{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T17:24:59Z","timestamp":1793381099988,"version":"4.5.0"},"reference-count":44,"publisher":"Elsevier BV","issue":"10","license":[{"start":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T00:00:00Z","timestamp":1696118400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T00:00:00Z","timestamp":1696118400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,8,11]],"date-time":"2023-08-11T00:00:00Z","timestamp":1691712000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003761","name":"UMC Utrecht","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003761","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","ejso.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Surgical Oncology"],"published-print":{"date-parts":[[2023,10]]},"DOI":"10.1016\/j.ejso.2023.107017","type":"journal-article","created":{"date-parts":[[2023,8,14]],"date-time":"2023-08-14T11:45:07Z","timestamp":1692013507000},"page":"107017","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"title":["Impact of body composition and physical strength changes during chemoradiotherapy on complications and survival after oesophagectomy"],"prefix":"10.1016","volume":"49","author":[{"given":"R.B.","family":"den Boer","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I.L.","family":"Defize","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"W.","family":"Veldhuis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"Steenhagen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4266-3614","authenticated-orcid":false,"given":"A.","family":"Kerst","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"van Hillegersberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.A.","family":"de Jong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.P.","family":"Ruurda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ejso.2023.107017_bib1","series-title":"Treatments for esophageal cancer : a review","first-page":"330","author":"Kato","year":"2013"},{"key":"10.1016\/j.ejso.2023.107017_bib2","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1093\/ageing\/afac220","article-title":"Sarcopenia definition, diagnosis and treatment: consensus is growing","volume":"51","author":"Sayer","year":"2022","journal-title":"Age Ageing"},{"key":"10.1016\/j.ejso.2023.107017_bib3","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1016\/j.clnu.2011.08.008","article-title":"Marked changes in body composition following neoadjuvant chemotherapy for oesophagogastric cancer","volume":"31","author":"Awad","year":"2012","journal-title":"Clin Nutr"},{"key":"10.1016\/j.ejso.2023.107017_bib4","article-title":"Decrease of physical fitness during neoadjuvant chemoradiotherapy predicts the risk of pneumonia after esophagectomy","volume":"34","author":"Bor","year":"2021","journal-title":"Dis esophagus Off J Int Soc Dis Esophagus"},{"key":"10.1016\/j.ejso.2023.107017_bib5","first-page":"594","article-title":"Poor performance in incremental shuttle walk and cardiopulmonary exercise testing predicts poor overall survival for patients undergoing esophago-gastric resection","volume":"44","author":"Whibley","year":"2018","journal-title":"Eur J Surg Oncol J Eur Soc Surg Oncol Br Assoc Surg Oncol"},{"key":"10.1016\/j.ejso.2023.107017_bib6","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1016\/j.ejca.2015.12.030","article-title":"Prognostic value of sarcopenia in adults with solid tumours: a meta-analysis and systematic review","volume":"57","author":"Shachar","year":"2016","journal-title":"Eur J Cancer"},{"key":"10.1016\/j.ejso.2023.107017_bib7","doi-asserted-by":"crossref","DOI":"10.1016\/S0140-6736(19)31138-9","article-title":"Sarcopenia","volume":"393","author":"Cruz-jentoft","year":"2019","journal-title":"Lancet"},{"key":"10.1016\/j.ejso.2023.107017_bib8","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1007\/s11357-013-9556-5","article-title":"Diagnostic criteria for sarcopenia and physical performance","volume":"36","author":"Bijlsma","year":"2014","journal-title":"Age"},{"key":"10.1016\/j.ejso.2023.107017_bib9","first-page":"1781","article-title":"Severe sarcopenia might be associated with a decline of physical independence in older patients undergoing chemotherapeutic treatment","volume":"26","author":"Rier","year":"2018","journal-title":"Support Care Cancer"},{"key":"10.1016\/j.ejso.2023.107017_bib10","article-title":"Body composition assessment and sarcopenia in patients with gastric cancer : a systematic review and meta-analysis","author":"Kamarajah","year":"2018","journal-title":"Gastric Cancer"},{"key":"10.1016\/j.ejso.2023.107017_bib11","doi-asserted-by":"crossref","first-page":"716","DOI":"10.1016\/j.hpb.2019.09.010","article-title":"Exploring the relation between preoperative physical functioning and the impact of major complications in patients following pancreatic resection","volume":"22","author":"Van Beijsterveld","year":"2020","journal-title":"Hpb"},{"key":"10.1016\/j.ejso.2023.107017_bib12","doi-asserted-by":"crossref","first-page":"1760","DOI":"10.1016\/j.ejso.2018.08.011","article-title":"Better preoperative physical performance reduces the odds of complication severity and discharge to care facility after abdominal cancer resection in people over the age of 70 \u2013 a prospective cohort study","volume":"44","author":"Karlsson","year":"2018","journal-title":"Eur J Surg Oncol"},{"key":"10.1016\/j.ejso.2023.107017_bib13","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1016\/j.clnesp.2020.07.007","article-title":"Fat density is a novel prognostic marker in patients with esophageal cancer","volume":"39","author":"Anciaux","year":"2020","journal-title":"Clin Nutr ESPEN"},{"key":"10.1016\/j.ejso.2023.107017_bib14","doi-asserted-by":"crossref","DOI":"10.1016\/j.nut.2021.111534","article-title":"Body composition in relation to postoperative anastomotic leakage and overall survival in patients with esophageal cancer","volume":"94","author":"Li","year":"2022","journal-title":"Nutrition"},{"key":"10.1016\/j.ejso.2023.107017_bib15","volume":"vol. 34","author":"Blauwhoff-buskermolen","year":"2019"},{"key":"10.1016\/j.ejso.2023.107017_bib16","first-page":"458","author":"Rutten","year":"2016"},{"key":"10.1016\/j.ejso.2023.107017_bib17","doi-asserted-by":"crossref","DOI":"10.1007\/s00268-016-3603-1","article-title":"Sarcopenia\/muscle mass is not a prognostic factor for short- and long-term outcome after esophagectomy for cancer","author":"Grotenhuis","year":"2016","journal-title":"World J Surg"},{"key":"10.1016\/j.ejso.2023.107017_bib18","doi-asserted-by":"crossref","first-page":"3741","DOI":"10.1245\/s10434-017-6020-2","article-title":"Negative impact of skeletal muscle wasting after neoadjuvant chemotherapy followed by surgery on survival for patients with thoracic esophageal cancer","volume":"24","author":"Mayanagi","year":"2017","journal-title":"Ann Surg Oncol"},{"key":"10.1016\/j.ejso.2023.107017_bib19","doi-asserted-by":"crossref","first-page":"4745","DOI":"10.1016\/j.clnu.2021.03.031","article-title":"ESPEN practical guideline: clinical nutrition in surgery","volume":"40","author":"Weimann","year":"2021","journal-title":"Clin Nutr"},{"key":"10.1016\/j.ejso.2023.107017_bib20","doi-asserted-by":"crossref","first-page":"S645","DOI":"10.21037\/jtd.2018.11.33","article-title":"Preoperative nutritional optimization of esophageal cancer patients","volume":"11","author":"Steenhagen","year":"2019","journal-title":"J\u00a0Thorac Dis"},{"key":"10.1016\/j.ejso.2023.107017_bib21","first-page":"1","volume":"vol. 6","author":"Mullie","year":"2019"},{"key":"10.1016\/j.ejso.2023.107017_bib22","doi-asserted-by":"crossref","DOI":"10.1016\/S1470-2045(08)70153-0","article-title":"Prevalence and clinical implications of sarcopenic obesity in patients with solid tumours of the respiratory and gastrointestinal tracts: a population-based study","author":"Prado","year":"2008","journal-title":"Lancet Oncol"},{"key":"10.1016\/j.ejso.2023.107017_bib23","doi-asserted-by":"crossref","first-page":"678","DOI":"10.1002\/jso.24214","article-title":"Sarcopenia as a predictor of pulmonary complications after esophagectomy for thoracic esophageal cancer","volume":"113","author":"Nishigori","year":"2016","journal-title":"J\u00a0Surg Oncol"},{"key":"10.1016\/j.ejso.2023.107017_bib24","doi-asserted-by":"crossref","first-page":"724","DOI":"10.1016\/j.clnu.2015.05.011","article-title":"Sarcopenic obesity: a probable risk factor for dose limiting toxicity during neo-adjuvant chemotherapy in oesophageal cancer patients","volume":"35","author":"Anandavadivelan","year":"2016","journal-title":"Clin Nutr"},{"key":"10.1016\/j.ejso.2023.107017_bib25","doi-asserted-by":"crossref","first-page":"822","DOI":"10.1097\/SLA.0000000000002398","article-title":"Sarcopenia: prevalence, and impact on operative and oncologic outcomes in the multimodal management of locally advanced esophageal cancer","volume":"266","author":"Elliott","year":"2017","journal-title":"Ann Surg"},{"key":"10.1016\/j.ejso.2023.107017_bib26","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1589\/jpts.31.75","article-title":"Minimal clinically important difference for grip strength: a systematic review","volume":"31","author":"Bohannon","year":"2019","journal-title":"J\u00a0Phys Ther Sci"},{"key":"10.1016\/j.ejso.2023.107017_bib27","doi-asserted-by":"crossref","first-page":"2167","DOI":"10.1016\/j.apmr.2017.02.013","article-title":"Validation and refinement of prediction models to estimate exercise capacity in cancer survivors using the steep ramp test","volume":"98","author":"Stuiver","year":"2017","journal-title":"Arch Phys Med Rehabil"},{"key":"10.1016\/j.ejso.2023.107017_bib28","first-page":"187","volume":"vol. 250","author":"Clavien","year":"2009"},{"key":"10.1016\/j.ejso.2023.107017_bib29","first-page":"30","article-title":"Multiple imputation with multivariate imputation by chained equation (MICE) package","volume":"4","author":"Zhang","year":"2016","journal-title":"Ann Transl Med"},{"key":"10.1016\/j.ejso.2023.107017_bib30","doi-asserted-by":"crossref","first-page":"1090","DOI":"10.1016\/S1470-2045(15)00040-6","article-title":"Neoadjuvant chemoradiotherapy plus surgery versus surgery alone for oesophageal or junctional cancer (CROSS): long-term results of a randomised controlled trial","volume":"16","author":"Shapiro","year":"2015","journal-title":"Lancet Oncol"},{"key":"10.1016\/j.ejso.2023.107017_bib31","doi-asserted-by":"crossref","first-page":"1761","DOI":"10.1002\/jpen.2415","article-title":"Prevalence of sarcopenia in patients with solid tumors: a meta-analysis based on 81,814 patients","volume":"46","author":"Surov","year":"2022","journal-title":"JPEN - J Parenter Enter Nutr"},{"key":"10.1016\/j.ejso.2023.107017_bib32","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1016\/j.cger.2011.03.004","article-title":"The epidemiology of sarcopenia","volume":"27","author":"Janssen","year":"2011","journal-title":"Clin Geriatr Med"},{"key":"10.1016\/j.ejso.2023.107017_bib33","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1111\/j.1447-0594.2012.00851.x","article-title":"Sarcopenia in the elderly: basic and clinical issues","volume":"12","author":"Wang","year":"2012","journal-title":"Geriatr Gerontol Int"},{"key":"10.1016\/j.ejso.2023.107017_bib34","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1186\/s40200-017-0302-x","article-title":"Prevalence of sarcopenia in the world: a systematic review and meta- analysis of general population studies","volume":"16","author":"Shafiee","year":"2017","journal-title":"J\u00a0Diabetes Metab Disord"},{"key":"10.1016\/j.ejso.2023.107017_bib35","doi-asserted-by":"crossref","first-page":"1","DOI":"10.4172\/2329-9096.1000342","article-title":"Prevalence of sarcopenia in cancer patients : review and future directions","volume":"4","author":"Morishita","year":"2016","journal-title":"Int J Phys Med Rehabil"},{"key":"10.1016\/j.ejso.2023.107017_bib36","doi-asserted-by":"crossref","DOI":"10.1186\/s12957-018-1327-4","article-title":"Loss of skeletal muscle mass during neoadjuvant treatments correlates with worse prognosis in esophageal cancer: a retrospective cohort study","author":"J\u00e4rvinen","year":"2018","journal-title":"World J Surg Oncol"},{"key":"10.1016\/j.ejso.2023.107017_bib37","doi-asserted-by":"crossref","first-page":"4445","DOI":"10.1245\/s10434-015-4558-4","article-title":"Loss of skeletal muscle mass during neoadjuvant chemoradiotherapy predicts postoperative mortality in esophageal cancer surgery","volume":"22","author":"Reisinger","year":"2015","journal-title":"Ann Surg Oncol"},{"key":"10.1016\/j.ejso.2023.107017_bib38","doi-asserted-by":"crossref","unstructured":"Daly LE, N\u00ed Bhuachalla \u00c9b, Power DG, Cushen SJ, James K, Ryan AM, Ryan A Loss of skeletal muscle during systemic chemotherapy is prognostic of poor survival in patients with foregut cancer. https:\/\/doi.org\/10.1002\/jcsm.12267.","DOI":"10.1002\/jcsm.12267"},{"key":"10.1016\/j.ejso.2023.107017_bib39","first-page":"1313","article-title":"The effect of neoadjuvant chemotherapy on physical fitness and survival in patients undergoing oesophagogastric cancer surgery","volume":"40","author":"Jack","year":"2014","journal-title":"Eur J Surg Oncol J Eur Soc Surg Oncol Br Assoc Surg Oncol"},{"key":"10.1016\/j.ejso.2023.107017_bib40","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1308\/rcsann.2016.0135","article-title":"The impact of neoadjuvant chemotherapy on cardiopulmonary physical fitness in gastro-oesophageal adenocarcinoma","volume":"98","author":"Sinclair","year":"2016","journal-title":"Ann R Coll Surg Engl"},{"key":"10.1016\/j.ejso.2023.107017_bib41","doi-asserted-by":"crossref","first-page":"756","DOI":"10.1002\/jcsm.12540","article-title":"Influence of body composition and muscle strength on outcomes after multimodal oesophageal cancer treatment","volume":"11","author":"Hagens","year":"2020","journal-title":"J\u00a0Cachexia Sarcopenia Muscle"},{"key":"10.1016\/j.ejso.2023.107017_bib42","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1016\/j.ijsu.2018.03.030","article-title":"Neoadjuvant therapy reduces cardiopulmunary function in patients undegoing oesophagectomy","volume":"53","author":"Thomson","year":"2018","journal-title":"Int J Surg"},{"key":"10.1016\/j.ejso.2023.107017_bib43","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.clnu.2018.08.002","article-title":"GLIM criteria for the diagnosis of malnutrition \u2013 a consensus report from the global clinical nutrition community","volume":"38","author":"Cederholm","year":"2019","journal-title":"Clin Nutr"},{"key":"10.1016\/j.ejso.2023.107017_bib44","article-title":"The role of prehabilitation in modern esophagogastric cancer surgery: a comprehensive review","volume":"14","author":"Bausys","year":"2022","journal-title":"Cancers"}],"container-title":["European Journal of Surgical Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0748798323006558?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0748798323006558?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T01:48:21Z","timestamp":1760060901000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0748798323006558"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,10]]},"references-count":44,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2023,10]]}},"alternative-id":["S0748798323006558"],"URL":"https:\/\/doi.org\/10.1016\/j.ejso.2023.107017","relation":{},"ISSN":["0748-7983"],"issn-type":[{"value":"0748-7983","type":"print"}],"subject":[],"published":{"date-parts":[[2023,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Impact of body composition and physical strength changes during chemoradiotherapy on complications and survival after oesophagectomy","name":"articletitle","label":"Article Title"},{"value":"European Journal of Surgical Oncology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ejso.2023.107017","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 The Authors. Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}],"article-number":"107017"}}