{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,15]],"date-time":"2026-07-15T15:05:50Z","timestamp":1784127950389,"version":"3.55.0"},"reference-count":25,"publisher":"Elsevier BV","issue":"12","license":[{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,12,7]],"date-time":"2023-12-07T00:00:00Z","timestamp":1701907200000},"content-version":"am","delay-in-days":371,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","ejso.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Surgical Oncology"],"published-print":{"date-parts":[[2022,12]]},"DOI":"10.1016\/j.ejso.2022.06.015","type":"journal-article","created":{"date-parts":[[2022,6,16]],"date-time":"2022-06-16T02:19:26Z","timestamp":1655345966000},"page":"2502-2508","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":11,"title":["Minimum radial margin in pelvic exenteration for locally advanced or recurrent rectal cancer"],"prefix":"10.1016","volume":"48","author":[{"given":"Toshisada","family":"Aiba","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9669-5860","authenticated-orcid":false,"given":"Kay","family":"Uehara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuta","family":"Tsuyuki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6560-1806","authenticated-orcid":false,"given":"Atsushi","family":"Ogura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuki","family":"Murata","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takashi","family":"Mizuno","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junpei","family":"Yamaguchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7176-7581","authenticated-orcid":false,"given":"Toshio","family":"Kokuryo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yukihiro","family":"Yokoyama","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8247-7050","authenticated-orcid":false,"given":"Tomoki","family":"Ebata","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"10","key":"10.1016\/j.ejso.2022.06.015_bib1","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1002\/bjs.1800691019","article-title":"The mesorectum in rectal cancer surgery--the clue to pelvic recurrence?","volume":"69","author":"Heald","year":"1982","journal-title":"Br J Surg"},{"issue":"4","key":"10.1016\/j.ejso.2022.06.015_bib2","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1002\/bjs.7372","article-title":"Northern Region Colorectal Cancer Audit Group. Effect of the circumferential resection margin on survival following rectal cancer surgery","volume":"98","author":"Kelly","year":"2011","journal-title":"Br J Surg"},{"issue":"2","key":"10.1016\/j.ejso.2022.06.015_bib3","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1200\/JCO.2007.12.7027","article-title":"What is the role for the circumferential margin in the modern treatment of rectal cancer?","volume":"26","author":"Nagtegaal","year":"2008","journal-title":"J\u00a0Clin Oncol"},{"issue":"8514","key":"10.1016\/j.ejso.2022.06.015_bib4","doi-asserted-by":"crossref","first-page":"996","DOI":"10.1016\/S0140-6736(86)92612-7","article-title":"Local recurrence of rectal adenocarcinoma due to inadequate surgical resection. Histopathological study of lateral tumour spread and surgical excision","volume":"2","author":"Quirke","year":"1986","journal-title":"Lancet"},{"issue":"8924","key":"10.1016\/j.ejso.2022.06.015_bib5","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1016\/S0140-6736(94)92206-3","article-title":"Role of circumferential margin involvement in the local recurrence of rectal cancer","volume":"344","author":"Adam","year":"1994","journal-title":"Lancet"},{"issue":"6","key":"10.1016\/j.ejso.2022.06.015_bib6","doi-asserted-by":"crossref","first-page":"781","DOI":"10.1002\/bjs.1800830617","article-title":"Prognostic significance of radial margins of clearance in rectal cancer","volume":"83","author":"de Haas-Kock","year":"1996","journal-title":"Br J Surg"},{"issue":"4","key":"10.1016\/j.ejso.2022.06.015_bib7","doi-asserted-by":"crossref","first-page":"1199","DOI":"10.1245\/s10434-011-2036-1","article-title":"Adverse features on rectal MRI identify a high-risk group that may benefit from more intensive preoperative staging and treatment","volume":"19","author":"Hunter","year":"2012","journal-title":"Ann Surg Oncol"},{"issue":"1","key":"10.1016\/j.ejso.2022.06.015_bib8","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1200\/JCO.2012.45.3258","article-title":"Preoperative magnetic resonance imaging assessment of circumferential resection margin predicts disease-free survival and local recurrence: 5-year follow-up results of the MERCURY study","volume":"32","author":"Taylor","year":"2014","journal-title":"J\u00a0Clin Oncol"},{"issue":"suppl_4","key":"10.1016\/j.ejso.2022.06.015_bib9","doi-asserted-by":"crossref","first-page":"iv22","DOI":"10.1093\/annonc\/mdx224","article-title":"Rectal cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up","volume":"28","author":"Glynne-Jones","year":"2017","journal-title":"Ann Oncol"},{"issue":"7","key":"10.1016\/j.ejso.2022.06.015_bib10","doi-asserted-by":"crossref","first-page":"874","DOI":"10.6004\/jnccn.2018.0061","article-title":"Rectal cancer, version 2.2018, NCCN clinical practice guidelines in Oncology","volume":"16","author":"Benson","year":"2018","journal-title":"J\u00a0Natl Compr Cancer Netw"},{"issue":"5","key":"10.1016\/j.ejso.2022.06.015_bib11","doi-asserted-by":"crossref","first-page":"612","DOI":"10.1245\/ASO.2006.03.082","article-title":"Pelvic exenteration for advanced pelvic malignancies","volume":"13","author":"Pawlik","year":"2006","journal-title":"Ann Surg Oncol"},{"issue":"7","key":"10.1016\/j.ejso.2022.06.015_bib12","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1097\/DCR.0000000000000839","article-title":"Pelvic exenteration surgery: the evolution of radical surgical techniques for advanced and recurrent pelvic malignancy","volume":"60","author":"Brown","year":"2017","journal-title":"Dis Colon Rectum"},{"issue":"6","key":"10.1016\/j.ejso.2022.06.015_bib13","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1016\/j.ejso.2016.02.016","article-title":"Outcomes of pelvic exenteration for locally advanced primary rectal cancer: overall survival and quality of life","volume":"42","author":"Quyn","year":"2016","journal-title":"Eur J Surg Oncol"},{"issue":"2","key":"10.1016\/j.ejso.2022.06.015_bib14","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1097\/SLA.0000000000002528","article-title":"Surgical and survival outcomes following pelvic exenteration for locally advanced primary rectal cancer: results from an international collaboration","volume":"269","year":"2019","journal-title":"Ann Surg"},{"issue":"3","key":"10.1016\/j.ejso.2022.06.015_bib15","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1016\/j.ejso.2014.11.005","article-title":"Aggressive surgical treatment with bony pelvic resection for locally recurrent rectal cancer","volume":"41","author":"Uehara","year":"2015","journal-title":"Eur J Surg Oncol"},{"issue":"3","key":"10.1016\/j.ejso.2022.06.015_bib16","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1097\/DCR.0000000000000737","article-title":"Systematic review of pelvic exenteration with en bloc sacrectomy for recurrent rectal adenocarcinoma: R0 resection predicts disease-free survival","volume":"60","author":"Sasikumar","year":"2017","journal-title":"Dis Colon Rectum"},{"issue":"3","key":"10.1016\/j.ejso.2022.06.015_bib17","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1007\/s10350-007-9152-9","article-title":"Extended radical resection: the choice for locally recurrent rectal cancer","volume":"51","author":"Heriot","year":"2008","journal-title":"Dis Colon Rectum"},{"key":"10.1016\/j.ejso.2022.06.015_bib18","series-title":"Atlas of advanced operative surgery","first-page":"430","article-title":"Total pelvic exenteration with distal sacrectomy for fixed locally recurrent rectal cancer","author":"Moriya","year":"2013"},{"issue":"1","key":"10.1016\/j.ejso.2022.06.015_bib19","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1007\/s00464-015-4172-3","article-title":"Initial experience of laparoscopic pelvic exenteration and comparison with conventional open surgery","volume":"30","author":"Uehara","year":"2016","journal-title":"Surg Endosc"},{"key":"10.1016\/j.ejso.2022.06.015_bib20","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1016\/j.suronc.2020.09.001","article-title":"The role of surgery for locally recurrent and second recurrent rectal cancer with metastatic disease","volume":"35","author":"Tanaka","year":"2020","journal-title":"Surg Oncol"},{"issue":"1","key":"10.1016\/j.ejso.2022.06.015_bib21","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s10147-019-01485-z","article-title":"Japanese Society for Cancer of the Colon and Rectum (JSCCR) guidelines 2019 for the treatment of colorectal cancer","volume":"25","author":"Hashiguchi","year":"2020","journal-title":"Int J Clin Oncol"},{"issue":"1","key":"10.1016\/j.ejso.2022.06.015_bib22","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1097\/SLA.0000000000003834","article-title":"What constitutes a clear margin in patients with locally recurrent rectal cancer undergoing pelvic exenteration?","volume":"275","author":"Koh","year":"2022","journal-title":"Ann Surg"},{"issue":"8","key":"10.1016\/j.ejso.2022.06.015_bib23","doi-asserted-by":"crossref","first-page":"1998","DOI":"10.1111\/codi.15698","article-title":"The role of intraoperative radiotherapy in advanced rectal cancer: a meta-analysis","volume":"23","author":"Fahy","year":"2021","journal-title":"Colorectal Dis"},{"issue":"1","key":"10.1016\/j.ejso.2022.06.015_bib24","doi-asserted-by":"crossref","first-page":"69","DOI":"10.4251\/wjgo.v13.i1.69","article-title":"Efficacy and safety of intraoperative radiotherapy in rectal cancer: a systematic review and meta-analysis","volume":"13","author":"Liu","year":"2021","journal-title":"World J Gastrointest Oncol"},{"issue":"7","key":"10.1016\/j.ejso.2022.06.015_bib25","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1097\/DCR.0000000000000388","article-title":"The importance of a minimal tumor-free resection margin in locally recurrent rectal cancer","volume":"58","author":"Alberda","year":"2015","journal-title":"Dis Colon Rectum"}],"container-title":["European Journal of Surgical Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0748798322004991?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0748798322004991?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T01:44:28Z","timestamp":1760060668000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0748798322004991"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,12]]},"references-count":25,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2022,12]]}},"alternative-id":["S0748798322004991"],"URL":"https:\/\/doi.org\/10.1016\/j.ejso.2022.06.015","relation":{},"ISSN":["0748-7983"],"issn-type":[{"value":"0748-7983","type":"print"}],"subject":[],"published":{"date-parts":[[2022,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Minimum radial margin in pelvic exenteration for locally advanced or recurrent rectal cancer","name":"articletitle","label":"Article Title"},{"value":"European Journal of Surgical Oncology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ejso.2022.06.015","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Elsevier Ltd, BASO ~ The Association for Cancer Surgery, and the European Society of Surgical Oncology. All rights reserved.","name":"copyright","label":"Copyright"}]}}