{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T17:37:35Z","timestamp":1786988255281,"version":"build-2736575974"},"reference-count":37,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2015,8,1]],"date-time":"2015-08-01T00:00:00Z","timestamp":1438387200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["emed.theclinics.com","theclinics.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Emergency Medicine Clinics of North America"],"published-print":{"date-parts":[[2015,8]]},"DOI":"10.1016\/j.emc.2015.04.005","type":"journal-article","created":{"date-parts":[[2015,5,30]],"date-time":"2015-05-30T08:48:55Z","timestamp":1432975735000},"page":"539-551","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":32,"title":["Hypertensive Emergencies in the Emergency Department"],"prefix":"10.1016","volume":"33","author":[{"given":"Omoyemi","family":"Adebayo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert L.","family":"Rogers","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.emc.2015.04.005_bib1","doi-asserted-by":"crossref","first-page":"e28","DOI":"10.1161\/01.cir.0000441139.02102.80","article-title":"Heart disease and stroke statistics\u20142014 update: a report from the American Heart Association","volume":"129","author":"Go","year":"2014","journal-title":"Circulation"},{"key":"10.1016\/j.emc.2015.04.005_bib2","doi-asserted-by":"crossref","first-page":"e21","DOI":"10.1161\/CIRCULATIONAHA.108.191261","article-title":"Heart disease and stroke statistics\u20142009 update: a report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee","volume":"119","author":"Lloyd-Jones","year":"2009","journal-title":"Circulation"},{"key":"10.1016\/j.emc.2015.04.005_bib3","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1001\/jama.2013.284427","article-title":"2014 evidence-based guideline for the management of high blood pressure in adults: report from the panel members appointed to the eighth Joint National Committee (JNC 8)","volume":"311","author":"James","year":"2014","journal-title":"JAMA"},{"key":"10.1016\/j.emc.2015.04.005_bib4","doi-asserted-by":"crossref","first-page":"1206","DOI":"10.1161\/01.HYP.0000107251.49515.c2","article-title":"Seventh report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure","volume":"42","author":"Chobanian","year":"2003","journal-title":"Hypertension"},{"key":"10.1016\/j.emc.2015.04.005_bib5","first-page":"43","article-title":"Hypertensive urgency and emergency","volume":"43","author":"Vaidya","year":"2007","journal-title":"Hosp Physician"},{"key":"10.1016\/j.emc.2015.04.005_bib6","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/j.annemergmed.2013.05.012","article-title":"Clinical policy: critical issues in the evaluation and management of adult patients in the emergency department with asymptomatic elevated blood pressure","volume":"62","author":"Wolf","year":"2013","journal-title":"Ann Emerg Med"},{"key":"10.1016\/j.emc.2015.04.005_bib7","first-page":"485","article-title":"Accelerated hypertension\u2014patterns of mortality and clinical factors affecting outcome in treated patients","volume":"86","author":"Webster","year":"1993","journal-title":"Q\u00a0J Med"},{"key":"10.1016\/j.emc.2015.04.005_bib8","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1097\/00126097-200102000-00003","article-title":"Prevalence of blood pressure cuff sizes in a referral practice of 430 consecutive adult hypertensives","volume":"6","author":"Graves","year":"2001","journal-title":"Blood Press Monit"},{"key":"10.1016\/j.emc.2015.04.005_bib9","doi-asserted-by":"crossref","first-page":"1357","DOI":"10.1016\/j.ajem.2011.09.025","article-title":"Optic nerve ultrasound for the detection of elevated intracranial pressure in the hypertensive patient","volume":"30","author":"Roque","year":"2012","journal-title":"Am J Emerg Med"},{"key":"10.1016\/j.emc.2015.04.005_bib10","doi-asserted-by":"crossref","first-page":"1597","DOI":"10.1016\/j.ijcard.2012.04.099","article-title":"Coronary CT angiography outperforms calcium imaging in the triage of acute coronary syndrome","volume":"167","author":"Dedic","year":"2013","journal-title":"Int J Cardiol"},{"key":"10.1016\/j.emc.2015.04.005_bib11","doi-asserted-by":"crossref","first-page":"283","DOI":"10.2174\/157489006778777070","article-title":"Role of perindopril in the prevention of stroke","volume":"1","author":"Papadopoulos","year":"2006","journal-title":"Recent Pat Cardiovasc Drug Discov"},{"key":"10.1016\/j.emc.2015.04.005_bib12","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1001\/archinte.1986.00360130076011","article-title":"Management of hypertension in patients with acute stroke","volume":"146","author":"Lavin","year":"1986","journal-title":"Arch Intern Med"},{"key":"10.1016\/j.emc.2015.04.005_bib13","doi-asserted-by":"crossref","first-page":"1655","DOI":"10.1161\/STROKEAHA.107.181486","volume":"38","author":"Adams","year":"2007","journal-title":"Stroke"},{"key":"10.1016\/j.emc.2015.04.005_bib14","doi-asserted-by":"crossref","first-page":"408","DOI":"10.2165\/00002512-199608060-00002","article-title":"Treatment of post-stroke hypertension: a practical guide","volume":"8","author":"O\u2019Connell","year":"1996","journal-title":"Drugs Aging"},{"key":"10.1016\/j.emc.2015.04.005_bib15","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1016\/S0140-6736(00)02539-3","article-title":"Hypertensive emergencies","volume":"356","author":"Vaughan","year":"2000","journal-title":"Lancet"},{"key":"10.1016\/j.emc.2015.04.005_bib16","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1111\/j.1365-2362.2010.02450.x","article-title":"Randomized placebo controlled trial of furosemide on subjective perception of dyspnea in patients with pulmonary edema because of hypertensive crisis","volume":"41","author":"Holzer-Richling","year":"2011","journal-title":"Eur J Clin Invest"},{"key":"10.1016\/j.emc.2015.04.005_bib17","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/j.ccl.2005.09.002","article-title":"Hypertensive crisis: hypertensive emergencies and urgencies","volume":"24","author":"Aggarwal","year":"2006","journal-title":"Cardiol Clin"},{"key":"10.1016\/j.emc.2015.04.005_bib18","doi-asserted-by":"crossref","first-page":"1110","DOI":"10.1213\/ane.0b013e31818240db","article-title":"The ECLIPSE trials: comparative studies of clevidipine to nitroglycerin, sodium nitroprusside, and nicardipine for acute hypertension treatment in cardiac surgery patients","volume":"107","author":"Aronson","year":"2008","journal-title":"Anesth Analg"},{"key":"10.1016\/j.emc.2015.04.005_bib19","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1016\/j.annemergmed.2008.04.025","article-title":"Clevidipine, an intravenous dihydropyridine calcium channel blocker, is safe and effective for the treatment of patients with acute severe hypertension","volume":"53","author":"Pollack","year":"2009","journal-title":"Ann Emerg Med"},{"key":"10.1016\/j.emc.2015.04.005_bib20","unstructured":"Cleviprex (clevidipine butyrate) [package insert]. Clayton, NC: Hospira; 2008."},{"key":"10.1016\/j.emc.2015.04.005_bib21","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1097\/MCC.0b013e32834cd31d","article-title":"Hypertensive emergencies: an update","volume":"17","author":"Marik","year":"2011","journal-title":"Curr Opin Crit Care"},{"issue":"8607","key":"10.1016\/j.emc.2015.04.005_bib22","first-page":"349","article-title":"Randomized trial of intravenous streptokinase, oral aspirin, both, or neither among 17187 cases of suspected acute myocardial infarction","volume":"2","year":"1988","journal-title":"Lancet"},{"key":"10.1016\/j.emc.2015.04.005_bib23","doi-asserted-by":"crossref","first-page":"e78","DOI":"10.1016\/j.jacc.2012.11.019","article-title":"2013 ACCF\/AHA guideline for the management of ST-elevation myocardial infarction: a report of the American College of Cardiology Foundation\/American Heart Association Task Force on Practice Guidelines","volume":"61","author":"O'Gara","year":"2013","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.emc.2015.04.005_bib24","doi-asserted-by":"crossref","first-page":"732","DOI":"10.1161\/01.CIR.57.4.732","article-title":"Effect of nitroprusside on regional myocardial blood flow in coronary artery disease: results in 25 patients and comparison with nitroglycerin","volume":"57","author":"Mann","year":"1978","journal-title":"Circulation"},{"key":"10.1016\/j.emc.2015.04.005_bib25","doi-asserted-by":"crossref","first-page":"1129","DOI":"10.1056\/NEJM198205133061902","article-title":"Effect of short-term infusion of sodium nitroprusside on mortality rate in acute myocardial infarction complicated by left ventricular failure: results of a Veterans Administration cooperative study","volume":"306","author":"Cohn","year":"1982","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.emc.2015.04.005_bib26","doi-asserted-by":"crossref","first-page":"897","DOI":"10.1001\/jama.283.7.897","article-title":"International Registry of Acute Aortic Dissection (IRAD): new insights from an old disease","volume":"283","author":"Hagan","year":"2000","journal-title":"JAMA"},{"key":"10.1016\/j.emc.2015.04.005_bib27","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1161\/CIRCULATIONAHA.110.958975","article-title":"Acute aortic dissection: clinician update","volume":"122","author":"Braverman","year":"2010","journal-title":"Circulation"},{"key":"10.1016\/j.emc.2015.04.005_bib28","doi-asserted-by":"crossref","first-page":"970","DOI":"10.1161\/01.CIR.81.3.970","article-title":"Renal and hemodynamic effects of intravenous fenoldopam versus nitroprusside in severe hypertension","volume":"81","author":"Elliott","year":"1990","journal-title":"Circulation"},{"key":"10.1016\/j.emc.2015.04.005_bib29","doi-asserted-by":"crossref","first-page":"I59","DOI":"10.1161\/01.HYP.15.2_Suppl.I59","article-title":"Intravenous fenoldopam versus sodium nitroprusside in patients with severe hypertension","volume":"15","author":"Reisin","year":"1990","journal-title":"Hypertension"},{"key":"10.1016\/j.emc.2015.04.005_bib30","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1007\/s12016-009-8191-5","article-title":"Scleroderma renal crisis: a rare but severe complication of systemic sclerosis","volume":"40","author":"Mouthon","year":"2011","journal-title":"Clin Rev Allergy Immunol"},{"key":"10.1016\/j.emc.2015.04.005_bib31","doi-asserted-by":"crossref","first-page":"897","DOI":"10.7326\/0003-4819-112-12-897","article-title":"Potentiation of cocaine-induced coronary vasoconstriction by beta-adrenergic blockade","volume":"112","author":"Lange","year":"1990","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.emc.2015.04.005_bib32","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/S0033-0620(97)80023-0","article-title":"Cocaine-induced myocardial ischemia and infarction: pathophysiology, recognition, and management","volume":"40","author":"Pitts","year":"1997","journal-title":"Prog Cardiovasc Dis"},{"key":"10.1016\/j.emc.2015.04.005_bib33","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1681\/ASN.V91133","article-title":"Malignant hypertension and hypertensive emergencies","volume":"9","author":"Kitiyakara","year":"1998","journal-title":"J\u00a0Am Soc Nephrol"},{"key":"10.1016\/j.emc.2015.04.005_bib34","doi-asserted-by":"crossref","first-page":"1343","DOI":"10.2146\/ajhp080348.p1","article-title":"Intravenous therapy for hypertensive emergencies, part 1","volume":"66","author":"Rhoney","year":"2009","journal-title":"Am J Health Syst Pharm"},{"key":"10.1016\/j.emc.2015.04.005_bib35","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1016\/j.ajem.2012.09.027","article-title":"Safety of \u03b2-blockers in the acute management of cocaine-associated chest pain","volume":"31","author":"Ibrahim","year":"2013","journal-title":"Am J Emerg Med"},{"key":"10.1016\/j.emc.2015.04.005_bib36","doi-asserted-by":"crossref","first-page":"955","DOI":"10.1136\/bmj.327.7421.955","article-title":"Hydralazine for treatment of severe hypertension in pregnancy: meta-analysis","volume":"327","author":"Magee","year":"2003","journal-title":"BMJ"},{"issue":"1","key":"10.1016\/j.emc.2015.04.005_bib37","doi-asserted-by":"crossref","DOI":"10.1002\/14651858.CD004661.pub3","article-title":"Magnesium sulfate for women at risk of preterm birth for neuroprotection of the fetus","author":"Doyle","year":"2009","journal-title":"Cochrane Database Syst Rev"}],"container-title":["Emergency Medicine Clinics of North America"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0733862715000292?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0733862715000292?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,5,10]],"date-time":"2022-05-10T01:04:49Z","timestamp":1652144689000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0733862715000292"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,8]]},"references-count":37,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2015,8]]}},"alternative-id":["S0733862715000292"],"URL":"https:\/\/doi.org\/10.1016\/j.emc.2015.04.005","relation":{},"ISSN":["0733-8627"],"issn-type":[{"value":"0733-8627","type":"print"}],"subject":[],"published":{"date-parts":[[2015,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Hypertensive Emergencies in the Emergency Department","name":"articletitle","label":"Article Title"},{"value":"Emergency Medicine Clinics of North America","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.emc.2015.04.005","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}