{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T20:08:19Z","timestamp":1790280499418,"version":"4.1.0"},"reference-count":47,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,12,4]],"date-time":"2024-12-04T00:00:00Z","timestamp":1733270400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001659","name":"German Research Foundation","doi-asserted-by":"publisher","award":["RE 1723\/2-3"],"award-info":[{"award-number":["RE 1723\/2-3"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001659","name":"German Research Foundation","doi-asserted-by":"publisher","award":["HO 2583\/8-3"],"award-info":[{"award-number":["HO 2583\/8-3"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001659","name":"German Research Foundation","doi-asserted-by":"publisher","award":["RI 3503\/3-1"],"award-info":[{"award-number":["RI 3503\/3-1"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005713","name":"Technische Universit\u00e4t M\u00fcnchen","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005713","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["kireports.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Kidney International Reports"],"published-print":{"date-parts":[[2025,3]]},"DOI":"10.1016\/j.ekir.2024.12.006","type":"journal-article","created":{"date-parts":[[2024,12,9]],"date-time":"2024-12-09T19:38:28Z","timestamp":1733773108000},"page":"877-891","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"title":["Trio Exome Sequencing in VACTERL Association"],"prefix":"10.1016","volume":"10","author":[{"given":"Jasmina","family":"\u0106omi\u0107","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erik","family":"Tilch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7503-5801","authenticated-orcid":false,"given":"Korbinian M.","family":"Riedhammer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Melanie","family":"Brugger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Theresa","family":"Brunet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katharina","family":"Eyring","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katharina","family":"Vill","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silke","family":"Redler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Velibor","family":"Tasic","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eberhard","family":"Schmiedeke","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frank-Mattias","family":"Sch\u00e4fer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nora","family":"Abazi-Emini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ekkehart","family":"Jenetzky","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicole","family":"Schwarzer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anke","family":"Widenmann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"Lacher","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Zech","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sabine","family":"Grasshoff-Derr","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michaela","family":"Ge\u00dfner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carmen","family":"Kabs","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barbara","family":"Seitz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andreas C.","family":"Heydweiller","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oliver","family":"Muensterer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B\u00e4rbel","family":"Lange-Sperandio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Udo","family":"Rolle","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johannes","family":"Schumacher","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthias C.","family":"Braunisch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Riccardo","family":"Berutti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heiko","family":"Reutter","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7917-7129","authenticated-orcid":false,"given":"Julia","family":"Hoefele","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ekir.2024.12.006_bib1","doi-asserted-by":"crossref","first-page":"440","DOI":"10.1002\/ajmg.c.31664","article-title":"The etiology of VACTERL association: current knowledge and hypotheses","volume":"178","author":"Solomon","year":"2018","journal-title":"Am J Med Genet C"},{"key":"10.1016\/j.ekir.2024.12.006_bib2","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1186\/1750-1172-6-56","article-title":"VACTERL \/VATER Association","volume":"6","author":"Solomon","year":"2011","journal-title":"Orphanet J Rare Dis"},{"key":"10.1016\/j.ekir.2024.12.006_bib3","doi-asserted-by":"crossref","first-page":"3784","DOI":"10.1002\/ajmg.a.62447","article-title":"Exome survey of individuals affected by VATER\/VACTERL with renal phenotypes identifies phenocopies and novel candidate genes","volume":"185","author":"Kolvenbach","year":"2021","journal-title":"Am J Med Genet A"},{"key":"10.1016\/j.ekir.2024.12.006_bib4","doi-asserted-by":"crossref","first-page":"1495","DOI":"10.1002\/bdr2.1773","article-title":"Maternal risk associated with the VACTERL association: A case-control study","volume":"112","author":"van de Putte","year":"2020","journal-title":"Birth Defects Res"},{"key":"10.1016\/j.ekir.2024.12.006_bib5","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1053\/jpsu.2001.20722","article-title":"Murine models of VACTERL syndrome: role of sonic hedgehog signaling pathway","volume":"36","author":"Kim","year":"2001","journal-title":"J\u00a0Pediatr Surg"},{"key":"10.1016\/j.ekir.2024.12.006_bib6","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1016\/S0022-3476(73)80024-1","article-title":"The VATER association. Vertebral defects, Anal atresia, T-E fistula with esophageal atresia, Radial and Renal dysplasia: a spectrum of associated defects","volume":"82","author":"Quan","year":"1973","journal-title":"J\u00a0Pediatr"},{"key":"10.1016\/j.ekir.2024.12.006_bib7","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1038\/1711","article-title":"Essential function of Gli2 and Gli3 in the formation of lung, trachea and oesophagus","volume":"20","author":"Motoyama","year":"1998","journal-title":"Nat Genet"},{"key":"10.1016\/j.ekir.2024.12.006_bib8","doi-asserted-by":"crossref","first-page":"544","DOI":"10.1056\/NEJMoa1616361","article-title":"NAD deficiency, congenital malformations, and niacin supplementation","volume":"377","author":"Shi","year":"2017","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.ekir.2024.12.006_bib9","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1111\/j.1741-4520.2011.00354.x","article-title":"Novel association of VACTERL, neural tube defect and crossed renal ectopia: sonic hedgehog signaling: a point of coherence?","volume":"52","author":"Vaze","year":"2012","journal-title":"Congenit Anom (Kyoto)"},{"key":"10.1016\/j.ekir.2024.12.006_bib10","doi-asserted-by":"crossref","first-page":"1063","DOI":"10.1002\/bdr2.1042","article-title":"Array-based molecular karyotyping in 115 VATER\/VACTERL and VATER\/VACTERL-like patients identifies disease-causing copy number variations","volume":"109","author":"Zhang","year":"2017","journal-title":"Birth Defects Res"},{"key":"10.1016\/j.ekir.2024.12.006_bib11","doi-asserted-by":"crossref","DOI":"10.1038\/ncomms15824","article-title":"Genetic diagnosis of Mendelian disorders via RNA sequencing","volume":"8","author":"Kremer","year":"2017","journal-title":"Nat Commun"},{"key":"10.1016\/j.ekir.2024.12.006_bib12","doi-asserted-by":"crossref","first-page":"962","DOI":"10.1038\/gim.2014.66","article-title":"Accurate mitochondrial DNA sequencing using off-target reads provides a single test to identify pathogenic point mutations","volume":"16","author":"Griffin","year":"2014","journal-title":"Genet Med"},{"key":"10.1016\/j.ekir.2024.12.006_bib13","doi-asserted-by":"crossref","first-page":"2747","DOI":"10.1093\/bioinformatics\/bts526","article-title":"A\u00a0robust model for read count data in exome sequencing experiments and implications for copy number variant calling","volume":"28","author":"Plagnol","year":"2012","journal-title":"Bioinformatics"},{"key":"10.1016\/j.ekir.2024.12.006_bib14","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1038\/ng.2898","article-title":"Mutation-dependent recessive inheritance of NPHS2-associated steroid-resistant nephrotic syndrome","volume":"46","author":"Tory","year":"2014","journal-title":"Nat Genet"},{"key":"10.1016\/j.ekir.2024.12.006_bib15","doi-asserted-by":"crossref","first-page":"1854","DOI":"10.1002\/humu.23660","article-title":"The mutation-dependent pathogenicity of NPHS2 p.R229Q: a guide for clinical assessment","volume":"39","author":"Miko","year":"2018","journal-title":"Hum Mutat"},{"key":"10.1016\/j.ekir.2024.12.006_bib16","doi-asserted-by":"crossref","first-page":"1517","DOI":"10.1002\/humu.23626","article-title":"Recommendations for interpreting the loss of function PVS1 ACMG\/AMP variant criterion","volume":"39","author":"Abou Tayoun","year":"2018","journal-title":"Hum Mutat"},{"key":"10.1016\/j.ekir.2024.12.006_bib17","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1097\/GIM.0b013e3182217a3a","article-title":"American College of Medical Genetics standards and guidelines for interpretation and reporting of postnatal constitutional copy number variants","volume":"13","author":"Kearney","year":"2011","journal-title":"Genet Med"},{"key":"10.1016\/j.ekir.2024.12.006_bib18","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1038\/gim.2015.30","article-title":"Standards and guidelines for the interpretation of sequence variants: a joint consensus recommendation of the American College of Medical Genetics and Genomics and the Association for Molecular Pathology","volume":"17","author":"Richards","year":"2015","journal-title":"Genet Med"},{"key":"10.1016\/j.ekir.2024.12.006_bib19","unstructured":"Ellard S, Baple EL, Berry I, et\u00a0al. ACGS best practice guidelines for variant classification 2019. https:\/\/wwwacgs.uk.com\/media\/11631\/uk-practice-guidelines-for-variant-classification-v4-01-2020.pdf2019"},{"key":"10.1016\/j.ekir.2024.12.006_bib21","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1038\/nature19057","article-title":"Analysis of protein-coding genetic variation in 60,706 humans","volume":"536","author":"Lek","year":"2016","journal-title":"Nature"},{"key":"10.1016\/j.ekir.2024.12.006_bib22","doi-asserted-by":"crossref","first-page":"D886","DOI":"10.1093\/nar\/gky1016","article-title":"CADD: predicting the deleteriousness of variants throughout the human genome","volume":"47","author":"Rentzsch","year":"2019","journal-title":"Nucleic Acids Res"},{"key":"10.1016\/j.ekir.2024.12.006_bib23","doi-asserted-by":"crossref","DOI":"10.1126\/sciadv.abc9207","article-title":"Histone H3.3 beyond cancer: germline mutations in Histone 3 Family 3A and 3B cause a previously unidentified neurodegenerative disorder in 46 patients","volume":"6","author":"Bryant","year":"2020","journal-title":"Sci Adv"},{"key":"10.1016\/j.ekir.2024.12.006_bib24","article-title":"Human exome and mouse embryonic expression data implicate ZFHX3, TRPS1, and CHD7 in human esophageal atresia","volume":"15","author":"Zhang","year":"2020","journal-title":"PLoS One"},{"key":"10.1016\/j.ekir.2024.12.006_bib25","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1159\/000022918","article-title":"A\u00a0unified approach to adjusting association tests for population admixture with arbitrary pedigree structure and arbitrary missing marker information","volume":"50","author":"Rabinowitz","year":"2000","journal-title":"Hum Hered"},{"key":"10.1016\/j.ekir.2024.12.006_bib26","doi-asserted-by":"crossref","first-page":"1408","DOI":"10.1016\/j.kint.2019.08.027","article-title":"High-throughput sequencing contributes to the diagnosis of tubulopathies and\u00a0familial hypercalcemia hypocalciuria in adults","volume":"96","author":"Hureaux","year":"2019","journal-title":"Kidney Int"},{"key":"10.1016\/j.ekir.2024.12.006_bib27","doi-asserted-by":"crossref","DOI":"10.1101\/cshperspect.a028191","article-title":"Ciliopathies","volume":"9","author":"Braun","year":"2017","journal-title":"Cold Spring Harb Perspect Biol"},{"key":"10.1016\/j.ekir.2024.12.006_bib28","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1007\/s00467-022-05606-1","article-title":"A\u00a0clinical approach to tubulopathies in children and young adults","volume":"38","author":"Kermond","year":"2023","journal-title":"Pediatr Nephrol"},{"key":"10.1016\/j.ekir.2024.12.006_bib29","doi-asserted-by":"crossref","first-page":"3492","DOI":"10.1002\/ajmg.a.62976","article-title":"Exome sequencing efficacy and phenotypic expansions involving esophageal atresia\/tracheoesophageal fistula plus","volume":"188","author":"Sy","year":"2022","journal-title":"Am J Med Genet A"},{"key":"10.1016\/j.ekir.2024.12.006_bib30","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1038\/s41431-022-01255-y","article-title":"High molecular diagnostic yields and novel phenotypic expansions involving syndromic anorectal malformations","volume":"31","author":"Belanger Deloge","year":"2022","journal-title":"Eur J Hum Genet"},{"key":"10.1016\/j.ekir.2024.12.006_bib31","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1002\/ajmg.10400","article-title":"Genetic analysis of patients with the Saethre-Chotzen phenotype","volume":"110","author":"Chun","year":"2002","journal-title":"Am J Med Genet"},{"key":"10.1016\/j.ekir.2024.12.006_bib32","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1016\/j.ejmg.2011.02.002","article-title":"Microdeletions of chromosome 7p21, including TWIST1, associated with significant microcephaly, facial dysmorphism, and short stature","volume":"54","author":"Busche","year":"2011","journal-title":"Eur J Med Genet"},{"key":"10.1016\/j.ekir.2024.12.006_bib33","unstructured":"Gallagher ER, Ratisoontorn C, Cunningham ML. Saethre-Chotzen syndrome. In: Adam MP, Feldman J, Mirzaa GM, Pagon RA, et\u00a0al.,editors. GeneReviews [Internet]: Seattle (WA);1993-2024."},{"key":"10.1016\/j.ekir.2024.12.006_bib34","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1159\/000346192","article-title":"Considering the Embryopathogenesis of VACTERL association","volume":"4","author":"Stevenson","year":"2013","journal-title":"Mol Syndromol"},{"key":"10.1016\/j.ekir.2024.12.006_bib35","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1002\/(SICI)1096-8628(19960424)62:4<398::AID-AJMG13>3.0.CO;2-J","article-title":"VACTERL with the mitochondrial np 3243 point mutation","volume":"62","author":"Damian","year":"1996","journal-title":"Am J Med Genet"},{"key":"10.1016\/j.ekir.2024.12.006_bib36","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1002\/bdra.20768","article-title":"VACTERL association and mitochondrial dysfunction","volume":"91","author":"Solomon","year":"2011","journal-title":"Birth Defects Res A"},{"key":"10.1016\/j.ekir.2024.12.006_bib37","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1159\/000346301","article-title":"Mitochondrial factors and VACTERL association-related congenital malformations","volume":"4","author":"Siebel","year":"2013","journal-title":"Mol Syndromol"},{"key":"10.1016\/j.ekir.2024.12.006_bib38","doi-asserted-by":"crossref","first-page":"1330","DOI":"10.1002\/ijc.28768","article-title":"Multilayer-omics analysis of renal cell carcinoma, including the whole exome, methylome and transcriptome","volume":"135","author":"Arai","year":"2014","journal-title":"Int J Cancer"},{"key":"10.1016\/j.ekir.2024.12.006_bib39","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/bs.pmbts.2017.11.019","article-title":"Wnt signaling in kidney development and disease","volume":"153","author":"Wang","year":"2018","journal-title":"Prog Mol Biol Transl Sci"},{"key":"10.1016\/j.ekir.2024.12.006_bib40","doi-asserted-by":"crossref","first-page":"803","DOI":"10.1016\/j.ajhg.2017.09.026","article-title":"Mutations in GREB1L cause bilateral kidney agenesis in humans and mice","volume":"101","author":"De Tomasi","year":"2017","journal-title":"Am J Hum Genet"},{"key":"10.1016\/j.ekir.2024.12.006_bib42","doi-asserted-by":"crossref","first-page":"807","DOI":"10.1038\/ejhg.2011.39","article-title":"Genomic inflation factors under polygenic inheritance","volume":"19","author":"Yang","year":"2011","journal-title":"Eur J Hum Genet"},{"key":"10.1016\/j.ekir.2024.12.006_bib43","first-page":"405","article-title":"Cloning and characterization of a novel human gene encoding a zinc finger protein with 25 fingers","volume":"1489","author":"Li","year":"1999","journal-title":"BiochimBiophys Acta"},{"key":"10.1016\/j.ekir.2024.12.006_bib44","doi-asserted-by":"crossref","DOI":"10.3390\/biom9110692","article-title":"Notch signaling in kidney development, maintenance, and disease","volume":"9","author":"Mukherjee","year":"2019","journal-title":"Biomolecules"},{"key":"10.1016\/j.ekir.2024.12.006_bib45","doi-asserted-by":"crossref","first-page":"1622","DOI":"10.1093\/ndt\/gfu395","article-title":"Cell cycle control in the kidney","volume":"30","author":"Thomasova","year":"2015","journal-title":"Nephrol Dial Transplant"},{"key":"10.1016\/j.ekir.2024.12.006_bib46","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1016\/j.ajhg.2011.05.029","article-title":"Rare-variant association testing for sequencing data with the sequence kernel association test","volume":"89","author":"Wu","year":"2011","journal-title":"Am J Hum Genet"},{"key":"10.1016\/j.ekir.2024.12.006_bib47","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1016\/j.ajhg.2008.06.024","article-title":"Methods for detecting associations with rare variants for common diseases: application to analysis of sequence data","volume":"83","author":"Li","year":"2008","journal-title":"Am J Hum Genet"},{"key":"10.1016\/j.ekir.2024.12.006_bib48","article-title":"Utility of whole-exome sequencing for patients with multiple congenital anomalies with or without intellectual disability\/developmental delay in East Asia population","volume":"11","author":"Hsu","year":"2023","journal-title":"Mol Genet Genom Med"},{"key":"10.1016\/j.ekir.2024.12.006_bib49","doi-asserted-by":"crossref","first-page":"310","DOI":"10.3389\/fped.2020.00310","article-title":"A\u00a0genetics-first approach revealed monogenic disorders in patients with ARM and VACTERL anomalies","volume":"8","author":"van de Putte","year":"2020","journal-title":"Front Pediatr"}],"container-title":["Kidney International Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2468024924034053?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2468024924034053?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,8]],"date-time":"2025-11-08T18:48:41Z","timestamp":1762627721000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2468024924034053"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,3]]},"references-count":47,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2025,3]]}},"alternative-id":["S2468024924034053"],"URL":"https:\/\/doi.org\/10.1016\/j.ekir.2024.12.006","relation":{},"ISSN":["2468-0249"],"issn-type":[{"value":"2468-0249","type":"print"}],"subject":[],"published":{"date-parts":[[2025,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Trio Exome Sequencing in VACTERL Association","name":"articletitle","label":"Article Title"},{"value":"Kidney International Reports","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ekir.2024.12.006","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 International Society of Nephrology. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}