{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T10:11:06Z","timestamp":1780481466892,"version":"3.54.1"},"reference-count":71,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,3,18]],"date-time":"2026-03-18T00:00:00Z","timestamp":1773792000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100012324","name":"University Hospitals","doi-asserted-by":"publisher","award":["S60307"],"award-info":[{"award-number":["S60307"]}],"id":[{"id":"10.13039\/100012324","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003130","name":"Fonds Wetenschappelijk Onderzoek","doi-asserted-by":"publisher","award":["1800923N"],"award-info":[{"award-number":["1800923N"]}],"id":[{"id":"10.13039\/501100003130","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003130","name":"Fonds Wetenschappelijk Onderzoek","doi-asserted-by":"publisher","award":["FWO 1196522N"],"award-info":[{"award-number":["FWO 1196522N"]}],"id":[{"id":"10.13039\/501100003130","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010648","name":"KU Leuven Hospital","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100010648","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004040","name":"KU Leuven","doi-asserted-by":"publisher","award":["C14\/19\/100"],"award-info":[{"award-number":["C14\/19\/100"]}],"id":[{"id":"10.13039\/501100004040","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["kireports.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Kidney International Reports"],"published-print":{"date-parts":[[2026,6]]},"DOI":"10.1016\/j.ekir.2026.106498","type":"journal-article","created":{"date-parts":[[2026,3,24]],"date-time":"2026-03-24T17:31:30Z","timestamp":1774373490000},"page":"106498","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Case-Control and Longitudinal Study of Sex Steroids in Male Patients with CKD Before and After Kidney Transplantation"],"prefix":"10.1016","volume":"11","author":[{"given":"Karel","family":"David","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nick","family":"Narinx","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bjorn","family":"Meijers","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leen","family":"Antonio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Henriette","family":"de Loor","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frank","family":"Claessens","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dirk","family":"Vanderschueren","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dirk","family":"Kuypers","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maarten","family":"Naesens","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brigitte","family":"Decallonne","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pieter","family":"Evenepoel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ekir.2026.106498_bib1","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1007\/s11154-016-9385-9","article-title":"Gonadal dysfunction in chronic kidney disease","volume":"18","author":"Palmer","year":"2017","journal-title":"Rev Endocr Metab Disord"},{"key":"10.1016\/j.ekir.2026.106498_bib2","article-title":"Testosterone deficiency and chronic kidney disease","volume":"37","author":"Zitzmann","year":"2024","journal-title":"J Clin Transl Endocrinol"},{"key":"10.1016\/j.ekir.2026.106498_bib3","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1093\/ndt\/gfq397","article-title":"Prevalence and clinical implications of testosterone deficiency in men with end-stage renal disease","volume":"26","author":"Carrero","year":"2011","journal-title":"Nephrol Dial Transplant"},{"key":"10.1016\/j.ekir.2026.106498_bib4","doi-asserted-by":"crossref","first-page":"1617","DOI":"10.2215\/CJN.10681210","article-title":"Endogenous testosterone, endothelial dysfunction, and cardiovascular events in men with nondialysis chronic kidney disease","volume":"6","author":"Yilmaz","year":"2011","journal-title":"Clin J Am Soc Nephrol"},{"key":"10.1016\/j.ekir.2026.106498_bib5","first-page":"496","article-title":"European Renal Osteodystrophy (EUROD) workgroup, an initiative of the CKD-MBD working group of the ERA-EDTA. Traditional and non-traditional risk factors for osteoporosis in CKD","volume":"108","author":"Jorgensen","year":"2021","journal-title":"Calcif Tissue Int"},{"key":"10.1016\/j.ekir.2026.106498_bib6","doi-asserted-by":"crossref","DOI":"10.1530\/EC-22-0061","article-title":"The role of serum testosterone and dehydroepiandrosterone sulfate in kidney function and clinical outcomes in chronic kidney disease: a systematic review and meta-analysis","volume":"11","author":"van der Burgh","year":"2022","journal-title":"Endocr Connect"},{"key":"10.1016\/j.ekir.2026.106498_bib7","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1681\/ASN.2008060664","article-title":"Low serum testosterone increases mortality risk among male dialysis patients","volume":"20","author":"Carrero","year":"2009","journal-title":"J Am Soc Nephrol"},{"key":"10.1016\/j.ekir.2026.106498_bib8","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1053\/j.ajkd.2014.03.010","article-title":"Serum testosterone levels and mortality in men with CKD stages 3\u20134","volume":"64","author":"Khurana","year":"2014","journal-title":"Am J Kidney Dis"},{"key":"10.1016\/j.ekir.2026.106498_bib9","doi-asserted-by":"crossref","first-page":"576","DOI":"10.1111\/cen.15206","article-title":"Androgen deficiency, associations and survival of men with Stage 4 and 5 chronic kidney disease: a cohort study","volume":"102","author":"De Silva","year":"2025","journal-title":"Clin Endocrinol (Oxf)"},{"key":"10.1016\/j.ekir.2026.106498_bib10","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1210\/edrv-6-2-151","article-title":"Hypothalamic-pituitary gonadal dysfunction in renal failure, dialysis and renal transplantation","volume":"6","author":"Handelsman","year":"1985","journal-title":"Endocr Rev"},{"key":"10.1016\/j.ekir.2026.106498_bib11","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1016\/j.semnephrol.2022.04.005","article-title":"Reproductive health in chronic kidney disease: the implications of sex and gender","volume":"42","author":"Dumanski","year":"2022","journal-title":"Semin Nephrol"},{"key":"10.1016\/j.ekir.2026.106498_bib12","doi-asserted-by":"crossref","first-page":"173","DOI":"10.21037\/tau.2018.07.16","article-title":"Male infertility in renal failure and transplantation","volume":"8","author":"Lundy","year":"2019","journal-title":"Transl Androl Urol"},{"key":"10.1016\/j.ekir.2026.106498_bib13","doi-asserted-by":"crossref","first-page":"624","DOI":"10.1111\/andr.70097","article-title":"The effects of kidney transplantation on sex hormones, sperm parameters, and fertility rate in males: a systematic review","volume":"14","author":"Hazir","year":"2025","journal-title":"Andrology"},{"key":"10.1016\/j.ekir.2026.106498_bib14","series-title":"Europe PMC","article-title":"Endocrinology of the male reproductive system and spermatogenesis","author":"O\u2019Donnell","year":"2000"},{"key":"10.1016\/j.ekir.2026.106498_bib15","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1007\/s00018-022-04562-1","article-title":"Role of sex hormone-binding globulin in the free hormone hypothesis and the relevance of free testosterone in androgen physiology","volume":"79","author":"Narinx","year":"2022","journal-title":"Cell Mol Life Sci"},{"key":"10.1016\/j.ekir.2026.106498_bib16","doi-asserted-by":"crossref","first-page":"3110","DOI":"10.1210\/jcem.83.9.5121","article-title":"Serum inhibin B as a marker of spermatogenesis","volume":"83","author":"Pierik","year":"1998","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.ekir.2026.106498_bib17","doi-asserted-by":"crossref","first-page":"E715","DOI":"10.1073\/pnas.1715035115","article-title":"Ibuprofen alters human testicular physiology to produce a state of compensated hypogonadism","volume":"115","author":"Kristensen","year":"2018","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.ekir.2026.106498_bib18","doi-asserted-by":"crossref","first-page":"1182","DOI":"10.2215\/CJN.07971109","article-title":"-Cresol and cardiovascular risk in mild-to-moderate kidney disease","volume":"5","author":"Meijers","year":"2010","journal-title":"Clin J Am Soc Nephrol"},{"key":"10.1016\/j.ekir.2026.106498_bib19","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1111\/j.1365-2605.2008.00879.x","article-title":"The European Male Ageing Study (EMAS): design, methods and recruitment","volume":"32","author":"Lee","year":"2009","journal-title":"Int J Androl"},{"key":"10.1016\/j.ekir.2026.106498_bib20","doi-asserted-by":"crossref","DOI":"10.1155\/2018\/7956951","article-title":"Free testosterone reflects metabolic as well as ovarian disturbances in subfertile oligomenorrheic women","volume":"2018","author":"Antonio","year":"2018","journal-title":"Int J Endocrinol"},{"key":"10.1016\/j.ekir.2026.106498_bib21","doi-asserted-by":"crossref","first-page":"8569","DOI":"10.1007\/s00216-013-7259-5","article-title":"Sensitive routine liquid chromatography-tandem mass spectrometry method for serum estradiol and estrone without derivatization","volume":"405","author":"Pauwels","year":"2013","journal-title":"Anal Bioanal Chem"},{"key":"10.1016\/j.ekir.2026.106498_bib22","doi-asserted-by":"crossref","first-page":"1810","DOI":"10.1210\/jc.2009-1796","article-title":"Characteristics of secondary, primary, and compensated hypogonadism in aging men: evidence from the European Male Ageing Study","volume":"95","author":"Tajar","year":"2010","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.ekir.2026.106498_bib23","doi-asserted-by":"crossref","first-page":"3666","DOI":"10.1210\/jcem.84.10.6079","article-title":"A critical evaluation of simple methods for the estimation of free testosterone in serum","volume":"84","author":"Vermeulen","year":"1999","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.ekir.2026.106498_bib24","doi-asserted-by":"crossref","first-page":"1737","DOI":"10.1056\/NEJMoa2102953","article-title":"New creatinine- and cystatin C-based equations to estimate GFR without race","volume":"385","author":"Inker","year":"2021","journal-title":"N Engl J Med"},{"key":"10.1016\/j.ekir.2026.106498_bib25","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1159\/000484992","article-title":"Impact of kidney transplantation on reproductive hormone levels in males: a longitudinal study","volume":"138","author":"Eckersten","year":"2018","journal-title":"Nephron"},{"key":"10.1016\/j.ekir.2026.106498_bib26","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1136\/pgmj.2006.045963","article-title":"Prevalence of hypogonadism in male patients with renal failure","volume":"82","author":"Albaaj","year":"2006","journal-title":"Postgrad Med J"},{"key":"10.1016\/j.ekir.2026.106498_bib27","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1111\/andr.12433","article-title":"Clinical and biochemical correlates of male hypogonadism in type 2 diabetes","volume":"6","author":"Herrero","year":"2018","journal-title":"Andrology"},{"key":"10.1016\/j.ekir.2026.106498_bib28","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1186\/s12610-015-0027-y","article-title":"Testosterone and gonadotropins but not SHBG vary with CKD stages in young and middle aged men","volume":"25","author":"Hylander","year":"2015","journal-title":"Basic Clin Androl"},{"key":"10.1016\/j.ekir.2026.106498_bib29","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1159\/000480302","article-title":"Association between testosterone and mortality risk among U.S. Males receiving dialysis","volume":"46","author":"Yu","year":"2017","journal-title":"Am J Nephrol"},{"key":"10.1016\/j.ekir.2026.106498_bib30","first-page":"135","article-title":"The association of decreased testosterone with atherosclerosis and inflammation in male predialysis patients with chronic kidney disease","volume":"32","author":"Aydemir","year":"2020","journal-title":"Clin Investig Arterioscler"},{"key":"10.1016\/j.ekir.2026.106498_bib31","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1530\/EJE-15-0359","article-title":"Prevalence of subnormal testosterone concentrations in men with type 2 diabetes and chronic kidney disease","volume":"173","author":"Dhindsa","year":"2015","journal-title":"Eur J Endocrinol"},{"key":"10.1016\/j.ekir.2026.106498_bib32","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1016\/j.ekir.2018.01.009","article-title":"Bioavailable testosterone is positively associated with bone mineral density in male kidney transplantation candidates","volume":"3","author":"J\u00f8rgensen","year":"2018","journal-title":"Kidney Int Rep"},{"key":"10.1016\/j.ekir.2026.106498_bib33","doi-asserted-by":"crossref","DOI":"10.3389\/fendo.2022.1000650","article-title":"Associations of endogenous androgens and sex hormone-binding globulin with kidney function and chronic kidney disease","volume":"13","author":"Lau","year":"2022","journal-title":"Front Endocrinol (Lausanne)"},{"key":"10.1016\/j.ekir.2026.106498_bib34","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1111\/cen.12656","article-title":"Sex steroids levels in chronic kidney disease and kidney transplant recipients: associations with disease severity and prediction of mortality","volume":"82","author":"Grossmann","year":"2015","journal-title":"Clin Endocrinol (Oxf)"},{"key":"10.1016\/j.ekir.2026.106498_bib35","doi-asserted-by":"crossref","first-page":"1245","DOI":"10.1056\/NEJM197706022962201","article-title":"The pituitary-testicular axis in men with chronic renal failure","volume":"296","author":"Holdsworth","year":"1977","journal-title":"N Engl J Med"},{"key":"10.1016\/j.ekir.2026.106498_bib36","first-page":"648","article-title":"Evidence for attenuation of hypothalamic gonadotropin-releasing hormone (GnRH) impulse strength with preservation of GnRH pulse frequency in men with chronic renal failure","volume":"76","author":"Veldhuis","year":"1993","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.ekir.2026.106498_bib37","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1053\/j.ackd.2004.07.004","article-title":"The hypothalamic-pituitary axis in men and women with chronic kidney disease","volume":"11","author":"Holley","year":"2004","journal-title":"Adv Chronic Kidney Dis"},{"key":"10.1016\/j.ekir.2026.106498_bib38","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1038\/ki.1997.109","article-title":"Circulating luteinizing hormone receptor inhibitor(s) in boys with chronic renal failure","volume":"51","author":"Dunkel","year":"1997","journal-title":"Kidney Int"},{"key":"10.1016\/j.ekir.2026.106498_bib39","doi-asserted-by":"crossref","first-page":"1271","DOI":"10.1089\/107999099312948","article-title":"Dose-dependent effects of recombinant human interleukin-6 on the pituitary-testicular axis","volume":"19","author":"Tsigos","year":"1999","journal-title":"J Interferon Cytokine Res"},{"key":"10.1016\/j.ekir.2026.106498_bib40","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1111\/j.1365-2265.1995.tb02669.x","article-title":"Age related changes in the pituitary-testicular axis in normal men; lower serum testosterone results from decreased bioactive LH drive","volume":"42","author":"Mitchell","year":"1995","journal-title":"Clin Endocrinol (Oxf)"},{"key":"10.1016\/j.ekir.2026.106498_bib41","doi-asserted-by":"crossref","first-page":"638","DOI":"10.2215\/CJN.01290214","article-title":"Insulin resistance in CKD","volume":"9","author":"Leyking","year":"2014","journal-title":"Clin J Am Soc Nephrol"},{"key":"10.1016\/j.ekir.2026.106498_bib42","doi-asserted-by":"crossref","first-page":"1184","DOI":"10.1016\/j.kint.2016.06.041","article-title":"Parathyroid hormone metabolism and signaling in health and chronic kidney disease","volume":"90","author":"Evenepoel","year":"2016","journal-title":"Kidney Int"},{"key":"10.1016\/j.ekir.2026.106498_bib43","doi-asserted-by":"crossref","first-page":"906","DOI":"10.3389\/fendo.2019.00906","article-title":"Hypogonadism and cryptorchidism","volume":"10","author":"Rodprasert","year":"2019","journal-title":"Front Endocrinol (Lausanne)"},{"key":"10.1016\/j.ekir.2026.106498_bib44","doi-asserted-by":"crossref","DOI":"10.3389\/fendo.2022.1016107","article-title":"The Leydig cell biomarker INSL3 as a predictor of age-related morbidity: findings from the EMAS cohort","volume":"13","author":"Ivell","year":"2022","journal-title":"Front Endocrinol (Lausanne)"},{"key":"10.1016\/j.ekir.2026.106498_bib45","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1210\/jc.2002-020408","article-title":"Testicular volume in relation to hormonal indices of gonadal function in community-dwelling elderly men","volume":"88","author":"Mahmoud","year":"2003","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.ekir.2026.106498_bib46","doi-asserted-by":"crossref","first-page":"735","DOI":"10.1159\/000064079","article-title":"Time course of serum prolactin and sex hormones following successful renal transplantation","volume":"92","author":"Saha","year":"2002","journal-title":"Nephron"},{"key":"10.1016\/j.ekir.2026.106498_bib47","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1007\/s11255-007-9277-8","article-title":"A prospective analysis of testicular androgenic function in recipients of a renal allograft","volume":"40","author":"Yadav","year":"2008","journal-title":"Int Urol Nephrol"},{"key":"10.1016\/j.ekir.2026.106498_bib48","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1007\/s12020-018-1543-2","article-title":"Rapid recovery of hypogonadism in male patients with end stage renal disease after renal transplantation","volume":"60","author":"Reinhardt","year":"2018","journal-title":"Endocrine"},{"key":"10.1016\/j.ekir.2026.106498_bib49","doi-asserted-by":"crossref","first-page":"1967","DOI":"10.21037\/tau-20-604","article-title":"Erectile function after kidney transplantation: a meta-analysis","volume":"9","author":"Kang","year":"2020","journal-title":"Transl Androl Urol"},{"key":"10.1016\/j.ekir.2026.106498_bib50","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1038\/s41443-021-00419-6","article-title":"Effects of renal transplantation on erectile dysfunction: a systematic review and meta-analysis","volume":"34","author":"Rahman","year":"2022","journal-title":"Int J Impot Res"},{"key":"10.1016\/j.ekir.2026.106498_bib51","doi-asserted-by":"crossref","first-page":"648","DOI":"10.7326\/0003-4819-104-5-648","article-title":"Reduction of serum testosterone levels during chronic glucocorticoid therapy","volume":"104","author":"MacAdams","year":"1986","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.ekir.2026.106498_bib52","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1111\/j.1432-2277.2006.00423.x","article-title":"Gonadal impact of target of rapamycin inhibitors (sirolimus and everolimus) in male patients: an overview","volume":"20","author":"Huyghe","year":"2007","journal-title":"Transpl Int"},{"key":"10.1016\/j.ekir.2026.106498_bib53","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1046\/j.1600-6135.2003.00279.x","article-title":"Testosterone concentrations and sirolimus in male renal transplant patients","volume":"4","author":"Fritsche","year":"2004","journal-title":"Am J Transplant"},{"key":"10.1016\/j.ekir.2026.106498_bib54","doi-asserted-by":"crossref","first-page":"1915","DOI":"10.1016\/j.transproceed.2005.04.004","article-title":"Gonadal function and immunosuppressive therapy after renal transplantation","volume":"37","author":"Tondolo","year":"2005","journal-title":"Transplant Proc"},{"key":"10.1016\/j.ekir.2026.106498_bib55","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1016\/j.transproceed.2003.11.017","article-title":"Effects of different calcineurin inhibitors on sex hormone levels in transplanted male patients","volume":"36","author":"Kantarci","year":"2004","journal-title":"Transplant Proc"},{"key":"10.1016\/j.ekir.2026.106498_bib56","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1007\/s40620-018-0513-3","article-title":"Testosterone in renal transplant patients: effect on body composition and clinical parameters","volume":"31","author":"Lofaro","year":"2018","journal-title":"J Nephrol"},{"key":"10.1016\/j.ekir.2026.106498_bib57","doi-asserted-by":"crossref","first-page":"149","DOI":"10.4103\/1008-682X.135124","article-title":"Male patients with terminal renal failure exhibit low serum levels of antiM\u00fcllerian hormone","volume":"17","author":"Eckersten","year":"2015","journal-title":"Asian J Androl"},{"key":"10.1016\/j.ekir.2026.106498_bib58","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1186\/2051-4190-24-11","article-title":"A prospective study in male recipients of kidney transplantation reveals divergent patterns for inhibin B and testosterone secretions","volume":"24","author":"Hamdi","year":"2014","journal-title":"Basic Clin Androl"},{"key":"10.1016\/j.ekir.2026.106498_bib59","doi-asserted-by":"crossref","first-page":"167","DOI":"10.3109\/01485019808994887","article-title":"Circulating levels of inhibin in hemodialysis males","volume":"41","author":"Sasagawa","year":"1998","journal-title":"Arch Androl"},{"key":"10.1016\/j.ekir.2026.106498_bib60","doi-asserted-by":"crossref","first-page":"2089","DOI":"10.1093\/humrep\/deg412","article-title":"History of febrile illness and variation in semen quality","volume":"18","author":"Carlsen","year":"2003","journal-title":"Hum Reprod"},{"key":"10.1016\/j.ekir.2026.106498_bib61","doi-asserted-by":"crossref","DOI":"10.3389\/fendo.2022.897029","article-title":"Mechanism of inflammatory associated impairment of sperm function, spermatogenesis and steroidogenesis","volume":"13","author":"Hasan","year":"2022","journal-title":"Front Endocrinol (Lausanne)"},{"key":"10.1016\/j.ekir.2026.106498_bib62","doi-asserted-by":"crossref","first-page":"1471","DOI":"10.1111\/j.1600-6143.2008.02267.x","article-title":"Sirolimus may reduce fertility in male renal transplant recipients","volume":"8","author":"Zuber","year":"2008","journal-title":"Am J Transplant"},{"key":"10.1016\/j.ekir.2026.106498_bib63","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1046\/j.1464-410X.2003.04323.x","article-title":"Effect of renal transplantation on sperm quality and sex hormone levels","volume":"92","author":"Akbari","year":"2003","journal-title":"BJU Int"},{"key":"10.1016\/j.ekir.2026.106498_bib64","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1046\/j.1464-410X.1996.14624.x","article-title":"Male reproductive function in uraemia: efficacy of haemodialysis and renal transplantation","volume":"78","author":"Prem","year":"1996","journal-title":"Br J Urol"},{"key":"10.1016\/j.ekir.2026.106498_bib65","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1111\/j.1439-0272.2009.00924.x","article-title":"Examination of the semen quality of patients with uraemia and renal transplant recipients in comparison with a control group","volume":"41","author":"Xu","year":"2009","journal-title":"Andrologia"},{"key":"10.1016\/j.ekir.2026.106498_bib66","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1053\/j.ackd.2004.07.008","article-title":"Outcomes associated with hypogonadism in men with chronic kidney disease","volume":"11","author":"Palmer","year":"2004","journal-title":"Adv Chronic Kidney Dis"},{"key":"10.1016\/j.ekir.2026.106498_bib67","doi-asserted-by":"crossref","first-page":"674","DOI":"10.1007\/s11914-018-0483-3","article-title":"Gonadal hormones in the pathogenesis and treatment of bone health in patients with chronic kidney disease: a systematic review and meta-analysis","volume":"16","author":"Aleksova","year":"2018","journal-title":"Curr Osteoporos Rep"},{"key":"10.1016\/j.ekir.2026.106498_bib68","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1093\/ndt\/gfr288","article-title":"Testosterone deficiency is a cause of anaemia and reduced responsiveness to erythropoiesis-stimulating agents in men with chronic kidney disease","volume":"27","author":"Carrero","year":"2012","journal-title":"Nephrol Dial Transplant"},{"key":"10.1016\/j.ekir.2026.106498_bib69","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1053\/j.ackd.2004.07.006","article-title":"Treatment of hypogonadism in men with chronic kidney disease","volume":"11","author":"Johansen","year":"2004","journal-title":"Adv Chronic Kidney Dis"},{"key":"10.1016\/j.ekir.2026.106498_bib70","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1111\/sdi.12318","article-title":"Diagnosis and treatment of low testosterone among patients with end-stage renal disease","volume":"28","author":"Bao","year":"2015","journal-title":"Semin Dial"},{"key":"10.1016\/j.ekir.2026.106498_bib71","doi-asserted-by":"crossref","first-page":"1069","DOI":"10.1177\/1557988317703207","article-title":"Sexual function and testosterone level in men with conservatively treated chronic kidney disease","volume":"11","author":"Fugl-Meyer","year":"2017","journal-title":"Am J Mens Health"}],"container-title":["Kidney International Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2468024926027300?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2468024926027300?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T09:23:23Z","timestamp":1780478603000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2468024926027300"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6]]},"references-count":71,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2026,6]]}},"alternative-id":["S2468024926027300"],"URL":"https:\/\/doi.org\/10.1016\/j.ekir.2026.106498","relation":{},"ISSN":["2468-0249"],"issn-type":[{"value":"2468-0249","type":"print"}],"subject":[],"published":{"date-parts":[[2026,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Case-Control and Longitudinal Study of Sex Steroids in Male Patients with CKD Before and After Kidney Transplantation","name":"articletitle","label":"Article Title"},{"value":"Kidney International Reports","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ekir.2026.106498","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Author(s). Published by Elsevier Inc. on behalf of the International Society of Nephrology.","name":"copyright","label":"Copyright"}],"article-number":"106498"}}