{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,4]],"date-time":"2026-11-04T18:59:47Z","timestamp":1793818787938,"version":"4.6.1"},"reference-count":58,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T00:00:00Z","timestamp":1706745600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T00:00:00Z","timestamp":1706745600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,11,7]],"date-time":"2023-11-07T00:00:00Z","timestamp":1699315200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["kireports.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Kidney International Reports"],"published-print":{"date-parts":[[2024,2]]},"DOI":"10.1016\/j.ekir.2023.11.003","type":"journal-article","created":{"date-parts":[[2023,11,11]],"date-time":"2023-11-11T12:03:57Z","timestamp":1699704237000},"page":"423-435","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":20,"title":["LIF\/JAK2\/STAT1 Signaling Enhances Production of Galactose-Deficient IgA1 by IgA1-Producing Cell Lines Derived From Tonsils of Patients With IgA Nephropathy"],"prefix":"10.1016","volume":"9","author":[{"given":"Koshi","family":"Yamada","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhi-Qiang","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Colin","family":"Reily","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Todd J.","family":"Green","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hitoshi","family":"Suzuki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jan","family":"Novak","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yusuke","family":"Suzuki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ekir.2023.11.003_bib1","doi-asserted-by":"crossref","first-page":"2402","DOI":"10.1056\/NEJMra1206793","article-title":"IgA nephropathy","volume":"368","author":"Wyatt","year":"2013","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.ekir.2023.11.003_bib2","doi-asserted-by":"crossref","first-page":"2325","DOI":"10.1172\/JCI74475","article-title":"The genetics and immunobiology of IgA nephropathy","volume":"124","author":"Kiryluk","year":"2014","journal-title":"J\u00a0Clin Invest"},{"key":"10.1016\/j.ekir.2023.11.003_bib3","doi-asserted-by":"crossref","first-page":"1135","DOI":"10.1111\/j.1523-1755.2004.00486.x","article-title":"Relationship between tonsils and IgA nephropathy as well as indications of tonsillectomy","volume":"65","author":"Xie","year":"2004","journal-title":"Kidney Int"},{"key":"10.1016\/j.ekir.2023.11.003_bib4","doi-asserted-by":"crossref","first-page":"1795","DOI":"10.1681\/ASN.2011050464","article-title":"The pathophysiology of IgA nephropathy","volume":"22","author":"Suzuki","year":"2011","journal-title":"J\u00a0Am Soc Nephrol"},{"key":"10.1016\/j.ekir.2023.11.003_bib5","first-page":"1668","article-title":"Aberrantly glycosylated IgA1 in IgA nephropathy patients is recognized by IgG antibodies with restricted heterogeneity","volume":"119","author":"Suzuki","year":"2009","journal-title":"J\u00a0Clin Invest"},{"key":"10.1016\/j.ekir.2023.11.003_bib6","doi-asserted-by":"crossref","first-page":"790","DOI":"10.1038\/ki.2012.197","article-title":"The level of galactose-deficient IgA1 in the sera of patients with IgA nephropathy is associated with disease progression","volume":"82","author":"Zhao","year":"2012","journal-title":"Kidney Int"},{"key":"10.1016\/j.ekir.2023.11.003_bib7","doi-asserted-by":"crossref","first-page":"1579","DOI":"10.1681\/ASN.2012010053","article-title":"Autoantibodies targeting galactose-deficient IgA1 associate with progression of IgA nephropathy","volume":"23","author":"Berthoux","year":"2012","journal-title":"J\u00a0Am Soc Nephrol"},{"key":"10.1016\/j.ekir.2023.11.003_bib8","article-title":"Galactose-deficient IgA1 and the corresponding IgG autoantibodies predict IgA nephropathy progression","volume":"14","author":"Maixnerova","year":"2019","journal-title":"PLoS One"},{"key":"10.1016\/j.ekir.2023.11.003_bib9","doi-asserted-by":"crossref","first-page":"486","DOI":"10.1016\/S0272-6386(03)00743-1","article-title":"IgA1 molecules produced by tonsillar lymphocytes are under-O-glycosylated in IgA nephropathy","volume":"42","author":"Horie","year":"2003","journal-title":"Am J Kidney Dis"},{"key":"10.1016\/j.ekir.2023.11.003_bib10","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1016\/j.clim.2010.05.009","article-title":"Differential expression of glycogenes in tonsillar B lymphocytes in association with proteinuria and renal dysfunction in IgA nephropathy","volume":"136","author":"Inoue","year":"2010","journal-title":"Clin Immunol"},{"key":"10.1016\/j.ekir.2023.11.003_bib11","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0089707","article-title":"Changes in nephritogenic serum galactose-deficient IgA1 in IgA nephropathy following tonsillectomy and steroid therapy","volume":"9","author":"Nakata","year":"2014","journal-title":"PLoS One"},{"key":"10.1016\/j.ekir.2023.11.003_bib12","doi-asserted-by":"crossref","first-page":"1227","DOI":"10.1681\/ASN.2016050496","article-title":"Toll-like receptor 9 stimulation induces aberrant expression of a proliferation-inducing ligand by tonsillar germinal center B cells in IgA nephropathy","volume":"28","author":"Muto","year":"2017","journal-title":"J\u00a0Am Soc Nephrol"},{"key":"10.1016\/j.ekir.2023.11.003_bib13","doi-asserted-by":"crossref","DOI":"10.1001\/jamanetworkopen.2019.4772","article-title":"Association between tonsillectomy and outcomes in patients with immunoglobulin A nephropathy","volume":"2","author":"Hirano","year":"2019","journal-title":"JAMA Netw Open"},{"key":"10.1016\/j.ekir.2023.11.003_bib14","doi-asserted-by":"crossref","first-page":"1301","DOI":"10.2215\/CJN.00310108","article-title":"Effect of tonsillectomy plus steroid pulse therapy on clinical remission of IgA nephropathy: a controlled study","volume":"3","author":"Komatsu","year":"2008","journal-title":"Clin J Am Soc Nephrol"},{"key":"10.1016\/j.ekir.2023.11.003_bib15","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1038\/ng.787","article-title":"Genome-wide association study identifies susceptibility loci for IgA nephropathy","volume":"43","author":"Gharavi","year":"2011","journal-title":"Nat Genet"},{"key":"10.1016\/j.ekir.2023.11.003_bib16","doi-asserted-by":"crossref","first-page":"6859","DOI":"10.1038\/s41467-022-34456-6","article-title":"Genetic regulation of serum IgA levels and susceptibility to common immune, infectious, kidney, and cardio-metabolic traits","volume":"13","author":"Liu","year":"2022","journal-title":"Nat Commun"},{"key":"10.1016\/j.ekir.2023.11.003_bib17","doi-asserted-by":"crossref","first-page":"1091","DOI":"10.1038\/s41588-023-01422-x","article-title":"Genome-wide association analyses define pathogenic signaling pathways and prioritize drug targets for IgA nephropathy","volume":"55","author":"Kiryluk","year":"2023","journal-title":"Nat Genet"},{"key":"10.1016\/j.ekir.2023.11.003_bib18","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1136\/jmedgenet-2016-104304","article-title":"Genome-wide association study identifies variants in HORMAD2 associated with tonsillectomy","volume":"54","author":"Feenstra","year":"2017","journal-title":"J Med Genet"},{"key":"10.1016\/j.ekir.2023.11.003_bib19","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1089\/jir.2022.0039","article-title":"Cytokines and production of aberrantly O-glycosylated IgA1, the main autoantigen in IgA nephropathy","volume":"42","author":"Person","year":"2022","journal-title":"J\u00a0Interferon Cytokine Res"},{"key":"10.1016\/j.ekir.2023.11.003_bib20","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1159\/000505748","article-title":"Leukemia inhibitory factor signaling enhances production of galactose-deficient IgA1 in IgA nephropathy","volume":"6","author":"Yamada","year":"2020","journal-title":"Kidney Dis (Basel)"},{"key":"10.1016\/j.ekir.2023.11.003_bib21","doi-asserted-by":"crossref","first-page":"973","DOI":"10.2215\/CJN.11010919","article-title":"JAK-STAT Activity in peripheral blood cells and kidney tissue in IgA nephropathy","volume":"15","author":"Tao","year":"2020","journal-title":"Clin J Am Soc Nephrol"},{"key":"10.1016\/j.ekir.2023.11.003_bib22","doi-asserted-by":"crossref","first-page":"1342","DOI":"10.1172\/JCI110886","article-title":"Immunoglobulin A nephropathy. Quantitative immunohistomorphometry of the tonsillar plasma cells evidences an inversion of the immunoglobulin A versus immunoglobulin G secreting cell balance","volume":"71","author":"Bene","year":"1983","journal-title":"J\u00a0Clin Invest"},{"key":"10.1016\/j.ekir.2023.11.003_bib23","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1111\/j.1365-3083.1988.tb02362.x","article-title":"Tonsillar distribution of IgA and IgG immunocytes and production of IgA subclasses and J chain in tonsillitis vary with the presence or absence of IgA nephropathy","volume":"27","author":"Nagy","year":"1988","journal-title":"Scand J Immunol"},{"key":"10.1016\/j.ekir.2023.11.003_bib24","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1016\/j.clim.2007.11.003","article-title":"Increase in B-cell-activation factor (BAFF) and IFN-\u03b3 productions by tonsillar mononuclear cells stimulated with deoxycytidyl-deoxyguanosine oligodeoxynucleotides (CpG-ODN) in patients with IgA nephropathy","volume":"126","author":"Goto","year":"2008","journal-title":"Clin Immunol"},{"key":"10.1016\/j.ekir.2023.11.003_bib25","doi-asserted-by":"crossref","DOI":"10.1016\/j.cellimm.2019.103925","article-title":"A\u00a0proliferation-inducing ligand (APRIL) induced hyper-production of IgA from tonsillar mononuclear cells in patients with IgA nephropathy","volume":"341","author":"Takahara","year":"2019","journal-title":"Cell Immunol"},{"key":"10.1016\/j.ekir.2023.11.003_bib26","first-page":"629","article-title":"IgA1-secreting cell lines from patients with IgA nephropathy produce aberrantly glycosylated IgA1","volume":"118","author":"Suzuki","year":"2008","journal-title":"J\u00a0Clin Invest"},{"key":"10.1016\/j.ekir.2023.11.003_bib27","doi-asserted-by":"crossref","first-page":"1194","DOI":"10.1016\/j.ekir.2017.07.002","article-title":"Inhibition of STAT3 signaling reduces IgA1 autoantigen production in IgA nephropathy","volume":"2","author":"Yamada","year":"2017","journal-title":"Kidney Int Rep"},{"key":"10.1016\/j.ekir.2023.11.003_bib28","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1006\/meth.2001.1262","article-title":"Analysis of relative gene expression data using real-time quantitative PCR and the 2-\u0394\u0394 CT method","volume":"25","author":"Livak","year":"2001","journal-title":"Methods"},{"key":"10.1016\/j.ekir.2023.11.003_bib29","doi-asserted-by":"crossref","first-page":"736","DOI":"10.1053\/ajkd.2001.27690","article-title":"Tonsillectomy and steroid pulse therapy significantly impact on clinical remission in patients with IgA nephropathy","volume":"38","author":"Hotta","year":"2001","journal-title":"Am J Kidney Dis"},{"key":"10.1016\/j.ekir.2023.11.003_bib30","doi-asserted-by":"crossref","first-page":"1546","DOI":"10.1093\/ndt\/gfu020","article-title":"A\u00a0multicenter randomized controlled trial of tonsillectomy combined with steroid pulse therapy in patients with immunoglobulin A nephropathy","volume":"29","author":"Kawamura","year":"2014","journal-title":"Nephrol Dial Transplant"},{"key":"10.1016\/j.ekir.2023.11.003_bib31","doi-asserted-by":"crossref","first-page":"S1","DOI":"10.1016\/j.kint.2021.05.021","article-title":"KDIGO 2021 Clinical practice guideline for the management of glomerular diseases","volume":"100","year":"2021","journal-title":"Kidney Int"},{"key":"10.1016\/j.ekir.2023.11.003_bib32","doi-asserted-by":"crossref","first-page":"1791","DOI":"10.1681\/ASN.2010010076","article-title":"HLA has strongest association with IgA nephropathy in genome-wide analysis","volume":"21","author":"Feehally","year":"2010","journal-title":"J\u00a0Am Soc Nephrol"},{"key":"10.1016\/j.ekir.2023.11.003_bib33","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1038\/ng.1047","article-title":"A\u00a0genome-wide association study in Han Chinese identifies multiple susceptibility loci for IgA nephropathy","volume":"44","author":"Yu","year":"2011","journal-title":"Nat Genet"},{"key":"10.1016\/j.ekir.2023.11.003_bib34","doi-asserted-by":"crossref","first-page":"3991","DOI":"10.1172\/JCI45563","article-title":"Mice overexpressing BAFF develop a commensal flora-dependent, IgA-associated nephropathy","volume":"121","author":"McCarthy","year":"2011","journal-title":"J\u00a0Clin Invest"},{"key":"10.1016\/j.ekir.2023.11.003_bib35","doi-asserted-by":"crossref","first-page":"562","DOI":"10.1016\/j.kint.2023.06.018","article-title":"MTMR3 risk alleles enhance Toll like receptor 9-induced IgA immunity in IgA nephropathy","volume":"104","author":"Wang","year":"2023","journal-title":"Kidney Int"},{"key":"10.1016\/j.ekir.2023.11.003_bib36","doi-asserted-by":"crossref","first-page":"5330","DOI":"10.1074\/jbc.M113.512277","article-title":"Cytokines alter IgA1 O-glycosylation by dysregulating C1GalT1 and ST6GalNAc-II enzymes","volume":"289","author":"Suzuki","year":"2014","journal-title":"J\u00a0Biol Chem"},{"key":"10.1016\/j.ekir.2023.11.003_bib37","doi-asserted-by":"crossref","first-page":"722","DOI":"10.1038\/nature07537","article-title":"A\u00a0human natural killer cell subset provides an innate source of IL-22 for mucosal immunity","volume":"457","author":"Cella","year":"2009","journal-title":"Nature"},{"key":"10.1016\/j.ekir.2023.11.003_bib38","doi-asserted-by":"crossref","first-page":"12737","DOI":"10.1073\/pnas.0705577104","article-title":"An unusual cytokine: Ig-domain interaction revealed in the crystal structure of leukemia inhibitory factor (LIF) in complex with the LIF receptor","volume":"104","author":"Huyton","year":"2007","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.ekir.2023.11.003_bib39","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1016\/S1097-2765(03)00365-4","article-title":"Convergent mechanisms for recognition of divergent cytokines by the shared signaling receptor gp130","volume":"12","author":"Boulanger","year":"2003","journal-title":"Mol Cell"},{"key":"10.1016\/j.ekir.2023.11.003_bib40","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1038\/s41586-021-03819-2","article-title":"Highly accurate protein structure prediction with AlphaFold","volume":"596","author":"Jumper","year":"2021","journal-title":"Nature"},{"key":"10.1016\/j.ekir.2023.11.003_bib41","doi-asserted-by":"crossref","first-page":"21214","DOI":"10.1074\/jbc.C110.129502","article-title":"Crystal structure of the entire ectodomain of gp130: insights into the molecular assembly of the tall cytokine receptor complexes","volume":"285","author":"Xu","year":"2010","journal-title":"J\u00a0Biol Chem"},{"key":"10.1016\/j.ekir.2023.11.003_bib42","doi-asserted-by":"crossref","DOI":"10.1126\/sciadv.ade4395","article-title":"Structural insights into the assembly of gp130 family cytokine signaling complexes","volume":"9","author":"Zhou","year":"2023","journal-title":"Sci Adv"},{"key":"10.1016\/j.ekir.2023.11.003_bib43","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.38089","article-title":"Receptor-mediated dimerization of JAK2 FERM domains is required for JAK2 activation","volume":"7","author":"Ferrao","year":"2018","journal-title":"eLife"},{"key":"10.1016\/j.ekir.2023.11.003_bib44","doi-asserted-by":"crossref","first-page":"754","DOI":"10.1038\/nsmb.2348","article-title":"Crystal structures of the JAK2 pseudokinase domain and the pathogenic mutant V617F","volume":"19","author":"Bandaranayake","year":"2012","journal-title":"Nat Struct Mol Biol"},{"key":"10.1016\/j.ekir.2023.11.003_bib45","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1021\/jm1011319","article-title":"Discovery of 5-chloro-N2\u2212[(1S)-1-(5-fluoropyrimidin-2-yl)ethyl]-N4-(5-methyl-1H-pyrazol-3-yl)pyrimidine-2,4-diamine (AZD1480) as a novel inhibitor of the Jak\/Stat pathway","volume":"54","author":"Ioannidis","year":"2011","journal-title":"J Med Chem"},{"key":"10.1016\/j.ekir.2023.11.003_bib46","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1126\/science.abn8933","article-title":"Structure of a Janus kinase cytokine receptor complex reveals the basis for dimeric activation","volume":"376","author":"Glassman","year":"2022","journal-title":"Science"},{"key":"10.1016\/j.ekir.2023.11.003_bib47","doi-asserted-by":"crossref","first-page":"W296","DOI":"10.1093\/nar\/gky427","article-title":"SWISS-MODEL: homology modelling of protein structures and complexes","volume":"46","author":"Waterhouse","year":"2018","journal-title":"Nucleic Acids Res"},{"key":"10.1016\/j.ekir.2023.11.003_bib48","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1038\/324073a0","article-title":"Complementary DNA for a novel human interleukin (BSF-2) that induces B lymphocytes to produce immunoglobulin","volume":"324","author":"Hirano","year":"1986","journal-title":"Nature"},{"key":"10.1016\/j.ekir.2023.11.003_bib49","doi-asserted-by":"crossref","first-page":"6177","DOI":"10.1128\/JVI.73.7.6177-6181.1999","article-title":"A\u00a0rhesus macaque Rhadinovirus related to Kaposi\u2019s sarcoma-associated herpesvirus\/human herpesvirus 8 encodes a functional homologue of interleukin-6","volume":"73","author":"Kaleeba","year":"1999","journal-title":"J\u00a0Virol"},{"key":"10.1016\/j.ekir.2023.11.003_bib50","doi-asserted-by":"crossref","first-page":"839","DOI":"10.1128\/jvi.71.1.839-842.1997","article-title":"Human herpesvirus 8 encodes a homolog of interleukin-6","volume":"71","author":"Neipel","year":"1997","journal-title":"J\u00a0Virol"},{"key":"10.1016\/j.ekir.2023.11.003_bib51","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1038\/nm0397-287","article-title":"Kaposi\u2019s sarcoma-associated human herpesvirus-8 encodes homologues of macrophage inflammatory protein-1 and interleukin-6","volume":"3","author":"Nicholas","year":"1997","journal-title":"Nat Med"},{"key":"10.1016\/j.ekir.2023.11.003_bib52","doi-asserted-by":"crossref","first-page":"2101","DOI":"10.1126\/science.1083901","article-title":"Hexameric structure and assembly of the interleukin-6\/IL-6 \u03b1-receptor\/gp130 complex","volume":"300","author":"Boulanger","year":"2003","journal-title":"Science"},{"key":"10.1016\/j.ekir.2023.11.003_bib53","doi-asserted-by":"crossref","first-page":"7512","DOI":"10.1073\/pnas.87.19.7512","article-title":"Molecular cloning of a cDNA encoding interleukin 11, a stromal cell-derived lymphopoietic and hematopoietic cytokine","volume":"87","author":"Paul","year":"1990","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.ekir.2023.11.003_bib54","first-page":"2847","article-title":"Molecular cloning, sequence analysis, and functional expression of a novel growth regulator, oncostatin M","volume":"9","author":"Malik","year":"1989","journal-title":"Mol Cell Biol"},{"key":"10.1016\/j.ekir.2023.11.003_bib55","doi-asserted-by":"crossref","first-page":"2225","DOI":"10.4049\/jimmunol.172.4.2225","article-title":"WSX-1 and glycoprotein 130 constitute a signal-transducing receptor for IL-27","volume":"172","author":"Pflanz","year":"2004","journal-title":"J\u00a0Immunol"},{"key":"10.1016\/j.ekir.2023.11.003_bib56","first-page":"290","article-title":"The composition and signaling of the IL-35 receptor are unconventional","volume":"13","author":"Collison","year":"2012","journal-title":"Nat\u00a0Immunol"},{"key":"10.1016\/j.ekir.2023.11.003_bib57","doi-asserted-by":"crossref","first-page":"542","DOI":"10.1016\/j.immuni.2012.03.014","article-title":"JAK and STAT signaling molecules in immunoregulation and immune-mediated disease","volume":"36","author":"O\u2019Shea","year":"2012","journal-title":"Immunity"},{"key":"10.1016\/j.ekir.2023.11.003_bib58","doi-asserted-by":"crossref","first-page":"1187","DOI":"10.1038\/ng.3118","article-title":"Discovery of new risk loci for IgA nephropathy implicates genes involved in immunity against intestinal pathogens","volume":"46","author":"Kiryluk","year":"2014","journal-title":"Nat Genet"}],"container-title":["Kidney International Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2468024923015796?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2468024923015796?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,11]],"date-time":"2025-11-11T03:50:06Z","timestamp":1762833006000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2468024923015796"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,2]]},"references-count":58,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2024,2]]}},"alternative-id":["S2468024923015796"],"URL":"https:\/\/doi.org\/10.1016\/j.ekir.2023.11.003","relation":{},"ISSN":["2468-0249"],"issn-type":[{"value":"2468-0249","type":"print"}],"subject":[],"published":{"date-parts":[[2024,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"LIF\/JAK2\/STAT1 Signaling Enhances Production of Galactose-Deficient IgA1 by IgA1-Producing Cell Lines Derived From Tonsils of Patients With IgA Nephropathy","name":"articletitle","label":"Article Title"},{"value":"Kidney International Reports","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ekir.2023.11.003","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 International Society of Nephrology. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}