{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T10:56:03Z","timestamp":1790333763612,"version":"4.1.0"},"reference-count":31,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2008,10,1]],"date-time":"2008-10-01T00:00:00Z","timestamp":1222819200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["L'Enc\u00e9phale"],"published-print":{"date-parts":[[2008,10]]},"DOI":"10.1016\/j.encep.2007.10.011","type":"journal-article","created":{"date-parts":[[2008,3,13]],"date-time":"2008-03-13T09:50:12Z","timestamp":1205401812000},"page":"496-503","source":"Crossref","is-referenced-by-count":10,"title":["Approches substitutive et di\u00e9t\u00e9tique du trouble autistique de l\u2019enfant\u00a0: int\u00e9r\u00eats ou limites\u00a0?"],"prefix":"10.1016","volume":"34","author":[{"given":"H.","family":"Hjiej","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Doyen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Couprie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K.","family":"Kaye","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Y.","family":"Contejean","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"4","key":"10.1016\/j.encep.2007.10.011_bib1","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1023\/A:1025071014191","article-title":"Plasma amino acids profiles in children with autism: potential risk of nutritional deficiencies","volume":"33","author":"Arnold","year":"2003","journal-title":"J Autism Dev Disord"},{"issue":"4","key":"10.1016\/j.encep.2007.10.011_bib2","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1542\/peds.107.4.e46","article-title":"Severe nutritional deficiencies in toddlers resulting from health food mild alternatives","volume":"107","author":"Carvalho","year":"2001","journal-title":"Pediatrics"},{"issue":"9","key":"10.1016\/j.encep.2007.10.011_bib3","doi-asserted-by":"crossref","first-page":"1076","DOI":"10.1111\/j.1651-2227.1996.tb14220.x","article-title":"Abnormal intestinal permeability in children with autism","volume":"85","author":"D\u2019Eufemia","year":"1996","journal-title":"Acta Paediatr"},{"issue":"3","key":"10.1016\/j.encep.2007.10.011_bib4","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1007\/s10803-006-0079-0","article-title":"The gluten-free, casein-free diet in autism: results of a preliminary ouble blind clinical trial","volume":"36","author":"Elder","year":"1996","journal-title":"J Autism Dev Disord"},{"issue":"5","key":"10.1016\/j.encep.2007.10.011_bib5","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1007\/s10803-004-2549-6","article-title":"Secretin as a treatment for autism: a review of the evidence","volume":"34","author":"Esch","year":"2004","journal-title":"J Autism Dev Disord"},{"issue":"2","key":"10.1016\/j.encep.2007.10.011_bib6","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1177\/08830738030180020501","article-title":"Application of a ketogenic diet in children with autistic behavior: pilot study","volume":"18","author":"Evangeliou","year":"2003","journal-title":"J Child Neurol"},{"key":"10.1016\/j.encep.2007.10.011_bib7","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1111\/j.1469-8749.1997.tb07437.x","article-title":"Possible effects of tetrahydrobiopterin treatment in six children with autism clinical and positron emission tomography data: a pilot study","volume":"39","author":"Fernell","year":"1997","journal-title":"Dev Med Child Neurol"},{"issue":"4","key":"10.1016\/j.encep.2007.10.011_bib8","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1023\/A:1025861522935","article-title":"High-dose pyridoxine and magnesium administration in children with autistic disorder: an absence of salutary effects in a double-blind, placebo-controlled study","volume":"27","author":"Findling","year":"1997","journal-title":"J Autism Dev Disord"},{"key":"10.1016\/j.encep.2007.10.011_bib9","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1007\/BF01537869","article-title":"Plasma zinc, cooper and amino acid levels in the blood of autistic children","volume":"8","author":"Jackson","year":"1978","journal-title":"J Autism Dev Disord"},{"key":"10.1016\/j.encep.2007.10.011_bib10","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1177\/088307380101600303","article-title":"Effectiveness of N,N-dimethylglycine in autism and pervasive developmental disorder","volume":"16","author":"Kern","year":"2001","journal-title":"J Child Neurol"},{"issue":"5","key":"10.1016\/j.encep.2007.10.011_bib11","first-page":"22","article-title":"An approach to the nutritional management of autism","volume":"9","author":"Kidd","year":"2003","journal-title":"Alternative therapies"},{"key":"10.1016\/j.encep.2007.10.011_bib12","first-page":"315","article-title":"Dietary intervention in autistic syndromes","volume":"3","author":"Knivsberg","year":"1990","journal-title":"Brain dysfunct"},{"key":"10.1016\/j.encep.2007.10.011_bib13","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1007\/BF01531292","article-title":"Histidinemia and infantile autism","volume":"9","author":"Kotsopoulos","year":"1979","journal-title":"J Autism Dev Disord"},{"key":"10.1016\/j.encep.2007.10.011_bib14","unstructured":"Laidler JR. Mercury detoxification consensus group position paper. San Diego Autism Research Institute 2001."},{"issue":"2","key":"10.1016\/j.encep.2007.10.011_bib15","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1007\/BF01531686","article-title":"Effects of pyridoxine and magnesium on autistic symptoms-initial observations","volume":"11","author":"Lelord","year":"1981","journal-title":"J Autism Dev Disord"},{"issue":"3","key":"10.1016\/j.encep.2007.10.011_bib16","first-page":"137","article-title":"Food allergy and infantile autism","volume":"37","author":"Lucarelli","year":"1995","journal-title":"Panminerva Med"},{"issue":"5","key":"10.1016\/j.encep.2007.10.011_bib17","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1023\/A:1005563926383","article-title":"Metabolic approaches to the treatment of autism spectrum disorders","volume":"30","author":"Page","year":"2000","journal-title":"J Autism Dev Disord"},{"issue":"2","key":"10.1016\/j.encep.2007.10.011_bib18","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/0091-3057(79)90002-9","article-title":"Morphine reduces social cohesion in rats","volume":"11","author":"Panskepp","year":"1979","journal-title":"Pharmacol Biochem Behav"},{"key":"10.1016\/j.encep.2007.10.011_bib19","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1016\/S0006-3223(97)00267-9","article-title":"Autism and coeliac disease: failure to validate the hypothesis that a link might exist","volume":"42","author":"Pavone","year":"1997","journal-title":"Biol Psychiatry"},{"key":"10.1016\/j.encep.2007.10.011_bib20","first-page":"575","article-title":"Amino compounds and organic acids in CF, plasma and urine of autistic children","volume":"13","author":"Perry","year":"1978","journal-title":"Biol Psychiatry"},{"issue":"5","key":"10.1016\/j.encep.2007.10.011_bib21","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1007\/BF02178295","article-title":"Efficacy of vitamin B6 and magnesium in the treatment of autism: a methodology review and summary of outcomes","volume":"25","author":"Pfeiffer","year":"1995","journal-title":"J Autism Dev Disord"},{"key":"10.1016\/j.encep.2007.10.011_bib22","first-page":"1","article-title":"Gluten, milk proteins and autism: dietary intervention effects on behaviorand peptide secretion","volume":"42","author":"Reichelt","year":"1990","journal-title":"J Appl Nutr"},{"issue":"4","key":"10.1016\/j.encep.2007.10.011_bib23","doi-asserted-by":"crossref","first-page":"472","DOI":"10.1176\/ajp.135.4.472","article-title":"The effect of high doses of vitamin B6 on autistic children: a double-blind crossover study","volume":"135","author":"Rimland","year":"1978","journal-title":"Am J Psychiatry"},{"key":"10.1016\/j.encep.2007.10.011_bib24","doi-asserted-by":"crossref","first-page":"S68","DOI":"10.1177\/088307388800300113","article-title":"Controversies in the treatment of autistic children: vitamin therapy","volume":"3","author":"Rimland","year":"1988","journal-title":"J Child Neurol"},{"key":"10.1016\/j.encep.2007.10.011_bib25","series-title":"Biological Treatment for Autism","article-title":"The use of vitamin B6, magnesium and DMG in the treatment of adults and children","author":"Rimland","year":"2002"},{"key":"10.1016\/j.encep.2007.10.011_bib26","doi-asserted-by":"crossref","first-page":"577","DOI":"10.3917\/psye.482.0577","article-title":"Autisme et gluten\u00a0: mythes et r\u00e9alit\u00e9s","volume":"48","author":"Robel","year":"2005","journal-title":"Psychiatr Enfant"},{"key":"10.1016\/j.encep.2007.10.011_bib27","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1111\/j.1600-0447.1993.tb03378.x","article-title":"Serotonin and amino acid content of platelets of autistic children","volume":"87","author":"Rolf","year":"1993","journal-title":"Acta Psychiatr Scand"},{"key":"10.1016\/j.encep.2007.10.011_bib28","first-page":"86","article-title":"Amino Acids and Infantile Autism","volume":"7","author":"Visconti","year":"1994","journal-title":"Dev Brain Dysfunct"},{"issue":"1","key":"10.1016\/j.encep.2007.10.011_bib29","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1046\/j.0021-9630.2003.00317.x","article-title":"Autism and pervasive developmental disorders","volume":"45","author":"Volkmar","year":"2004","journal-title":"J Child Psychol Psychiatry"},{"key":"10.1016\/j.encep.2007.10.011_bib30","series-title":"Healthcare for children on the autism spectrum disorder: a guide to medical, nutritional and behavioral issues","author":"Volkmar","year":"2004"},{"key":"10.1016\/j.encep.2007.10.011_bib31","first-page":"1","article-title":"Autisme, information biom\u00e9dicale et alliance th\u00e9rapeutique","volume":"33","author":"Sauvage","year":"2007","journal-title":"Enc\u00e9phale"}],"container-title":["L'Enc\u00e9phale"],"original-title":[],"language":"fr","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0013700607001509?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0013700607001509?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,12,30]],"date-time":"2018-12-30T21:26:15Z","timestamp":1546205175000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0013700607001509"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,10]]},"references-count":31,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2008,10]]}},"alternative-id":["S0013700607001509"],"URL":"https:\/\/doi.org\/10.1016\/j.encep.2007.10.011","relation":{},"ISSN":["0013-7006"],"issn-type":[{"value":"0013-7006","type":"print"}],"subject":[],"published":{"date-parts":[[2008,10]]}}}