{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T02:14:32Z","timestamp":1777601672747,"version":"3.51.4"},"reference-count":9,"publisher":"Elsevier BV","issue":"10","license":[{"start":{"date-parts":[[2022,10,1]],"date-time":"2022-10-01T00:00:00Z","timestamp":1664582400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,10,1]],"date-time":"2022-10-01T00:00:00Z","timestamp":1664582400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,7,6]],"date-time":"2022-07-06T00:00:00Z","timestamp":1657065600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["kireports.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Kidney International Reports"],"published-print":{"date-parts":[[2022,10]]},"DOI":"10.1016\/j.ekir.2022.07.001","type":"journal-article","created":{"date-parts":[[2022,7,11]],"date-time":"2022-07-11T22:17:55Z","timestamp":1657577875000},"page":"2289-2294","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"title":["A Novel AQP2 Sequence Variant Causing Aquaporin-2 Retention in the Cytoplasm and Autosomal Dominant Nephrogenic Diabetes Insipidus"],"prefix":"10.1016","volume":"7","author":[{"given":"Gitte R.","family":"Hinrichs","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sandrine","family":"Baltzer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tamara","family":"Pallien","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Per","family":"Svenningsen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emil B.","family":"Dalgaard","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jens Michael","family":"Hertz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claus","family":"Bistrup","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Boye L.","family":"Jensen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Enno","family":"Klussmann","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ekir.2022.07.001_bib1","doi-asserted-by":"crossref","first-page":"23","DOI":"10.3389\/fphar.2016.00023","article-title":"The trafficking of the water channel Aquaporin-2 in renal principal cells-a potential target for pharmacological intervention in cardiovascular diseases","volume":"7","author":"Vuki\u0107evi\u0107","year":"2016","journal-title":"Front Pharmacol"},{"key":"10.1016\/j.ekir.2022.07.001_bib2","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1038\/357336a0","article-title":"Cloning and characterization of a vasopressin V2 receptor and possible link to nephrogenic diabetes insipidus","volume":"357","author":"Lolait","year":"1992","journal-title":"Nature"},{"key":"10.1016\/j.ekir.2022.07.001_bib3","doi-asserted-by":"crossref","first-page":"1250","DOI":"10.1172\/JCI117079","article-title":"Cloning, characterization, and chromosomal mapping of human aquaporin of collecting duct","volume":"93","author":"Sasaki","year":"1994","journal-title":"J\u00a0Clin Invest"},{"key":"10.1016\/j.ekir.2022.07.001_bib4","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1126\/science.8140421","article-title":"Requirement of human renal water channel aquaporin-2 for vasopressin-dependent concentration of urine","volume":"264","author":"Deen","year":"1994","journal-title":"Science"},{"key":"10.1016\/j.ekir.2022.07.001_bib5","doi-asserted-by":"crossref","first-page":"765","DOI":"10.1038\/s41581-021-00447-x","article-title":"Aquaporin 2 regulation: implications for water balance and polycystic kidney diseases","volume":"17","author":"Olesen","year":"2021","journal-title":"Nat Rev Nephrol"},{"key":"10.1016\/j.ekir.2022.07.001_bib6","doi-asserted-by":"crossref","DOI":"10.3390\/cells9102172","article-title":"AQP2: mutations associated with congenital nephrogenic diabetes insipidus and regulation by post-translational modifications and protein-protein interactions","volume":"9","author":"Gao","year":"2020","journal-title":"Cells"},{"key":"10.1016\/j.ekir.2022.07.001_bib7","doi-asserted-by":"crossref","first-page":"1493","DOI":"10.1681\/ASN.V8101493","article-title":"Aquaporin-2 transfection of Madin-Darby canine kidney cells reconstitutes vasopressin-regulated transcellular osmotic water transport","volume":"8","author":"Deen","year":"1997","journal-title":"J\u00a0Am Soc Nephrol"},{"key":"10.1016\/j.ekir.2022.07.001_bib8","doi-asserted-by":"crossref","DOI":"10.3390\/ijms23020763","article-title":"Aurora kinase A Is involved in controlling the localization of Aquaporin-2 in renal principal cells","volume":"23","author":"Baltzer","year":"2022","journal-title":"Int J Mol Sci"},{"key":"10.1016\/j.ekir.2022.07.001_bib9","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1681\/ASN.2018060668","article-title":"Fluconazole increases osmotic water transport in renal collecting duct through effects on Aquaporin-2 trafficking","volume":"30","author":"Vuki\u0107evi\u0107","year":"2019","journal-title":"J\u00a0Am Soc Nephrol"}],"container-title":["Kidney International Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2468024922014991?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2468024922014991?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,11]],"date-time":"2025-11-11T03:40:57Z","timestamp":1762832457000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2468024922014991"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,10]]},"references-count":9,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2022,10]]}},"alternative-id":["S2468024922014991"],"URL":"https:\/\/doi.org\/10.1016\/j.ekir.2022.07.001","relation":{},"ISSN":["2468-0249"],"issn-type":[{"value":"2468-0249","type":"print"}],"subject":[],"published":{"date-parts":[[2022,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A Novel AQP2 Sequence Variant Causing Aquaporin-2 Retention in the Cytoplasm and Autosomal Dominant Nephrogenic Diabetes Insipidus","name":"articletitle","label":"Article Title"},{"value":"Kidney International Reports","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ekir.2022.07.001","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 International Society of Nephrology. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}