{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,2]],"date-time":"2025-07-02T04:25:22Z","timestamp":1751430322857,"version":"3.41.0"},"reference-count":73,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","theclinics.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Emergency Medicine Clinics of North America"],"published-print":{"date-parts":[[2025,8]]},"DOI":"10.1016\/j.emc.2025.03.007","type":"journal-article","created":{"date-parts":[[2025,5,6]],"date-time":"2025-05-06T19:32:16Z","timestamp":1746559936000},"page":"391-406","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Sickle Cell Disease"],"prefix":"10.1016","volume":"43","author":[{"given":"Lauren V.","family":"Ready","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mary Carroll","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"suffix":"Jr.","given":"John C.","family":"Perkins","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"year":"2024","series-title":"Data and statistics on sickle cell disease","key":"10.1016\/j.emc.2025.03.007_bib1"},{"issue":"13","key":"10.1016\/j.emc.2025.03.007_bib2","doi-asserted-by":"crossref","first-page":"3276","DOI":"10.1182\/bloodadvances.2022009202","article-title":"Long-term survival with sickle cell disease: a nationwide cohort study of Medicare and Medicaid beneficiaries","volume":"7","author":"Jiao","year":"2023","journal-title":"Blood Adv"},{"issue":"8","key":"10.1016\/j.emc.2025.03.007_bib3","first-page":"1","article-title":"Evidence-based management of sickle cell disease in the emergency department","volume":"13","author":"Glassberg","year":"2011","journal-title":"Emerg Med Pract"},{"issue":"2","key":"10.1016\/j.emc.2025.03.007_bib4","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1016\/j.jped.2019.05.004","article-title":"Analgesic management of uncomplicated acute sickle-cell pain crisis in pediatrics: a systematic review and meta-analysis","volume":"96","author":"Saramba","year":"2020","journal-title":"J Pediatr"},{"issue":"18","key":"10.1016\/j.emc.2025.03.007_bib5","doi-asserted-by":"crossref","first-page":"3647","DOI":"10.1182\/blood-2012-04-383430","article-title":"Sickle cell pain: a critical reappraisal","volume":"120","author":"Ballas","year":"2012","journal-title":"Blood"},{"issue":"5\u20136","key":"10.1016\/j.emc.2025.03.007_bib6","doi-asserted-by":"crossref","first-page":"485","DOI":"10.3109\/03630269.2011.610914","article-title":"Opioid management and dependency among adult patients with sickle cell disease","volume":"35","author":"Feliu","year":"2011","journal-title":"Hemoglobin"},{"issue":"3","key":"10.1016\/j.emc.2025.03.007_bib7","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1097\/MOH.0b013e328329e167","article-title":"Acute pain in children and adults with sickle cell disease: management in the absence of evidence-based guidelines","volume":"16","author":"Field","year":"2009","journal-title":"Curr Opin Hematol"},{"issue":"11","key":"10.1016\/j.emc.2025.03.007_bib8","first-page":"2","article-title":"Adult sickle cell emergencies","volume":"20","author":"Lopez","year":"2006","journal-title":"Crit Decis Emerg Med"},{"issue":"13","key":"10.1016\/j.emc.2025.03.007_bib9","doi-asserted-by":"crossref","first-page":"1021","DOI":"10.1056\/NEJM199904013401307","article-title":"Management of sickle cell disease","volume":"340","author":"Steinberg","year":"1999","journal-title":"N Engl J Med"},{"issue":"9 Suppl","key":"10.1016\/j.emc.2025.03.007_bib10","first-page":"S5","article-title":"Chronic pain perspectives: sickle cell disease: gaining control over the pain","volume":"61","author":"Gregory","year":"2012","journal-title":"J Fam Pract"},{"issue":"6","key":"10.1016\/j.emc.2025.03.007_bib11","doi-asserted-by":"crossref","first-page":"840","DOI":"10.1016\/j.annemergmed.2009.03.026","article-title":"Even \u201cfrequent flyers\u201d die","volume":"54","author":"Abbott","year":"2009","journal-title":"Ann Emerg Med"},{"key":"10.1016\/j.emc.2025.03.007_bib12","series-title":"GeneReviews\u00ae","first-page":"2","article-title":"Sickle cell disease","author":"Bender","year":"2003"},{"issue":"2","key":"10.1016\/j.emc.2025.03.007_bib13","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1016\/j.annemergmed.2007.09.033","article-title":"Meperidine for acute sickle cell pain in the emergency department: revisited controversy","volume":"51","author":"Ballas","year":"2008","journal-title":"Ann Emerg Med"},{"issue":"6","key":"10.1016\/j.emc.2025.03.007_bib14","doi-asserted-by":"crossref","first-page":"766","DOI":"10.1016\/j.annemergmed.2008.05.043","article-title":"Meperidine for acute sickle cell crisis: what is the rationale?","volume":"52","author":"Phillips","year":"2008","journal-title":"Ann Emerg Med"},{"issue":"2","key":"10.1016\/j.emc.2025.03.007_bib15","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1016\/j.annemergmed.2007.09.026","article-title":"Use of meperidine as the analgesic of choice in treating pain from acute painful sickle cell crisis","volume":"51","author":"Morgan","year":"2008","journal-title":"Ann Emerg Med"},{"issue":"3","key":"10.1016\/j.emc.2025.03.007_bib16","doi-asserted-by":"crossref","first-page":"997","DOI":"10.1182\/blood-2007-07-089144","article-title":"Treatment and prevention of pain due to vaso-occlusive crises in adults with sickle cell disease: an educational void","volume":"111","author":"Solomon","year":"2008","journal-title":"Blood"},{"issue":"12","key":"10.1016\/j.emc.2025.03.007_bib17","doi-asserted-by":"crossref","first-page":"2196","DOI":"10.3390\/medicina59122196","article-title":"Pain control for sickle cell crisis, a novel approach? A retrospective study","volume":"59","author":"Roll\u00e9","year":"2023","journal-title":"Medicina"},{"year":"2002","series-title":"National Heart, Lung, and Blood Institute. The man- agement of sickle cell disease","key":"10.1016\/j.emc.2025.03.007_bib18"},{"issue":"4","key":"10.1016\/j.emc.2025.03.007_bib19","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1016\/j.annemergmed.2013.02.004","article-title":"Emergency provider analgesic practices and attitudes toward patients with sickle cell disease","volume":"62","author":"Glassberg","year":"2013","journal-title":"Ann Emerg Med"},{"issue":"1","key":"10.1016\/j.emc.2025.03.007_bib20","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/S0733-8627(03)00057-9","article-title":"Hematologic emergencies in the pediatric emergency room","volume":"20","author":"Sadowitz","year":"2002","journal-title":"Emerg Med Clin North Am"},{"issue":"6","key":"10.1016\/j.emc.2025.03.007_bib21","doi-asserted-by":"crossref","first-page":"e1552","DOI":"10.1542\/peds.2010-3686","article-title":"Management of children with sickle cell disease: a comprehensive review of the literature","volume":"128","author":"Kavanagh","year":"2011","journal-title":"Pediatrics"},{"issue":"8996","key":"10.1016\/j.emc.2025.03.007_bib22","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1016\/S0140-6736(96)90437-7","article-title":"Sickle cell pain crisis","volume":"347","author":"Ward","year":"1996","journal-title":"Lancet"},{"issue":"5","key":"10.1016\/j.emc.2025.03.007_bib23","doi-asserted-by":"crossref","first-page":"785","DOI":"10.1016\/j.hoc.2005.07.008","article-title":"Pain management of sickle cell disease","volume":"19","author":"Ballas","year":"2005","journal-title":"Hematol Oncol Clin North Am"},{"issue":"3","key":"10.1016\/j.emc.2025.03.007_bib24","doi-asserted-by":"crossref","first-page":"699","DOI":"10.1016\/S0031-3955(05)70233-9","article-title":"The management of pain in sickle cell disease","volume":"47","author":"Yaster","year":"2000","journal-title":"Pediatr Clin North Am"},{"issue":"3","key":"10.1016\/j.emc.2025.03.007_bib25","doi-asserted-by":"crossref","first-page":"320","DOI":"10.4065\/83.3.320","article-title":"The sickle cell crisis: a dilemma in pain relief","volume":"83","author":"Geller","year":"2008","journal-title":"Mayo Clin Proc"},{"key":"10.1016\/j.emc.2025.03.007_bib26","unstructured":"Borhade MB, Kondamudi NP. Sickle cell crisis. 2018."},{"issue":"6","key":"10.1016\/j.emc.2025.03.007_bib27","doi-asserted-by":"crossref","first-page":"e1634","DOI":"10.1542\/peds.2013-2065","article-title":"Intravenous magnesium sulfate for vaso-occlusive episodes in sickle cell disease","volume":"132","author":"Goldman","year":"2013","journal-title":"Pediatrics"},{"issue":"14","key":"10.1016\/j.emc.2025.03.007_bib28","doi-asserted-by":"crossref","first-page":"1651","DOI":"10.1182\/blood-2015-05-647107","article-title":"A multicenter randomized controlled trial of intravenous magnesium for sickle cell pain crisis in children","volume":"126","author":"Brousseau","year":"2015","journal-title":"Blood"},{"issue":"6","key":"10.1016\/j.emc.2025.03.007_bib29","doi-asserted-by":"crossref","DOI":"10.1002\/pbc.29695","article-title":"Regional anesthesia for sickle cell disease vaso-occlusive crisis: a single-center case series","volume":"69","author":"Karsenty","year":"2022","journal-title":"Pediatr Blood Cancer"},{"issue":"1","key":"10.1016\/j.emc.2025.03.007_bib30","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1001\/archinte.1979.03630380047016","article-title":"\u201cAcute chest syndrome\u201d in adults with sickle cell anemia. Microbiology, treatment, and prevention","volume":"139","author":"Charache","year":"1979","journal-title":"Arch Intern Med"},{"issue":"2","key":"10.1016\/j.emc.2025.03.007_bib31","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1097\/00062752-200103000-00009","article-title":"Acute chest syndrome of sickle cell disease: new light on an old problem","volume":"8","author":"Stuart","year":"2001","journal-title":"Curr Opin Hematol"},{"issue":"4","key":"10.1016\/j.emc.2025.03.007_bib32","doi-asserted-by":"crossref","first-page":"1082","DOI":"10.1016\/j.chest.2015.12.016","article-title":"Crises in sickle cell disease","volume":"149","author":"Novelli","year":"2016","journal-title":"Chest"},{"issue":"5","key":"10.1016\/j.emc.2025.03.007_bib33","doi-asserted-by":"crossref","first-page":"1555","DOI":"10.1182\/blood.V94.5.1555","article-title":"Sickle cell acute chest syndrome: pathogenesis and rationale for treatment","volume":"94","author":"Stuart","year":"1999","journal-title":"Blood"},{"issue":"5","key":"10.1016\/j.emc.2025.03.007_bib34","doi-asserted-by":"crossref","first-page":"1787","DOI":"10.1182\/blood.V89.5.1787","article-title":"Acute chest syndrome in sickle cell disease: clinical presentation and course","volume":"89","author":"Vichinsky","year":"1997","journal-title":"Blood"},{"issue":"9","key":"10.1016\/j.emc.2025.03.007_bib35","doi-asserted-by":"crossref","first-page":"1022","DOI":"10.1164\/rccm.201105-0783OC","article-title":"Pulmonary artery thrombosis during acute chest syndrome in sickle cell disease","volume":"184","author":"Mekontso","year":"2011","journal-title":"Am J Respir Crit Care Med"},{"issue":"3","key":"10.1016\/j.emc.2025.03.007_bib36","doi-asserted-by":"crossref","first-page":"352","DOI":"10.1007\/s11239-013-0895-y","article-title":"Sickle cell disease and venous thromboembolism: what the anticoagulation expert needs to know","volume":"35","author":"Naik","year":"2013","journal-title":"J Thromb Thrombolysis"},{"issue":"5","key":"10.1016\/j.emc.2025.03.007_bib37","doi-asserted-by":"crossref","first-page":"760","DOI":"10.1111\/j.1538-7836.2012.04697.x","article-title":"Pulmonary embolism in sickle cell disease: a case-control study","volume":"10","author":"Novelli","year":"2012","journal-title":"J Thromb Haemost"},{"issue":"18 Suppl","key":"10.1016\/j.emc.2025.03.007_bib38","first-page":"S335","article-title":"Sickle cell disease: current treatment and emerging therapies","volume":"25","author":"Neumayr","year":"2019","journal-title":"Am J Manag Care"},{"issue":"1","key":"10.1016\/j.emc.2025.03.007_bib39","article-title":"Blood transfusions for treating acute chest syndrome in people with sickle cell disease","volume":"1","author":"Dolatkhah","year":"2020","journal-title":"Cochrane Database Syst Rev"},{"issue":"12","key":"10.1016\/j.emc.2025.03.007_bib40","article-title":"Inhaled bronchodilators for acute chest syndrome in people with sickle cell disease","volume":"12","author":"Knight-Madden","year":"2022","journal-title":"Cochrane Database Syst Rev"},{"issue":"25","key":"10.1016\/j.emc.2025.03.007_bib41","doi-asserted-by":"crossref","first-page":"1855","DOI":"10.1056\/NEJM200006223422502","article-title":"Causes and outcomes of the acute chest syndrome in sickle cell disease. National Acute Chest Syndrome Study Group","volume":"342","author":"Vichinsky","year":"2000","journal-title":"N Engl J Med"},{"issue":"5","key":"10.1016\/j.emc.2025.03.007_bib42","doi-asserted-by":"crossref","first-page":"472","DOI":"10.1097\/MOH.0b013e328363442f","article-title":"Hemostatic abnormalities in sickle cell disease","volume":"20","author":"Lim","year":"2013","journal-title":"Curr Opin Hematol"},{"author":"Weinberg","key":"10.1016\/j.emc.2025.03.007_bib43"},{"issue":"9757","key":"10.1016\/j.emc.2025.03.007_bib44","doi-asserted-by":"crossref","first-page":"2018","DOI":"10.1016\/S0140-6736(10)61029-X","article-title":"Sickle-cell disease","volume":"376","author":"Rees","year":"2010","journal-title":"Lancet"},{"key":"10.1016\/j.emc.2025.03.007_bib45","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1146\/annurev-med-120611-143127","article-title":"Sickle cell disease, vasculopathy, and therapeutics","volume":"64","author":"Kassim","year":"2013","journal-title":"Annu Rev Med"},{"author":"George","key":"10.1016\/j.emc.2025.03.007_bib46"},{"issue":"4","key":"10.1016\/j.emc.2025.03.007_bib47","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1007\/s00408-008-9092-8","article-title":"Pulmonary hypertension associated with sickle cell disease: pathophysiology and rationale for treatment","volume":"186","author":"Benza","year":"2008","journal-title":"Lung"},{"issue":"9442","key":"10.1016\/j.emc.2025.03.007_bib48","doi-asserted-by":"crossref","first-page":"1343","DOI":"10.1016\/S0140-6736(04)17192-4","article-title":"Sickle-cell disease","volume":"364","author":"Stuart","year":"2004","journal-title":"Lancet"},{"issue":"1","key":"10.1016\/j.emc.2025.03.007_bib49","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1016\/j.ijid.2009.03.010","article-title":"Infection in sickle cell disease: a review","volume":"14","author":"Booth","year":"2010","journal-title":"Int J Infect Dis"},{"issue":"12","key":"10.1016\/j.emc.2025.03.007_bib50","doi-asserted-by":"crossref","first-page":"6137","DOI":"10.3390\/ijerph20126137","article-title":"Analysis of the 2007-2018 national health interview survey (NHIS): examining neurological complications among children with sickle cell disease in the United States","volume":"20","author":"Peprah","year":"2023","journal-title":"Int J Environ Res Public Health"},{"issue":"4","key":"10.1016\/j.emc.2025.03.007_bib51","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1002\/ajh.25401","article-title":"Bone marrow transplantation for adolescents and young adults with sickle cell disease: results of a prospective multicenter pilot study","volume":"94","author":"Krishnamurti","year":"2019","journal-title":"Am J Hematol"},{"issue":"6","key":"10.1016\/j.emc.2025.03.007_bib52","doi-asserted-by":"crossref","first-page":"E110","DOI":"10.1002\/ajh.24718","article-title":"Beyond the transition of adolescents and young adults with sickle cell disease to adult care: role of geography","volume":"92","author":"Anderson","year":"2017","journal-title":"Am J Hematol"},{"issue":"6","key":"10.1016\/j.emc.2025.03.007_bib53","doi-asserted-by":"crossref","first-page":"1058","DOI":"10.1111\/bjh.15250","article-title":"Novel findings from the multinational DOVE study on geographic and age-related differences in pain perception and analgesic usage in children with sickle cell anaemia","volume":"184","author":"Kanter","year":"2019","journal-title":"Br J Haematol"},{"issue":"1","key":"10.1016\/j.emc.2025.03.007_bib54","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/j.jpain.2023.07.029","article-title":"Biopsychosocial factors associated with pain and pain- related outcomes in adults and children with sickle cell disease: a multivariable analysis of the GRNDaD multicenter registry","volume":"25","author":"Kenney","year":"2024","journal-title":"J Pain"},{"key":"10.1016\/j.emc.2025.03.007_bib55","first-page":"2402","article-title":"Sickle cell disease","volume":"2016","author":"Meremikwu","year":"2016","journal-title":"BMJ Clin Evid"},{"key":"10.1016\/j.emc.2025.03.007_bib56","doi-asserted-by":"crossref","first-page":"335","DOI":"10.2147\/JMDH.S90630","article-title":"Sickle cell retinopathy: improving care with a multidisciplinary approach","volume":"10","author":"Menaa","year":"2017","journal-title":"J Multidiscip Healthc"},{"issue":"5","key":"10.1016\/j.emc.2025.03.007_bib57","doi-asserted-by":"crossref","first-page":"934","DOI":"10.1016\/j.jpainsymman.2014.02.002","article-title":"Perceived discrimination in health care is associated with a greater burden of pain in sickle cell disease","volume":"48","author":"Haywood","year":"2014","journal-title":"J Pain Symptom Manage"},{"issue":"1","key":"10.1016\/j.emc.2025.03.007_bib58","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1002\/ajh.2830460108","article-title":"Enhancement of pain control with ketorolac tromethamine in patients with sickle cell vaso-occlusive crisis","volume":"46","author":"Perlin","year":"1994","journal-title":"Am J Hematol"},{"issue":"5","key":"10.1016\/j.emc.2025.03.007_bib59","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1007\/s11606-017-4289-2","article-title":"Do words matter? Stigmatizing language and the transmission of bias in the medical record","volume":"33","author":"Goddu","year":"2018","journal-title":"J Gen Intern Med"},{"issue":"3","key":"10.1016\/j.emc.2025.03.007_bib60","doi-asserted-by":"crossref","DOI":"10.1001\/jamanetworkopen.2023.4584","article-title":"Changes in hydroxyurea use among youths enrolled in medicaid with sickle cell anemia after 2014 revision of clinical guidelines","volume":"6","author":"Reeves","year":"2023","journal-title":"JAMA Netw Open"},{"issue":"1","key":"10.1016\/j.emc.2025.03.007_bib61","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1186\/s12887-021-03015-1","article-title":"Clinical depression in children and adolescents with sickle cell anaemia: influencing factors in a resource-limited setting","volume":"21","author":"Ezenwosu","year":"2021","journal-title":"BMC Pediatr"},{"issue":"5","key":"10.1016\/j.emc.2025.03.007_bib62","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1111\/bjh.14575","article-title":"How we manage iron overload in sickle cell patients","volume":"177","author":"Coates","year":"2017","journal-title":"Br J Haematol"},{"issue":"5","key":"10.1016\/j.emc.2025.03.007_bib63","doi-asserted-by":"crossref","first-page":"1143","DOI":"10.1182\/bloodadvances.2023012002","article-title":"Burden of employment loss and absenteeism in adults and caregivers of children with sickle cell disease","volume":"8","author":"Gordon","year":"2024","journal-title":"Blood Adv"},{"issue":"6","key":"10.1016\/j.emc.2025.03.007_bib64","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1111\/acem.14149","article-title":"Does intravenous acetaminophen reduce opioid requirement in pediatric emergency department patients with acute sickle cell crises?","volume":"28","author":"Dhebaria","year":"2021","journal-title":"Acad Emerg Med"},{"issue":"1","key":"10.1016\/j.emc.2025.03.007_bib65","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1186\/s13045-022-01237-z","article-title":"Advances in the diagnosis and treatment of sickle cell disease","volume":"15","author":"Brandow","year":"2022","journal-title":"J Hematol Oncol"},{"issue":"1","key":"10.1016\/j.emc.2025.03.007_bib66","doi-asserted-by":"crossref","DOI":"10.1155\/2015\/540154","article-title":"Morphine for the treatment of pain in sickle cell disease","volume":"2015","author":"Gupta","year":"2015","journal-title":"Sci World J"},{"key":"10.1016\/j.emc.2025.03.007_bib67","article-title":"Leg ulcers in sickle cell disease patients","volume":"19","author":"Granja","year":"2020","journal-title":"Jornal Vascular Brasileiro"},{"issue":"9","key":"10.1016\/j.emc.2025.03.007_bib68","doi-asserted-by":"crossref","first-page":"898","DOI":"10.1046\/j.1464-410X.2002.03022.x","article-title":"Priapism in sickle-cell disease; incidence, risk factors and complications\u2013an international multicentre study","volume":"90","author":"Adeyoju","year":"2002","journal-title":"BJU Int"},{"issue":"2","key":"10.1016\/j.emc.2025.03.007_bib69","first-page":"e54463","article-title":"Intravenous hydration and associated outcomes in patients with sickle cell disease admitted with vaso-occlusive crises: a systematic review","volume":"16","author":"Pandey","year":"2024","journal-title":"Cureus"},{"issue":"6","key":"10.1016\/j.emc.2025.03.007_bib70","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1002\/ajh.25471","article-title":"Normal saline bolus use in pediatric emergency departments is associated with poorer pain control in children with sickle cell anemia and vaso- occlusive pain","volume":"94","author":"Carden","year":"2019","journal-title":"Am J Hematol"},{"issue":"3","key":"10.1016\/j.emc.2025.03.007_bib71","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1016\/j.emc.2014.04.011","article-title":"Sickle cell disease in the emergency department","volume":"32","author":"Lovett","year":"2014","journal-title":"Emerg Med Clin"},{"issue":"6","key":"10.1016\/j.emc.2025.03.007_bib72","doi-asserted-by":"crossref","first-page":"852","DOI":"10.1111\/bjh.12323","article-title":"The effect of hydroxycarbamide therapy on survival of children with sickle cell disease","volume":"161","author":"de Castro Lobo","year":"2013","journal-title":"Br J Haematol"},{"issue":"2","key":"10.1016\/j.emc.2025.03.007_bib73","first-page":"157","article-title":"Association of care in a medical home and health care utilization among children with sickle cell disease","volume":"105","author":"Raphael","year":"2013","journal-title":"J Natl Med Assoc"}],"container-title":["Emergency Medicine Clinics of North America"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0733862725000185?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0733862725000185?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T22:47:26Z","timestamp":1751410046000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0733862725000185"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8]]},"references-count":73,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2025,8]]}},"alternative-id":["S0733862725000185"],"URL":"https:\/\/doi.org\/10.1016\/j.emc.2025.03.007","relation":{},"ISSN":["0733-8627"],"issn-type":[{"type":"print","value":"0733-8627"}],"subject":[],"published":{"date-parts":[[2025,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Sickle Cell Disease","name":"articletitle","label":"Article Title"},{"value":"Emergency Medicine Clinics of North America","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.emc.2025.03.007","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}