{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,28]],"date-time":"2026-02-28T15:32:27Z","timestamp":1772292747462,"version":"3.50.1"},"reference-count":31,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2023,2,1]],"date-time":"2023-02-01T00:00:00Z","timestamp":1675209600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,2,1]],"date-time":"2023-02-01T00:00:00Z","timestamp":1675209600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,2,1]],"date-time":"2023-02-01T00:00:00Z","timestamp":1675209600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2023,2,1]],"date-time":"2023-02-01T00:00:00Z","timestamp":1675209600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2023,2,1]],"date-time":"2023-02-01T00:00:00Z","timestamp":1675209600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2023,2,1]],"date-time":"2023-02-01T00:00:00Z","timestamp":1675209600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2023,2,1]],"date-time":"2023-02-01T00:00:00Z","timestamp":1675209600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","ejso.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Surgical Oncology"],"published-print":{"date-parts":[[2023,2]]},"DOI":"10.1016\/j.ejso.2022.09.008","type":"journal-article","created":{"date-parts":[[2022,9,27]],"date-time":"2022-09-27T06:46:53Z","timestamp":1664261213000},"page":"362-367","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":12,"title":["Intermuscular extremity myxoid liposarcoma can be managed by marginal resection following neoadjuvant radiotherapy"],"prefix":"10.1016","volume":"49","author":[{"given":"Jonathan R.","family":"Perera","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1605-7960","authenticated-orcid":false,"given":"Meshal","family":"AlFaraidy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2063-7159","authenticated-orcid":false,"given":"Izuchukwu","family":"Ibe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ahmed","family":"Aoude","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8042-9856","authenticated-orcid":false,"given":"Ibtissam","family":"Acem","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michiel A.J.","family":"van de Sande","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mireille","family":"Dessureault","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert E.","family":"Turcotte","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sophie","family":"Mottard","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0717-0224","authenticated-orcid":false,"given":"Georges","family":"Basile","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marc","family":"Isler","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hugo","family":"Saint-Yves","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicholas","family":"Eastley","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jonathan","family":"Stevenson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthew T.","family":"Houdek","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter W.M.","family":"Chung","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anthony M.","family":"Griffin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter","family":"Ferguson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jay S.","family":"Wunder","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kim M.","family":"Tsoi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ejso.2022.09.008_bib1","unstructured":"WHO Classification of Tumours: Soft Tissue and Bone Tumours. Vol 3. 5th ed. International Agency for Research on Cancer; 2020."},{"issue":"12","key":"10.1016\/j.ejso.2022.09.008_bib2","doi-asserted-by":"crossref","first-page":"7903","DOI":"10.1245\/s10434-021-10091-1","article-title":"Staging and surveillance of myxoid liposarcoma: follow-up assessment and the metastatic pattern of 169 patients suggests inadequacy of current practice standards","volume":"28","author":"Visgauss","year":"2021","journal-title":"Ann Surg Oncol"},{"key":"10.1016\/j.ejso.2022.09.008_bib3","doi-asserted-by":"crossref","DOI":"10.1155\/2013\/548628","article-title":"Metastatic pattern, local relapse, and survival of patients with myxoid liposarcoma: a retrospective study of 45 patients","volume":"2013","author":"Fugl\u00f8","year":"2013","journal-title":"Sarcoma"},{"issue":"1","key":"10.1016\/j.ejso.2022.09.008_bib4","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1186\/s12885-018-4226-8","article-title":"Myxoid liposarcoma: local relapse and metastatic pattern in 43 patients","volume":"18","author":"D\u00fcrr","year":"2018","journal-title":"BMC Cancer"},{"issue":"3","key":"10.1016\/j.ejso.2022.09.008_bib5","doi-asserted-by":"crossref","first-page":"760","DOI":"10.1016\/j.ijrobp.2007.07.2337","article-title":"Excellent local control rates and distinctive patterns of failure in myxoid liposarcoma treated with conservation surgery and radiotherapy","volume":"70","author":"Guadagnolo","year":"2008","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ejso.2022.09.008_bib6","doi-asserted-by":"crossref","DOI":"10.1155\/2011\/538085","article-title":"Prognostic factors and metastatic patterns in primary myxoid\/round-cell liposarcoma","volume":"2011","author":"Haniball","year":"2011","journal-title":"Sarcoma"},{"issue":"4","key":"10.1016\/j.ejso.2022.09.008_bib7","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1007\/s10434-999-0389-5","article-title":"Myxoid liposarcoma\u2014frequency and the natural history of nonpulmonary soft tissue metastases","volume":"6","author":"Spillane","year":"1999","journal-title":"Ann Surg Oncol"},{"key":"10.1016\/j.ejso.2022.09.008_bib8","article-title":"Myxoid liposarcoma: prognostic factors and metastatic pattern in a series of 148 patients treated at a single institution","volume":"2018","author":"Muratori","year":"2018","journal-title":"Int J Surg Oncol"},{"issue":"3","key":"10.1016\/j.ejso.2022.09.008_bib9","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1007\/s00256-017-2845-9","article-title":"Early detection of metastases using whole-body MRI for initial staging and routine follow-up of myxoid liposarcoma","volume":"47","author":"Gorelik","year":"2018","journal-title":"Skeletal Radiol"},{"issue":"9325","key":"10.1016\/j.ejso.2022.09.008_bib10","doi-asserted-by":"crossref","first-page":"2235","DOI":"10.1016\/S0140-6736(02)09292-9","article-title":"Preoperative versus postoperative radiotherapy in soft- tissue sarcoma of the limbs: a randomised trial","volume":"359","author":"O'Sullivan","year":"2002","journal-title":"Lancet"},{"issue":"14","key":"10.1016\/j.ejso.2022.09.008_bib11","doi-asserted-by":"crossref","first-page":"3254","DOI":"10.1002\/cncr.24375","article-title":"Radiosensitivity translates into excellent local control in extremity myxoid liposarcoma","volume":"115","author":"Chung","year":"2009","journal-title":"Cancer"},{"key":"10.1016\/j.ejso.2022.09.008_bib12","doi-asserted-by":"crossref","DOI":"10.1155\/2018\/8029157","article-title":"Myxoid liposarcoma: treatment outcomes from chemotherapy and radiation therapy","volume":"2018","author":"Chowdhry","year":"2018","journal-title":"Sarcoma"},{"issue":"6","key":"10.1016\/j.ejso.2022.09.008_bib13","doi-asserted-by":"crossref","first-page":"838","DOI":"10.1080\/02841860601080415","article-title":"Irradiation of myxoid\/round cell liposarcoma induces volume reduction and lipoma-like morphology","volume":"46","author":"Engstr\u00f6m","year":"2009","journal-title":"Acta Oncol"},{"issue":"2","key":"10.1016\/j.ejso.2022.09.008_bib14","doi-asserted-by":"crossref","first-page":"522","DOI":"10.1016\/j.ijrobp.2004.03.009","article-title":"Radiation response: an additional unique signature of myxoid liposarcoma","volume":"60","author":"Pitson","year":"2004","journal-title":"Int J Radiat Oncol Biol Phys"},{"issue":"4","key":"10.1016\/j.ejso.2022.09.008_bib15","doi-asserted-by":"crossref","first-page":"574","DOI":"10.1016\/j.ejso.2015.12.011","article-title":"Whole-body magnetic resonance imaging in myxoid liposarcoma: a useful adjunct for the detection of extra-pulmonary metastatic disease","volume":"42","author":"Stevenson","year":"2016","journal-title":"European J Surg Oncol Ejso"},{"issue":"2","key":"10.1016\/j.ejso.2022.09.008_bib16","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1016\/S0360-3016(96)00265-9","article-title":"Liposarcoma: outcome and prognostic factors following conservation surgery and radiation therapy","volume":"36","author":"Zagars","year":"1996","journal-title":"Int J Radiat Oncol Biol Phys"},{"issue":"7","key":"10.1016\/j.ejso.2022.09.008_bib17","doi-asserted-by":"crossref","DOI":"10.1200\/JCO.2017.74.6941","article-title":"Analysis of margin classification systems for assessing the risk of local recurrence after soft tissue sarcoma resection","volume":"36","author":"Gundle","year":"2018","journal-title":"J\u00a0Clin Oncol"},{"issue":"8","key":"10.1016\/j.ejso.2022.09.008_bib18","first-page":"1149","article-title":"Classification of positive margins after resection of soft- tissue sarcoma of the limb predicts the risk of local recurrence","volume":"83-B","author":"Gerrand","year":"2001","journal-title":"Bone Joint Lett J"},{"issue":"NA","key":"10.1016\/j.ejso.2022.09.008_bib19","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1097\/01.blo.0000180057.22712.53","article-title":"Epineural dissection is a safe technique that facilitates limb salvage surgery","volume":"438","author":"Clarkson","year":"2005","journal-title":"Clin Orthop Relat Res"},{"issue":"12","key":"10.1016\/j.ejso.2022.09.008_bib20","first-page":"3977","article-title":"Prognostic impact of P53 status, TLS-CHOP fusion transcript structure, and histological grade in myxoid liposarcoma: a molecular and clinicopathologic study of 82 cases","volume":"7","author":"Antonescu","year":"2001","journal-title":"Clin Cancer Res Official J Am Assoc Cancer Res"},{"issue":"5","key":"10.1016\/j.ejso.2022.09.008_bib21","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1097\/PAS.0b013e3181963c9c","article-title":"Liposarcomas in young patients","volume":"33","author":"Alaggio","year":"2009","journal-title":"Am J Surg Pathol"},{"issue":"8","key":"10.1016\/j.ejso.2022.09.008_bib22","doi-asserted-by":"crossref","first-page":"876","DOI":"10.1016\/j.otsr.2010.05.010","article-title":"Liposarcoma of the extremities: MR imaging features and their correlation with pathologic data","volume":"96","author":"Ouni","year":"2010","journal-title":"Orthop Traumatology Surg Res"},{"issue":"4","key":"10.1016\/j.ejso.2022.09.008_bib23","doi-asserted-by":"crossref","first-page":"1007","DOI":"10.1148\/radiographics.20.4.g00jl021007","article-title":"Myxoid liposarcoma: appearance at MR imaging with histologic correlation","volume":"20","author":"Sung","year":"2000","journal-title":"Radiographics"},{"issue":"18","key":"10.1016\/j.ejso.2022.09.008_bib24","doi-asserted-by":"crossref","first-page":"2866","DOI":"10.1002\/cncr.28793","article-title":"The effect of the setting of a positive surgical margin in soft tissue sarcoma","volume":"120","author":"O'Donnell","year":"2014","journal-title":"Cancer"},{"issue":"1","key":"10.1016\/j.ejso.2022.09.008_bib25","doi-asserted-by":"crossref","DOI":"10.1001\/jamaoncol.2020.5865","article-title":"Dose reduction of preoperative radiotherapy in myxoid liposarcoma","volume":"7","author":"Lansu","year":"2021","journal-title":"JAMA Oncol"},{"issue":"1","key":"10.1016\/j.ejso.2022.09.008_bib26","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1245\/s10434-006-9043-7","article-title":"Clinicopathologic prognostic factors in myxoid liposarcoma: a retrospective study of 49 patients with long-term follow-up","volume":"14","author":"Heuvel","year":"2007","journal-title":"Ann Surg Oncol"},{"issue":"12","key":"10.1016\/j.ejso.2022.09.008_bib27","doi-asserted-by":"crossref","first-page":"2522","DOI":"10.1002\/cncr.22720","article-title":"Myxoid\/round cell and pleomorphic liposarcomas","volume":"109","author":"Fiore","year":"2007","journal-title":"Cancer"},{"issue":"4","key":"10.1016\/j.ejso.2022.09.008_bib28","doi-asserted-by":"crossref","first-page":"1081","DOI":"10.1245\/s10434-011-2127-z","article-title":"Myxoid\u2216Round cell liposarcoma (MRCLS) revisited: an analysis of 418 primarily managed cases","volume":"19","author":"Moreau","year":"2012","journal-title":"Ann Surg Oncol"},{"issue":"8","key":"10.1016\/j.ejso.2022.09.008_bib29","doi-asserted-by":"crossref","first-page":"1450","DOI":"10.1002\/(SICI)1097-0142(19960415)77:8<1450::AID-CNCR5>3.0.CO;2-G","article-title":"The clinicopathologic spectrum of myxoid and round cell liposarcoma: a study of 95 cases","volume":"77","author":"Kilpatrick","year":"1996","journal-title":"Cancer"},{"issue":"NA","key":"10.1016\/j.ejso.2022.09.008_bib30","first-page":"47","article-title":"Subtype specific prognostic nomogram for patients with primary liposarcoma of the retroperitoneum, extremity, or trunk","volume":"124","author":"Dalal","year":"2006","journal-title":"Transactions Meet Am Surg Assoc"},{"issue":"9","key":"10.1016\/j.ejso.2022.09.008_bib31","doi-asserted-by":"crossref","first-page":"2824","DOI":"10.1245\/s10434-015-4631-z","article-title":"The influence of time interval between preoperative radiation and surgical resection on the development of wound healing complications in extremity soft tissue sarcoma","volume":"22","author":"Griffin","year":"2015","journal-title":"Ann Surg Oncol"}],"container-title":["European Journal of Surgical Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S074879832200659X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S074879832200659X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T01:46:23Z","timestamp":1760060783000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S074879832200659X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,2]]},"references-count":31,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2023,2]]}},"alternative-id":["S074879832200659X"],"URL":"https:\/\/doi.org\/10.1016\/j.ejso.2022.09.008","relation":{},"ISSN":["0748-7983"],"issn-type":[{"value":"0748-7983","type":"print"}],"subject":[],"published":{"date-parts":[[2023,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Intermuscular extremity myxoid liposarcoma can be managed by marginal resection following neoadjuvant radiotherapy","name":"articletitle","label":"Article Title"},{"value":"European Journal of Surgical Oncology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ejso.2022.09.008","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}]}}