{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,20]],"date-time":"2026-07-20T16:04:11Z","timestamp":1784563451425,"version":"3.55.0"},"reference-count":36,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,6,18]],"date-time":"2026-06-18T00:00:00Z","timestamp":1781740800000},"content-version":"vor","delay-in-days":168,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.jp","ejvesreports.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["EJVES Vascular Forum"],"published-print":{"date-parts":[[2026]]},"DOI":"10.1016\/j.ejvsvf.2026.06.004","type":"journal-article","created":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T23:43:34Z","timestamp":1782258214000},"page":"37-44","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Endo-Bentall Repair for Inoperable Aortic Disease: Balancing Innovation and Ethical Responsibility"],"prefix":"10.1016","volume":"66","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8339-9130","authenticated-orcid":false,"given":"Geoffrey","family":"Ying","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Niklas","family":"Juth","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3273-8726","authenticated-orcid":false,"given":"Anders","family":"Wanhainen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rickard","family":"Lindblom","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4413-9736","authenticated-orcid":false,"given":"Stefan","family":"James","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6445-0575","authenticated-orcid":false,"given":"Carlota","family":"Fernandez Prendes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kevin","family":"Mani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ejvsvf.2026.06.004_bib1","doi-asserted-by":"crossref","DOI":"10.1053\/j.semvascsurg.2026.05.003","article-title":"Endo-Bentall \u2013 current data on safety and efficacy","author":"Shehab","year":"2026","journal-title":"Semin Vasc Surg"},{"key":"10.1016\/j.ejvsvf.2026.06.004_bib2","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1016\/j.ejvs.2023.11.002","article-title":"Editor\u2019s choice -- European Society for Vascular Surgery (ESVS) 2024 clinical practice guidelines on the management of abdominal aorto-iliac artery aneurysms","volume":"67","author":"Wanhainen","year":"2024","journal-title":"Eur J Vasc Endovasc Surg"},{"key":"10.1016\/j.ejvsvf.2026.06.004_bib3","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1016\/j.ejvs.2022.12.031","article-title":"Editor\u2019s choice - Focused update on patients treated with the nellix EndoVascular Aneurysm Sealing (EVAS) system from the European Society for Vascular Surgery (ESVS) abdominal aortic aneurysm clinical practice guidelines","volume":"65","author":"Boyle","year":"2023","journal-title":"Eur J Vasc Endovasc Surg"},{"key":"10.1016\/j.ejvsvf.2026.06.004_bib4","doi-asserted-by":"crossref","first-page":"965","DOI":"10.1001\/jamasurg.2023.2934","article-title":"Management of endoleaks after elective infrarenal aortic endovascular aneurysm repair: a review","volume":"158","author":"Cifuentes","year":"2023","journal-title":"JAMA Surg"},{"key":"10.1016\/j.ejvsvf.2026.06.004_bib5","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/j.ejvs.2020.11.004","article-title":"Progressive device failure at long term follow up of the nellix EndoVascular Aneurysm Sealing (EVAS) system","volume":"61","author":"Singh","year":"2021","journal-title":"Eur J Vasc Endovasc Surg"},{"key":"10.1016\/j.ejvsvf.2026.06.004_bib6","doi-asserted-by":"crossref","first-page":"1375","DOI":"10.1007\/s10237-016-0769-2","article-title":"Cyclic three-dimensional wall motion of the human ascending and abdominal aorta characterised by time-resolved three-dimensional ultrasound speckle tracking","volume":"15","author":"Wittek","year":"2016","journal-title":"Biomech Model Mechanobiol"},{"key":"10.1016\/j.ejvsvf.2026.06.004_bib7","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1093\/ejcts\/ezaa306","article-title":"Important longitudinal and circumferential pulsatile changes in zone 0 of the aorta during the cardiac cycle","volume":"59","author":"Belvroy","year":"2020","journal-title":"Eur J Cardiothorac Surg"},{"key":"10.1016\/j.ejvsvf.2026.06.004_bib8","doi-asserted-by":"crossref","first-page":"1559","DOI":"10.1016\/j.jvs.2023.05.014","article-title":"A meta-analysis on the effect of proximal landing zone location on stroke and mortality in thoracic endovascular aortic repair","volume":"78","author":"Ma","year":"2023","journal-title":"J Vasc Surg"},{"key":"10.1016\/j.ejvsvf.2026.06.004_bib9","doi-asserted-by":"crossref","first-page":"znag008","DOI":"10.1093\/bjs\/znag008","article-title":"Stroke risk and mid-term survival by proximal extent of endovascular aortic repair","volume":"113","author":"Jonsson","year":"2026","journal-title":"Br J Surg"},{"key":"10.1016\/j.ejvsvf.2026.06.004_bib10","doi-asserted-by":"crossref","first-page":"480","DOI":"10.1016\/j.jaccas.2019.11.071","article-title":"First-in-human Endo-Bentall procedure for simultaneous treatment of the ascending aorta and aortic valve","volume":"2","author":"Felipe Gaia","year":"2020","journal-title":"JACC Case Rep"},{"key":"10.1016\/j.ejvsvf.2026.06.004_bib11","doi-asserted-by":"crossref","first-page":"46","DOI":"10.21037\/acs-2021-taes-15","article-title":"Endo-Bentall: is this feasible?","volume":"11","author":"Grimm","year":"2022","journal-title":"Ann Cardiothorac Surg"},{"key":"10.1016\/j.ejvsvf.2026.06.004_bib12","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1136\/jme.2010.035535","article-title":"End-of-life decisions as bedside rationing. An ethical analysis of life support restrictions in an Indian neonatal unit","volume":"36","author":"Miljeteig","year":"2010","journal-title":"J Med Ethics"},{"key":"10.1016\/j.ejvsvf.2026.06.004_bib13","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1467-8519.1993.tb00268.x","article-title":"Moral philosophy and public policy: the case of NRTs","volume":"7","author":"Kymlicka","year":"1993","journal-title":"Bioethics"},{"key":"10.1016\/j.ejvsvf.2026.06.004_bib14","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1080\/15265161.2019.1665402","article-title":"Principles of Biomedical Ethics","volume":"19","author":"Beauchamp","year":"2019","journal-title":"Am J Bioeth"},{"key":"10.1016\/j.ejvsvf.2026.06.004_bib15","doi-asserted-by":"crossref","first-page":"e334","DOI":"10.1161\/CIR.0000000000001106","article-title":"2022 ACC\/AHA guideline for the diagnosis and management of aortic disease: a report of the American Heart Association\/American College of Cardiology Joint Committee on Clinical Practice Guidelines","volume":"146","author":"Isselbacher","year":"2022","journal-title":"Circulation"},{"key":"10.1016\/j.ejvsvf.2026.06.004_bib16","doi-asserted-by":"crossref","first-page":"615","DOI":"10.3390\/jcm9030615","article-title":"Life expectancy after surgery for ascending aortic aneurysm","volume":"9","author":"Hernandez-Vaquero","year":"2020","journal-title":"J Clin Med"},{"key":"10.1016\/j.ejvsvf.2026.06.004_bib17","doi-asserted-by":"crossref","first-page":"1846","DOI":"10.1161\/CIRCULATIONAHA.117.031264","article-title":"Insights from the International Registry of Acute Aortic Dissection: a 20-year experience of collaborative clinical research","volume":"137","author":"Evangelista","year":"2018","journal-title":"Circulation"},{"key":"10.1016\/j.ejvsvf.2026.06.004_bib18","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1016\/j.athoracsur.2018.09.052","article-title":"Risk prediction model for major adverse outcome in proximal thoracic aortic surgery","volume":"107","author":"Wagner","year":"2019","journal-title":"Ann Thorac Surg"},{"key":"10.1016\/j.ejvsvf.2026.06.004_bib19","doi-asserted-by":"crossref","DOI":"10.1161\/CIRCINTERVENTIONS.123.013348","article-title":"First-in-human endovascular aortic root repair (Endo-Bentall) for acute type A dissection","volume":"16","author":"Ghoreishi","year":"2023","journal-title":"Circ Cardiovasc Interv"},{"key":"10.1016\/j.ejvsvf.2026.06.004_bib20","doi-asserted-by":"crossref","DOI":"10.1161\/CIRCINTERVENTIONS.122.012848","article-title":"Endo-Bentall procedure using off-the-shelf catheter devices to repair an aorto-atrial fistula","volume":"16","author":"Leshnower","year":"2023","journal-title":"Circ Cardiovasc Interv"},{"key":"10.1016\/j.ejvsvf.2026.06.004_bib21","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1177\/15266028211065959","article-title":"Modular Endo-Bentall procedure using a \u201cRendez-Vous Access.\u201d","volume":"29","author":"Gandet","year":"2022","journal-title":"J Endovasc Ther"},{"key":"10.1016\/j.ejvsvf.2026.06.004_bib22","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1016\/j.ejvs.2025.07.026","article-title":"The Endo-Bentall procedure in the treatment of ascending aorta pathologies: a scoping review","volume":"71","author":"Shehab","year":"2026","journal-title":"Eur J Vasc Endovasc Surg"},{"key":"10.1016\/j.ejvsvf.2026.06.004_bib27","author":"Gustavsson"},{"key":"10.1016\/j.ejvsvf.2026.06.004_bib28","first-page":"3137","article-title":"Phase 1 clinical trials in end-stage cancer: patient understanding of trial premises and motives for participation","volume":"21","author":"Godskesen","year":"2013","journal-title":"Support Care Cancer"},{"issue":"Suppl. 1","key":"10.1016\/j.ejvsvf.2026.06.004_bib29","doi-asserted-by":"crossref","first-page":"S2","DOI":"10.1016\/S1743-9191(13)60003-5","article-title":"Ethics and surgical innovation: challenges to the professionalism of surgeons","volume":"11","author":"Angelos","year":"2013","journal-title":"Int J Surg"},{"key":"10.1016\/j.ejvsvf.2026.06.004_bib30","doi-asserted-by":"crossref","first-page":"1113","DOI":"10.1016\/S0140-6736(10)61116-6","article-title":"Ethical challenges of innovative surgery: a response to the IDEAL recommendations","volume":"376","author":"Johnson","year":"2010","journal-title":"Lancet"},{"key":"10.1016\/j.ejvsvf.2026.06.004_bib31","doi-asserted-by":"crossref","DOI":"10.1097\/MD.0000000000003790","article-title":"Surgical innovation: the ethical agenda: a systematic review","volume":"95","author":"Broekman","year":"2016","journal-title":"Medicine (Baltimore)"},{"key":"10.1016\/j.ejvsvf.2026.06.004_bib32","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1016\/j.ejvs.2008.05.006","article-title":"When does the \u2018learning curve\u2019 of innovative interventions become questionable practice?","volume":"36","author":"Healey","year":"2008","journal-title":"Eur J Vasc Endovasc Surg"},{"key":"10.1016\/j.ejvsvf.2026.06.004_bib33","series-title":"StatPearls [Internet]. Treasure Island","article-title":"Informed consent","author":"Shah","year":"2025"},{"key":"10.1016\/j.ejvsvf.2026.06.004_bib34","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1111\/j.1748-720X.2009.00352.x","article-title":"Vulnerable brains: research ethics and neurosurgical patients","volume":"37","author":"Ford","year":"2009","journal-title":"J Law Med Ethics"},{"key":"10.1016\/j.ejvsvf.2026.06.004_bib35","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1080\/15265161.2014.957416","article-title":"Ethical justifications for access to unapproved medical interventions: an argument for (limited) patient obligations","volume":"14","author":"Walker","year":"2014","journal-title":"Am J Bioeth"},{"key":"10.1016\/j.ejvsvf.2026.06.004_bib36","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1177\/15266028221105186","article-title":"The impact of the proctor assistance for a safe learning curve in the development of a complex aortic endovascular program","volume":"31","author":"Gouveia","year":"2024","journal-title":"J Endovasc Ther"},{"key":"10.1016\/j.ejvsvf.2026.06.004_bib37","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1186\/s12916-017-0910-9","article-title":"Ethics review in compassionate use","volume":"15","author":"Borysowski","year":"2017","journal-title":"BMC Med"},{"key":"10.1016\/j.ejvsvf.2026.06.004_bib38","doi-asserted-by":"crossref","first-page":"841","DOI":"10.1111\/imj.12530","article-title":"Dilemmas in the compassionate supply of investigational cancer drugs","volume":"44","author":"Lewis","year":"2014","journal-title":"Intern Med J"},{"key":"10.1016\/j.ejvsvf.2026.06.004_bib39","doi-asserted-by":"crossref","unstructured":"Bristol scandal | Circulation [Internet]. doi:10.1161\/hc3201.097067.","DOI":"10.1161\/hc3201.097067"},{"key":"10.1016\/j.ejvsvf.2026.06.004_bib40","doi-asserted-by":"crossref","DOI":"10.1136\/bmj.f3012","article-title":"IDEAL framework for surgical innovation 1: the idea and development stages","volume":"346","author":"McCulloch","year":"2013","journal-title":"BMJ"}],"container-title":["EJVES Vascular Forum"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2666688X26000444?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2666688X26000444?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,7,20]],"date-time":"2026-07-20T15:15:18Z","timestamp":1784560518000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2666688X26000444"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026]]},"references-count":36,"alternative-id":["S2666688X26000444"],"URL":"https:\/\/doi.org\/10.1016\/j.ejvsvf.2026.06.004","relation":{},"ISSN":["2666-688X"],"issn-type":[{"value":"2666-688X","type":"print"}],"subject":[],"published":{"date-parts":[[2026]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Endo-Bentall Repair for Inoperable Aortic Disease: Balancing Innovation and Ethical Responsibility","name":"articletitle","label":"Article Title"},{"value":"EJVES Vascular Forum","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ejvsvf.2026.06.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Author(s). Published by Elsevier Ltd on behalf of European Society for Vascular Surgery.","name":"copyright","label":"Copyright"}]}}