{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,11]],"date-time":"2026-07-11T03:12:54Z","timestamp":1783739574920,"version":"3.55.0"},"reference-count":36,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","ejso.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Surgical Oncology"],"published-print":{"date-parts":[[2026,2]]},"DOI":"10.1016\/j.ejso.2025.111352","type":"journal-article","created":{"date-parts":[[2025,12,17]],"date-time":"2025-12-17T00:25:19Z","timestamp":1765931119000},"page":"111352","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Identifying chemotherapy benefits in high-risk patients with stage IB gastric cancer based on recurrence prediction value: A multicenter retrospective study"],"prefix":"10.1016","volume":"52","author":[{"given":"Qi-Chen","family":"He","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ze-Ning","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu-Bin","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chang-Yue","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu-Qin","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rong-Zhen","family":"Xie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-1101-4124","authenticated-orcid":false,"given":"Yong-Hong","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun-Hua","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4981-9933","authenticated-orcid":false,"given":"Xing-Qi","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wen-Wu","family":"Qiu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ji-Xun","family":"He","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jia-Bin","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qi-Yue","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Long-Long","family":"Cao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mi","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ru-Hong","family":"Tu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ping","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chao-Hui","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chang-Ming","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jian-Xian","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jian-Wei","family":"Xie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"3","key":"10.1016\/j.ejso.2025.111352_bib1","first-page":"209","article-title":"Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries","volume":"71","author":"Sung","year":"2021","journal-title":"CA Cancer J Clin"},{"issue":"6","key":"10.1016\/j.ejso.2025.111352_bib2","doi-asserted-by":"crossref","first-page":"1082","DOI":"10.1007\/s10120-022-01317-6","article-title":"A retrospective 5-year survival analysis of surgically resected gastric cancer cases from the Japanese gastric cancer association nationwide registry (2001-2013)","volume":"25","author":"Kakeji","year":"2022","journal-title":"Gastric Cancer"},{"issue":"2","key":"10.1016\/j.ejso.2025.111352_bib3","doi-asserted-by":"crossref","first-page":"69","DOI":"10.5230\/jgc.2011.11.2.69","article-title":"Clinicopathological features and surgical treatment of gastric cancer in South Korea: the results of 2009 nationwide survey on surgically treated gastric cancer patients","volume":"11","author":"Jeong","year":"2011","journal-title":"J Gastric Cancer"},{"issue":"1","key":"10.1016\/j.ejso.2025.111352_bib4","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s10120-020-01042-y","article-title":"Japanese gastric cancer treatment guidelines 2018 (5th edition)","volume":"24","year":"2021","journal-title":"Gastric Cancer"},{"issue":"3","key":"10.1016\/j.ejso.2025.111352_bib5","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1007\/s10120-017-0770-1","article-title":"Validation of the American joint committee on cancer (AJCC) 8th edition stage system for gastric cancer patients: a population-based analysis","volume":"21","author":"He","year":"2018","journal-title":"Gastric Cancer"},{"issue":"6","key":"10.1016\/j.ejso.2025.111352_bib6","doi-asserted-by":"crossref","first-page":"1110","DOI":"10.21037\/jgo.2019.10.04","article-title":"Survival outcomes of patients with pathological stage I gastric cancer using the competing risks survival method","volume":"10","author":"de Jesus","year":"2019","journal-title":"J Gastrointest Oncol"},{"issue":"1","key":"10.1016\/j.ejso.2025.111352_bib7","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1186\/s12885-017-3265-x","article-title":"Is adjuvant chemotherapy necessary in pT1N1 gastric cancer?","volume":"17","author":"Shin","year":"2017","journal-title":"BMC Cancer"},{"issue":"2","key":"10.1016\/j.ejso.2025.111352_bib8","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1007\/s10120-016-0601-9","article-title":"Proposal of a new stage grouping of gastric cancer for TNM classification: International gastric cancer association staging project","volume":"20","author":"Sano","year":"2017","journal-title":"Gastric Cancer"},{"issue":"11","key":"10.1016\/j.ejso.2025.111352_bib9","doi-asserted-by":"crossref","first-page":"1499","DOI":"10.1007\/s12094-019-02078-y","article-title":"Implication of lymph node staging in migration and different treatment strategies for stage T2N0M0 and T1N1M0 resected gastric cancer: a SEER population analysis","volume":"21","author":"Wang","year":"2019","journal-title":"Clin Transl Oncol"},{"issue":"1","key":"10.1016\/j.ejso.2025.111352_bib10","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1245\/s10434-018-6995-3","article-title":"Adjuvant therapy is associated with improved survival in pT1N1 gastric cancer in a heterogeneous Western patient population","volume":"26","author":"Hester","year":"2019","journal-title":"Ann Surg Oncol"},{"issue":"2","key":"10.1016\/j.ejso.2025.111352_bib11","doi-asserted-by":"crossref","first-page":"167","DOI":"10.6004\/jnccn.2022.0008","article-title":"Gastric cancer, version 2.2022, NCCN clinical practice guidelines in oncology","volume":"20","author":"Ajani","year":"2022","journal-title":"J Natl Compr Cancer Netw"},{"issue":"6","key":"10.1016\/j.ejso.2025.111352_bib12","doi-asserted-by":"crossref","first-page":"1616","DOI":"10.1245\/s10434-018-6434-5","article-title":"Adjuvant chemotherapy versus chemoradiotherapy versus surgery alone for early gastric cancer with one or two lymph node metastasis","volume":"25","author":"Kim","year":"2018","journal-title":"Ann Surg Oncol"},{"key":"10.1016\/j.ejso.2025.111352_bib13","article-title":"Association of survival with adjuvant chemotherapy in patients with stage IB gastric cancer: a multicentre, observational, cohort study","volume":"45","author":"Gao","year":"2024","journal-title":"Lancet Reg Health West Pac"},{"issue":"12","key":"10.1016\/j.ejso.2025.111352_bib14","doi-asserted-by":"crossref","first-page":"1495","DOI":"10.1016\/j.ijsu.2014.07.013","article-title":"The strengthening the reporting of observational studies in epidemiology (STROBE) statement: guidelines for reporting observational studies","volume":"12","author":"von Elm","year":"2014","journal-title":"Int J Surg"},{"issue":"3","key":"10.1016\/j.ejso.2025.111352_bib15","doi-asserted-by":"crossref","first-page":"624","DOI":"10.1007\/s10120-018-0896-9","article-title":"Perioperative risk calculator for distal gastrectomy predicts overall survival in patients with gastric cancer","volume":"22","author":"Takeuchi","year":"2019","journal-title":"Gastric Cancer"},{"issue":"2","key":"10.1016\/j.ejso.2025.111352_bib16","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1097\/SLA.0000000000001127","article-title":"Risk model for distal gastrectomy when treating gastric cancer on the basis of data from 33,917 Japanese patients collected using a nationwide web-based data entry system","volume":"262","author":"Kurita","year":"2015","journal-title":"Ann Surg"},{"issue":"2","key":"10.1016\/j.ejso.2025.111352_bib17","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1097\/SLA.0000000000000644","article-title":"A risk model for esophagectomy using data of 5354 patients included in a Japanese nationwide web-based database","volume":"260","author":"Takeuchi","year":"2014","journal-title":"Ann Surg"},{"issue":"1","key":"10.1016\/j.ejso.2025.111352_bib18","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1186\/s13059-019-1716-1","article-title":"A practical guide to methods controlling false discoveries in computational biology","volume":"20","author":"Korthauer","year":"2019","journal-title":"Genome Biol"},{"issue":"1","key":"10.1016\/j.ejso.2025.111352_bib19","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1002\/cac2.12516","article-title":"The Chinese society of clinical oncology (CSCO): Clinical guidelines for the diagnosis and treatment of gastric cancer","volume":"44","author":"Wang","year":"2023","journal-title":"Cancer Commun"},{"issue":"4","key":"10.1016\/j.ejso.2025.111352_bib20","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1007\/s10120-011-0051-3","article-title":"Clinicopathological analysis for recurrence of stage Ib gastric cancer (according to the second English edition of the Japanese classification of gastric carcinoma)","volume":"14","author":"Yokoyama","year":"2011","journal-title":"Gastric Cancer"},{"issue":"3\u20134","key":"10.1016\/j.ejso.2025.111352_bib21","first-page":"82","article-title":"Benefit of adjuvant chemoradiotherapy for gastric adenocarcinoma: a SEER population analysis","volume":"7","author":"Seyedin","year":"2014","journal-title":"Gastrointest Cancer Res"},{"issue":"9","key":"10.1016\/j.ejso.2025.111352_bib22","doi-asserted-by":"crossref","first-page":"2936","DOI":"10.1245\/s10434-016-5224-1","article-title":"Multimodality therapy improves survival in resected early stage gastric cancer in the United States","volume":"23","author":"Datta","year":"2016","journal-title":"Ann Surg Oncol"},{"issue":"2","key":"10.1016\/j.ejso.2025.111352_bib23","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1007\/s11605-011-1756-7","article-title":"Is there a role for surgery with adequate nodal evaluation alone in gastric adenocarcinoma?","volume":"16","author":"Dudeja","year":"2012","journal-title":"J Gastrointest Surg"},{"issue":"2","key":"10.1016\/j.ejso.2025.111352_bib24","doi-asserted-by":"crossref","first-page":"514","DOI":"10.1007\/s12032-013-0514-y","article-title":"Time-varying pattern of recurrence risk for gastric cancer patients","volume":"30","author":"Feng","year":"2013","journal-title":"Med Oncol"},{"issue":"1","key":"10.1016\/j.ejso.2025.111352_bib25","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1007\/s10120-015-0464-5","article-title":"Risk factors for selection of patients at high risk of recurrence or death after complete surgical resection in stage I gastric cancer","volume":"19","author":"Park","year":"2016","journal-title":"Gastric Cancer"},{"issue":"3","key":"10.1016\/j.ejso.2025.111352_bib26","doi-asserted-by":"crossref","first-page":"328","DOI":"10.5230\/jgc.2020.20.e30","article-title":"Prognostic factors in stage IB gastric cancer after surgical resection","volume":"20","author":"Yu","year":"2020","journal-title":"J Gastric Cancer"},{"issue":"8","key":"10.1016\/j.ejso.2025.111352_bib27","doi-asserted-by":"crossref","first-page":"771","DOI":"10.1007\/BF02574499","article-title":"Prognostic effect of lymph node micrometastasis in patients with histologically node-negative gastric cancer","volume":"9","author":"Yasuda","year":"2002","journal-title":"Ann Surg Oncol"},{"issue":"4","key":"10.1016\/j.ejso.2025.111352_bib28","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1016\/j.ejso.2008.05.004","article-title":"Lymph node micrometastasis in node negative early gastric cancer","volume":"35","author":"Kim","year":"2009","journal-title":"Eur J Surg Oncol"},{"issue":"4","key":"10.1016\/j.ejso.2025.111352_bib29","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1097\/00000658-199604000-00007","article-title":"Factors influencing postoperative morbidity, mortality, and survival after resection for hilar cholangiocarcinoma","volume":"223","author":"Su","year":"1996","journal-title":"Ann Surg"},{"issue":"1","key":"10.1016\/j.ejso.2025.111352_bib30","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1007\/BF02482964","article-title":"The prognostic significance of lymph node metastasis and intrapancreatic perineural invasion in pancreatic cancer after curative resection","volume":"29","author":"Ozaki","year":"1999","journal-title":"Surg Today"},{"issue":"8","key":"10.1016\/j.ejso.2025.111352_bib31","doi-asserted-by":"crossref","first-page":"2037","DOI":"10.1245\/s10434-010-1027-y","article-title":"Prognostic significance of perineural invasion in patients with gastric cancer who underwent curative resection","volume":"17","author":"Bilici","year":"2010","journal-title":"Ann Surg Oncol"},{"key":"10.1016\/j.ejso.2025.111352_bib32","doi-asserted-by":"crossref","first-page":"7601","DOI":"10.2147\/CMAR.S264582","article-title":"Perineural invasion and postoperative complications are independent predictors of early recurrence and survival following curative resection of gastric cancer","volume":"12","author":"Chen","year":"2020","journal-title":"Cancer Manag Res"},{"key":"10.1016\/j.ejso.2025.111352_bib33","series-title":"U.S. cancer statistics data visualizations tool, based on 2021 submission data","year":"1999"},{"issue":"10","key":"10.1016\/j.ejso.2025.111352_bib34","doi-asserted-by":"crossref","first-page":"656","DOI":"10.1038\/s41571-022-00672-8","article-title":"Is early-onset cancer an emerging global epidemic? Current evidence and future implications","volume":"19","author":"Ugai","year":"2022","journal-title":"Nat Rev Clin Oncol"},{"issue":"9","key":"10.1016\/j.ejso.2025.111352_bib35","doi-asserted-by":"crossref","first-page":"865","DOI":"10.1001\/jamasurg.2021.2380","article-title":"Characteristics of early-onset vs late-onset colorectal cancer: a review","volume":"156","author":"Zaborowski","year":"2021","journal-title":"JAMA Surg"},{"issue":"9","key":"10.1016\/j.ejso.2025.111352_bib36","doi-asserted-by":"crossref","first-page":"1470","DOI":"10.7150\/jca.82876","article-title":"Clinical characteristics and oncological outcomes of surgically treated early-onset gastric adenocarcinoma - a retrospective cohort study","volume":"14","author":"Rompen","year":"2023","journal-title":"J Cancer"}],"container-title":["European Journal of Surgical Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0748798325017809?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0748798325017809?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,7,11]],"date-time":"2026-07-11T02:27:51Z","timestamp":1783736871000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0748798325017809"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2]]},"references-count":36,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2026,2]]}},"alternative-id":["S0748798325017809"],"URL":"https:\/\/doi.org\/10.1016\/j.ejso.2025.111352","relation":{},"ISSN":["0748-7983"],"issn-type":[{"value":"0748-7983","type":"print"}],"subject":[],"published":{"date-parts":[[2026,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Identifying chemotherapy benefits in high-risk patients with stage IB gastric cancer based on recurrence prediction value: A multicenter retrospective study","name":"articletitle","label":"Article Title"},{"value":"European Journal of Surgical Oncology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ejso.2025.111352","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier Ltd, BASO ~ The Association for Cancer Surgery, and the European Society of Surgical Oncology. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"111352"}}