{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T03:43:26Z","timestamp":1791258206455,"version":"4.1.0"},"reference-count":41,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2022,6,1]],"date-time":"2022-06-01T00:00:00Z","timestamp":1654041600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,6,1]],"date-time":"2022-06-01T00:00:00Z","timestamp":1654041600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","ejso.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Surgical Oncology"],"published-print":{"date-parts":[[2022,6]]},"DOI":"10.1016\/j.ejso.2022.04.001","type":"journal-article","created":{"date-parts":[[2022,4,5]],"date-time":"2022-04-05T21:19:15Z","timestamp":1649193555000},"page":"1272-1279","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":19,"title":["Preoperative prediction of central lymph node metastasis in cN0T1\/T2 papillary thyroid carcinoma: A nomogram based on clinical and ultrasound characteristics"],"prefix":"10.1016","volume":"48","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2915-5076","authenticated-orcid":false,"given":"Juncheng","family":"Li","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peng","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tao","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lingfan","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shengdong","family":"He","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiang","family":"Ai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hualin","family":"Xiao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2828-5717","authenticated-orcid":false,"given":"Gang","family":"Xue","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ejso.2022.04.001_bib1","first-page":"209","article-title":"Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries","volume":"71","author":"Sung","year":"2021","journal-title":"Ca - Cancer J Clin"},{"key":"10.1016\/j.ejso.2022.04.001_bib2","first-page":"115","article-title":"Cancer statistics in China, 2015","volume":"66","author":"Chen","year":"2016","journal-title":"Ca - Cancer J Clin"},{"key":"10.1016\/j.ejso.2022.04.001_bib3","first-page":"1","article-title":"American thyroid association management guidelines for adult patients with thyroid nodules and differentiated thyroid cancer: the American thyroid association guidelines task force on thyroid nodules and differentiated thyroid cancer","volume":"26","author":"Haugen","year":"2015","journal-title":"Thyroid 2016"},{"key":"10.1016\/j.ejso.2022.04.001_bib4","doi-asserted-by":"crossref","first-page":"514","DOI":"10.1002\/ijc.33537","article-title":"Thyroid cancer and its associated factors: a population-based case-control study","volume":"149","author":"Parad","year":"2021","journal-title":"Int J Cancer"},{"key":"10.1016\/j.ejso.2022.04.001_bib5","doi-asserted-by":"crossref","DOI":"10.1097\/MD.0000000000005450","article-title":"Prognosis of papillary thyroid carcinoma in elderly patients after thyroid resection: a retrospective cohort analysis","volume":"95","author":"Chereau","year":"2016","journal-title":"Medicine (Baltim)"},{"key":"10.1016\/j.ejso.2022.04.001_bib6","doi-asserted-by":"crossref","first-page":"2834","DOI":"10.1210\/jc.2013-2118","article-title":"Differences in the recurrence and mortality outcomes rates of incidental and nonincidental papillary thyroid microcarcinoma: a systematic review and meta-analysis of 21 329 person-years of follow-up","volume":"99","author":"Mehanna","year":"2014","journal-title":"J\u00a0Clin Endocrinol Metab"},{"key":"10.1016\/j.ejso.2022.04.001_bib7","doi-asserted-by":"crossref","first-page":"1658","DOI":"10.3390\/cancers12061658","article-title":"Prophylactic central lymph node dissection improves disease-free survival in patients with intermediate and high risk differentiated thyroid carcinoma: a retrospective analysis on 399 patients","volume":"12","author":"Medas","year":"2020","journal-title":"Cancers"},{"issue":"11","key":"10.1016\/j.ejso.2022.04.001_bib8","doi-asserted-by":"crossref","first-page":"670","DOI":"10.1038\/s41574-018-0080-7","article-title":"Thyroid surgery for differentiated thyroid cancer - recent advances and future directions","volume":"14","author":"Wang","year":"2018","journal-title":"Nat Rev Endocrinol"},{"key":"10.1016\/j.ejso.2022.04.001_bib9","doi-asserted-by":"crossref","first-page":"2370","DOI":"10.1200\/JCO.2014.59.8391","article-title":"Presence and number of lymph node metastases are associated with compromised survival for patients younger than age 45 Years with papillary thyroid cancer","volume":"33","author":"Adam","year":"2015","journal-title":"J\u00a0Clin Oncol"},{"key":"10.1016\/j.ejso.2022.04.001_bib10","series-title":"Chinese society of clinical oncology (CSCO) guidelines for diagnosis and treatment of head and neck tumors","author":"Guidelines Committee of Chinese Society of Clinical Oncology","year":"2020"},{"key":"10.1016\/j.ejso.2022.04.001_bib11","doi-asserted-by":"crossref","first-page":"1671","DOI":"10.1016\/j.ejso.2018.08.005","article-title":"Decision making for the central compartment in differentiated thyroid cancer","volume":"44","author":"Gon\u00e7alves Filho","year":"2018","journal-title":"Eur J Surg Oncol"},{"key":"10.1016\/j.ejso.2022.04.001_bib12","doi-asserted-by":"crossref","first-page":"853","DOI":"10.1016\/j.jamcollsurg.2016.02.001","article-title":"Prophylactic central neck dissection might not Be necessary in papillary thyroid carcinoma: analysis of 11,569 cases from a single institution","volume":"222","author":"Kim","year":"2016","journal-title":"J\u00a0Am Coll Surg"},{"key":"10.1016\/j.ejso.2022.04.001_bib13","doi-asserted-by":"crossref","first-page":"1584","DOI":"10.1007\/s00268-013-2020-y","article-title":"Prophylactic lymph node dissection in papillary thyroid carcinoma: is there a place for lateral neck dissection?","volume":"37","author":"Ducoudray","year":"2013","journal-title":"World J Surg"},{"key":"10.1016\/j.ejso.2022.04.001_bib14","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1089\/thy.2009.1578","article-title":"The pros and cons of prophylactic central compartment lymph node dissection for papillary thyroid carcinoma","volume":"19","author":"Mazzaferri","year":"2009","journal-title":"Thyroid"},{"key":"10.1016\/j.ejso.2022.04.001_bib15","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1097\/SLA.0b013e31824b7b68","article-title":"Optimization of staging of the neck with prophylactic central and lateral neck dissection for papillary thyroid carcinoma","volume":"255","author":"Hartl","year":"2012","journal-title":"Ann Surg"},{"key":"10.1016\/j.ejso.2022.04.001_bib16","doi-asserted-by":"crossref","first-page":"1316","DOI":"10.1210\/jc.2014-3825","article-title":"Prophylactic central compartment lymph node dissection in papillary thyroid carcinoma: clinical implications derived from the first prospective randomized controlled single institution study","volume":"100","author":"Viola","year":"2015","journal-title":"J\u00a0Clin Endocrinol Metab"},{"key":"10.1016\/j.ejso.2022.04.001_bib17","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1001\/jamaoto.2015.0786","article-title":"Long-term results of observation vs prophylactic selective level VI neck dissection for papillary thyroid carcinoma at a cancer center","volume":"141","author":"Ywata de Carvalho","year":"2015","journal-title":"JAMA Otolaryngol Head Neck Surg"},{"key":"10.1016\/j.ejso.2022.04.001_bib18","first-page":"1781","article-title":"The risk of hypoparathyroidism after central compartment lymph node dissection in the surgical treatment of pT1, N0 thyroid papillary carcinoma","volume":"20","author":"Aydin","year":"2016","journal-title":"Eur Rev Med Pharmacol Sci"},{"key":"10.1016\/j.ejso.2022.04.001_bib19","doi-asserted-by":"crossref","first-page":"1981","DOI":"10.1016\/j.ejso.2017.08.001","article-title":"The central compartment - center of controversy, confusion, and concern in management of differentiated thyroid cancer","volume":"43","author":"Shaha","year":"2017","journal-title":"Eur J Surg Oncol"},{"key":"10.1016\/j.ejso.2022.04.001_bib20","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/j.ejrad.2019.01.006","article-title":"Meta-analysis of ultrasound for cervical lymph nodes in papillary thyroid cancer: diagnosis of central and lateral compartment nodal metastases","volume":"112","author":"Zhao","year":"2019","journal-title":"Eur J Radiol"},{"key":"10.1016\/j.ejso.2022.04.001_bib21","doi-asserted-by":"crossref","first-page":"1272","DOI":"10.1002\/hed.21594","article-title":"Coexistence of Hashimoto's thyroiditis with papillary thyroid carcinoma: the influence of lymph node metastasis","volume":"33","author":"Kim","year":"2011","journal-title":"Head Neck"},{"key":"10.1016\/j.ejso.2022.04.001_bib22","doi-asserted-by":"crossref","first-page":"622","DOI":"10.4158\/EP161208.GL","article-title":"American association of clinical endocrinologists, american college of endocrinology, and associazione medici endocrinologi medical guidelines for clinical practice for the diagnosis and management of thyroid nodules--2016 update","volume":"22","author":"Gharib","year":"2016","journal-title":"Endocr Pract"},{"key":"10.1016\/j.ejso.2022.04.001_bib23","doi-asserted-by":"crossref","first-page":"713475","DOI":"10.3389\/fendo.2021.713475","article-title":"Preoperatively predicting the central lymph node metastasis for papillary thyroid cancer patients with Hashimoto's thyroiditis","volume":"12","author":"Min","year":"2021","journal-title":"Front Endocrinol"},{"key":"10.1016\/j.ejso.2022.04.001_bib24","first-page":"1","article-title":"Regularization paths for generalized linear models via coordinate descent","volume":"33","author":"Friedman","year":"2010","journal-title":"J\u00a0Stat Software"},{"key":"10.1016\/j.ejso.2022.04.001_bib25","doi-asserted-by":"crossref","first-page":"e173","DOI":"10.1016\/S1470-2045(14)71116-7","article-title":"Nomograms in oncology: more than meets the eye","volume":"16","author":"Balachandran","year":"2015","journal-title":"Lancet Oncol"},{"key":"10.1016\/j.ejso.2022.04.001_bib26","doi-asserted-by":"crossref","first-page":"524","DOI":"10.1002\/cncr.21653","article-title":"Clinically significant prognostic factors for differentiated thyroid carcinoma: a population-based, nested case-control study","volume":"106","author":"Lundgren","year":"2006","journal-title":"Cancer"},{"key":"10.1016\/j.ejso.2022.04.001_bib27","doi-asserted-by":"crossref","first-page":"1020","DOI":"10.1002\/bjs.10144","article-title":"Risk factors for recurrence in patients with papillary thyroid carcinoma undergoing modified radical neck dissection","volume":"103","author":"Lee","year":"2016","journal-title":"Br J Surg"},{"key":"10.1016\/j.ejso.2022.04.001_bib28","doi-asserted-by":"crossref","first-page":"622","DOI":"10.1186\/s12885-019-5835-6","article-title":"Risk factor analysis for predicting cervical lymph node metastasis in papillary thyroid carcinoma: a study of 966 patients","volume":"19","author":"Liu","year":"2019","journal-title":"BMC Cancer"},{"key":"10.1016\/j.ejso.2022.04.001_bib29","doi-asserted-by":"crossref","first-page":"1482","DOI":"10.1007\/s12094-019-02076-0","article-title":"Predictive factors for central lymph node and lateral cervical lymph node metastases in papillary thyroid carcinoma","volume":"21","author":"Feng","year":"2019","journal-title":"Clin Transl Oncol"},{"key":"10.1016\/j.ejso.2022.04.001_bib30","doi-asserted-by":"crossref","first-page":"1327","DOI":"10.1007\/s00405-016-4302-0","article-title":"The incidence and risk factors for central lymph node metastasis in cN0 papillary thyroid microcarcinoma: a meta-analysis","volume":"274","author":"Liu","year":"2017","journal-title":"Eur Arch Oto-Rhino-Laryngol"},{"key":"10.1016\/j.ejso.2022.04.001_bib31","doi-asserted-by":"crossref","first-page":"5307","DOI":"10.2147\/OTT.S107913","article-title":"Risk prediction and clinical model building for lymph node metastasis in papillary thyroid microcarcinoma","volume":"9","author":"Lin","year":"2016","journal-title":"OncoTargets Ther"},{"key":"10.1016\/j.ejso.2022.04.001_bib32","doi-asserted-by":"crossref","DOI":"10.1177\/1533033819831713","article-title":"Prediction of lymph node metastasis in patients with papillary thyroid carcinoma: a radiomics method based on preoperative ultrasound images","volume":"18","author":"Liu","year":"2019","journal-title":"Technol Cancer Res Treat"},{"key":"10.1016\/j.ejso.2022.04.001_bib33","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1016\/j.ijsu.2018.05.023","article-title":"Nomogram for predicting central lymph node metastasis in papillary thyroid microcarcinoma: a retrospective cohort study of 8668 patients","volume":"55","author":"Wang","year":"2018","journal-title":"Int J Surg"},{"key":"10.1016\/j.ejso.2022.04.001_bib34","doi-asserted-by":"crossref","first-page":"613974","DOI":"10.3389\/fendo.2021.613974","article-title":"Nomogram for preoperative estimation of cervical lymph node metastasis risk in papillary thyroid microcarcinoma","volume":"12","author":"Sun","year":"2021","journal-title":"Front Endocrinol"},{"key":"10.1016\/j.ejso.2022.04.001_bib35","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1038\/s41370-021-00329-1","article-title":"Neighborhood characteristics associated with COVID-19 burden-the modifying effect of age","volume":"31","author":"Zhang","year":"2021","journal-title":"J\u00a0Expo Sci Environ Epidemiol"},{"key":"10.1016\/j.ejso.2022.04.001_bib36","doi-asserted-by":"crossref","first-page":"63","DOI":"10.4174\/astr.2015.88.2.63","article-title":"Predictive factors of central lymph node metastasis in papillary thyroid carcinoma","volume":"88","author":"Ahn","year":"2015","journal-title":"Ann Surg Treat Res"},{"key":"10.1016\/j.ejso.2022.04.001_bib37","first-page":"55","article-title":"Differentiated and anaplastic thyroid carcinoma: major changes in the American Joint Committee on Cancer eighth edition cancer staging manual","volume":"68","author":"Perrier","year":"2018","journal-title":"Ca - Cancer J Clin"},{"key":"10.1016\/j.ejso.2022.04.001_bib38","doi-asserted-by":"crossref","first-page":"666315","DOI":"10.3389\/fendo.2021.666315","article-title":"A\u00a0nomogram based on clinical and ultrasound characteristics to predict central lymph node metastasis of papillary thyroid carcinoma","volume":"12","author":"Feng","year":"2021","journal-title":"Front Endocrinol"},{"key":"10.1016\/j.ejso.2022.04.001_bib39","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1111\/cen.14302","article-title":"A\u00a0nomogram model based on the preoperative clinical characteristics of papillary thyroid carcinoma with Hashimoto's thyroiditis to predict central lymph node metastasis","volume":"94","author":"Zhao","year":"2021","journal-title":"Clin Endocrinol"},{"key":"10.1016\/j.ejso.2022.04.001_bib40","doi-asserted-by":"crossref","DOI":"10.1016\/j.eprac.2021.06.010","article-title":"Nomogram to assess the risk of central cervical lymph node metastasis in patients with clinical N0 papillary thyroid carcinoma","author":"Sun","year":"2021","journal-title":"Endocr Pract"},{"key":"10.1016\/j.ejso.2022.04.001_bib41","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/S0167-5877(00)00115-X","article-title":"Principles and practical application of the receiver-operating characteristic analysis for diagnostic tests","volume":"45","author":"Greiner","year":"2000","journal-title":"Prev Vet Med"}],"container-title":["European Journal of Surgical Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S074879832200378X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S074879832200378X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T01:44:00Z","timestamp":1760060640000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S074879832200378X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,6]]},"references-count":41,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2022,6]]}},"alternative-id":["S074879832200378X"],"URL":"https:\/\/doi.org\/10.1016\/j.ejso.2022.04.001","relation":{},"ISSN":["0748-7983"],"issn-type":[{"value":"0748-7983","type":"print"}],"subject":[],"published":{"date-parts":[[2022,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Preoperative prediction of central lymph node metastasis in cN0T1\/T2 papillary thyroid carcinoma: A nomogram based on clinical and ultrasound characteristics","name":"articletitle","label":"Article Title"},{"value":"European Journal of Surgical Oncology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ejso.2022.04.001","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Elsevier Ltd, BASO ~ The Association for Cancer Surgery, and the European Society of Surgical Oncology. All rights reserved.","name":"copyright","label":"Copyright"}]}}