{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T00:33:02Z","timestamp":1761093182601,"version":"build-2065373602"},"reference-count":40,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2008,6,1]],"date-time":"2008-06-01T00:00:00Z","timestamp":1212278400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2008,6,1]],"date-time":"2008-06-01T00:00:00Z","timestamp":1212278400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2014,6,5]],"date-time":"2014-06-05T00:00:00Z","timestamp":1401926400000},"content-version":"vor","delay-in-days":2195,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","ejves.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Vascular and Endovascular Surgery"],"published-print":{"date-parts":[[2008,6]]},"DOI":"10.1016\/j.ejvs.2008.02.003","type":"journal-article","created":{"date-parts":[[2008,3,26]],"date-time":"2008-03-26T09:55:39Z","timestamp":1206525339000},"page":"644-651","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":21,"title":["Deferred Urgency Carotid Artery Stenting in Symptomatic Patients: Clinical Lessons and Biomarker Patterns from a Prospective Registry"],"prefix":"10.1016","volume":"35","author":[{"given":"C.","family":"Setacci","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"de Donato","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"Chisci","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.","family":"Setacci","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Stella","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"Faggioli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B.","family":"Reimers","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Cernetti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.J.","family":"Lopera Quijada","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B.","family":"Cappi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"Sangiorgi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ejvs.2008.02.003_bib1","doi-asserted-by":"crossref","first-page":"915","DOI":"10.1016\/S0140-6736(04)15785-1","article-title":"Endarterectomy for symptomatic carotid stenosis in relation to clinical subgroups and timing of surgery","volume":"363","author":"Rothwell","year":"2004","journal-title":"Lancet"},{"key":"10.1016\/j.ejvs.2008.02.003_bib2","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1016\/0741-5214(94)90018-3","article-title":"Early endarterectomy for severe carotid artery stenosis after a non-disabling stroke: results from the North American Symptomatic Carotid Endarterectomy Trial","volume":"20","author":"Gasecki","year":"1994","journal-title":"J Vasc Surg"},{"key":"10.1016\/j.ejvs.2008.02.003_bib3","doi-asserted-by":"crossref","first-page":"983","DOI":"10.1161\/01.STR.20.8.983","article-title":"Determinants of early recurrence of cerebral infarction. The Stroke DataBank","volume":"20","author":"Sacco","year":"1989","journal-title":"Stroke"},{"key":"10.1016\/j.ejvs.2008.02.003_bib4","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1016\/0741-5214(85)90191-0","article-title":"Carotid endarterectomy in the stroke patient: computerized axial tomography to determine timing","volume":"2","author":"Dosick","year":"1985","journal-title":"J Vasc Surg"},{"key":"10.1016\/j.ejvs.2008.02.003_bib5","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1097\/00000658-198601000-00014","article-title":"Emergency carotid endarterectomy for patients with acute carotid occlusion and profound neurological deficits","volume":"203","author":"Meyer","year":"1986","journal-title":"Ann Surg"},{"key":"10.1016\/j.ejvs.2008.02.003_bib6","doi-asserted-by":"crossref","first-page":"2563","DOI":"10.1161\/01.STR.28.12.2563","article-title":"Timing of carotid endarterectomy after stroke","volume":"28","author":"Pritz","year":"1997","journal-title":"Stroke"},{"key":"10.1016\/j.ejvs.2008.02.003_bib7","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1016\/S0741-5214(94)70118-0","article-title":"Carotid endarterectomy for unstable and compelling neurologic conditions: do results justify an aggressive approach?","volume":"19","author":"Gertler","year":"1994","journal-title":"J Vasc Surg"},{"key":"10.1016\/j.ejvs.2008.02.003_bib8","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1016\/j.jvs.2003.08.003","article-title":"Early carotid endarterectomy after acute stroke","volume":"39","author":"Paty","year":"2004","journal-title":"J Vasc Surg"},{"key":"10.1016\/j.ejvs.2008.02.003_bib9","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1056\/NEJM199901143400207","article-title":"Atherosclerosis \u2013 an inflammatory disease","volume":"340","author":"Ross","year":"1999","journal-title":"N Engl J Med"},{"key":"10.1016\/j.ejvs.2008.02.003_bib10","first-page":"1687","article-title":"Role of macrophage colony-stimulating factor in atherosclerosis: studies of osteopetrotic mice","volume":"150","author":"Qiao","year":"1997","journal-title":"Am J Pathol"},{"key":"10.1016\/j.ejvs.2008.02.003_bib11","doi-asserted-by":"crossref","first-page":"774","DOI":"10.1161\/01.STR.31.3.774","article-title":"The symptomatic carotid plaque","volume":"31","author":"Golledge","year":"2000","journal-title":"Stroke"},{"key":"10.1016\/j.ejvs.2008.02.003_bib12","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1056\/NEJM199108153250701","article-title":"North American Symptomatic Carotid Endarterectomy Trial (NASCET) Collaborators Beneficial effect of carotid endarterectomy in symptomatic patients with high-grade carotid stenosis","volume":"325","year":"1991","journal-title":"N Engl J Med"},{"key":"10.1016\/j.ejvs.2008.02.003_bib13","doi-asserted-by":"crossref","first-page":"1497","DOI":"10.1161\/01.STR.19.12.1497","article-title":"Modification of Rankin Scale: Recovery of motor function after stroke","volume":"19","author":"Bonita","year":"1988","journal-title":"Stroke"},{"key":"10.1016\/j.ejvs.2008.02.003_bib15","doi-asserted-by":"crossref","first-page":"1432","DOI":"10.1016\/S0140-6736(07)61448-2","article-title":"Early use of Existing Preventive Strategies for Stroke (EXPRESS) study. Effect of urgent treatment of transient ischaemic attack and minor stroke on early recurrent stroke (EXPRESS study): a prospective population-based sequential comparison","volume":"370","author":"Rothwell","year":"2007","journal-title":"Lancet"},{"key":"10.1016\/j.ejvs.2008.02.003_bib16","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1136\/bmj.37991.635266.44","article-title":"Population based study of early risk of stroke after transient ischaemic attack or minor stroke: implications for public education and organisation of services","volume":"328","author":"Coull","year":"2004","journal-title":"BMJ"},{"key":"10.1016\/j.ejvs.2008.02.003_bib17","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1016\/j.ejvs.2006.03.016","article-title":"Early carotid endarterectomy after ischemic stroke: the results of a prospective multicenter Italian study","volume":"32","author":"Sbarigia","year":"2006","journal-title":"Eur J Vasc Endovasc Surg"},{"author":"SPREAD","key":"10.1016\/j.ejvs.2008.02.003_bib18"},{"key":"10.1016\/j.ejvs.2008.02.003_bib19","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/j.ejvs.2006.09.019","article-title":"Does free cell area influence the outcome in carotid artery stenting?","volume":"33","author":"Bosiers","year":"2007","journal-title":"Eur J Vasc Endovasc Surg"},{"key":"10.1016\/j.ejvs.2008.02.003_bib20","doi-asserted-by":"crossref","first-page":"1781","DOI":"10.1161\/01.CIR.87.6.1781","article-title":"Lipid lowering and plaque regression: new insights into prevention of plaque disruption and clinical events in coronary disease","volume":"87","author":"Brown","year":"1993","journal-title":"Circulation"},{"key":"10.1016\/j.ejvs.2008.02.003_bib21","first-page":"173","article-title":"Chronic ulcerated plaques: new insight into the pathogenesis of acute coronary disease","volume":"6","author":"Frink","year":"1994","journal-title":"J Invasive Cardiol"},{"key":"10.1016\/j.ejvs.2008.02.003_bib22","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1161\/01.CIR.92.3.657","article-title":"Coronary plaque disruption","volume":"92","author":"Falk","year":"1995","journal-title":"Circulation"},{"key":"10.1016\/j.ejvs.2008.02.003_bib23","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/S0002-9149(97)00483-9","article-title":"Role of inflammation in the pathogenesis of unstable coronary artery disease","volume":"80","author":"Crea","year":"1997","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.ejvs.2008.02.003_bib24","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1002\/(SICI)1096-9896(199701)181:1<93::AID-PATH696>3.0.CO;2-H","article-title":"Association of coronary plaque rupture and atherosclerotic inflammation","volume":"181","author":"Boyle","year":"1997","journal-title":"J Pathol"},{"key":"10.1016\/j.ejvs.2008.02.003_bib25","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1161\/01.ATV.19.1.54","article-title":"Inflammation of the atherosclerotic plaque and shoulder of the plaque is a common and locally observed feature in unruptured plaques of femoral and coronary arteries","volume":"19","author":"Pasterkamp","year":"1999","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"10.1016\/j.ejvs.2008.02.003_bib26","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1056\/NEJM199901143400207","article-title":"Atherosclerosis: an inflammatory disease","volume":"340","author":"Ross","year":"1999","journal-title":"N Engl J Med"},{"key":"10.1016\/j.ejvs.2008.02.003_bib27","doi-asserted-by":"crossref","first-page":"2135","DOI":"10.1161\/01.CIR.100.21.2135","article-title":"Perturbation of T-cell repertoire in patients with unstable angina","volume":"100","author":"Liuzzo","year":"1999","journal-title":"Circulation"},{"key":"10.1016\/j.ejvs.2008.02.003_bib28","first-page":"796","article-title":"Inflammatory mechanisms in atherosclerosis: from laboratory evidence to clinical application","volume":"2","author":"Blake","year":"2001","journal-title":"It Heart J"},{"key":"10.1016\/j.ejvs.2008.02.003_bib29","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1016\/S0741-5214(96)70237-9","article-title":"Atherosclerotic plaque rupture in symptomatic carotid artery stenosis","volume":"23","author":"Carr","year":"1996","journal-title":"J Vasc Surg"},{"key":"10.1016\/j.ejvs.2008.02.003_bib30","doi-asserted-by":"crossref","first-page":"757","DOI":"10.1016\/S0039-6060(97)90084-2","article-title":"Activated inflammatory cells are associated with plaque rupture in carotid artery stenosis","volume":"122","author":"Carr","year":"1997","journal-title":"Surgery"},{"key":"10.1016\/j.ejvs.2008.02.003_bib31","doi-asserted-by":"crossref","first-page":"1845","DOI":"10.1001\/jama.292.15.1845","article-title":"Extracranial thrombotically active carotid plaque as a risk factor for ischemic stroke","volume":"292","author":"Spagnoli","year":"2004","journal-title":"JAMA"},{"key":"10.1016\/j.ejvs.2008.02.003_bib32","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1191\/1358863x02vm420ra","article-title":"The role of matrix metalloproteinases in vascular disease","volume":"7","author":"Loftus","year":"2002","journal-title":"Vasc Med"},{"key":"10.1016\/j.ejvs.2008.02.003_bib33","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1046\/j.1365-2168.2002.02099.x","article-title":"Matrix metalloproteinases and atherosclerotic plaque instability","volume":"89","author":"Loftus","year":"2002","journal-title":"Br J Surg"},{"key":"10.1016\/j.ejvs.2008.02.003_bib34","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/S0021-9150(03)00149-7","article-title":"Serum matrix metalloproteinase-3 and tissue inhibitor of metalloproteinases-1 as potential markers of carotid atherosclerosis in infraclinical hyperlipidemia","volume":"169","author":"Beaudeux","year":"2003","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.ejvs.2008.02.003_bib35","doi-asserted-by":"crossref","first-page":"1022","DOI":"10.1056\/NEJMoa003147","article-title":"Pregnancy associated plasma protein A as a marker of acute coronary syndromes","volume":"345","author":"Bayes-Genis","year":"2001","journal-title":"N Engl J Med"},{"key":"10.1016\/j.ejvs.2008.02.003_bib36","doi-asserted-by":"crossref","first-page":"2201","DOI":"10.1016\/j.jacc.2005.11.086","article-title":"Pregnancy-associated plasma protein-a is markedly expressed by monocyte-macrophage cells in vulnerable and ruptured carotid atherosclerotic plaques: a link between inflammation and cerebrovascular events","volume":"47","author":"Sangiorgi","year":"2006","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.ejvs.2008.02.003_bib37","doi-asserted-by":"crossref","first-page":"1210","DOI":"10.1067\/mva.2002.122888","article-title":"Pixel distribution analysis of B-mode ultrasound scan images predicts istologic features of atherosclerotic carotid plaque","volume":"35","author":"Lal","year":"2002","journal-title":"J Vasc Surg"},{"key":"10.1016\/j.ejvs.2008.02.003_bib38","first-page":"55","article-title":"Intravascular elastography: principles and potentials","volume":"2","author":"Cespedes","year":"1997","journal-title":"Semin Interv Cardiol"},{"key":"10.1016\/j.ejvs.2008.02.003_bib39","doi-asserted-by":"crossref","first-page":"2756","DOI":"10.1161\/01.ATV.19.11.2756","article-title":"The diagnostic accuracy of ex vivo MRI for human atherosclerotic plaque characterization","volume":"19","author":"Shinnar","year":"1999","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"10.1016\/j.ejvs.2008.02.003_bib40","doi-asserted-by":"crossref","first-page":"1447","DOI":"10.1016\/S0140-6736(96)91684-0","article-title":"Thermal detection of cellular infiltrates in living atherosclerotic plaques: possible implication for plaque rupture and thrombosis","volume":"347","author":"Casscells","year":"1996","journal-title":"Lancet"},{"key":"10.1016\/j.ejvs.2008.02.003_bib41","doi-asserted-by":"crossref","first-page":"1596","DOI":"10.1161\/01.CIR.0000012527.94843.BF","article-title":"In vivo temperature heterogeneity of atherosclerotic plaques is determined by plaque composition","volume":"105","author":"Verheye","year":"2002","journal-title":"Circulation"}],"container-title":["European Journal of Vascular and Endovascular Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1078588408001159?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1078588408001159?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T10:43:17Z","timestamp":1761043397000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1078588408001159"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,6]]},"references-count":40,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2008,6]]}},"alternative-id":["S1078588408001159"],"URL":"https:\/\/doi.org\/10.1016\/j.ejvs.2008.02.003","relation":{},"ISSN":["1078-5884"],"issn-type":[{"type":"print","value":"1078-5884"}],"subject":[],"published":{"date-parts":[[2008,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Deferred Urgency Carotid Artery Stenting in Symptomatic Patients: Clinical Lessons and Biomarker Patterns from a Prospective Registry","name":"articletitle","label":"Article Title"},{"value":"European Journal of Vascular and Endovascular Surgery","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ejvs.2008.02.003","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2008 European Society for Vascular Surgery. Published by Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}