issue":"12","key":"10.1016\/j.ejso.2021.04.007_bib18","doi-asserted-by":"crossref","first-page":"3300","DOI":"10.1245\/s10434-011-1741-0","article-title":"Therapeutic surgical management of palpable melanoma groin metastases: superficial or combined superficial and deep groin lymph node dissection","volume":"18","author":"van der Ploeg","year":"2011","journal-title":"Ann Surg Oncol"},{"issue":"1","key":"10.1016\/j.ejso.2021.04.007_bib19","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1002\/bjs.10644","article-title":"Optimal extent of completion lymphadenectomy for patients with melanoma and a positive sentinel node in the groin","volume":"105","author":"Verver","year":"2018","journal-title":"Br J Surg"},{"issue":"23","key":"10.1016\/j.ejso.2021.04.007_bib20","doi-asserted-by":"crossref","first-page":"2211","DOI":"10.1056\/NEJMoa1613210","article-title":"Completion dissection or observation for sentinel-node metastasis in melanoma","volume":"376","author":"Faries","year":"2017","journal-title":"N\u00a0Engl J Med"},{"issue":"7","key":"10.1016\/j.ejso.2021.04.007_bib21","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1056\/NEJMoa1310460","article-title":"Final trial report of sentinel-node biopsy versus nodal observation in melanoma","volume":"370","author":"Morton","year":"2014","journal-title":"N\u00a0Engl J Med"},{"issue":"19","key":"10.1016\/j.ejso.2021.04.007_bib22","doi-asserted-by":"crossref","first-page":"1845","DOI":"10.1056\/NEJMoa1611299","article-title":"Prolonged survival in stage III melanoma with ipilimumab adjuvant therapy","volume":"375","author":"Eggermont","year":"2016","journal-title":"N\u00a0Engl J Med"},{"issue":"19","key":"10.1016\/j.ejso.2021.04.007_bib23","doi-asserted-by":"crossref","first-page":"1824","DOI":"10.1056\/NEJMoa1709030","article-title":"Adjuvant nivolumab versus ipilimumab in resected stage III or IV melanoma","volume":"377","author":"Weber","year":"2017","journal-title":"N\u00a0Engl J Med"},{"issue":"19","key":"10.1016\/j.ejso.2021.04.007_bib24","doi-asserted-by":"crossref","first-page":"1789","DOI":"10.1056\/NEJMoa1802357","article-title":"Adjuvant pembrolizumab versus placebo in resected stage III melanoma","volume":"378","author":"Eggermont","year":"2018","journal-title":"N\u00a0Engl J Med"},{"issue":"7","key":"10.1016\/j.ejso.2021.04.007_bib25","doi-asserted-by":"crossref","first-page":"948","DOI":"10.1016\/S1470-2045(19)30151-2","article-title":"Identification of the optimal combination dosing schedule of neoadjuvant ipilimumab plus nivolumab in macroscopic stage III melanoma (OpACIN-neo): a multicentre, phase 2, randomised, controlled trial","volume":"20","author":"Rozeman","year":"2019","journal-title":"Lancet Oncol"},{"issue":"2","key":"10.1016\/j.ejso.2021.04.007_bib26","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1038\/s41591-020-01211-7","article-title":"Survival and biomarker analyses from the OpACIN-neo and OpACIN neoadjuvant immunotherapy trials in stage III melanoma","volume":"27","author":"Rozeman","year":"2021","journal-title":"Nat Med"},{"issue":"5","key":"10.1016\/j.ejso.2021.04.007_bib27","doi-asserted-by":"crossref","first-page":"486","DOI":"10.1001\/archotol.133.5.486","article-title":"Superselective neck dissection after chemoradiation: feasibility based on clinical and pathologic comparisons","volume":"133","author":"Robbins","year":"2007","journal-title":"Arch Otolaryngol Head Neck Surg"}],"container-title":["European Journal of Surgical Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0748798321004121?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0748798321004121?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T01:40:06Z","timestamp":1760060406000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0748798321004121"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,9]]},"references-count":27,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2021,9]]}},"alternative-id":["S0748798321004121"],"URL":"https:\/\/doi.org\/10.1016\/j.ejso.2021.04.007","relation":{},"ISSN":["0748-7983"],"issn-type":[{"value":"0748-7983","type":"print"}],"subject":[],"published":{"date-parts":[[2021,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Therapeutic neck dissection in head and neck melanoma patients: Comparing extent of surgery and clinical outcome in two cohorts","name":"articletitle","label":"Article Title"},{"value":"European Journal of Surgical Oncology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ejso.2021.04.007","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Elsevier Ltd, BASO ~ The Association for Cancer Surgery, and the European Society of Surgical Oncology. All rights reserved.","name":"copyright","label":"Copyright"}]}}