{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T09:22:15Z","timestamp":1790414535316,"version":"4.1.0"},"reference-count":51,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2014,8,1]],"date-time":"2014-08-01T00:00:00Z","timestamp":1406851200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2014,8,1]],"date-time":"2014-08-01T00:00:00Z","timestamp":1406851200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2014,6,20]],"date-time":"2014-06-20T00:00:00Z","timestamp":1403222400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","ejves.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Vascular and Endovascular Surgery"],"published-print":{"date-parts":[[2014,8]]},"DOI":"10.1016\/j.ejvs.2014.04.019","type":"journal-article","created":{"date-parts":[[2014,6,10]],"date-time":"2014-06-10T08:32:12Z","timestamp":1402389132000},"page":"169-184","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":49,"title":["Editor's Choice \u2013 The Effect of Supervision on Walking Distance in Patients with Intermittent Claudication: A Meta-analysis"],"prefix":"10.1016","volume":"48","author":[{"given":"L.N.M.","family":"Gommans","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Saarloos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.R.M.","family":"Scheltinga","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Houterman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.A.","family":"de Bie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.J.P.","family":"Fokkenrood","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.A.W.","family":"Teijink","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ejvs.2014.04.019_bib1","doi-asserted-by":"crossref","first-page":"1329","DOI":"10.1016\/S0140-6736(13)61249-0","article-title":"Comparison of global estimates of prevalence and risk factors for peripheral artery disease in 2000 and 2010: a systematic review and analysis","volume":"382","author":"Fowkes","year":"2013","journal-title":"Lancet"},{"issue":"Suppl. S","key":"10.1016\/j.ejvs.2014.04.019_bib2","doi-asserted-by":"crossref","first-page":"S5","DOI":"10.1016\/j.jvs.2006.12.037","article-title":"Inter-society consensus for the management of peripheral arterial disease (TASC II)","volume":"45","author":"Norgren","year":"2007","journal-title":"J\u00a0Vasc Surg"},{"key":"10.1016\/j.ejvs.2014.04.019_bib3","doi-asserted-by":"crossref","first-page":"1239","DOI":"10.1016\/j.jacc.2005.10.009","volume":"47","author":"Hirsch","year":"2006","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.ejvs.2014.04.019_bib4","doi-asserted-by":"crossref","first-page":"257","DOI":"10.2147\/JMDH.S35779","article-title":"Multidisciplinary treatment for peripheral arterial occlusive disease and the role of eHealth and mHealth","volume":"5","author":"Fokkenrood","year":"2012","journal-title":"J\u00a0Multidiscip Healthc"},{"key":"10.1016\/j.ejvs.2014.04.019_bib5","doi-asserted-by":"crossref","first-page":"495","DOI":"10.2147\/VHRM.S34095","article-title":"The ClaudicatioNet concept: design of a national integrated care network providing active and healthy aging for patients with intermittent claudication","volume":"8","author":"Lauret","year":"2012","journal-title":"Vasc Health Risk Manag"},{"key":"10.1016\/j.ejvs.2014.04.019_bib6","doi-asserted-by":"crossref","first-page":"1941","DOI":"10.1056\/NEJMra021135","article-title":"Exercise training for claudication","volume":"347","author":"Stewart","year":"2002","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.ejvs.2014.04.019_bib7","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1016\/j.jvs.2008.09.042","article-title":"Supervised exercise therapy for intermittent claudication in daily practice","volume":"49","author":"Kruidenier","year":"2009","journal-title":"J\u00a0Vasc Surg"},{"key":"10.1016\/j.ejvs.2014.04.019_bib8","doi-asserted-by":"crossref","first-page":"1192","DOI":"10.1016\/j.jvs.2007.01.059","article-title":"Supervised exercise therapy for intermittent claudication in a community-based setting is as effective as clinic-based","volume":"45","author":"Bendermacher","year":"2007","journal-title":"J\u00a0Vasc Surg"},{"key":"10.1016\/j.ejvs.2014.04.019_bib9","doi-asserted-by":"crossref","first-page":"2174","DOI":"10.2337\/dc10-2399","article-title":"Effects of a home-based walking intervention on mobility and quality of life in people with diabetes and peripheral arterial disease: a randomized controlled trial","volume":"34","author":"Collins","year":"2011","journal-title":"Diabetes Care"},{"key":"10.1016\/j.ejvs.2014.04.019_bib10","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1177\/000331979704800402","article-title":"Hospital vs home-based exercise rehabilitation for patients with peripheral arterial occlusive disease","volume":"48","author":"Regensteiner","year":"1997","journal-title":"Angiology"},{"key":"10.1016\/j.ejvs.2014.04.019_bib11","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1161\/CIRCULATIONAHA.110.963066","article-title":"Efficacy of quantified home-based exercise and supervised exercise in patients with intermittent claudication: a randomized controlled trial","volume":"123","author":"Gardner","year":"2011","journal-title":"Circulation"},{"key":"10.1016\/j.ejvs.2014.04.019_bib12","first-page":"CD005263","article-title":"Supervised exercise therapy versus non-supervised exercise therapy for intermittent claudication","author":"Bendermacher","year":"2006","journal-title":"Cochrane Database Syst Rev"},{"key":"10.1016\/j.ejvs.2014.04.019_bib13","doi-asserted-by":"crossref","first-page":"1132","DOI":"10.1016\/j.jvs.2012.04.046","article-title":"Supervised walking therapy in patients with intermittent claudication","volume":"56","author":"Fakhry","year":"2012","journal-title":"J\u00a0Vasc Surg"},{"key":"10.1016\/j.ejvs.2014.04.019_bib14","first-page":"CD000990","article-title":"Exercise for intermittent claudication","author":"Watson","year":"2008","journal-title":"Cochrane Database Syst Rev"},{"key":"10.1016\/j.ejvs.2014.04.019_bib15","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.ejvs.2006.12.030","article-title":"Exercise therapy and the additional effect of supervision on exercise therapy in patients with intermittent claudication. Systematic review of randomised controlled trials","volume":"34","author":"Wind","year":"2007","journal-title":"Eur J Vasc Endovasc Surg"},{"key":"10.1016\/j.ejvs.2014.04.019_bib16","first-page":"CD005263","article-title":"Supervised exercise therapy versus non-supervised exercise therapy for intermittent claudication","volume":"8","author":"Fokkenrood","year":"2013","journal-title":"Cochrane Database Syst Rev"},{"key":"10.1016\/j.ejvs.2014.04.019_bib17","doi-asserted-by":"crossref","DOI":"10.1002\/9780470712184","article-title":"Cochrane handbook for systematic reviews of interventions","author":"Higgins","year":"2008"},{"key":"10.1016\/j.ejvs.2014.04.019_bib18","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/0197-2456(86)90046-2","article-title":"Meta-analysis in clinical trials","volume":"7","author":"DerSimonian","year":"1986","journal-title":"Control Clin Trials"},{"key":"10.1016\/j.ejvs.2014.04.019_bib19","doi-asserted-by":"crossref","first-page":"1663","DOI":"10.1002\/sim.1752","article-title":"Controlling the risk of spurious findings from meta-regression","volume":"23","author":"Higgins","year":"2004","journal-title":"Stat Med"},{"key":"10.1016\/j.ejvs.2014.04.019_bib20","series-title":"Introduction to meta-analysis","author":"Borenstein","year":"2008"},{"key":"10.1016\/j.ejvs.2014.04.019_bib21","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/j.jvs.2005.09.013","article-title":"The constitutive procoagulant and hypofibrinolytic state in patients with intermittent claudication due to infrainguinal disease significantly improves with percutaneous transluminal balloon angioplasty","volume":"43","author":"Hobbs","year":"2006","journal-title":"J\u00a0Vasc Surg"},{"key":"10.1016\/j.ejvs.2014.04.019_bib22","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1177\/1538574408314442","article-title":"Local versus systemic mechanisms underlying supervised exercise training for intermittent claudication","volume":"42","author":"Stewart","year":"2008","journal-title":"Vasc Endovascular Surg"},{"key":"10.1016\/j.ejvs.2014.04.019_bib23","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1016\/j.jvs.2010.02.022","article-title":"Multicenter randomized clinical trial of supervised exercise therapy with or without feedback versus walking advice for intermittent claudication","volume":"52","author":"Nicolai","year":"2010","journal-title":"J\u00a0Vasc Surg"},{"key":"10.1016\/j.ejvs.2014.04.019_bib24","doi-asserted-by":"crossref","first-page":"1346","DOI":"10.1016\/j.jvs.2011.11.123","article-title":"Optimal exercise program length for patients with claudication","volume":"55","author":"Gardner","year":"2012","journal-title":"J\u00a0Vasc Surg"},{"key":"10.1016\/j.ejvs.2014.04.019_bib25","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1016\/S0741-5214(97)70352-5","article-title":"Value of a supervised exercise program for the therapy of arterial claudication","volume":"25","author":"Patterson","year":"1997","journal-title":"J\u00a0Vasc Surg"},{"key":"10.1016\/j.ejvs.2014.04.019_bib26","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1111\/j.1475-097X.2007.00770.x","article-title":"Randomized controlled trial of supervised exercise to evaluate changes in cardiac function in patients with peripheral atherosclerotic disease","volume":"28","author":"Hodges","year":"2008","journal-title":"Clin Physiol Funct Imaging"},{"key":"10.1016\/j.ejvs.2014.04.019_bib27","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1016\/j.atherosclerosis.2011.03.018","article-title":"Exercise training increases endothelial progenitor cells and decreases asymmetric dimethylarginine in peripheral arterial disease: a randomized controlled trial","volume":"217","author":"Schlager","year":"2011","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.ejvs.2014.04.019_bib28","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/j.jvs.2006.03.037","article-title":"Short-term effects of cycle and treadmill training on exercise tolerance in peripheral arterial disease","volume":"44","author":"Sanderson","year":"2006","journal-title":"J\u00a0Vasc Surg"},{"key":"10.1016\/j.ejvs.2014.04.019_bib29","first-page":"800","article-title":"Peripheral arterial disease and intermittent claudication: efficacy of short-term upper body strength training, dynamic exercise training, and advice to exercise at home","volume":"99","author":"Parr","year":"2009","journal-title":"S\u00a0Afr Med J"},{"key":"10.1016\/j.ejvs.2014.04.019_bib30","doi-asserted-by":"crossref","first-page":"754","DOI":"10.1177\/1741826710389421","article-title":"The effect of pain-free treadmill training on fibrinogen, haematocrit, and lipid profile in patients with claudication","volume":"18","author":"Mika","year":"2011","journal-title":"Eur J Cardiovasc Prev Rehabil"},{"key":"10.1016\/j.ejvs.2014.04.019_bib31","doi-asserted-by":"crossref","first-page":"225","DOI":"10.2147\/VHRM.S30056","article-title":"Effects of a 6-month exercise program pilot study on walking economy, peak physiological characteristics, and walking performance in patients with peripheral arterial disease","volume":"8","author":"Crowther","year":"2012","journal-title":"Vasc Health Risk Manag"},{"key":"10.1016\/j.ejvs.2014.04.019_bib32","series-title":"Statistical power analysis in the behavioral sciences","author":"Cohen","year":"1988"},{"key":"10.1016\/j.ejvs.2014.04.019_bib33","doi-asserted-by":"crossref","first-page":"e4947","DOI":"10.1136\/bmj.e4947","article-title":"Diagnosis and management of lower limb peripheral arterial disease: summary of NICE guidance","volume":"345","author":"Layden","year":"2012","journal-title":"BMJ"},{"key":"10.1016\/j.ejvs.2014.04.019_bib34","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1046\/j.1532-5415.2001.49152.x","article-title":"Exercise rehabilitation improves functional outcomes and peripheral circulation in patients with intermittent claudication: a randomized controlled trial","volume":"49","author":"Gardner","year":"2001","journal-title":"J\u00a0Am Geriatr Soc"},{"key":"10.1016\/j.ejvs.2014.04.019_bib35","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1016\/j.ejvs.2012.09.009","article-title":"Availability of supervised exercise programs and the role of structured home-based exercise in peripheral arterial disease","volume":"44","author":"Makris","year":"2012","journal-title":"Eur J Vasc Endovasc Surg"},{"key":"10.1016\/j.ejvs.2014.04.019_bib36","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1308\/003588409X432149","article-title":"Supervised exercise for intermittent claudication - an under-utilised tool","volume":"91","author":"Shalhoub","year":"2009","journal-title":"Ann R Coll Surg Engl"},{"key":"10.1016\/j.ejvs.2014.04.019_bib37","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1016\/j.ejvs.2013.12.021","article-title":"A\u00a0randomised controlled trial of supervised exercise regimens and their impact on walking performance, skeletal muscle mass and calpain activity in patients with intermittent claudication","volume":"47","author":"Delaney","year":"2014","journal-title":"Eur J Vasc Endovasc Surg"},{"key":"10.1016\/j.ejvs.2014.04.019_bib38","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1177\/1358863X08101858","article-title":"Efficacy of arm-ergometry versus treadmill exercise training to improve walking distance in patients with claudication","volume":"14","author":"Treat-Jacobson","year":"2009","journal-title":"Vasc Med"},{"key":"10.1016\/j.ejvs.2014.04.019_bib39","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1097\/00008483-200105000-00006","article-title":"Effects of home versus supervised exercise for patients with intermittent claudication","volume":"21","author":"Savage","year":"2001","journal-title":"J\u00a0Cardiopulm Rehabil"},{"key":"10.1016\/j.ejvs.2014.04.019_bib40","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/j.ejvs.2003.09.012","article-title":"Does supervised exercise offer adjuvant benefit over exercise advice alone for the treatment of intermittent claudication? A randomised trial","volume":"27","author":"Cheetham","year":"2004","journal-title":"Eur J Vasc Endovasc Surg"},{"key":"10.1016\/j.ejvs.2014.04.019_bib41","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1016\/j.ejvs.2005.03.011","article-title":"Improvement of the walking ability in intermittent claudication due to superficial femoral artery occlusion with supervised exercise and pneumatic foot and calf compression: a randomised controlled trial","volume":"30","author":"Kakkos","year":"2005","journal-title":"Eur J Vasc Endovasc Surg"},{"key":"10.1016\/j.ejvs.2014.04.019_bib42","doi-asserted-by":"crossref","first-page":"602","DOI":"10.1161\/01.CIR.81.2.602","article-title":"Benefit of exercise conditioning for patients with peripheral arterial disease","volume":"81","author":"Hiatt","year":"1990","journal-title":"Circulation"},{"key":"10.1016\/j.ejvs.2014.04.019_bib43","doi-asserted-by":"crossref","first-page":"1866","DOI":"10.1161\/01.CIR.90.4.1866","article-title":"Superiority of treadmill walking exercise versus strength training for patients with peripheral arterial disease. Implications for the mechanism of the training response","volume":"90","author":"Hiatt","year":"1994","journal-title":"Circulation"},{"key":"10.1016\/j.ejvs.2014.04.019_bib44","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/j.jvs.2006.08.084","article-title":"The effect of supervised exercise and cilostazol on coagulation and fibrinolysis in intermittent claudication: a randomized controlled trial","volume":"45","author":"Hobbs","year":"2007","journal-title":"J\u00a0Vasc Surg"},{"key":"10.1016\/j.ejvs.2014.04.019_bib45","first-page":"8","article-title":"Peripheral arterial insufficiency, effect of physical training on walking tolerance, calf blood flow, and blood flow resistance","author":"Dahllof","year":"1976","journal-title":"Scand J Rehabil Med"},{"key":"10.1016\/j.ejvs.2014.04.019_bib46","doi-asserted-by":"crossref","first-page":"448","DOI":"10.1046\/j.1365-2796.2002.01055.x","article-title":"The effects of exercise training on walking function and perception of health status in elderly patients with peripheral arterial occlusive disease","volume":"252","author":"Tsai","year":"2002","journal-title":"J\u00a0Intern Med"},{"key":"10.1016\/j.ejvs.2014.04.019_bib47","doi-asserted-by":"crossref","first-page":"887","DOI":"10.1067\/mva.2002.123756","article-title":"Increasing exercise tolerance of persons limited by claudication pain using polestriding","volume":"35","author":"Langbein","year":"2002","journal-title":"J\u00a0Vasc Surg"},{"key":"10.1016\/j.ejvs.2014.04.019_bib48","doi-asserted-by":"crossref","first-page":"756","DOI":"10.1097\/01.phm.0000176346.94747.49","article-title":"Experimental model of pain-free treadmill training in patients with claudication","volume":"84","author":"Mika","year":"2005","journal-title":"Am J Phys Med Rehabil"},{"key":"10.1016\/j.ejvs.2014.04.019_bib49","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1097\/00042752-200607000-00009","article-title":"Red blood cell deformability in patients with claudication after pain-free treadmill training","volume":"16","author":"Mika","year":"2006","journal-title":"Clin J Sport Med"},{"key":"10.1016\/j.ejvs.2014.04.019_bib50","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1042\/CS20060151","article-title":"Effect of training on the response of plasma vascular endothelial growth factor to exercise in patients with peripheral arterial disease","volume":"111","author":"Wood","year":"2006","journal-title":"Clin Sci (Lond)"},{"key":"10.1016\/j.ejvs.2014.04.019_bib51","doi-asserted-by":"crossref","first-page":"w13623","DOI":"10.4414\/smw.2012.13623","article-title":"Impact of exercise training on inflammation and platelet activation in patients with intermittent claudication","volume":"142","author":"Schlager","year":"2012","journal-title":"Swiss Med Wkly"}],"container-title":["European Journal of Vascular and Endovascular Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1078588414002068?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1078588414002068?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T11:40:35Z","timestamp":1761046835000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1078588414002068"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,8]]},"references-count":51,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2014,8]]}},"alternative-id":["S1078588414002068"],"URL":"https:\/\/doi.org\/10.1016\/j.ejvs.2014.04.019","relation":{},"ISSN":["1078-5884"],"issn-type":[{"value":"1078-5884","type":"print"}],"subject":[],"published":{"date-parts":[[2014,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Editor's Choice \u2013 The Effect of Supervision on Walking Distance in Patients with Intermittent Claudication: A Meta-analysis","name":"articletitle","label":"Article Title"},{"value":"European Journal of Vascular and Endovascular Surgery","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ejvs.2014.04.019","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2014 European Society for Vascular Surgery. Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}]}}