{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T23:19:00Z","timestamp":1791501540097,"version":"4.3.4"},"reference-count":29,"publisher":"Elsevier BV","issue":"8","license":[{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,5,21]],"date-time":"2025-05-21T00:00:00Z","timestamp":1747785600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100004702","name":"Baxter Healthcare Corp","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004702","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100011068","name":"Fondation Saint Luc","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100011068","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003386","name":"Soci\u00e9t\u00e9 de N\u00e9phrologie","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003386","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["kireports.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Kidney International Reports"],"published-print":{"date-parts":[[2025,8]]},"DOI":"10.1016\/j.ekir.2025.05.036","type":"journal-article","created":{"date-parts":[[2025,5,29]],"date-time":"2025-05-29T19:28:26Z","timestamp":1748546906000},"page":"2585-2596","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":10,"title":["The Double-Icodextrin Dose Randomized Controlled Trial of a Double Icodextrin Dose for Older Patients on Incremental Continuous Ambulatory Peritoneal Dialysis"],"prefix":"10.1016","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9242-7148","authenticated-orcid":false,"given":"Eric","family":"Goffin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cl\u00e9mence","family":"B\u00e9chade","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C\u00e9cile","family":"Courivaud","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catherine","family":"Bresson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fran\u00e7oise","family":"Heibel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Claude","family":"Stol\u00e9ar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0071-8402","authenticated-orcid":false,"given":"Karlien","family":"Fran\u00e7ois","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fatouma","family":"Tour\u00e9","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Didier","family":"Aguilera","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fran\u00e7ois","family":"Vrtovsnik","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bert","family":"Bammens","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7369-7812","authenticated-orcid":false,"given":"Michel","family":"Jadoul","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olivier","family":"Devuyst","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"Wilkie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aur\u00e9lie","family":"Bertrand","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thierry","family":"Lobbedez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric","family":"Goffin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bert","family":"Bammens","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joelle","family":"Nortier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philippe","family":"Bovy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Claude","family":"Stolear","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karlien","family":"Fran\u00e7ois","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olivier","family":"Mat","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fran\u00e7ois","family":"Vrtovsnik","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Didier","family":"Aguilera","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thierry","family":"Lobbedez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luc","family":"Frimat","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie-Fran\u00e7oise","family":"Nogier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandre","family":"Klein","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C\u00e9cile","family":"Courivaud","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marc","family":"Kribs","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fatouma","family":"Tour\u00e9","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Iain","family":"Macdougall","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"Wilkie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ekir.2025.05.036_bib1","doi-asserted-by":"crossref","first-page":"2052","DOI":"10.1016\/S0140-6736(18)31694-5","article-title":"Forecasting life expectancy, years of life lost, and all-cause and cause-specific mortality for 250 causes of death: reference and alternative scenarios for 2016\u201340 for 195 countries and territories","volume":"392","author":"Foreman","year":"2018","journal-title":"Lancet"},{"key":"10.1016\/j.ekir.2025.05.036_bib2","doi-asserted-by":"crossref","first-page":"gfae040","DOI":"10.1093\/ndt\/gfae040","article-title":"A comparison of the epidemiology of kidney replacement therapy between Europe and the United States: 2021 data of the ERA Registry and the USRDS","volume":"39","author":"Stel","year":"2024","journal-title":"Nephrol Dial Transplant"},{"key":"10.1016\/j.ekir.2025.05.036_bib3","doi-asserted-by":"crossref","unstructured":"Teitelbaum I. Peritoneal dialysis. N Engl J Med Ingelfinger JR, ed. 2021;385:1786-1795. https:\/\/doi.org\/10.1056\/NEJMra2100152","DOI":"10.1056\/NEJMra2100152"},{"key":"10.1016\/j.ekir.2025.05.036_bib4","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1038\/ki.2011.384","article-title":"Optimizing renal replacement therapy in older adults: a framework for making individualized decisions","volume":"82","author":"Tamura","year":"2012","journal-title":"Kidney Int"},{"key":"10.1016\/j.ekir.2025.05.036_bib5","doi-asserted-by":"crossref","first-page":"115","DOI":"10.2215\/CJN.0000000000000341","article-title":"How I treat elderly patients with kidney failure with peritoneal dialysis","volume":"19","author":"Wu","year":"2024","journal-title":"Clin J Am Soc Nephrol"},{"key":"10.1016\/j.ekir.2025.05.036_bib6","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1053\/j.ajkd.2022.07.004","article-title":"Peritoneal dialysis prescription and adequacy in clinical practice: core curriculum 2023","volume":"81","author":"Auguste","year":"2023","journal-title":"Am J Kidney Dis"},{"key":"10.1016\/j.ekir.2025.05.036_bib7","doi-asserted-by":"crossref","first-page":"779","DOI":"10.1038\/s41581-022-00623-7","article-title":"Epidemiology of peritoneal dialysis outcomes","volume":"18","author":"Bello","year":"2022","journal-title":"Nat Rev Nephrol"},{"key":"10.1016\/j.ekir.2025.05.036_bib8","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/j.kint.2019.01.017","article-title":"Dialysis initiation, modality choice, access, and prescription: conclusions from a kidney disease: improving global outcomes (KDIGO) controversies conference","volume":"96","author":"Chan","year":"2019","journal-title":"Kidney Int"},{"key":"10.1016\/j.ekir.2025.05.036_bib9","first-page":"CD007554","article-title":"Biocompatible dialysis fluids for peritoneal dialysis","volume":"2018","author":"Htay","year":"2018","journal-title":"Cochrane Database Syst Rev"},{"key":"10.1016\/j.ekir.2025.05.036_bib10","doi-asserted-by":"crossref","first-page":"1875","DOI":"10.1681\/ASN.2017080828","article-title":"Mechanisms of crystalloid versus colloid osmosis across the peritoneal membrane","volume":"29","author":"Morelle","year":"2018","journal-title":"J Am Soc Nephrol"},{"key":"10.1016\/j.ekir.2025.05.036_bib11","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1016\/S0140-6736(87)90764-1","article-title":"Ultrafiltration with an isosmotic solution during long peritoneal dialysis exhanges","volume":"330","author":"Mistry","year":"1987","journal-title":"Lancet"},{"key":"10.1016\/j.ekir.2025.05.036_bib12","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1002\/pds.4412","article-title":"Icodextrin reduces the risk of congestive heart failure in peritoneal dialysis patients","volume":"27","author":"Wang","year":"2018","journal-title":"Pharmacoepidemiol Drug Saf"},{"key":"10.1016\/j.ekir.2025.05.036_bib13","doi-asserted-by":"crossref","first-page":"862","DOI":"10.1053\/ajkd.2002.32009","article-title":"Efficacy and safety of a 7.5% icodextrin peritoneal dialysis solution in patients treated with automated peritoneal dialysis","volume":"39","author":"Plum","year":"2002","journal-title":"Am J Kidney Dis"},{"key":"10.1016\/j.ekir.2025.05.036_bib14","doi-asserted-by":"crossref","first-page":"872","DOI":"10.34067\/KID.0006922021","article-title":"International icodextrin use and association with peritoneal membrane function, fluid removal, patient and technique survival","volume":"3","author":"Davies","year":"2022","journal-title":"Kidney360"},{"key":"10.1016\/j.ekir.2025.05.036_bib15","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1016\/j.kint.2018.02.022","article-title":"NeutralpH and low-glucose degradation product dialysis fluids induce major early alterations of the peritoneal membrane in children on peritoneal dialysis","volume":"94","author":"Schaefer","year":"2018","journal-title":"Kidney Int"},{"key":"10.1016\/j.ekir.2025.05.036_bib16","doi-asserted-by":"crossref","first-page":"2408","DOI":"10.1681\/ASN.2021010080","article-title":"Acquired decline in ultrafiltration in peritoneal dialysis: the role of glucose","volume":"32","author":"Krediet","year":"2021","journal-title":"J Am Soc Nephrol"},{"key":"10.1016\/j.ekir.2025.05.036_bib17","doi-asserted-by":"crossref","first-page":"1570","DOI":"10.1056\/NEJMoa2034279","article-title":"AQP1 promoter variant, water transport, and outcomes in peritoneal dialysis","volume":"385","author":"Morelle","year":"2021","journal-title":"N Engl J Med"},{"key":"10.1016\/j.ekir.2025.05.036_bib18","doi-asserted-by":"crossref","first-page":"91","DOI":"10.3747\/pdi.2009.00175","article-title":"Double-dose icodextrin to increase ultrafiltration in PD patients with inadequate ultrafiltration","volume":"31","author":"Ballout","year":"2011","journal-title":"Perit Dial Int J Int Soc Perit Dial"},{"key":"10.1016\/j.ekir.2025.05.036_bib19","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1007\/s11255-010-9716-9","article-title":"Two icodextrin exchanges per day in peritoneal dialysis patients with ultrafiltration failure: one center\u2019s experience and review of the literature","volume":"43","author":"Dousdampanis","year":"2011","journal-title":"Int Urol Nephrol"},{"key":"10.1016\/j.ekir.2025.05.036_bib20","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1177\/089686080902900411","article-title":"Effects of twice-daily icodextrin administration on blood Pressure and left ventricular mass in patients on continuous ambulatory peritoneal dialysis","volume":"29","author":"Sav","year":"2009","journal-title":"Perit Dial Int J Int Soc Perit Dial"},{"key":"10.1016\/j.ekir.2025.05.036_bib21","doi-asserted-by":"crossref","first-page":"352","DOI":"10.1177\/0896860820982218","article-title":"ISPD recommendations for the evaluation of peritoneal membrane dysfunction in adults: classification, measurement, interpretation and rationale for intervention","volume":"41","author":"Morelle","year":"2021","journal-title":"Perit Dial Int J Int Soc Perit Dial"},{"key":"10.1016\/j.ekir.2025.05.036_bib22","doi-asserted-by":"crossref","first-page":"861","DOI":"10.2215\/CJN.16341221","article-title":"Variation in peritoneal dialysis time on therapy by country: results from the peritoneal dialysis outcomes and practice patterns study","volume":"17","author":"Lambie","year":"2022","journal-title":"Clin J Am Soc Nephrol"},{"key":"10.1016\/j.ekir.2025.05.036_bib23","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1177\/08968608211036796","article-title":"Incremental peritoneal dialysis in incident end-stage kidney disease patients","volume":"42","author":"Yan","year":"2022","journal-title":"Perit Dial Int J Int Soc Perit Dial"},{"key":"10.1016\/j.ekir.2025.05.036_bib24","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1177\/0896860819895364","article-title":"International Society for peritoneal dialysis practice recommendations: prescribing high-quality goal-directed peritoneal dialysis","volume":"40","author":"Brown","year":"2020","journal-title":"Perit Dial Int J Int Soc Perit Dial"},{"key":"10.1016\/j.ekir.2025.05.036_bib25","doi-asserted-by":"crossref","first-page":"1085","DOI":"10.1093\/ndt\/17.6.1085","article-title":"Quantifying comorbidity in peritoneal dialysis patients and its relationship to other predictors of survival","volume":"17","author":"Davies","year":"2002","journal-title":"Nephrol Dial Transplant"},{"key":"10.1016\/j.ekir.2025.05.036_bib26","doi-asserted-by":"crossref","first-page":"570","DOI":"10.1093\/ckj\/sfz175","article-title":"The impact of volume overload on technique failure in incident peritoneal dialysis patients","volume":"14","author":"Vrtovsnik","year":"2021","journal-title":"Clin Kidney J"},{"key":"10.1016\/j.ekir.2025.05.036_bib27","doi-asserted-by":"crossref","first-page":"588","DOI":"10.1016\/S0140-6736(05)70800-X","article-title":"Aseptic peritonitis due to peptidoglycan contamination of pharmacopoeia standard dialysis solution","volume":"365","author":"Martis","year":"2005","journal-title":"Lancet"},{"key":"10.1016\/j.ekir.2025.05.036_bib28","doi-asserted-by":"crossref","first-page":"1258","DOI":"10.1038\/ki.2015.40","article-title":"Icodextrin skin rash incidence","volume":"87","author":"Biblaki","year":"2015","journal-title":"Kidney Int"},{"key":"10.1016\/j.ekir.2025.05.036_bib29","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1177\/089686080902900402","article-title":"Icodextrin metabolites in peritoneal dialysis","volume":"29","author":"Garc\u00eda\u2013L\u00f3pez","year":"2009","journal-title":"Perit Dial Int J Int Soc Perit Dial"}],"updated-by":[{"DOI":"10.1016\/j.ekir.2025.10.001","type":"erratum","label":"Erratum","source":"publisher","updated":{"date-parts":[[2025,10,16]],"date-time":"2025-10-16T00:00:00Z","timestamp":1760572800000}},{"DOI":"10.1016\/j.ekir.2025.10.001","type":"erratum","label":"Erratum","source":"publisher","updated":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000}}],"container-title":["Kidney International Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2468024925003390?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2468024925003390?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,12,6]],"date-time":"2025-12-06T03:15:52Z","timestamp":1764990952000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2468024925003390"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8]]},"references-count":29,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2025,8]]}},"alternative-id":["S2468024925003390"],"URL":"https:\/\/doi.org\/10.1016\/j.ekir.2025.05.036","relation":{},"ISSN":["2468-0249"],"issn-type":[{"value":"2468-0249","type":"print"}],"subject":[],"published":{"date-parts":[[2025,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The Double-Icodextrin Dose Randomized Controlled Trial of a Double Icodextrin Dose for Older Patients on Incremental Continuous Ambulatory Peritoneal Dialysis","name":"articletitle","label":"Article Title"},{"value":"Kidney International Reports","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ekir.2025.05.036","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"https:\/\/doi.org\/10.1016\/j.ekir.2025.06.013","name":"associatedlink","label":"CrossRef DOI link to the associated document"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 International Society of Nephrology. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}