{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,15]],"date-time":"2026-01-15T23:59:50Z","timestamp":1768521590978,"version":"3.49.0"},"reference-count":26,"publisher":"Elsevier BV","issue":"7","license":[{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100000054","name":"National Cancer Institute","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.es","clinicalkey.com.au","clinicalkey.com","ejso.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Surgical Oncology"],"published-print":{"date-parts":[[2024,7]]},"DOI":"10.1016\/j.ejso.2024.108399","type":"journal-article","created":{"date-parts":[[2024,5,10]],"date-time":"2024-05-10T03:07:28Z","timestamp":1715310448000},"page":"108399","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"title":["Incidence and survival outcomes of patients with high-grade appendicular bone sarcoma and isolated regional lymph node metastasis: A national cohort database study"],"prefix":"10.1016","volume":"50","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6992-3581","authenticated-orcid":false,"given":"Angad DS.","family":"Bedi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lotte R.","family":"van der Linden","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marcos R.","family":"Gonzalez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel","family":"Karczewski","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paul C.","family":"Jutte","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0681-9004","authenticated-orcid":false,"given":"Santiago A.","family":"Lozano-Calderon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ejso.2024.108399_bib1","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1016\/S1470-2045(09)70286-4","article-title":"Ewing's sarcoma","volume":"11","author":"Balamuth","year":"2010","journal-title":"Lancet Oncol"},{"key":"10.1016\/j.ejso.2024.108399_bib2","doi-asserted-by":"crossref","DOI":"10.1002\/pbc.28355","article-title":"Ewing sarcoma","volume":"68","author":"Eaton","year":"2021","journal-title":"Pediatr Blood Cancer"},{"key":"10.1016\/j.ejso.2024.108399_bib3","doi-asserted-by":"crossref","first-page":"2508","DOI":"10.1097\/CORR.0000000000000846","article-title":"Regional lymph node involvement is associated with poorer survivorship in patients with chondrosarcoma: a SEER analysis","volume":"477","author":"Wan","year":"2019","journal-title":"Clin Orthop Relat Res"},{"key":"10.1016\/j.ejso.2024.108399_bib4","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1634\/theoncologist.2007-0237","article-title":"The clinical approach towards chondrosarcoma","volume":"13","author":"Gelderblom","year":"2008","journal-title":"Oncol"},{"key":"10.1016\/j.ejso.2024.108399_bib5","first-page":"117","article-title":"Chondrosarcoma of bone","volume":"vol. 162","author":"Leddy","year":"2014"},{"key":"10.1016\/j.ejso.2024.108399_bib6","doi-asserted-by":"crossref","first-page":"360","DOI":"10.3390\/cancers14020360","article-title":"Metastatic progression of osteosarcomas: a review of current knowledge of environmental versus oncogenic drivers","volume":"14","author":"Odri","year":"2022","journal-title":"Cancers"},{"key":"10.1016\/j.ejso.2024.108399_bib7","doi-asserted-by":"crossref","first-page":"7","DOI":"10.3322\/caac.21708","article-title":"Cancer statistics, 2022. CA A","volume":"72","author":"Siegel","year":"2022","journal-title":"CA A Cancer J Clin"},{"key":"10.1016\/j.ejso.2024.108399_bib8","first-page":"2457","article-title":"Predictors of the survival of patients with chondrosarcoma of bone and metastatic disease at diagnosis","volume":"10","author":"Wang","year":"2019","journal-title":"J\u00a0Cancer"},{"key":"10.1016\/j.ejso.2024.108399_bib9","article-title":"Epidemiology and therapies for metastatic sarcoma","volume":"147","author":"Reed","year":"2013","journal-title":"Crit Econ Polit (Nouv Ser)"},{"key":"10.1016\/j.ejso.2024.108399_bib10","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/j.humpath.2007.04.022","article-title":"Lymphatics and bone","volume":"39","author":"Edwards","year":"2008","journal-title":"Hum Pathol"},{"key":"10.1016\/j.ejso.2024.108399_bib11","doi-asserted-by":"crossref","first-page":"812","DOI":"10.4161\/cc.5.8.2646","article-title":"Lymphatic or hematogenous dissemination: how does a metastatic tumor cell decide?","volume":"5","author":"Wong","year":"2006","journal-title":"Cell Cycle"},{"key":"10.1016\/j.ejso.2024.108399_bib12","doi-asserted-by":"crossref","first-page":"7022","DOI":"10.21037\/tcr-20-2187","article-title":"Regional lymph node involvement is associated with poorer survivorship in patients with upper extremity osteosarcoma than with lower extremity osteosarcoma: a SEER analysis","volume":"9","author":"Xie","year":"2020","journal-title":"Transl Cancer Res"},{"key":"10.1016\/j.ejso.2024.108399_bib13","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1002\/pbc.24053","article-title":"Clinical features and outcomes in patients with Ewing sarcoma and regional lymph node involvement","volume":"59","author":"Applebaum","year":"2012","journal-title":"Pediatr Blood Cancer"},{"key":"10.1016\/j.ejso.2024.108399_bib14","article-title":"Appendicular dedifferentiated chondrosarcoma: a management and survival study from the SEER database","volume":"37","author":"Gonzalez","year":"2022","journal-title":"J\u00a0Bone Oncol"},{"key":"10.1016\/j.ejso.2024.108399_bib15","doi-asserted-by":"crossref","first-page":"1722","DOI":"10.1001\/jamaoncol.2016.6905","article-title":"Using the national cancer database for outcomes research: a review","volume":"3","author":"Boffa","year":"2017","journal-title":"JAMA Oncol"},{"key":"10.1016\/j.ejso.2024.108399_bib16","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1186\/s43055-021-00618-7","article-title":"Diagnostic performance of PET\/CT in primary malignant bone tumors","volume":"52","author":"Abdella","year":"2021","journal-title":"Egypt J Radiol Nucl Med"},{"key":"10.1016\/j.ejso.2024.108399_bib17","doi-asserted-by":"crossref","DOI":"10.3892\/ol.2019.10101","article-title":"Diagnostic efficacy of PET\/CT in bone tumors","author":"Han","year":"2019","journal-title":"Oncol Lett"},{"key":"10.1016\/j.ejso.2024.108399_bib18","doi-asserted-by":"crossref","first-page":"93","DOI":"10.3322\/caac.21388","article-title":"The Eighth Edition AJCC Cancer Staging Manual: continuing to build a bridge from a population-based to a more \u201cpersonalized\u201d approach to cancer staging","volume":"67","author":"Amin","year":"2017","journal-title":"CA A Cancer J Clin"},{"key":"10.1016\/j.ejso.2024.108399_bib19","doi-asserted-by":"crossref","first-page":"1471","DOI":"10.1245\/s10434-010-0985-4","article-title":"The American Joint committee on cancer: the 7th edition of the AJCC cancer staging manual and the future of TNM","volume":"17","author":"Edge","year":"2010","journal-title":"Ann Surg Oncol"},{"key":"10.1016\/j.ejso.2024.108399_bib20","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1097\/01.blo.0000141660.05125.46","article-title":"Lymph node metastasis in soft tissue sarcoma in an extremity","author":"Riad","year":"2004","journal-title":"Clin Orthop Relat Res"},{"key":"10.1016\/j.ejso.2024.108399_bib21","doi-asserted-by":"crossref","first-page":"1679","DOI":"10.1200\/JCO.1996.14.5.1679","article-title":"Analysis of prognostic factors in 1,041 patients with localized soft tissue sarcomas of the extremities","volume":"14","author":"Pisters","year":"1996","journal-title":"J\u00a0Clin Oncol"},{"key":"10.1016\/j.ejso.2024.108399_bib22","doi-asserted-by":"crossref","first-page":"869","DOI":"10.1200\/JCO.1996.14.3.869","article-title":"Prognostic factors in adult patients with locally controlled soft tissue sarcoma. A study of 546 patients from the French Federation of Cancer Centers Sarcoma Group","volume":"14","author":"Coindre","year":"1996","journal-title":"J\u00a0Clin Oncol"},{"key":"10.1016\/j.ejso.2024.108399_bib23","doi-asserted-by":"crossref","first-page":"710","DOI":"10.1016\/S0959-8049(99)00287-7","article-title":"Surgical margins, local recurrence and metastasis in soft tissue sarcomas: 559 surgically-treated patients from the Scandinavian Sarcoma Group Register","volume":"36","author":"Trovik","year":"2000","journal-title":"Eur J Cancer"},{"key":"10.1016\/j.ejso.2024.108399_bib24","doi-asserted-by":"crossref","first-page":"5098","DOI":"10.1002\/cncr.33189","article-title":"Curability of patients with lymph node metastases from extremity soft-tissue sarcoma","volume":"126","author":"Basile","year":"2020","journal-title":"Cancer"},{"key":"10.1016\/j.ejso.2024.108399_bib25","doi-asserted-by":"crossref","first-page":"2473","DOI":"10.21873\/anticanres.15023","article-title":"What is the clinical impact of sending tissue for histopathology during surgery for known, diffuse metastatic disease to bone?","volume":"41","author":"Gusho","year":"2021","journal-title":"Anticancer Res"},{"key":"10.1016\/j.ejso.2024.108399_bib26","first-page":"249","article-title":"Surgical management of pelvic bone sarcoma with internal hemipelvectomy: oncologic and Functional outcomes","volume":"8","author":"Salunke","year":"2017","journal-title":"J\u00a0Clinical Orthop Trauma"}],"container-title":["European Journal of Surgical Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0748798324004517?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0748798324004517?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,6,29]],"date-time":"2024-06-29T23:55:28Z","timestamp":1719705328000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0748798324004517"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,7]]},"references-count":26,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2024,7]]}},"alternative-id":["S0748798324004517"],"URL":"https:\/\/doi.org\/10.1016\/j.ejso.2024.108399","relation":{},"ISSN":["0748-7983"],"issn-type":[{"value":"0748-7983","type":"print"}],"subject":[],"published":{"date-parts":[[2024,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Incidence and survival outcomes of patients with high-grade appendicular bone sarcoma and isolated regional lymph node metastasis: A national cohort database study","name":"articletitle","label":"Article Title"},{"value":"European Journal of Surgical Oncology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ejso.2024.108399","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier Ltd, BASO ~ The Association for Cancer Surgery, and the European Society of Surgical Oncology. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"108399"}}