{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,30]],"date-time":"2026-08-30T02:12:38Z","timestamp":1788055958772,"version":"build-2784847793"},"reference-count":79,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T00:00:00Z","timestamp":1648771200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T00:00:00Z","timestamp":1648771200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100003196","name":"Ministero della Salute","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003196","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004710","name":"Fondazione Umberto Veronesi","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004710","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","ejso.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Surgical Oncology"],"published-print":{"date-parts":[[2022,4]]},"DOI":"10.1016\/j.ejso.2021.10.030","type":"journal-article","created":{"date-parts":[[2021,11,9]],"date-time":"2021-11-09T03:17:07Z","timestamp":1636427827000},"page":"736-741","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":34,"title":["Advances and controversies in management of breast ductal carcinoma in situ (DCIS)"],"prefix":"10.1016","volume":"48","author":[{"given":"Gabriel","family":"Farante","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8004-1907","authenticated-orcid":false,"given":"Antonio","family":"Toesca","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesca","family":"Magnoni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Germana","family":"Lissidini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9","family":"Vila","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8306-0839","authenticated-orcid":false,"given":"Mauro","family":"Mastropasqua","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giuseppe","family":"Viale","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silvia","family":"Penco","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3437-8939","authenticated-orcid":false,"given":"Enrico","family":"Cassano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2162-4002","authenticated-orcid":false,"given":"Matteo","family":"Lazzeroni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3589-2128","authenticated-orcid":false,"given":"Bernardo","family":"Bonanni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria Cristina","family":"Leonardi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francisco","family":"Ripoll-Orts","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giuseppe","family":"Curigliano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roberto","family":"Orecchia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Viviana","family":"Galimberti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paolo","family":"Veronesi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ejso.2021.10.030_bib1","doi-asserted-by":"crossref","first-page":"2965","DOI":"10.1245\/s10434-018-6580-9","article-title":"American society of breast surgeons' practice patterns after publication of the SSO-ASTRO-ASCO DCIS consensus guideline on margins for breast-conserving surgery with whole-breast irradiation","volume":"25","author":"DeSnyder","year":"2018","journal-title":"Ann Surg Oncol"},{"key":"10.1016\/j.ejso.2021.10.030_bib2","doi-asserted-by":"crossref","first-page":"829","DOI":"10.1016\/j.breast.2014.08.016","article-title":"Breast conservative surgery for well-differentiated ductal intraepithelial neoplasia: risk factors for ipsilateral breast tumor recurrence","volume":"23","author":"Toesca","year":"2014","journal-title":"Breast"},{"key":"10.1016\/j.ejso.2021.10.030_bib3","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1148\/radiol.12111461","article-title":"Comparison of digital screening mammography and screen-film mammography in the early detection of clinically relevant cancers: a multicenter study","volume":"265","author":"Bluekens","year":"2012","journal-title":"Radiology"},{"issue":"7","key":"10.1016\/j.ejso.2021.10.030_bib4","doi-asserted-by":"crossref","first-page":"888","DOI":"10.1001\/jamaoncol.2015.2510","article-title":"Breast cancer mortality after a diagnosis of ductal carcinoma in situ","volume":"1","author":"Narod","year":"2015","journal-title":"JAMA Oncol"},{"key":"10.1016\/j.ejso.2021.10.030_bib5","doi-asserted-by":"crossref","first-page":"3762","DOI":"10.1200\/JCO.2009.26.8847","article-title":"Nomogram for predicting the risk of local recurrence after breast-conserving surgery for ductal carcinoma in situ","volume":"28","author":"Rudloff","year":"2010","journal-title":"J\u00a0Clin Oncol"},{"key":"10.1016\/j.ejso.2021.10.030_bib6","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1097\/PPO.0000000000000025","article-title":"Local relapse after breast-conserving therapy for ductal carcinoma in situ: a European single-center experience and external validation of the Memorial Sloan-Kettering Cancer Center DCIS nomogram","volume":"20","author":"Sweldens","year":"2014","journal-title":"Cancer J"},{"key":"10.1016\/j.ejso.2021.10.030_bib7","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1016\/j.crad.2019.10.009","article-title":"Non-mass versus mass-like ultrasound patterns in ductal carcinoma in situ: is there an association with high-risk histology?","volume":"75","author":"Gunawardena","year":"2020","journal-title":"Clin Radiol"},{"key":"10.1016\/j.ejso.2021.10.030_bib8","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1038\/s41416-019-0478-6","article-title":"PRECISION team. Ductal carcinoma in situ: to treat or not to treat, that is the question","volume":"121","author":"Van Seijen","year":"2019","journal-title":"Br J Cancer"},{"key":"10.1016\/j.ejso.2021.10.030_bib9","doi-asserted-by":"crossref","first-page":"2499","DOI":"10.1001\/jama.2014.6095","article-title":"Breast cancer screening using tomosynthesis in combination with digital mammography","volume":"311","author":"Friedewald","year":"2014","journal-title":"J\u00a0Am Med Assoc"},{"key":"10.1016\/j.ejso.2021.10.030_bib10","doi-asserted-by":"crossref","first-page":"1687","DOI":"10.7863\/jum.2010.29.12.1687","article-title":"Sonographic findings of high-grade and non-high-grade ductal carcinoma in situ of the breast","volume":"29","author":"Park","year":"2010","journal-title":"J\u00a0Ultrasound Med"},{"key":"10.1016\/j.ejso.2021.10.030_bib11","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1111\/j.1075-122X.2005.00121.x","article-title":"Determination of the presence and extent of pure ductal carcinoma in situ by mammography and magnetic resonance imaging","volume":"11","author":"Menell","year":"2005","journal-title":"Breast J"},{"key":"10.1016\/j.ejso.2021.10.030_bib12","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1016\/S0140-6736(07)61232-X","article-title":"MRI for diagnosis of pure ductal carcinoma in situ: a prospective observational study","volume":"370","author":"Kuhl","year":"2007","journal-title":"Lancet"},{"key":"10.1016\/j.ejso.2021.10.030_bib13","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1111\/tbj.12948","article-title":"MR imaging appearance of noncalcified and calcified DCIS","volume":"24","author":"Scott-Moncrieff","year":"2018","journal-title":"Breast J"},{"key":"10.1016\/j.ejso.2021.10.030_bib14","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1016\/j.ejrad.2014.12.029","article-title":"Accuracy of 3 T versus 1.5 T breast MRI for pre-operative assessment of extent of disease in newly diagnosed DCIS","volume":"84","author":"Rahbar","year":"2015","journal-title":"Eur J Radiol"},{"key":"10.1016\/j.ejso.2021.10.030_bib15","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/j.clinimag.2015.07.026","article-title":"Can MRI biomarkers at 3 T identify low-risk ductal carcinoma in situ?","volume":"40","author":"Rahbar","year":"2016","journal-title":"Clin Imag"},{"key":"10.1016\/j.ejso.2021.10.030_bib16","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1016\/j.ctrv.2010.03.007","article-title":"Current perspectives of treatment of ductal carcinoma in situ","volume":"36","author":"Estevez","year":"2010","journal-title":"Cancer Treat Rev"},{"key":"10.1016\/j.ejso.2021.10.030_bib17","doi-asserted-by":"crossref","first-page":"780","DOI":"10.1016\/j.ejrad.2015.12.027","article-title":"Preoperative clinicopathologic factors and breast magnetic resonance imaging features can predict ductal carcinoma in situ with invasive components","volume":"85","author":"Lee","year":"2016","journal-title":"Eur J Radiol"},{"key":"10.1016\/j.ejso.2021.10.030_bib18","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1016\/j.breast.2012.06.009","article-title":"Predictors of invasive breast cancer and lymph node involvement in ductal carcinoma in situ initially diagnosed by vacuum-assisted breast biopsy: experience of 733 cases","volume":"21","author":"Trentin","year":"2012","journal-title":"Breast"},{"key":"10.1016\/j.ejso.2021.10.030_bib19","doi-asserted-by":"crossref","DOI":"10.1016\/j.ejso.2016.07.011","article-title":"Clinical and pathological assessment of high-risk ductal and lobular breast lesions: what surgeons must know","volume":"43","author":"Mastropasqua","year":"2017","journal-title":"Eur J Surg Oncol"},{"key":"10.1016\/j.ejso.2021.10.030_bib20","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1097\/PAS.0b013e318161d1a5","article-title":"Morphologic and molecular evolutionary pathways of low nuclear grade invasive breast cancers and their putative precursor lesions: further evidence to support the concept of low nuclear grade breast neoplasia family","volume":"32","author":"Abdel-Fatah","year":"2008","journal-title":"Am J Surg Pathol"},{"key":"10.1016\/j.ejso.2021.10.030_bib21","doi-asserted-by":"crossref","first-page":"734","DOI":"10.1097\/01.pas.0000157295.93914.3b","article-title":"Columnar cell lesions of the breast: the missing link in breast cancer progression? A morphological and molecular analysis","volume":"29","author":"Simpson","year":"2005","journal-title":"Am J Surg Pathol"},{"key":"10.1016\/j.ejso.2021.10.030_bib22","doi-asserted-by":"crossref","first-page":"13","DOI":"10.5858\/133.1.13","article-title":"College of American Pathologists protocol for the reporting of ductal carcinoma in situ","volume":"133","author":"Lester","year":"2009","journal-title":"Arch Pathol Lab Med"},{"key":"10.1016\/j.ejso.2021.10.030_bib23","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1002\/cncr.29775","article-title":"Breast cancer risk by extent and type of atypical hyperplasia: an update from the nurses' Health studies","volume":"122","author":"Collins","year":"2016","journal-title":"Cancer"},{"key":"10.1016\/j.ejso.2021.10.030_bib24","doi-asserted-by":"crossref","first-page":"1227","DOI":"10.1056\/NEJMoa020989","article-title":"Twenty-year follow-up of a randomized study comparing breast-conserving surgery with radical mastectomy for early breast cancer","volume":"347","author":"Veronesi","year":"2002","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.ejso.2021.10.030_bib25","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1146\/annurev-med-050715-104920","article-title":"Controversies in the treatment of ductal carcinoma in situ","volume":"68","author":"Barrio","year":"2017","journal-title":"Annu Rev Med"},{"key":"10.1016\/j.ejso.2021.10.030_bib26","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1007\/s10549-010-1124-4","article-title":"The management of ductal intraepithelial neoplasia (DIN): open controversies and guidelines of the Istituto Europeo di Oncologia (IEO), Milan, Italy","volume":"128","author":"Farante","year":"2011","journal-title":"Breast Cancer Res Treat"},{"key":"10.1016\/j.ejso.2021.10.030_bib27","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1097\/SLA.0000000000001454","article-title":"Relationship between margin width and recurrence of ductal carcinoma in situ: analysis of 2996 women treated with breast-conserving surgery for 30 years","volume":"262","author":"Van Zee","year":"2015","journal-title":"Ann Surg"},{"key":"10.1016\/j.ejso.2021.10.030_bib28","doi-asserted-by":"crossref","first-page":"1551","DOI":"10.1001\/jama.2009.1450","article-title":"Surgeon recommendations and receipt of mastectomy for treatment of breast cancer","volume":"302","author":"Morrow","year":"2009","journal-title":"J\u00a0Am Med Assoc"},{"key":"10.1016\/j.ejso.2021.10.030_bib29","doi-asserted-by":"crossref","first-page":"3801","DOI":"10.1245\/s10434-016-5449-z","article-title":"Society of surgical oncology-American society for radiation oncology-American society of clinical oncology consensus guideline on margins for breast-conserving surgery with whole-breast irradiation in ductal carcinoma in situ","volume":"23","author":"Morrow","year":"2016","journal-title":"Ann Surg Oncol"},{"issue":"14","key":"10.1016\/j.ejso.2021.10.030_bib30","first-page":"2653","article-title":"DCIS margins and breast conservation: MD Anderson cancer center multidisciplinary practice guidelines and outcomes","volume":"8","author":"Kuerer","year":"2017","journal-title":"J\u00a0Cancer"},{"key":"10.1016\/j.ejso.2021.10.030_bib31","series-title":"National comprehensive cancer network clinical guidelines version 3. Invasive breast cancer","year":"2019"},{"issue":"2","key":"10.1016\/j.ejso.2021.10.030_bib32","first-page":"145","article-title":"Radioguided Occult Lesions Localization (ROLL) and surgical biopsy in breast cancer. Technical aspects","volume":"46","author":"De Cicco","year":"2002","journal-title":"Q\u00a0J Nucl Med"},{"issue":"7","key":"10.1016\/j.ejso.2021.10.030_bib33","doi-asserted-by":"crossref","first-page":"957","DOI":"10.1016\/j.ejso.2018.04.015","article-title":"Oncoplastic breast surgery for the management of ductal carcinoma in situ (DCIS): is it oncologically safe? A retrospective cohort analysis","volume":"44","author":"De Lorenzi","year":"2018","journal-title":"Eur J Surg Oncol"},{"issue":"3","key":"10.1016\/j.ejso.2021.10.030_bib34","doi-asserted-by":"crossref","first-page":"284","DOI":"10.5301\/tj.5000500","article-title":"Surgical resection margins after breast-conserving surgery: senonetwork recommendations","volume":"102","author":"Galimberti","year":"2016","journal-title":"Tumori Journal"},{"issue":"1","key":"10.1016\/j.ejso.2021.10.030_bib35","doi-asserted-by":"crossref","first-page":"S82","DOI":"10.1016\/j.breast.2017.06.034","article-title":"Nipple-sparing and skin-sparing mastectomy: review of aims, oncological safety and contraindications","volume":"34","author":"Galimberti","year":"2017","journal-title":"Breast"},{"issue":"6","key":"10.1016\/j.ejso.2021.10.030_bib36","doi-asserted-by":"crossref","first-page":"1008","DOI":"10.1093\/annonc\/mdn732","article-title":"Unavoidable mastectomy for ipsilateral breast tumour recurrence after conservative surgery: patient outcome","volume":"20","author":"Botteri","year":"2009","journal-title":"Ann Oncol"},{"issue":"4","key":"10.1016\/j.ejso.2021.10.030_bib37","doi-asserted-by":"crossref","first-page":"632","DOI":"10.1097\/SLA.0b013e3181d35bf8","article-title":"Comparison of skin-sparing mastectomy versus non-skin-sparing mastectomy for breast cancer: a meta-analysis of observational studies","volume":"251","author":"Lanitis","year":"2010","journal-title":"Ann Surg"},{"issue":"13","key":"10.1016\/j.ejso.2021.10.030_bib38","doi-asserted-by":"crossref","first-page":"3849","DOI":"10.1245\/s10434-018-6759-0","article-title":"Oncological outcomes of nipple-sparing mastectomy: a single-center experience of 1989 patients","volume":"25","author":"Galimberti","year":"2018","journal-title":"Ann Surg Oncol"},{"issue":"12","key":"10.1016\/j.ejso.2021.10.030_bib39","doi-asserted-by":"crossref","first-page":"1751","DOI":"10.1016\/j.bjps.2018.07.022","article-title":"Nipple-sparing mastectomy with different approaches: surgical incisions, complications, and cosmetic results. Preliminary results of 100 consecutive patients at a single center","volume":"71","author":"Corso","year":"2018","journal-title":"J\u00a0Plast Reconstr Aesthetic Surg"},{"issue":"10","key":"10.1016\/j.ejso.2021.10.030_bib40","doi-asserted-by":"crossref","first-page":"3046","DOI":"10.1245\/s10434-019-07590-7","article-title":"Update on the feasibility and progress on robotic breast surgery","volume":"26","author":"Toesca","year":"2019","journal-title":"Ann Surg Oncol"},{"issue":"2","key":"10.1016\/j.ejso.2021.10.030_bib41","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1097\/SLA.0b013e31815b446b","article-title":"Sentinel node biopsy is not a standard procedure in ductal carcinoma in situ of the breast: the experience of the European institute of oncology on 854 patients in 10 years","volume":"247","author":"Intra","year":"2008","journal-title":"Ann Surg"},{"issue":"3","key":"10.1016\/j.ejso.2021.10.030_bib42","doi-asserted-by":"crossref","first-page":"476","DOI":"10.1016\/j.ejca.2009.12.004","article-title":"No more axillary dissection in patients with ductal intraepithelial neoplasia (DIN)","volume":"46","author":"Farante","year":"2010","journal-title":"Eur J Cancer"},{"key":"10.1016\/j.ejso.2021.10.030_bib43","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1002\/bjs.11377","article-title":"Multicentre study of the risk of invasive cancer and use of sentinel node biopsy in women with a preoperative diagnosis of ductal carcinoma in situ","volume":"107","author":"Munck","year":"2020","journal-title":"Br J Surg"},{"key":"10.1016\/j.ejso.2021.10.030_bib44","doi-asserted-by":"crossref","first-page":"478","DOI":"10.1093\/jnci\/djr027","article-title":"Long-term outcomes of invasive ipsilateral breast tumor recurrences after lumpectomy in NSABP B-17 and B-24 randomized clinical trials for DCIS","volume":"103","author":"Wapnir","year":"2011","journal-title":"J\u00a0Natl Cancer Inst"},{"key":"10.1016\/j.ejso.2021.10.030_bib45","doi-asserted-by":"crossref","first-page":"400","DOI":"10.1016\/S0093-7754(01)90133-2","article-title":"Prevention of invasive breast cancer in women with ductal carcinoma in situ: an update of the National Surgical Adjuvant Breast and Bowel Project experience","volume":"28","author":"Fisher","year":"2001","journal-title":"Semin Oncol"},{"key":"10.1016\/j.ejso.2021.10.030_bib46","doi-asserted-by":"crossref","first-page":"4054","DOI":"10.1200\/JCO.2013.49.5077","article-title":"Breast conserving treatment with or without radiotherapy in ductal carcinoma in situ: 15-year recurrence rates and outcome after a recurrence, from the EORTC 10853 randomized phase III trial","volume":"31","author":"Donker","year":"2013","journal-title":"J\u00a0Clin Oncol"},{"key":"10.1016\/j.ejso.2021.10.030_bib47","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/S1470-2045(10)70266-7","article-title":"Effect of tamoxifen and radiotherapy in women with locally excised ductal carcinoma in situ: long-term results from the UK\/ANZ DCIS trial","volume":"12","author":"Cuzick","year":"2011","journal-title":"Lancet Oncol"},{"key":"10.1016\/j.ejso.2021.10.030_bib48","doi-asserted-by":"crossref","first-page":"3613","DOI":"10.1200\/JCO.2014.56.2595","article-title":"Effect of radiotherapy after breast-conserving surgery for ductal carcinoma in situ: 20 years follow-up in the randomized SweDCIS trial","volume":"32","author":"Warnberg","year":"2014","journal-title":"J\u00a0Clin Oncol"},{"issue":"7","key":"10.1016\/j.ejso.2021.10.030_bib49","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1200\/JCO.2014.57.9029","article-title":"Rtog 9804: a prospective randomized trial for good-risk ductal carcinoma in situ comparing radiotherapy with observation","volume":"33","author":"McCormick","year":"2015","journal-title":"J\u00a0Clin Oncol"},{"key":"10.1016\/j.ejso.2021.10.030_bib50","first-page":"162","article-title":"Overview of the randomized trials of radiotherapy in ductal carcinoma in situ of the breast","volume":"41","author":"Correa","year":"2010","journal-title":"J\u00a0Natl Cancer Inst Monogr"},{"issue":"11","key":"10.1016\/j.ejso.2021.10.030_bib51","first-page":"CD000563","article-title":"Post-operative radiotherapy for ductal carcinoma in situ of the breast","author":"Goodwin","year":"2013","journal-title":"Cochrane Database Syst Rev"},{"issue":"8","key":"10.1016\/j.ejso.2021.10.030_bib52","doi-asserted-by":"crossref","first-page":"1593","DOI":"10.1038\/bjc.2013.147","article-title":"Tailoring treatment for ductal intraepithelial neoplasia of the breast according to Ki-67 and molecular phenotype","volume":"108","author":"Lazzeroni","year":"2013","journal-title":"Br J Cancer"},{"issue":"4","key":"10.1016\/j.ejso.2021.10.030_bib53","doi-asserted-by":"crossref","first-page":"682","DOI":"10.1093\/annonc\/mdv013","article-title":"Risk of subsequent in situ and invasive breast cancer in human epidermal growth factor receptor 2-positive ductal carcinoma in situ","volume":"26","author":"Curigliano","year":"2015","journal-title":"Ann Oncol"},{"issue":"8","key":"10.1016\/j.ejso.2021.10.030_bib54","doi-asserted-by":"crossref","first-page":"935","DOI":"10.1002\/jso.23933","article-title":"The impact of genomic testing on the recommendation for radiation therapy in patients with ductal carcinoma in situ: a prospective clinical utility assessment of the 12-gene DCIS score\u2122 result","volume":"111","author":"Alvarado","year":"2015","journal-title":"J\u00a0Surg Oncol"},{"issue":"2","key":"10.1016\/j.ejso.2021.10.030_bib55","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/j.prro.2016.09.007","article-title":"Accelerated partial breast irradiation: executive summary for the update of an ASTRO evidence-based consensus statement","volume":"7","author":"Correa","year":"2016","journal-title":"Pract Radiat Oncol"},{"issue":"1","key":"10.1016\/j.ejso.2021.10.030_bib56","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1245\/s10434-010-1192-z","article-title":"Update on DCIS outcomes from the American Society of Breast Surgeons accelerated partial breast irradiation registry trial","volume":"18","author":"Jeruss","year":"2011","journal-title":"Ann Surg Oncol"},{"issue":"10215","key":"10.1016\/j.ejso.2021.10.030_bib57","doi-asserted-by":"crossref","first-page":"2155","DOI":"10.1016\/S0140-6736(19)32514-0","article-title":"Long-term primary results of accelerated partial breast irradiation after breast-conserving surgery for early-stage breast cancer: a randomised, phase 3, equivalence trial","volume":"394","author":"Vicini","year":"2019","journal-title":"Lancet"},{"issue":"1","key":"10.1016\/j.ejso.2021.10.030_bib58","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/j.ijrobp.2010.08.034","article-title":"Outcomes in women treated with MammoSite brachytherapy or whole breast irradiation stratified by ASTRO accelerated partial breast irradiation consensus statement groups","volume":"82","author":"Zauls","year":"2012","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ejso.2021.10.030_bib59","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1016\/j.radonc.2018.12.030","article-title":"Ductal carcinoma in situ and intraoperative partial breast irradiation: who are the best candidates? Long-term outcome of a single institution series","volume":"133","author":"Leonardi","year":"2019","journal-title":"Radiother Oncol"},{"issue":"10015","key":"10.1016\/j.ejso.2021.10.030_bib60","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1016\/S0140-6736(15)00471-7","volume":"387","author":"Strnad","year":"2016","journal-title":"Lancet"},{"issue":"10215","key":"10.1016\/j.ejso.2021.10.030_bib61","doi-asserted-by":"crossref","first-page":"2165","DOI":"10.1016\/S0140-6736(19)32515-2","article-title":"External beam accelerated partial breast irradiation versus whole breast irradiation after breast conserving surgery in women with ductal carcinoma in situ and node-negative breast cancer (RAPID): a randomised controlled trial","volume":"394","author":"Whelan","year":"2019","journal-title":"Lancet"},{"issue":"11","key":"10.1016\/j.ejso.2021.10.030_bib62","doi-asserted-by":"crossref","first-page":"3487","DOI":"10.1245\/s10434-016-5268-2","article-title":"Do LORIS trial eligibility criteria identify a ductal carcinoma in situ patient population at low risk of upgrade to invasive carcinoma?","volume":"23","author":"Pilewskie","year":"2016","journal-title":"Ann Surg Oncol"},{"issue":"12","key":"10.1016\/j.ejso.2021.10.030_bib63","doi-asserted-by":"crossref","first-page":"1497","DOI":"10.1016\/j.ejca.2015.05.008","article-title":"Feasibility of a prospective, randomised, open-label, international multicentre, phase III, non-inferiority trial to assess the safety of active surveillance for low risk ductal carcinoma in situ - the LORD study","volume":"51","author":"Elshof","year":"2015","journal-title":"Eur J Cancer"},{"issue":"5","key":"10.1016\/j.ejso.2021.10.030_bib64","doi-asserted-by":"crossref","first-page":"1017","DOI":"10.1016\/j.ijrobp.2014.07.026","article-title":"Long-term outcomes of hypofractionation versus conventional radiation therapy after breast-conserving surgery for ductal carcinoma in situ of the breast","volume":"90","author":"Lalani","year":"2014","journal-title":"Int J Radiat Oncol Biol Phys"},{"issue":"1","key":"10.1016\/j.ejso.2021.10.030_bib65","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1016\/j.radonc.2015.01.001","article-title":"The role of boost and hypofractionation as adjuvant radiotherapy in patients with DCIS: a meta-analysis of observational studies","volume":"114","author":"Nilsson","year":"2015","journal-title":"Radiother Oncol"},{"issue":"4","key":"10.1016\/j.ejso.2021.10.030_bib66","doi-asserted-by":"crossref","first-page":"987","DOI":"10.1016\/j.ijrobp.2009.02.031","article-title":"Accelerated partial breast irradiation consensus statement from the American Society for Radiation Oncology (ASTRO)","volume":"74","author":"Smith","year":"2009","journal-title":"Int J Radiat Oncol Biol Phys"},{"issue":"8","key":"10.1016\/j.ejso.2021.10.030_bib67","doi-asserted-by":"crossref","first-page":"652","DOI":"10.1016\/S1470-2045(06)70765-3","article-title":"Boost radiotherapy in young women with ductal carcinoma in situ: a multicentre, retrospective study of the Rare Cancer Network","volume":"7","author":"Omlin","year":"2006","journal-title":"Lancet Oncol"},{"issue":"10","key":"10.1016\/j.ejso.2021.10.030_bib68","doi-asserted-by":"crossref","first-page":"1541","DOI":"10.1093\/annonc\/mdz235","article-title":"Estimating the benefits of therapy for early-stage breast cancer: the St. Gallen International Consensus Guidelines for the primary therapy of early breast cancer 2019","volume":"30","author":"Burstein","year":"2019","journal-title":"Ann Oncol"},{"key":"10.1016\/j.ejso.2021.10.030_bib69","doi-asserted-by":"crossref","first-page":"1993","DOI":"10.1016\/S0140-6736(99)05036-9","article-title":"Tamoxifen in treatment of intraductal breast cancer: national Surgical Adjuvant Breast and Bowel Project B-24 randomised controlled trial","volume":"353","author":"Fisher","year":"1999","journal-title":"Lancet"},{"key":"10.1016\/j.ejso.2021.10.030_bib70","doi-asserted-by":"crossref","first-page":"849","DOI":"10.1016\/S0140-6736(15)01168-X","article-title":"Anastrozole versus tamoxifen in postmenopausal women with ductal carcinoma in situ undergoing lumpectomy plus radiotherapy (NSABP B-35): a randomised, double-blind, phase 3 clinical trial","volume":"387","author":"Margolese","year":"2016","journal-title":"Lancet"},{"key":"10.1016\/j.ejso.2021.10.030_bib71","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.ctrv.2017.01.010","article-title":"Adjuvant therapy in patients with ductal carcinoma in situ of the breast: the Pandora's box","volume":"55","author":"Lazzeroni","year":"2017","journal-title":"Cancer Treat Rev"},{"key":"10.1016\/j.ejso.2021.10.030_bib72","doi-asserted-by":"crossref","first-page":"3152","DOI":"10.1200\/JCO.19.01472","article-title":"Use of endocrine therapy for breast cancer risk reduction: ASCO clinical practice guideline update","volume":"37","author":"Visvanathan","year":"2019","journal-title":"J\u00a0Clin Oncol"},{"key":"10.1016\/j.ejso.2021.10.030_bib73","doi-asserted-by":"crossref","first-page":"1629","DOI":"10.1200\/JCO.18.01779","article-title":"Randomized placebo controlled trial of low-dose tamoxifen to prevent local and contralateral recurrence in breast intraepithelial neoplasia","volume":"37","author":"DeCensi","year":"2019","journal-title":"J\u00a0Clin Oncol"},{"issue":"6","key":"10.1016\/j.ejso.2021.10.030_bib74","doi-asserted-by":"crossref","first-page":"1065","DOI":"10.1038\/s41379-020-0452-0","article-title":"Prognostic and predictive value of cell cycle progression (CCP) score in ductal carcinoma in situ of the breast","volume":"33","author":"Lazzeroni","year":"2020","journal-title":"Mod Pathol"},{"key":"10.1016\/j.ejso.2021.10.030_bib75","series-title":"The international collaboration of active surveillance trials for low-risk DCIS (LORIS, LORD, COMET, LORETTA)","author":"Kanbayashi","year":"2019"},{"issue":"3","key":"10.1016\/j.ejso.2021.10.030_bib76","doi-asserted-by":"crossref","DOI":"10.1136\/bmjopen-2018-026797","article-title":"The COMET (Comparison of Operative versus Monitoring and Endocrine Therapy) trial: a phase III randomised controlled clinical trial for low-risk ductal carcinoma in situ (DCIS)","volume":"9","author":"Hwang","year":"2019","journal-title":"BMJ Open"},{"issue":"12","key":"10.1016\/j.ejso.2021.10.030_bib77","doi-asserted-by":"crossref","first-page":"1284","DOI":"10.1200\/JCO.19.00510","article-title":"Phase II single-arm study of preoperative letrozole for estrogen receptor\u2013positive postmenopausal ductal carcinoma in situ: CALGB 40903 (alliance)","volume":"38","author":"Hwang","year":"2020","journal-title":"J\u00a0Clin Oncol"},{"issue":"12","key":"10.1016\/j.ejso.2021.10.030_bib78","doi-asserted-by":"crossref","first-page":"1252","DOI":"10.1200\/JCO.20.00124","article-title":"De-escalating treatment of low-risk breast ductal carcinoma in situ","volume":"38","author":"Lazzeroni","year":"2020","journal-title":"J\u00a0Clin Oncol"},{"issue":"11","key":"10.1016\/j.ejso.2021.10.030_bib79","doi-asserted-by":"crossref","first-page":"1007","DOI":"10.1001\/jamasurg.2017.2181","article-title":"Factors associated with underestimation of invasive cancer in patients with ductal carcinoma in situ: precautions for active surveillance","volume":"152","author":"Chavez de Paz Villanueva","year":"2017","journal-title":"JAMA Surgery"}],"container-title":["European Journal of Surgical Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0748798321007800?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0748798321007800?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T01:40:25Z","timestamp":1760060425000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0748798321007800"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,4]]},"references-count":79,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2022,4]]}},"alternative-id":["S0748798321007800"],"URL":"https:\/\/doi.org\/10.1016\/j.ejso.2021.10.030","relation":{},"ISSN":["0748-7983"],"issn-type":[{"value":"0748-7983","type":"print"}],"subject":[],"published":{"date-parts":[[2022,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Advances and controversies in management of breast ductal carcinoma in situ (DCIS)","name":"articletitle","label":"Article Title"},{"value":"European Journal of Surgical Oncology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ejso.2021.10.030","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Elsevier Ltd, BASO ~ The Association for Cancer Surgery, and the European Society of Surgical Oncology. All rights reserved.","name":"copyright","label":"Copyright"}]}}