{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T10:53:21Z","timestamp":1782816801486,"version":"3.54.5"},"reference-count":31,"publisher":"Elsevier BV","issue":"9","license":[{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.es","clinicalkey.com.au","clinicalkey.com","ejso.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Surgical Oncology"],"published-print":{"date-parts":[[2024,9]]},"DOI":"10.1016\/j.ejso.2024.108472","type":"journal-article","created":{"date-parts":[[2024,6,5]],"date-time":"2024-06-05T10:07:03Z","timestamp":1717582023000},"page":"108472","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":8,"title":["Oncologic outcomes of de-escalating axillary treatment in clinically node-positive breast cancer patients treated with neoadjuvant systemic therapy \u2013 A two center cohort study"],"prefix":"10.1016","volume":"50","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7211-5059","authenticated-orcid":false,"given":"Robert-Jan","family":"Schipper","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne","family":"de Bruijn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1866-7367","authenticated-orcid":false,"given":"Maurice J.C.","family":"van der Sangen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johanne G.","family":"Bloemen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ingrid","family":"van den Hoven","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9215-5250","authenticated-orcid":false,"given":"Ester E.M.","family":"Schepers","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Birgit E.P.","family":"Vriens","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thom","family":"Boerman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dorien C.","family":"Rijkaart","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Linda M.H.","family":"van de Winkel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christel","family":"Brouwer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-5973-3923","authenticated-orcid":false,"given":"Laurence J.C.","family":"van Warmerdam","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maaike P.M.","family":"Gielens","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rob M.G.","family":"van Bommel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yvonne E.","family":"van Riet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8041-2720","authenticated-orcid":false,"given":"Adri C.","family":"Voogd","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5837-5513","authenticated-orcid":false,"given":"Grard A.P.","family":"Nieuwenhuijzen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"15","key":"10.1016\/j.ejso.2024.108472_bib1","doi-asserted-by":"crossref","first-page":"1796","DOI":"10.1200\/JCO.2011.38.8595","article-title":"Definition and impact of pathologic complete response on prognosis after neoadjuvant chemotherapy in various intrinsic breast cancer subtypes","volume":"30","author":"von Minckwitz","year":"2012","journal-title":"J Clin Oncol"},{"issue":"5","key":"10.1016\/j.ejso.2024.108472_bib2","doi-asserted-by":"crossref","first-page":"e553","DOI":"10.1097\/SLA.0000000000004572","article-title":"A prospective, multicenter registry study to evaluate the clinical feasibility of targeted axillary dissection (TAD) in node-positive breast cancer patients","volume":"276","author":"Kuemmel","year":"2022","journal-title":"Ann Surg"},{"issue":"6","key":"10.1016\/j.ejso.2024.108472_bib3","doi-asserted-by":"crossref","DOI":"10.1001\/jamasurg.2021.0891","article-title":"Axillary pathologic complete response after neoadjuvant systemic therapy by breast cancer subtype in patients with initially clinically node-positive disease: a systematic review and meta-analysis","volume":"156","author":"Samiei","year":"2021","journal-title":"JAMA Surg"},{"issue":"4","key":"10.1016\/j.ejso.2024.108472_bib4","doi-asserted-by":"crossref","first-page":"694","DOI":"10.1097\/SLA.0000000000004356","article-title":"Diagnostic performance of noninvasive imaging for assessment of axillary response after neoadjuvant systemic therapy in clinically node-positive breast cancer: a systematic review and meta-analysis","volume":"273","author":"Samiei","year":"2021","journal-title":"Ann Surg"},{"key":"10.1016\/j.ejso.2024.108472_bib5","article-title":"Axillary response monitoring after neoadjuvant chemotherapy in breast cancer: can we avoid the morbidity of axillary treatment?","author":"Vugts","year":"2014","journal-title":"Ann Surg"},{"issue":"8","key":"10.1016\/j.ejso.2024.108472_bib6","doi-asserted-by":"crossref","first-page":"1226","DOI":"10.1002\/bjs.7073","article-title":"Marking the axilla with radioactive iodine seeds (MARI procedure) may reduce the need for axillary dissection after neoadjuvant chemotherapy for breast cancer","volume":"97","author":"Straver","year":"2010","journal-title":"Br J Surg"},{"issue":"9","key":"10.1016\/j.ejso.2024.108472_bib7","doi-asserted-by":"crossref","first-page":"1188","DOI":"10.1002\/bjs.10555","article-title":"Combined PET-CT and axillary lymph node marking with radioactive iodine seeds (MARI procedure) for tailored axillary treatment in node-positive breast cancer after neoadjuvant therapy","volume":"104","author":"Koolen","year":"2017","journal-title":"Br J Surg"},{"issue":"10","key":"10.1016\/j.ejso.2024.108472_bib8","doi-asserted-by":"crossref","first-page":"1072","DOI":"10.1200\/JCO.2015.64.0094","article-title":"Improved axillary evaluation following neoadjuvant therapy for patients with node-positive breast cancer using selective evaluation of clipped nodes: implementation of targeted axillary dissection","volume":"34","author":"Caudle","year":"2016","journal-title":"J Clin Oncol"},{"issue":"11","key":"10.1016\/j.ejso.2024.108472_bib9","doi-asserted-by":"crossref","first-page":"991","DOI":"10.1001\/jamasurg.2022.3907","article-title":"Diagnostic accuracy of radioactive iodine seed placement in the axilla with sentinel lymph node biopsy after neoadjuvant chemotherapy in node-positive breast cancer","volume":"157","author":"Simons","year":"2022","journal-title":"JAMA Surg"},{"issue":"1","key":"10.1016\/j.ejso.2024.108472_bib10","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1007\/s10549-022-06545-z","article-title":"Three-year follow-up of de-escalated axillary treatment after neoadjuvant systemic therapy in clinically node-positive breast cancer: the MARI-protocol","volume":"193","author":"van Loevezijn","year":"2022","journal-title":"Breast Cancer Res Treat"},{"issue":"4","key":"10.1016\/j.ejso.2024.108472_bib11","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1016\/j.jclinepi.2007.11.008","article-title":"The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement: guidelines for reporting observational studies","volume":"61","author":"von Elm","year":"2008","journal-title":"J Clin Epidemiol"},{"key":"10.1016\/j.ejso.2024.108472_bib12","article-title":"Marking axillary lymph nodes with radioactive iodine seeds for axillary staging after neoadjuvant systemic treatment in breast cancer patients: the MARI procedure","author":"Donker","year":"2014","journal-title":"Ann Surg"},{"issue":"5","key":"10.1016\/j.ejso.2024.108472_bib13","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1016\/j.clbc.2017.04.006","volume":"17","author":"van Nijnatten","year":"2017","journal-title":"Clin Breast Cancer"},{"issue":"8","key":"10.1016\/j.ejso.2024.108472_bib14","doi-asserted-by":"crossref","first-page":"1068","DOI":"10.1016\/S0959-8049(02)00748-7","article-title":"Reduction in the number of sentinel lymph node procedures by preoperative ultrasonography of the axilla in breast cancer","volume":"39","author":"Deurloo","year":"2003","journal-title":"Eur J Cancer"},{"issue":"4","key":"10.1016\/j.ejso.2024.108472_bib15","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1097\/AAP.0b013e3181e8a3bb","article-title":"Ultrasound guidance and peripheral nerve injury: is our vision as sharp as we think it is?","volume":"35","author":"Neal","year":"2010","journal-title":"Reg Anesth Pain Med"},{"issue":"18","key":"10.1016\/j.ejso.2024.108472_bib16","doi-asserted-by":"crossref","first-page":"3205","DOI":"10.1016\/j.ejca.2010.07.034","article-title":"Detection of extra-axillary lymph node involvement with FDG PET\/CT in patients with stage II-III breast cancer","volume":"46","author":"Aukema","year":"2010","journal-title":"Eur J Cancer"},{"issue":"8","key":"10.1016\/j.ejso.2024.108472_bib17","doi-asserted-by":"crossref","first-page":"807","DOI":"10.1001\/jamasurg.2023.1772","article-title":"Safety of targeted axillary dissection after neoadjuvant therapy in patients with node-positive breast cancer","volume":"158","author":"Kuemmel","year":"2023","journal-title":"JAMA Surg"},{"issue":"6","key":"10.1016\/j.ejso.2024.108472_bib18","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1038\/nrc1098","article-title":"The pathogenesis of cancer metastasis: the 'seed and soil' hypothesis revisited","volume":"3","author":"Fidler","year":"2003","journal-title":"Nat Rev Cancer"},{"key":"10.1016\/j.ejso.2024.108472_bib19","doi-asserted-by":"crossref","unstructured":"Mamounas TP. Loco-regional irradiation in patients with biopsy-proven axillary node involvement at presentation who become pathologically node-negative after neoadjuvant chemotherapy: primary outcomes of NRG Oncology\/NSABP B-51\/RTOG 1304. GS-02-07. Paper presented at: SABCS2023; san antionio.","DOI":"10.1158\/1538-7445.SABCS23-GS02-07"},{"key":"10.1016\/j.ejso.2024.108472_bib20","article-title":"Prognostic effect of nodal status before and after neoadjuvant chemotherapy in breast cancer: a Dutch population-based study","author":"de Wild","year":"2023","journal-title":"Breast Cancer Res Treat"},{"issue":"6","key":"10.1016\/j.ejso.2024.108472_bib21","doi-asserted-by":"crossref","first-page":"1512","DOI":"10.1245\/s10434-018-6404-y","article-title":"Major reduction in axillary lymph node dissections after neoadjuvant systemic therapy for node-positive breast cancer by combining PET\/CT and the MARI procedure","volume":"25","author":"van der Noordaa","year":"2018","journal-title":"Ann Surg Oncol"},{"issue":"2","key":"10.1016\/j.ejso.2024.108472_bib22","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1007\/s10549-013-2678-8","article-title":"Pre-chemotherapy 18F-FDG PET\/CT upstages nodal stage in stage II-III breast cancer patients treated with neoadjuvant chemotherapy","volume":"141","author":"Koolen","year":"2013","journal-title":"Breast Cancer Res Treat"},{"issue":"1","key":"10.1016\/j.ejso.2024.108472_bib23","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1186\/s13063-018-3021-9","article-title":"Tailored axillary surgery with or without axillary lymph node dissection followed by radiotherapy in patients with clinically node-positive breast cancer (TAXIS): study protocol for a multicenter, randomized phase-III trial","volume":"19","author":"Henke","year":"2018","journal-title":"Trials"},{"issue":"1","key":"10.1016\/j.ejso.2024.108472_bib24","doi-asserted-by":"crossref","first-page":"e59","DOI":"10.1016\/j.clbc.2021.07.011","article-title":"MINImal vs. MAXimal invasive axillary staging and treatment after neoadjuvant systemic therapy in node positive breast cancer: protocol of a Dutch multicenter registry study (MINIMAX)","volume":"22","author":"de Wild","year":"2022","journal-title":"Clin Breast Cancer"},{"issue":"8","key":"10.1016\/j.ejso.2024.108472_bib25","doi-asserted-by":"crossref","first-page":"1928","DOI":"10.1016\/j.ejso.2021.04.041","article-title":"Rate and predictors of nodal pathological complete response following neoadjuvant endocrine treatment in clinically biopsy-proven node-positive breast cancer patients","volume":"47","author":"Schipper","year":"2021","journal-title":"Eur J Surg Oncol"},{"issue":"12","key":"10.1016\/j.ejso.2024.108472_bib26","doi-asserted-by":"crossref","first-page":"4669","DOI":"10.1245\/s10434-020-08905-9","article-title":"Axillary response in patients undergoing neoadjuvant endocrine treatment for node-positive breast cancer: systematic literature review and NCDB analysis","volume":"27","author":"Stafford","year":"2020","journal-title":"Ann Surg Oncol"},{"issue":"12","key":"10.1016\/j.ejso.2024.108472_bib27","doi-asserted-by":"crossref","first-page":"4702","DOI":"10.1245\/s10434-020-08888-7","article-title":"How effective is neoadjuvant endocrine therapy (NET) in downstaging the axilla and achieving breast-conserving surgery?","volume":"27","author":"Montagna","year":"2020","journal-title":"Ann Surg Oncol"},{"key":"10.1016\/j.ejso.2024.108472_bib28","unstructured":"Alliance for Clinical Trials in Oncology. Comparison of Axillary Lymph Node DIssection With Axillary Radiation for Patients With Node-Positive Breast Cancer Treated with Chemotherapy (ALLIANCE A011202). . https:\/\/clinicaltrials.gov\/ct2\/show\/NCT01901094."},{"key":"10.1016\/j.ejso.2024.108472_bib29","unstructured":"ANTEC-study. https:\/\/classic.clinicaltrials.gov\/ct2\/show\/NCT04109079."},{"issue":"15_suppl","key":"10.1016\/j.ejso.2024.108472_bib30","doi-asserted-by":"crossref","DOI":"10.1200\/JCO.2019.37.15_suppl.TPS600","volume":"37","author":"Mamounas","year":"2019","journal-title":"J Clin Oncol"},{"issue":"19","key":"10.1016\/j.ejso.2024.108472_bib31","doi-asserted-by":"crossref","first-page":"1836","DOI":"10.1056\/NEJMoa1701830","article-title":"20-Year risks of breast-cancer recurrence after stopping endocrine therapy at 5 years","volume":"377","author":"Pan","year":"2017","journal-title":"N Engl J Med"}],"container-title":["European Journal of Surgical Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0748798324005249?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0748798324005249?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,1,19]],"date-time":"2025-01-19T19:20:02Z","timestamp":1737314402000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0748798324005249"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,9]]},"references-count":31,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2024,9]]}},"alternative-id":["S0748798324005249"],"URL":"https:\/\/doi.org\/10.1016\/j.ejso.2024.108472","relation":{},"ISSN":["0748-7983"],"issn-type":[{"value":"0748-7983","type":"print"}],"subject":[],"published":{"date-parts":[[2024,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Oncologic outcomes of de-escalating axillary treatment in clinically node-positive breast cancer patients treated with neoadjuvant systemic therapy \u2013 A two center cohort study","name":"articletitle","label":"Article Title"},{"value":"European Journal of Surgical Oncology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ejso.2024.108472","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier Ltd, BASO ~ The Association for Cancer Surgery, and the European Society of Surgical Oncology. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"108472"}}