{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,31]],"date-time":"2026-01-31T00:45:34Z","timestamp":1769820334503,"version":"3.49.0"},"reference-count":29,"publisher":"Elsevier BV","issue":"10","license":[{"start":{"date-parts":[[2022,10,1]],"date-time":"2022-10-01T00:00:00Z","timestamp":1664582400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,10,1]],"date-time":"2022-10-01T00:00:00Z","timestamp":1664582400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,6,15]],"date-time":"2022-06-15T00:00:00Z","timestamp":1655251200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","ejso.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Surgical Oncology"],"published-print":{"date-parts":[[2022,10]]},"DOI":"10.1016\/j.ejso.2022.05.031","type":"journal-article","created":{"date-parts":[[2022,6,2]],"date-time":"2022-06-02T12:21:17Z","timestamp":1654172477000},"page":"2195-2201","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":7,"title":["Impact of multicentre diagnostic workup in patients with pancreatic cancer on repeated diagnostic investigations, time-to-diagnosis and time-to-treatment: A nationwide analysis"],"prefix":"10.1016","volume":"48","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0171-5986","authenticated-orcid":false,"given":"Jana S.","family":"Hopstaken","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0677-888X","authenticated-orcid":false,"given":"Pauline A.J.","family":"Vissers","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6109-9310","authenticated-orcid":false,"given":"Rutger","family":"Quispel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2578-1766","authenticated-orcid":false,"given":"Judith","family":"de Vos-Geelen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lodewijk A.A.","family":"Brosens","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ignace H.J.T.","family":"de Hingh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lydia G.","family":"van der Geest","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marc G.","family":"Besselink","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kees J.H.M.","family":"van Laarhoven","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martijn W.J.","family":"Stommel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"3","key":"10.1016\/j.ejso.2022.05.031_bib1","doi-asserted-by":"crossref","first-page":"404","DOI":"10.1002\/bjs.8664","article-title":"Impact of nationwide centralization of pancreaticoduodenectomy on hospital mortality","volume":"99","author":"de Wilde","year":"2012","journal-title":"Br J Surg"},{"issue":"10","key":"10.1016\/j.ejso.2022.05.031_bib2","doi-asserted-by":"crossref","first-page":"1455","DOI":"10.1002\/bjs.7581","article-title":"Improving outcome for patients with pancreatic cancer through centralization","volume":"98","author":"Lemmens","year":"2011","journal-title":"Br J Surg"},{"issue":"2","key":"10.1016\/j.ejso.2022.05.031_bib3","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1016\/j.amjsurg.2017.07.033","article-title":"Centralisation for resection of the pancreatic head: a comparison of operative factors and early outcomes during the evolving unit and tertiary unit phases at a UK institution","volume":"216","author":"Kostalas","year":"2018","journal-title":"Am J Surg"},{"issue":"10","key":"10.1016\/j.ejso.2022.05.031_bib4","doi-asserted-by":"crossref","first-page":"2081","DOI":"10.1007\/s11605-019-04215-y","article-title":"Centralization of pancreatic surgery in Europe","volume":"23","author":"Polonski","year":"2019","journal-title":"J\u00a0Gastrointest Surg"},{"issue":"8","key":"10.1016\/j.ejso.2022.05.031_bib5","doi-asserted-by":"crossref","first-page":"1000","DOI":"10.1002\/bjs.9468","article-title":"Impact of centralization of pancreatic cancer surgery on resection rates and survival","volume":"101","author":"Gooiker","year":"2014","journal-title":"Br J Surg"},{"key":"10.1016\/j.ejso.2022.05.031_bib6","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1016\/j.ijsu.2016.06.046","article-title":"Improving pancreas surgery over time: performance factors related to transition of care and patient volume","volume":"32","author":"S\u00f8reide","year":"2016","journal-title":"Int J Surg"},{"issue":"7","key":"10.1016\/j.ejso.2022.05.031_bib7","doi-asserted-by":"crossref","first-page":"826","DOI":"10.1093\/bjs\/znaa146","article-title":"Effect of centralization and regionalization of pancreatic surgery on resection rates and survival","volume":"108","author":"Latenstein","year":"2021","journal-title":"Br J Surg"},{"issue":"5","key":"10.1016\/j.ejso.2022.05.031_bib8","doi-asserted-by":"crossref","first-page":"712","DOI":"10.1097\/SLA.0000000000002965","article-title":"Toward a consensus on centralization in surgery","volume":"268","author":"Vonlanthen","year":"2018","journal-title":"Ann Surg"},{"issue":"7","key":"10.1016\/j.ejso.2022.05.031_bib9","doi-asserted-by":"crossref","first-page":"1218","DOI":"10.1007\/s11605-013-2213-6","article-title":"Unnecessary tests and procedures in patients presenting with solid tumors of the pancreas","volume":"17","author":"Cooper","year":"2013","journal-title":"J\u00a0Gastrointest Surg"},{"key":"10.1016\/j.ejso.2022.05.031_bib10","unstructured":"National Comprehensive Cancer Network (NCCN). Pancreatic Adenocarcinoma (version 2.2021). https:\/\/www.nccn.org\/guidelines\/guidelines-detail?category=1&id=1455 Accessed August 18, 2021."},{"issue":"4","key":"10.1016\/j.ejso.2022.05.031_bib11","doi-asserted-by":"crossref","first-page":"e102","DOI":"10.1097\/SLA.0000000000003779","article-title":"Establishing and coordinating a nationwide multidisciplinary study group: lessons learned by the Dutch pancreatic cancer group","volume":"271","author":"Strijker","year":"2020","journal-title":"Ann Surg"},{"issue":"9596","key":"10.1016\/j.ejso.2022.05.031_bib12","doi-asserted-by":"crossref","first-page":"1453","DOI":"10.1016\/S0140-6736(07)61602-X","article-title":"The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement: guidelines for reporting observational studies","volume":"370","author":"von Elm","year":"2007","journal-title":"Lancet"},{"key":"10.1016\/j.ejso.2022.05.031_bib14","unstructured":"National Guideline Pancreatic Cancer. Richtlijn Pancreas Carcinoom - Federatie Medisch Specialisten. Available at: https:\/\/richtlijnendatabase.nl\/richtlijn\/pancreascarcinoom\/startpagina.html. Accessed."},{"issue":"8","key":"10.1016\/j.ejso.2022.05.031_bib15","doi-asserted-by":"crossref","first-page":"1723","DOI":"10.1016\/j.pan.2020.10.032","article-title":"Nationwide compliance with a multidisciplinary guideline on pancreatic cancer during 6-year follow-up","volume":"20","author":"Mackay","year":"2020","journal-title":"Pancreatology"},{"key":"10.1016\/j.ejso.2022.05.031_bib16","series-title":"Multilevel modelling for public health and health services research","author":"Leyland","year":"2020"},{"issue":"1","key":"10.1016\/j.ejso.2022.05.031_bib17","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1186\/s12913-021-06431-2","article-title":"Continuity of care experienced by patients in a multi-institutional pancreatic care network: a pilot study","volume":"21","author":"Hopstaken","year":"2021","journal-title":"BMC Health Serv Res"},{"key":"10.1016\/j.ejso.2022.05.031_bib18","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/j.ejca.2019.11.002","article-title":"Nationwide trends in incidence, treatment and survival of pancreatic ductal adenocarcinoma","volume":"125","author":"Latenstein","year":"2020","journal-title":"Eur J Cancer"},{"issue":"11","key":"10.1016\/j.ejso.2022.05.031_bib19","doi-asserted-by":"crossref","first-page":"1568","DOI":"10.1002\/bjs.10602","article-title":"Nationwide outcomes in patients undergoing surgical exploration without resection for pancreatic cancer","volume":"104","author":"van der Geest","year":"2017","journal-title":"Br J Surg"},{"key":"10.1016\/j.ejso.2022.05.031_bib20","doi-asserted-by":"crossref","DOI":"10.21037\/apc.2018.02.01","article-title":"Diagnostic intervals and pancreatic ductal adenocarcinoma (PDAC) resectability: a single-center retrospective analysis","volume":"1","author":"Deshwar","year":"2018","journal-title":"Ann Pancreat Cancer"},{"issue":"3","key":"10.1016\/j.ejso.2022.05.031_bib21","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1002\/bjs.10046","article-title":"Impact of delay between imaging and treatment in patients with potentially curable pancreatic cancer","volume":"103","author":"Sanjeevi","year":"2016","journal-title":"Br J Surg"},{"issue":"9","key":"10.1016\/j.ejso.2022.05.031_bib22","doi-asserted-by":"crossref","first-page":"644","DOI":"10.1111\/j.1477-2574.2010.00217.x","article-title":"Increasing time delay from presentation until surgical referral for hepatobiliary malignancies","volume":"12","author":"Croome","year":"2010","journal-title":"HPB"},{"issue":"8","key":"10.1016\/j.ejso.2022.05.031_bib23","doi-asserted-by":"crossref","first-page":"853","DOI":"10.1002\/jso.23338","article-title":"The effect of wait times on oncological outcomes from periampullary adenocarcinomas","volume":"107","author":"McLean","year":"2013","journal-title":"J\u00a0Surg Oncol"},{"issue":"5","key":"10.1016\/j.ejso.2022.05.031_bib24","doi-asserted-by":"crossref","first-page":"884","DOI":"10.1002\/bjs5.50319","article-title":"Impact of time interval between multidisciplinary team meeting and intended pancreatoduodenectomy on oncological outcomes","volume":"4","author":"Steen","year":"2020","journal-title":"BJS Open"},{"issue":"1","key":"10.1016\/j.ejso.2022.05.031_bib25","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1002\/pon.4093","article-title":"Perceived diagnostic delay and cancer-related distress: a cross-sectional study of patients with colorectal cancer","volume":"26","author":"Miles","year":"2017","journal-title":"Psycho Oncol"},{"issue":"2","key":"10.1016\/j.ejso.2022.05.031_bib26","first-page":"995","article-title":"Diagnostic delay causes more psychological distress in female than in male cancer patients","volume":"16","author":"Risberg","year":"1996","journal-title":"Anticancer Res"},{"issue":"17","key":"10.1016\/j.ejso.2022.05.031_bib27","doi-asserted-by":"crossref","first-page":"5907","DOI":"10.1002\/cam4.4145","article-title":"The bigger picture of shared decision making: a service design perspective using the care path of locally advanced pancreatic cancer as a case","volume":"10","author":"Griffioen","year":"2021","journal-title":"Cancer Med"},{"issue":"6","key":"10.1016\/j.ejso.2022.05.031_bib28","doi-asserted-by":"crossref","first-page":"704","DOI":"10.6004\/jnccn.2020.7528","article-title":"Patient satisfaction and quality of life before and after treatment of pancreatic and periampullary cancer: a prospective multicenter study","volume":"18","author":"Mackay","year":"2020","journal-title":"J\u00a0Natl Compr Cancer Netw"},{"issue":"2","key":"10.1016\/j.ejso.2022.05.031_bib29","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1097\/MPA.0000000000000484","article-title":"Identifying factors influencing pancreatic cancer management to inform quality improvement efforts and future research: a scoping systematic review","volume":"45","author":"Gagliardi","year":"2016","journal-title":"Pancreas"},{"issue":"6","key":"10.1016\/j.ejso.2022.05.031_bib30","doi-asserted-by":"crossref","DOI":"10.1136\/esmoopen-2020-001051","article-title":"Bratislava Statement: consensus recommendations for improving pancreatic cancer care","volume":"5","author":"Prades","year":"2020","journal-title":"ESMO Open"}],"container-title":["European Journal of Surgical Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0748798322004814?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0748798322004814?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T01:43:35Z","timestamp":1760060615000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0748798322004814"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,10]]},"references-count":29,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2022,10]]}},"alternative-id":["S0748798322004814"],"URL":"https:\/\/doi.org\/10.1016\/j.ejso.2022.05.031","relation":{},"ISSN":["0748-7983"],"issn-type":[{"value":"0748-7983","type":"print"}],"subject":[],"published":{"date-parts":[[2022,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Impact of multicentre diagnostic workup in patients with pancreatic cancer on repeated diagnostic investigations, time-to-diagnosis and time-to-treatment: A nationwide analysis","name":"articletitle","label":"Article Title"},{"value":"European Journal of Surgical Oncology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ejso.2022.05.031","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 The Authors. Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}]}}