{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,22]],"date-time":"2026-03-22T02:01:17Z","timestamp":1774144877647,"version":"3.50.1"},"reference-count":28,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2020,12,1]],"date-time":"2020-12-01T00:00:00Z","timestamp":1606780800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,12,1]],"date-time":"2020-12-01T00:00:00Z","timestamp":1606780800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T00:00:00Z","timestamp":1638316800000},"content-version":"vor","delay-in-days":365,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/100008376","name":"Helsingin ja Uudenmaan Sairaanhoitopiiri","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100008376","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","ejves.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Vascular and Endovascular Surgery"],"published-print":{"date-parts":[[2020,12]]},"DOI":"10.1016\/j.ejvs.2020.08.044","type":"journal-article","created":{"date-parts":[[2020,10,8]],"date-time":"2020-10-08T09:09:02Z","timestamp":1602148142000},"page":"809-815","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":12,"title":["Predictive Factors for Pre-operative Recurrence of Cerebrovascular Symptoms in Symptomatic Carotid Stenosis"],"prefix":"10.1016","volume":"60","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8450-2125","authenticated-orcid":false,"given":"Henrietta","family":"Eriksson","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0000-8163","authenticated-orcid":false,"given":"Suvi","family":"Koskinen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4588-050X","authenticated-orcid":false,"given":"Krista","family":"Nuotio","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hanna M.","family":"Heikkil\u00e4","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pirkka","family":"Vikatmaa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Heli","family":"Silvennoinen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leena","family":"Valanne","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mikko I.","family":"M\u00e4yr\u00e4np\u00e4\u00e4","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Petri T.","family":"Kovanen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6831-5688","authenticated-orcid":false,"given":"Lauri","family":"Soinne","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Perttu J.","family":"Lindsberg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Petra","family":"Ij\u00e4s","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ejvs.2020.08.044_bib1","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1212\/01.WNL.0000110311.09970.83","article-title":"Early risk of recurrence by subtype of ischemic stroke in population-based incidence studies","volume":"62","author":"Lovett","year":"2004","journal-title":"Neurology"},{"key":"10.1016\/j.ejvs.2020.08.044_bib2","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/j.ejvs.2017.06.021","article-title":"Editor's choice \u2013 management of atherosclerotic carotid and vertebral artery disease: 2017 clinical practice guidelines of the European Society for Vascular Surgery (ESVS)","volume":"55","author":"Naylor","year":"2018","journal-title":"Eur J Vasc Endovasc Surg"},{"key":"10.1016\/j.ejvs.2020.08.044_bib3","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1159\/000131083","article-title":"Guidelines for management of ischaemic stroke and transient ischaemic attack 2008","volume":"25","year":"2008","journal-title":"Cerebrovasc Dis"},{"key":"10.1016\/j.ejvs.2020.08.044_bib4","doi-asserted-by":"crossref","first-page":"3423","DOI":"10.1161\/STROKEAHA.115.010764","article-title":"Summary of evidence on early carotid intervention for recently symptomatic stenosis based on meta-analysis of current risks","volume":"46","author":"De Rango","year":"2015","journal-title":"Stroke"},{"key":"10.1016\/j.ejvs.2020.08.044_bib5","doi-asserted-by":"crossref","first-page":"e46","DOI":"10.1161\/STR.0000000000000158","article-title":"2018 guidelines for the early management of patients with acute ischemic stroke: a guideline for healthcare professionals from the American Heart Association\/American Stroke Association","volume":"49","author":"Powers","year":"2018","journal-title":"Stroke"},{"key":"10.1016\/j.ejvs.2020.08.044_bib6","doi-asserted-by":"crossref","first-page":"2105","DOI":"10.1016\/S0140-6736(98)11415-0","article-title":"Prediction of benefit from carotid endarterectomy in individual patients: a risk-modelling study. European Carotid Surgery Trialists' Collaborative Group","volume":"353","author":"Rothwell","year":"1999","journal-title":"Lancet"},{"key":"10.1016\/j.ejvs.2020.08.044_bib7","article-title":"Risk factors associated with cerebrovascular recurrence in symptomatic carotid disease: a comparative study of carotid plaque morphology, microemboli assessment and the European Carotid Surgery Trial risk model","volume":"3","author":"Altaf","year":"2014","journal-title":"J\u00a0Am Heart Assoc"},{"key":"10.1016\/j.ejvs.2020.08.044_bib8","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1080\/07853890.2018.1494851","article-title":"Morphology and histology of silent and symptom-causing atherosclerotic carotid plaques\u2013Rationale and design of the Helsinki Carotid Endarterectomy Study 2 (the HeCES2)","volume":"50","author":"Nuotio","year":"2018","journal-title":"Ann Med"},{"key":"10.1016\/j.ejvs.2020.08.044_bib9","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1016\/j.ejvs.2012.04.015","article-title":"The European society for vascular surgery guidelines for carotid intervention: an updated independent assessment and literature review","volume":"44","author":"Kakisis","year":"2012","journal-title":"Eur J Vasc Endovasc Surg"},{"key":"10.1016\/j.ejvs.2020.08.044_bib10","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1161\/STR.0b013e3181f7d043","article-title":"Guidelines for the prevention of stroke in patients with stroke or transient ischemic attack","volume":"42","author":"Furie","year":"2011","journal-title":"Stroke"},{"key":"10.1016\/j.ejvs.2020.08.044_bib11","doi-asserted-by":"crossref","first-page":"498","DOI":"10.1212\/WNL.0000000000002354","article-title":"Recurrent stroke in symptomatic carotid stenosis awaiting revascularization: a pooled analysis","volume":"86","author":"Johansson","year":"2016","journal-title":"Neurology"},{"key":"10.1016\/j.ejvs.2020.08.044_bib12","doi-asserted-by":"crossref","first-page":"738","DOI":"10.1212\/WNL.0b013e31822b00cf","article-title":"Stroke recurrence within the time window recommended for carotid endarterectomy","volume":"77","author":"Marnane","year":"2011","journal-title":"Neurology"},{"key":"10.1016\/j.ejvs.2020.08.044_bib13","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1111\/j.1747-4949.2012.00790.x","article-title":"Risk of recurrent stroke before carotid endarterectomy: the ANSYSCAP study","volume":"8","author":"Johansson","year":"2013","journal-title":"Int J Stroke"},{"key":"10.1016\/j.ejvs.2020.08.044_bib14","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/j.ejvs.2014.11.004","article-title":"Risk of early recurrent stroke in symptomatic carotid stenosis","volume":"49","author":"Str\u00f6mberg","year":"2015","journal-title":"Eur J Vasc Endovasc Surg"},{"key":"10.1016\/j.ejvs.2020.08.044_bib15","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1177\/1747493015609777","article-title":"Risk of early recurrent stroke in symptomatic carotid stenosis after best medical therapy and before endarterectomy","volume":"11","author":"Shahidi","year":"2016","journal-title":"Int J Stroke"},{"key":"10.1016\/j.ejvs.2020.08.044_bib16","doi-asserted-by":"crossref","first-page":"1415","DOI":"10.1056\/NEJM199811123392002","article-title":"Benefit of carotid endarterectomy in patients with symptomatic moderate or severe stenosis. North American Symptomatic Carotid Endarterectomy Trial Collaborators","volume":"339","author":"Barnett","year":"1998","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.ejvs.2020.08.044_bib17","doi-asserted-by":"crossref","first-page":"1379","DOI":"10.1016\/S0140-6736(97)09292-1","article-title":"Randomised trial of endarterectomy for recently symptomatic carotid stenosis: final results of the MRC European Carotid Surgery Trial (ECST)","volume":"351","year":"1998","journal-title":"Lancet"},{"key":"10.1016\/j.ejvs.2020.08.044_bib18","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1016\/j.oret.2016.08.003","article-title":"Ocular arterial occlusive disorders and carotid artery disease","volume":"1","author":"Hayreh","year":"2017","journal-title":"Ophthalmol Retin"},{"key":"10.1016\/j.ejvs.2020.08.044_bib19","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1016\/j.preteyeres.2011.05.001","article-title":"Acute retinal arterial occlusive disorders","volume":"30","author":"Hayreh","year":"2011","journal-title":"Prog Retin Eye Res"},{"key":"10.1016\/j.ejvs.2020.08.044_bib20","doi-asserted-by":"crossref","first-page":"926","DOI":"10.1161\/01.CIR.103.7.926","article-title":"Pravastatin treatment increases collagen content and decreases lipid content, inflammation, metalloproteinases, and cell death in human carotid plaques: implications for plaque stabilization","volume":"103","author":"Crisby","year":"2001","journal-title":"Circulation"},{"key":"10.1016\/j.ejvs.2020.08.044_bib21","doi-asserted-by":"crossref","first-page":"2723","DOI":"10.1161\/STROKEAHA.117.018140","article-title":"Effects of statin intensity and adherence on the long-term prognosis after acute ischemic stroke","volume":"48","author":"Kim","year":"2017","journal-title":"Stroke"},{"key":"10.1016\/j.ejvs.2020.08.044_bib22","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1056\/NEJMoa061894","article-title":"High-dose atorvastatin after stroke or transient ischemic attack","volume":"355","author":"Amarenco","year":"2006","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.ejvs.2020.08.044_bib23","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1161\/01.STR.0000198813.56398.14","article-title":"Markers of inflammation and infection influence the outcome of patients with baseline asymptomatic carotid lesions: a 5-year follow-up study","volume":"37","author":"Corrado","year":"2006","journal-title":"Stroke"},{"key":"10.1016\/j.ejvs.2020.08.044_bib24","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1097\/MOH.0b013e32835673c2","article-title":"Determinants of fibrin formation, structure, and function","volume":"19","author":"Wolberg","year":"2012","journal-title":"Curr Opin Hematol"},{"key":"10.1016\/j.ejvs.2020.08.044_bib25","doi-asserted-by":"crossref","first-page":"2070","DOI":"10.1182\/blood-2008-07-167411","article-title":"Systemic blood coagulation activation in acute coronary syndromes","volume":"113","author":"Undas","year":"2009","journal-title":"Blood"},{"key":"10.1016\/j.ejvs.2020.08.044_bib26","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1089\/met.2018.0058","article-title":"Can the plasma concentration ratio of triglyceride\/high-density lipoprotein cholesterol identify individuals at high risk of cardiovascular disease during 40-year follow-up?","volume":"16","author":"Lind","year":"2018","journal-title":"Metab Syndr Relat Disord"},{"key":"10.1016\/j.ejvs.2020.08.044_bib27","doi-asserted-by":"crossref","first-page":"48S","DOI":"10.1016\/S0002-9343(98)00212-5","article-title":"Epidemiologic aspects of lipid abnormalities","volume":"105","author":"Criqui","year":"1998","journal-title":"Am J Med"},{"key":"10.1016\/j.ejvs.2020.08.044_bib28","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1016\/j.cca.2017.10.028","article-title":"Biomarkers of cerebral microembolic signals","volume":"475","author":"Yin","year":"2017","journal-title":"Clin Chim Acta"}],"container-title":["European Journal of Vascular and Endovascular Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1078588420307851?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1078588420307851?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T11:54:16Z","timestamp":1761047656000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1078588420307851"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,12]]},"references-count":28,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2020,12]]}},"alternative-id":["S1078588420307851"],"URL":"https:\/\/doi.org\/10.1016\/j.ejvs.2020.08.044","relation":{},"ISSN":["1078-5884"],"issn-type":[{"value":"1078-5884","type":"print"}],"subject":[],"published":{"date-parts":[[2020,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Predictive Factors for Pre-operative Recurrence of Cerebrovascular Symptoms in Symptomatic Carotid Stenosis","name":"articletitle","label":"Article Title"},{"value":"European Journal of Vascular and Endovascular Surgery","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ejvs.2020.08.044","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 European Society for Vascular Surgery. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}]}}