{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T04:06:13Z","timestamp":1789185973052,"version":"build-2803163510"},"reference-count":28,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100010711","name":"Cancer Foundation Finland","doi-asserted-by":"publisher","award":["WBS4708719"],"award-info":[{"award-number":["WBS4708719"]}],"id":[{"id":"10.13039\/501100010711","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100008376","name":"HUS Helsinki University Hospital","doi-asserted-by":"publisher","award":["TYH2020302"],"award-info":[{"award-number":["TYH2020302"]}],"id":[{"id":"10.13039\/100008376","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100008376","name":"HUS Helsinki University Hospital","doi-asserted-by":"publisher","award":["TYH2025146"],"award-info":[{"award-number":["TYH2025146"]}],"id":[{"id":"10.13039\/100008376","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","ejso.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Surgical Oncology"],"published-print":{"date-parts":[[2026,5]]},"DOI":"10.1016\/j.ejso.2026.111744","type":"journal-article","created":{"date-parts":[[2026,3,10]],"date-time":"2026-03-10T07:20:50Z","timestamp":1773127250000},"page":"111744","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Evolution of lymph node assessment in endometrial carcinoma: a cohort study within the 2025 European prognostic classification"],"prefix":"10.1016","volume":"52","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3467-7194","authenticated-orcid":false,"given":"Karoliina","family":"Aro","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annukka","family":"Pasanen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4366-5099","authenticated-orcid":false,"given":"Ralf","family":"B\u00fctzow","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mikko","family":"Loukovaara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ejso.2026.111744_bib1","doi-asserted-by":"crossref","first-page":"1707","DOI":"10.1093\/jnci\/djn397","article-title":"Systematic pelvic lymphadenectomy vs. no lymphadenectomy in early-stage endometrial carcinoma: randomized clinical trial","volume":"100","author":"Benedetti Panici","year":"2008","journal-title":"J Natl Cancer Inst"},{"key":"10.1016\/j.ejso.2026.111744_bib2","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/S0140-6736(08)61766-3","article-title":"Efficacy of systematic pelvic lymphadenectomy in endometrial cancer (MRC ASTEC trial): a randomised study","volume":"373","author":"Kitchener","year":"2009","journal-title":"Lancet"},{"key":"10.1016\/j.ejso.2026.111744_bib3","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1016\/j.ejca.2016.03.079","article-title":"Evaluation of models to predict lymph node metastasis in endometrial cancer: a multicentre study","volume":"61","author":"Koskas","year":"2016","journal-title":"Eur J Cancer"},{"key":"10.1016\/j.ejso.2026.111744_bib4","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1136\/ijgc-2020-002230","article-title":"ESGO\/ESTRO\/ESP guidelines for the management of patients with endometrial carcinoma","volume":"31","author":"Concin","year":"2021","journal-title":"Int J Gynecol Cancer"},{"key":"10.1016\/j.ejso.2026.111744_bib5","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1016\/j.ygyno.2017.12.017","article-title":"Sentinel lymph node biopsy in endometrial cancer\u2013feasibility, safety and lymphatic complications","volume":"148","author":"Geppert","year":"2018","journal-title":"Gynecol Oncol"},{"key":"10.1016\/j.ejso.2026.111744_bib6","doi-asserted-by":"crossref","first-page":"e423","DOI":"10.1016\/S1470-2045(25)00167-6","article-title":"ESGO\u2013ESTRO\u2013ESP guidelines for the management of patients with endometrial carcinoma: update 2025","volume":"26","author":"Concin","year":"2025","journal-title":"Lancet Oncol"},{"key":"10.1016\/j.ejso.2026.111744_bib7","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/j.ygyno.2018.02.021","article-title":"Lymphnode staging update in the American Joint Committee on Cancer 8th Edition cancer staging manual","volume":"150","author":"Olawaiye","year":"2018","journal-title":"Gynecol Oncol"},{"key":"10.1016\/j.ejso.2026.111744_bib8","doi-asserted-by":"crossref","first-page":"1465","DOI":"10.1097\/IGC.0000000000000801","article-title":"L1 cell adhesion molecule as a predictor of disease-specific survival and patterns of relapse in endometrial cancer","volume":"26","author":"Pasanen","year":"2016","journal-title":"Int J Gynecol Cancer"},{"key":"10.1016\/j.ejso.2026.111744_bib9","doi-asserted-by":"crossref","first-page":"1443","DOI":"10.1038\/s41379-020-0501-8","article-title":"Clinicopathological significance of deficient DNA mismatch repair and MLH1 promoter methylation in endometrioid endometrial carcinoma","volume":"33","author":"Pasanen","year":"2020","journal-title":"Mod Pathol"},{"key":"10.1016\/j.ejso.2026.111744_bib10","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1038\/bjc.2015.190","article-title":"A clinically applicable molecular-based classification for endometrial cancers","volume":"113","author":"Talhouk","year":"2015","journal-title":"Br J Cancer"},{"key":"10.1016\/j.ejso.2026.111744_bib11","doi-asserted-by":"crossref","first-page":"802","DOI":"10.1002\/cncr.30496","article-title":"Confirmation of ProMisE: a simple, genomics-based clinical classifier for endometrial cancer","volume":"123","author":"Talhouk","year":"2017","journal-title":"Cancer"},{"key":"10.1016\/j.ejso.2026.111744_bib12","doi-asserted-by":"crossref","first-page":"1180","DOI":"10.1093\/annonc\/mdy058","article-title":"Final validation of the ProMisE molecular classifier for endometrial carcinoma in a large population-based case series","volume":"29","author":"Kommoss","year":"2018","journal-title":"Ann Oncol"},{"key":"10.1016\/j.ejso.2026.111744_bib13","series-title":"International agency for research on cancer","article-title":"Female genital tumours","year":"2020"},{"key":"10.1016\/j.ejso.2026.111744_bib14","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1002\/path.5373","article-title":"Clinicopathological and molecular characterisation of 'multiple-classifier' endometrial carcinomas","volume":"250","author":"Le\u00f3n-Castillo","year":"2020","journal-title":"J Pathol"},{"key":"10.1016\/j.ejso.2026.111744_bib15","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1002\/path.5372","article-title":"Interpretation of somatic POLE mutations in endometrial carcinoma","volume":"250","author":"Le\u00f3n-Castillo","year":"2020","journal-title":"J Pathol"},{"key":"10.1016\/j.ejso.2026.111744_bib16","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1002\/ijgo.14923","article-title":"Endometrial Cancer Staging Subcommittee, FIGO Women's Committee. FIGO staging of endometrial cancer: 2023","volume":"162","author":"Berek","year":"2023","journal-title":"Int J Gynecol Obstet"},{"key":"10.1016\/j.ejso.2026.111744_bib17","doi-asserted-by":"crossref","first-page":"159","DOI":"10.2307\/2529310","article-title":"The measurement of observer agreement for categorical data","volume":"33","author":"Landis","year":"1977","journal-title":"Biometrics"},{"key":"10.1016\/j.ejso.2026.111744_bib18","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1016\/j.ygyno.2016.07.090","article-title":"Molecular classification of endometrial carcinoma on diagnostic specimens is highly concordant with final hysterectomy: earlier prognostic information to guide treatment","volume":"143","author":"Talhouk","year":"2016","journal-title":"Gynecol Oncol"},{"key":"10.1016\/j.ejso.2026.111744_bib19","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1016\/j.ygyno.2019.06.012","article-title":"Molecular classification of endometrial carcinoma applied to endometrial biopsy specimens: towards early personalized patient management","volume":"154","author":"Abdulfatah","year":"2019","journal-title":"Gynecol Oncol"},{"key":"10.1016\/j.ejso.2026.111744_bib20","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1016\/j.ygyno.2014.02.011","article-title":"Tumor size, depth of invasion, and histologic grade as prognostic factors of lymph node involvement in endometrial cancer: a SEER analysis","volume":"133","author":"Vargas","year":"2014","journal-title":"Gynecol Oncol"},{"key":"10.1016\/j.ejso.2026.111744_bib21","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1016\/j.ygyno.2012.11.025","article-title":"MRI, PET\/CT and ultrasound in the preoperative staging of endometrial cancer\u2014a multicenter prospective comparative study","volume":"128","author":"Antonsen","year":"2013","journal-title":"Gynecol Oncol"},{"key":"10.1016\/j.ejso.2026.111744_bib22","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1016\/S1470-2045(17)30068-2","article-title":"A comparison of sentinel lymph node biopsy to lymphadenectomy for endometrial cancer staging (FIRES trial): a multicentre, prospective, cohort study","volume":"18","author":"Rossi","year":"2017","journal-title":"Lancet Oncol"},{"key":"10.1016\/j.ejso.2026.111744_bib23","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1038\/nature12113","article-title":"The Cancer Genome Atlas Research Network. Integrated genomic characterization of endometrial carcinoma","volume":"497","author":"Kandoth","year":"2013","journal-title":"Nature"},{"key":"10.1016\/j.ejso.2026.111744_bib24","doi-asserted-by":"crossref","first-page":"1360","DOI":"10.1038\/s41416-023-02141-0","article-title":"Prognostic refinement of NSMP high-risk endometrial cancers using oestrogen receptor immunohistochemistry","volume":"128","author":"Vermij","year":"2023","journal-title":"Br J Cancer"},{"key":"10.1016\/j.ejso.2026.111744_bib25","doi-asserted-by":"crossref","first-page":"4215","DOI":"10.1158\/1078-0432.CCR-15-2878","article-title":"Improved risk assessment by integrating molecular and clinicopathological factors in early-stage endometrial cancer\u2014combined analysis of the PORTEC cohorts","volume":"22","author":"Stelloo","year":"2016","journal-title":"Clin Cancer Res"},{"key":"10.1016\/j.ejso.2026.111744_bib26","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.ygyno.2024.06.016","article-title":"The impact of estrogen receptor and L1 cell adhesion molecule expression on endometrial cancer outcome correlates with clinicopathological risk group and molecular subgroup","volume":"189","author":"Aro","year":"2024","journal-title":"Gynecol Oncol"},{"key":"10.1016\/j.ejso.2026.111744_bib27","doi-asserted-by":"crossref","first-page":"543.e1","DOI":"10.1016\/j.ajog.2008.04.043","article-title":"GATA3 expression in estrogen receptor \u03b1-negative endometrial carcinomas identifies aggressive tumors with high proliferation and poor patient survival","volume":"199","author":"Engelsen","year":"2008","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.ejso.2026.111744_bib28","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1016\/j.ygyno.2017.11.019","article-title":"The unrecognized burden of cardiovascular risk factors in women newly diagnosed with endometrial cancer: a prospective case control study","volume":"148","author":"Kitson","year":"2018","journal-title":"Gynecol Oncol"}],"container-title":["European Journal of Surgical Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S074879832600363X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S074879832600363X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T03:11:14Z","timestamp":1789182674000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S074879832600363X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5]]},"references-count":28,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2026,5]]}},"alternative-id":["S074879832600363X"],"URL":"https:\/\/doi.org\/10.1016\/j.ejso.2026.111744","relation":{},"ISSN":["0748-7983"],"issn-type":[{"value":"0748-7983","type":"print"}],"subject":[],"published":{"date-parts":[[2026,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Evolution of lymph node assessment in endometrial carcinoma: a cohort study within the 2025 European prognostic classification","name":"articletitle","label":"Article Title"},{"value":"European Journal of Surgical Oncology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ejso.2026.111744","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier Ltd, BASO ~ The Association for Cancer Surgery, and the European Society of Surgical Oncology. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"111744"}}