{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T08:03:32Z","timestamp":1792569812709,"version":"4.5.0"},"reference-count":35,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2020,10,1]],"date-time":"2020-10-01T00:00:00Z","timestamp":1601510400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,10,1]],"date-time":"2020-10-01T00:00:00Z","timestamp":1601510400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T00:00:00Z","timestamp":1633046400000},"content-version":"vor","delay-in-days":365,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","ejves.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Vascular and Endovascular Surgery"],"published-print":{"date-parts":[[2020,10]]},"DOI":"10.1016\/j.ejvs.2020.05.037","type":"journal-article","created":{"date-parts":[[2020,7,21]],"date-time":"2020-07-21T08:17:56Z","timestamp":1595319476000},"page":"602-612","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":77,"title":["Editor's Choice \u2013 Trends in Lower Extremity Amputation Incidence in European Union 15+ Countries 1990\u20132017"],"prefix":"10.1016","volume":"60","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0849-671X","authenticated-orcid":false,"given":"Will","family":"Hughes","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard","family":"Goodall","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8092-0883","authenticated-orcid":false,"given":"Justin D.","family":"Salciccioli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3498-2511","authenticated-orcid":false,"given":"Dominic C.","family":"Marshall","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alun H.","family":"Davies","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph","family":"Shalhoub","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ejvs.2020.05.037_bib1","doi-asserted-by":"crossref","first-page":"1214","DOI":"10.1177\/000313481007601120","article-title":"Epidemiology of post-traumatic limb amputation: a National Trauma Databank analysis","volume":"76","author":"Barmparas","year":"2010","journal-title":"Am Surg"},{"key":"10.1016\/j.ejvs.2020.05.037_bib2","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1016\/j.avsg.2016.12.015","article-title":"A\u00a0meta-analysis of Long-term mortality and associated risk factors following lower extremity amputation","volume":"42","author":"Stern","year":"2017","journal-title":"Ann Vasc Surg"},{"key":"10.1016\/j.ejvs.2020.05.037_bib3","doi-asserted-by":"crossref","DOI":"10.1136\/bmjopen-2017-016030","article-title":"Progression of disease preceding lower extremity amputation in Denmark: a longitudinal registry study of diagnoses, use of medication and healthcare services 14 years prior to amputation","volume":"7","author":"Jensen","year":"2017","journal-title":"BMJ Open"},{"key":"10.1016\/j.ejvs.2020.05.037_bib4","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1001\/jamasurg.2013.4277","article-title":"Relationship between regional spending on vascular care and amputation rate","volume":"149","author":"Goodney","year":"2014","journal-title":"JAMA Surg"},{"key":"10.1016\/j.ejvs.2020.05.037_bib5","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/j.ejvs.2019.09.006","article-title":"European Society for Vascular Surgery (ESVS) 2020 clinical practice guideline on the management of acute limb ischaemia","volume":"59","author":"Bj\u00f6rck","year":"2020","journal-title":"Eur J Vasc Endovasc Surg"},{"key":"10.1016\/j.ejvs.2020.05.037_bib6","doi-asserted-by":"crossref","first-page":"S1","DOI":"10.1016\/j.ejvs.2019.05.006","article-title":"Global vascular guidelines on the management of chronic limb-threatening ischaemia","volume":"58","author":"Conte","year":"2019","journal-title":"Eur J Vasc Endovasc Surg"},{"key":"10.1016\/j.ejvs.2020.05.037_bib7","doi-asserted-by":"crossref","first-page":"1144","DOI":"10.1111\/j.1464-5491.2011.03279.x","article-title":"Lower extremity amputations \u2013 a review of global variance","volume":"28","author":"Moxey","year":"2011","journal-title":"Diabet Med"},{"key":"10.1016\/j.ejvs.2020.05.037_bib8","article-title":"Trends in peripheral arterial disease incidence and mortality in EU15+ countries 1990- 2017","author":"Goodall","year":"2020","journal-title":"Eur J Prev Cardiol"},{"key":"10.1016\/j.ejvs.2020.05.037_bib9","doi-asserted-by":"crossref","first-page":"880","DOI":"10.1016\/S0140-6736(14)60485-2","article-title":"Deaths in young people aged 0-24 years in the UK compared with the EU15+ countries, 1970-2008: analysis of the WHO Mortality database","volume":"384","author":"Viner","year":"2014","journal-title":"Lancet"},{"key":"10.1016\/j.ejvs.2020.05.037_bib10","article-title":"Respiratory disease mortality in the United Kingdom compared with EU15+ countries in 1985-2015: observational study","volume":"363","author":"Salciccioli","year":"2018","journal-title":"BMJ"},{"key":"10.1016\/j.ejvs.2020.05.037_bib11","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/j.ejvs.2019.08.006","article-title":"Comorbidity patterns among patients with peripheral arterial occlusive disease in Germany: a trend analysis of health insurance claims data","volume":"59","author":"Kreutzburg","year":"2020","journal-title":"Eur J Vasc Endovasc Surg"},{"key":"10.1016\/j.ejvs.2020.05.037_bib12","doi-asserted-by":"crossref","first-page":"1513","DOI":"10.1016\/S0140-6736(16)00618-8","article-title":"Worldwide trends in diabetes since 1980: a pooled analysis of 751 population-based studies with 4.4 million participants","volume":"387","year":"2016","journal-title":"Lancet"},{"key":"10.1016\/j.ejvs.2020.05.037_bib13","doi-asserted-by":"crossref","first-page":"737","DOI":"10.3109\/17453674.2010.519164","article-title":"Lower limb amputations in Trondheim, Norway","volume":"81","author":"Wits\u00f8","year":"2010","journal-title":"Acta Orthop"},{"key":"10.1016\/j.ejvs.2020.05.037_bib14","doi-asserted-by":"crossref","first-page":"2598","DOI":"10.2337\/dc10-0462","article-title":"Fewer major amputations among individuals with diabetes in Finland in 1997-2007: a population-based study","volume":"33","author":"Ikonen","year":"2010","journal-title":"Diabetes Care"},{"key":"10.1016\/j.ejvs.2020.05.037_bib15","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1016\/j.diabres.2009.11.016","article-title":"Trends in lower extremity amputations in people with and without diabetes in England","volume":"87","author":"Vamos","year":"2010","journal-title":"Diabetes Res Clin Pract"},{"key":"10.1016\/j.ejvs.2020.05.037_bib16","doi-asserted-by":"crossref","first-page":"500","DOI":"10.1055\/s-0029-1225333","article-title":"Incidence of lower-limb amputations in the diabetic compared to the non-diabetic population. findings from nationwide insurance data, Germany","volume":"117","author":"Icks","year":"2009","journal-title":"Exp Clin Endocrinol Diabetes"},{"key":"10.1016\/j.ejvs.2020.05.037_bib17","doi-asserted-by":"crossref","first-page":"1686","DOI":"10.2337\/diacare.24.9.1686","article-title":"Epidemiology of nontraumatic lower-extremity amputation in area 7, Madrid, between 1989 and 1999: a population-based study","volume":"24","author":"Calle-Pascual","year":"2001","journal-title":"Diabetes Care"},{"key":"10.1016\/j.ejvs.2020.05.037_bib18","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1016\/j.ejvs.2018.04.017","article-title":"International variations in amputation practice: a VASCUNET report","volume":"56","author":"Behrendt","year":"2018","journal-title":"Eur J Vasc Endovasc Surg"},{"key":"10.1016\/j.ejvs.2020.05.037_bib19","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1111\/j.1464-5491.1995.tb02055.x","article-title":"Comparing the incidence of lower extremity amputations across the world: the global lower extremity amputation study","volume":"12","author":"Unwin","year":"1995","journal-title":"Diabet Med"},{"key":"10.1016\/j.ejvs.2020.05.037_bib20","doi-asserted-by":"crossref","first-page":"1789","DOI":"10.1016\/S0140-6736(18)32279-7","article-title":"Global, regional, and national incidence, prevalence, and years lived with disability for 354 diseases and injuries for 195 countries and territories, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017","volume":"392","year":"2018","journal-title":"Lancet"},{"key":"10.1016\/j.ejvs.2020.05.037_bib21","doi-asserted-by":"crossref","first-page":"1736","DOI":"10.1016\/S0140-6736(18)32203-7","article-title":"Global, regional, and national age-sex specific mortality for 282 causes of death in 195 countries and territories, 1980-2017: a systematic analysis for the Global Burden of Disease Study 2017","volume":"392","year":"2018","journal-title":"Lancet"},{"key":"10.1016\/j.ejvs.2020.05.037_bib23","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1002\/(SICI)1097-0258(20000215)19:3<335::AID-SIM336>3.0.CO;2-Z","article-title":"Permutation tests for joinpoint regression with applications to cancer rates","volume":"19","author":"Kim","year":"2000","journal-title":"Stat Med"},{"key":"10.1016\/j.ejvs.2020.05.037_bib24","doi-asserted-by":"crossref","first-page":"1916","DOI":"10.1161\/CIRCULATIONAHA.115.018931","article-title":"Trends in mortality from ischaemic heart disease and cerebrovascular disease in Europe 1980 to 2009","volume":"133","author":"Hartley","year":"2016","journal-title":"Circulation"},{"key":"10.1016\/j.ejvs.2020.05.037_bib25","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/j.diabres.2017.03.024","article-title":"IDF Diabetes Atlas: global estimates for the prevalence of diabetes for 2015 and 2040","volume":"128","author":"Ogurtsova","year":"2017","journal-title":"Diabetes Res Clin Pract"},{"key":"10.1016\/j.ejvs.2020.05.037_bib26","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1007\/s00125-018-4711-2","article-title":"Global trends in diabetes complications: a review of current evidence","volume":"62","author":"Harding","year":"2019","journal-title":"Diabetologia"},{"key":"10.1016\/j.ejvs.2020.05.037_bib27","doi-asserted-by":"crossref","DOI":"10.1136\/bmjopen-2017-018184","article-title":"Time trends in peripheral artery disease incidence, prevalence and secondary preventive therapy: a cohort study in the Health Improvement Network in the UK","volume":"8","author":"Cea-Soriano","year":"2018","journal-title":"BMJ Open"},{"key":"10.1016\/j.ejvs.2020.05.037_bib28","doi-asserted-by":"crossref","first-page":"1345","DOI":"10.1161\/CIRCULATIONAHA.112.108787","article-title":"Missed opportunities: despite improvement in use of cardioprotective medications among patients with lower-extremity peripheral artery disease, underuse remains","volume":"126","author":"Subherwal","year":"2012","journal-title":"Circulation"},{"key":"10.1016\/j.ejvs.2020.05.037_bib29","doi-asserted-by":"crossref","first-page":"e86","DOI":"10.1016\/j.atherosclerosis.2008.10.023","article-title":"Cardiovascular risk factor control and outcomes in peripheral artery disease patients in the Reduction of Atherothrombosis for Continued Health (REACH) registry","volume":"204","author":"Cacoub","year":"2009","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.ejvs.2020.05.037_bib30","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1001\/jamasurg.2014.1007","article-title":"Fifteen-year trends in lower limb amputation, revascularization, and preventive measures among medicare patients","volume":"150","author":"Goodney","year":"2015","journal-title":"JAMA Surg"},{"key":"10.1016\/j.ejvs.2020.05.037_bib31","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/j.jvs.2006.09.044","article-title":"The adverse effects of race, insurance status, and low income on the rate of amputation in patients presenting with lower extremity ischemia","volume":"45","author":"Eslami","year":"2007","journal-title":"J\u00a0Vasc Surg"},{"key":"10.1016\/j.ejvs.2020.05.037_bib32","doi-asserted-by":"crossref","first-page":"1001","DOI":"10.1016\/j.jvs.2007.11.072","article-title":"A\u00a0census-based analysis of racial disparities in lower extremity amputation rates in Northern Illinois, 1987-2004","volume":"47","author":"Feinglass","year":"2008","journal-title":"J\u00a0Vasc Surg"},{"key":"10.1016\/j.ejvs.2020.05.037_bib33","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1111\/j.1445-2197.2006.03715.x","article-title":"Outcomes of a contemporary amputation series","volume":"76","author":"Lim","year":"2006","journal-title":"ANZ J Surg"},{"key":"10.1016\/j.ejvs.2020.05.037_bib34","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1177\/0309364613490441","article-title":"Incidence of lower limb amputation in Australian hospitals from 2000 to 2010","volume":"38","author":"Dillon","year":"2014","journal-title":"Prosthet Orthot Int"},{"key":"10.1016\/j.ejvs.2020.05.037_bib35","doi-asserted-by":"crossref","first-page":"796","DOI":"10.1111\/ans.15161","article-title":"Regional variations in amputation rates: are regional diabetic foot services the reason?","volume":"89","author":"Lazzarini","year":"2019","journal-title":"ANZ J Surg"},{"key":"10.1016\/j.ejvs.2020.05.037_bib36","doi-asserted-by":"crossref","first-page":"1395","DOI":"10.1016\/S0140-6736(15)60171-4","article-title":"A\u00a0global assessment of civil registration and vital statistics systems: monitoring data quality and progress","volume":"386","author":"Mikklesen","year":"2015","journal-title":"Lancet"}],"container-title":["European Journal of Vascular and Endovascular Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1078588420304639?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1078588420304639?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T11:54:08Z","timestamp":1761047648000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1078588420304639"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,10]]},"references-count":35,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2020,10]]}},"alternative-id":["S1078588420304639"],"URL":"https:\/\/doi.org\/10.1016\/j.ejvs.2020.05.037","relation":{},"ISSN":["1078-5884"],"issn-type":[{"value":"1078-5884","type":"print"}],"subject":[],"published":{"date-parts":[[2020,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Editor's Choice \u2013 Trends in Lower Extremity Amputation Incidence in European Union 15+ Countries 1990\u20132017","name":"articletitle","label":"Article Title"},{"value":"European Journal of Vascular and Endovascular Surgery","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ejvs.2020.05.037","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 European Society for Vascular Surgery. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}]}}