{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T03:34:29Z","timestamp":1790048069075,"version":"4.0.1"},"reference-count":25,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2023,2,1]],"date-time":"2023-02-01T00:00:00Z","timestamp":1675209600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,2,1]],"date-time":"2023-02-01T00:00:00Z","timestamp":1675209600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,12,7]],"date-time":"2022-12-07T00:00:00Z","timestamp":1670371200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000272","name":"National Institute for Health and Care Research","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000272","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100013342","name":"NIHR Imperial Biomedical Research Centre","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100013342","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","ejves.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Vascular and Endovascular Surgery"],"published-print":{"date-parts":[[2023,2]]},"DOI":"10.1016\/j.ejvs.2022.10.018","type":"journal-article","created":{"date-parts":[[2022,10,17]],"date-time":"2022-10-17T00:20:38Z","timestamp":1665966038000},"page":"291-297","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":24,"title":["Systematic Review and Meta-Analysis of the Pooled Rate of Post-Thrombotic Syndrome After Isolated Distal Deep Venous Thrombosis"],"prefix":"10.1016","volume":"65","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4804-9343","authenticated-orcid":false,"given":"Benedict R.H.","family":"Turner","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4542-1100","authenticated-orcid":false,"given":"Ankur","family":"Thapar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sara","family":"Jasionowska","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Azfar","family":"Javed","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew","family":"Machin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rebecca","family":"Lawton","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5913-2273","authenticated-orcid":false,"given":"Adam M.","family":"Gwozdz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5261-6913","authenticated-orcid":false,"given":"Alun H.","family":"Davies","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ejvs.2022.10.018_bib1","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1182\/asheducation-2016.1.413","article-title":"The post-thrombotic syndrome","volume":"2016","author":"Kahn","year":"2016","journal-title":"Hematology Am Soc Hematol Educ Program"},{"key":"10.1016\/j.ejvs.2022.10.018_bib2","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1016\/j.thromres.2017.07.026","article-title":"Epidemiology of the post-thrombotic syndrome","volume":"164","author":"Galanaud","year":"2018","journal-title":"Thromb Res"},{"key":"10.1016\/j.ejvs.2022.10.018_bib3","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1001\/archinte.158.6.585","article-title":"Trends in the incidence of deep vein thrombosis and pulmonary embolism: a 25-year population-based study","volume":"158","author":"Silverstein","year":"1998","journal-title":"Arch Intern Med"},{"key":"10.1016\/j.ejvs.2022.10.018_bib4","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1016\/j.jvsv.2015.08.005","article-title":"Predictors of the post-thrombotic syndrome and their effect on the therapeutic management of deep vein thrombosis","volume":"4","author":"Galanaud","year":"2016","journal-title":"J\u00a0Vasc Surg Venous Lymphat Disord"},{"key":"10.1016\/j.ejvs.2022.10.018_bib5","article-title":"Treatment of distal deep vein thrombosis","volume":"4","author":"Kirkilesis","year":"2020","journal-title":"Cochrane Database Syst Rev"},{"key":"10.1016\/j.ejvs.2022.10.018_bib6","doi-asserted-by":"crossref","first-page":"857","DOI":"10.1111\/jth.14728","article-title":"Long-term risk of postthrombotic syndrome after symptomatic distal deep vein thrombosis: The CACTUS-PTS study","volume":"18","author":"Galanaud","year":"2020","journal-title":"J\u00a0Thromb Haemost"},{"key":"10.1016\/j.ejvs.2022.10.018_bib7","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/j.thromres.2021.09.004","article-title":"Two weeks of low molecular weight heparin for isolated symptomatic distal vein thrombosis (TWISTER study)","volume":"207","author":"Merriman","year":"2021","journal-title":"Thromb Res"},{"key":"10.1016\/j.ejvs.2022.10.018_bib8","doi-asserted-by":"crossref","first-page":"939","DOI":"10.1111\/j.1538-7836.2005.01333.x","article-title":"Relation between quality of anticoagulant treatment and the development of the postthrombotic syndrome","volume":"3","author":"van Dongen","year":"2005","journal-title":"J\u00a0Thromb Haemost"},{"key":"10.1016\/j.ejvs.2022.10.018_bib9","doi-asserted-by":"crossref","first-page":"967","DOI":"10.1160\/TH16-03-0205","article-title":"Current incidence of venous thromboembolism and comparison with 1998: a community-based study in Western France","volume":"116","author":"Delluc","year":"2016","journal-title":"Thromb Haemost"},{"key":"10.1016\/j.ejvs.2022.10.018_bib10","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1016\/j.ejvs.2015.11.001","article-title":"Analysis of 1,338 patients with acute lower limb deep venous thrombosis (DVT) supports the inadequacy of the term \u201cproximal DVT\u201d","volume":"51","author":"De Maeseneer","year":"2016","journal-title":"Eur J Vasc Endovasc Surg"},{"key":"10.1016\/j.ejvs.2022.10.018_bib11","doi-asserted-by":"crossref","first-page":"n71","DOI":"10.1136\/bmj.n71","article-title":"The PRISMA 2020 statement: an updated guideline for reporting systematic reviews","volume":"372","author":"Page","year":"2021","journal-title":"BMJ"},{"key":"10.1016\/j.ejvs.2022.10.018_bib12","unstructured":"Bonfield M. The response of lower limb deep vein thrombosis to anticoagulation therapy: resolution, recurrence and post thrombotic syndrome. https:\/\/uwe-repository.worktribe.com\/output\/14910012016 [Accessed 6 June 2022]."},{"key":"10.1016\/j.ejvs.2022.10.018_bib13","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1016\/j.jvsv.2012.07.003","article-title":"Post-thrombotic syndrome 3 years after deep venous thrombosis in the thrombosis and pulmonary embolism in out-patients (TULIPA) PLUS registry","volume":"1","author":"Hach-Wunderle","year":"2013","journal-title":"J\u00a0Vasc Surg Venous Lymphat Disord"},{"key":"10.1016\/j.ejvs.2022.10.018_bib14","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1177\/0268355517698620","article-title":"Long-term quality of life and postthrombotic syndrome in women after an episode of venous thromboembolism","volume":"33","author":"Ljungqvist","year":"2018","journal-title":"Phlebology"},{"key":"10.1016\/j.ejvs.2022.10.018_bib15","doi-asserted-by":"crossref","first-page":"2671","DOI":"10.1111\/j.1538-7836.2005.01648.x","article-title":"The post-thrombotic syndrome: risk factors and impact on the course of thrombotic disease","volume":"3","author":"Stain","year":"2005","journal-title":"J\u00a0Thromb Haemost"},{"key":"10.1016\/j.ejvs.2022.10.018_bib16","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1016\/j.jvsv.2016.05.008","article-title":"Time taken to the maximum increase in the oxygenated hemoglobin level in calf muscle as a predictor of mild and moderate post-thrombotic syndrome","volume":"4","author":"Yamaki","year":"2016","journal-title":"J\u00a0Vasc Surg Venous Lymphat Disord"},{"key":"10.1016\/j.ejvs.2022.10.018_bib17","doi-asserted-by":"crossref","first-page":"880","DOI":"10.1016\/S0140-6736(13)61902-9","article-title":"Compression stockings to prevent post-thrombotic syndrome: a randomised placebo-controlled trial","volume":"383","author":"Kahn","year":"2014","journal-title":"Lancet"},{"key":"10.1016\/j.ejvs.2022.10.018_bib18","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1016\/j.chest.2015.11.026","article-title":"Antithrombotic therapy for VTE disease: CHEST guideline and expert panel report","volume":"149","author":"Kearon","year":"2016","journal-title":"Chest"},{"key":"10.1016\/j.ejvs.2022.10.018_bib19","unstructured":"NICE. Venous thromboembolic diseases : NG158. https:\/\/www.nice.org.uk\/guidance\/ng158 [Accessed 6 June 2022]."},{"key":"10.1016\/j.ejvs.2022.10.018_bib20","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.ejvs.2020.09.023","article-title":"Editor's choice - European society for vascular surgery (ESVS) 2021 clinical practice guidelines on the management of venous thrombosis","volume":"61","author":"Kakkos","year":"2021","journal-title":"Eur J Vasc Endovasc Surg"},{"key":"10.1016\/j.ejvs.2022.10.018_bib21","first-page":"11","article-title":"Compression hosiery to avoid post-thrombotic syndrome (CHAPS) protocol for a randomised controlled trial (ISRCTN73041168)","author":"Thapar","year":"2021","journal-title":"BMJ Open"},{"key":"10.1016\/j.ejvs.2022.10.018_bib22","doi-asserted-by":"crossref","first-page":"556","DOI":"10.1016\/S2352-3026(16)30131-4","article-title":"Anticoagulant therapy for symptomatic calf deep vein thrombosis (CACTUS): a randomised, double-blind, placebo-controlled trial","volume":"3","author":"Righini","year":"2016","journal-title":"Lancet Haematol"},{"key":"10.1016\/j.ejvs.2022.10.018_bib23","doi-asserted-by":"crossref","first-page":"2309","DOI":"10.1182\/blood.V126.23.2309.2309","article-title":"Post-thrombotic syndrome and quality-of-life after venous thromboembolism in young and middle-aged women. Conference Abstract","volume":"126","author":"Ljungqvist","year":"2015","journal-title":"Blood"},{"key":"10.1016\/j.ejvs.2022.10.018_bib24","first-page":"7","article-title":"Management and outcomes of isolated distal deep vein thrombosis in hospitalized patients: A single centre retrospective cohort study","volume":"12","author":"Elmi","year":"2018","journal-title":"Italian J Med"},{"key":"10.1016\/j.ejvs.2022.10.018_bib25","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1186\/s12959-020-00253-8","article-title":"Predictors of long-term post-thrombotic syndrome following high proximal deep vein thrombosis: a cross-sectional study","volume":"19","author":"Engeseth","year":"2021","journal-title":"Thromb J"}],"container-title":["European Journal of Vascular and Endovascular Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1078588422006219?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1078588422006219?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T12:00:09Z","timestamp":1761048009000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1078588422006219"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,2]]},"references-count":25,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2023,2]]}},"alternative-id":["S1078588422006219"],"URL":"https:\/\/doi.org\/10.1016\/j.ejvs.2022.10.018","relation":{},"ISSN":["1078-5884"],"issn-type":[{"value":"1078-5884","type":"print"}],"subject":[],"published":{"date-parts":[[2023,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Systematic Review and Meta-Analysis of the Pooled Rate of Post-Thrombotic Syndrome After Isolated Distal Deep Venous Thrombosis","name":"articletitle","label":"Article Title"},{"value":"European Journal of Vascular and Endovascular Surgery","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ejvs.2022.10.018","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 The Authors. Published by Elsevier B.V. on behalf of European Society for Vascular Surgery.","name":"copyright","label":"Copyright"}]}}