{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T07:27:07Z","timestamp":1791185227378,"version":"4.1.0"},"reference-count":39,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2013,6,1]],"date-time":"2013-06-01T00:00:00Z","timestamp":1370044800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["L'Enc\u00e9phale"],"published-print":{"date-parts":[[2013,6]]},"DOI":"10.1016\/j.encep.2012.06.030","type":"journal-article","created":{"date-parts":[[2012,10,12]],"date-time":"2012-10-12T18:55:34Z","timestamp":1350068134000},"page":"149-154","source":"Crossref","is-referenced-by-count":7,"title":["Anomalies neurologiques et physiques mineures chez des patients pr\u00e9sentant un premier \u00e9pisode psychotique"],"prefix":"10.1016","volume":"39","author":[{"given":"A.","family":"Mhalla","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N.","family":"Boussa\u00efd","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.","family":"Gassab","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.","family":"Gaha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Mechri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"2","key":"10.1016\/j.encep.2012.06.030_bib0005","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/S0013-7006(04)95421-8","article-title":"L\u2019hypoth\u00e8se neurod\u00e9veloppementale dans la schizophr\u00e9nie","volume":"30","author":"Gourion","year":"2004","journal-title":"Enc\u00e9phale"},{"key":"10.1016\/j.encep.2012.06.030_bib0010","doi-asserted-by":"crossref","first-page":"879","DOI":"10.1016\/S0013-7006(06)76252-2","article-title":"Hypoth\u00e8se neurod\u00e9veloppementale de la schizophr\u00e9nie","volume":"32","author":"Thibaut","year":"2006","journal-title":"Enc\u00e9phale"},{"key":"10.1016\/j.encep.2012.06.030_bib0015","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1016\/j.comppsych.2007.07.005","article-title":"Expanding the schizophrenia phenotype: a composite evaluation of neurodevelopmental markers","volume":"49","author":"John","year":"2008","journal-title":"Compr Psychiatry"},{"key":"10.1016\/j.encep.2012.06.030_bib0020","doi-asserted-by":"crossref","first-page":"1298","DOI":"10.1176\/appi.ajp.160.7.1298","article-title":"Diagnostic specificity and neuroanatomical validity of neurological abnormalities in first-episode psychoses","volume":"160","author":"Keshavan","year":"2003","journal-title":"Am J Psychiatry"},{"key":"10.1016\/j.encep.2012.06.030_bib0025","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1016\/S0920-9964(99)00206-6","article-title":"Validation and factorial structure of a standardized neuroligical examination assessing neurological soft signs in schizophrenia","volume":"45","author":"Krebs","year":"2000","journal-title":"Schizophr Res"},{"key":"10.1016\/j.encep.2012.06.030_bib0030","doi-asserted-by":"crossref","first-page":"1157","DOI":"10.1016\/S0035-3787(07)78400-X","article-title":"Signes neurologiques mineurs et schizophr\u00e9nie\u00a0: revue des donn\u00e9es actuelles","volume":"163","author":"Krebs","year":"2007","journal-title":"Rev Neurol"},{"key":"10.1016\/j.encep.2012.06.030_bib0035","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1016\/j.encep.2007.08.009","article-title":"Signes neurologiques mineurs chez les patients schizophr\u00e8nes et leurs apparent\u00e9s non malades","volume":"34","author":"Mechri","year":"2008","journal-title":"Enc\u00e9phale"},{"issue":"2","key":"10.1016\/j.encep.2012.06.030_bib0040","first-page":"134","article-title":"Validation fran\u00e7aise d\u2019une \u00e9chelle d\u2019anomalies physiques mineures appliqu\u00e9e \u00e0 des patients schizophr\u00e8nes et \u00e0 leurs parents","volume":"27","author":"Gourion","year":"2001","journal-title":"Enc\u00e9phale"},{"key":"10.1016\/j.encep.2012.06.030_bib0045","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1176\/ajp.148.4.479","article-title":"Familial, obstetric, and other clinical correlates of minor physical anomalies in schizophrenia","volume":"148","author":"O\u2019Callaghan","year":"1991","journal-title":"Am J Psychiatry"},{"issue":"3","key":"10.1016\/j.encep.2012.06.030_bib0050","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1016\/j.ijdevneu.2010.10.006","article-title":"Minor physical anomalies: potentially informative vestiges of fetal developmental disruptions in schizophrenia","volume":"29","author":"Compton","year":"2011","journal-title":"Int J Dev Neurosci"},{"key":"10.1016\/j.encep.2012.06.030_bib0055","series-title":"Manuel diagnostique et statistique des troubles mentaux\u00a0: texte r\u00e9vis\u00e9","author":"American Psychiatric Association","year":"2003"},{"key":"10.1016\/j.encep.2012.06.030_bib0060","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1192\/bjp.158.2.171","article-title":"Pre-morbid adjustment and personality in psychosis effects of sex and diagnosis","volume":"158","author":"Foerster","year":"1991","journal-title":"Br J Psychiatry"},{"key":"10.1016\/j.encep.2012.06.030_bib0065","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1093\/schbul\/13.2.261","article-title":"The positive and negative syndrome scale (PANSS) for schizophrenia","volume":"13","author":"Kay","year":"1987","journal-title":"Schizophr Bull"},{"key":"10.1016\/j.encep.2012.06.030_bib0070","volume":"II","author":"Guelfi","year":"1997"},{"key":"10.1016\/j.encep.2012.06.030_bib0075","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1192\/bjp.181.43.s50","article-title":"Neurological soft signs in first-episode psychosis: systematic review","volume":"181","author":"Dazzan","year":"2002","journal-title":"Br J Psychiatry"},{"key":"10.1016\/j.encep.2012.06.030_bib0080","doi-asserted-by":"crossref","first-page":"1433","DOI":"10.1017\/S003329179900286X","article-title":"Determinants of neurological dysfunction in first-episode schizophrenia","volume":"30","author":"Browne","year":"2000","journal-title":"Psychol Med"},{"key":"10.1016\/j.encep.2012.06.030_bib0085","doi-asserted-by":"crossref","first-page":"2337","DOI":"10.1176\/appi.ajp.162.12.2337","article-title":"Neurological soft signs in first-episode schizophrenia: a follow-up study","volume":"162","author":"Bachmann","year":"2005","journal-title":"Am J Psychiatry"},{"key":"10.1016\/j.encep.2012.06.030_bib0090","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1192\/bjp.bp.107.045450","article-title":"Neurological abnormalities and cognitive ability in first-episode psychosis","volume":"193","author":"Dazzan","year":"2008","journal-title":"Br J Psychiatry"},{"key":"10.1016\/j.encep.2012.06.030_bib0095","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/j.schres.2004.06.014","article-title":"Neurological abnormalities in first-episode schizophrenia: temporal stability and clinical and outcome correlates","volume":"75","author":"Emsley","year":"2005","journal-title":"Schizophr Res"},{"issue":"1","key":"10.1016\/j.encep.2012.06.030_bib0100","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1017\/S0033291707001158","article-title":"Minor physical anomalies in patients with first-episode psychosis: their frequency and diagnostic specificity","volume":"38","author":"Lloyd","year":"2008","journal-title":"Psychol Med"},{"key":"10.1016\/j.encep.2012.06.030_bib0105","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1176\/appi.ajp.159.2.238","article-title":"Minor physical anomalies and schizophrenia spectrum disorders: a prospective investigation","volume":"159","author":"Schiffman","year":"2002","journal-title":"Am J Psychiatry"},{"issue":"5","key":"10.1016\/j.encep.2012.06.030_bib0110","doi-asserted-by":"crossref","first-page":"458","DOI":"10.1001\/archpsyc.59.5.458","article-title":"Minor physical anomalies and quantitative measures of the head and face in patients with psychosis","volume":"59","author":"McGrath","year":"2002","journal-title":"Arch Gen Psychiatry"},{"key":"10.1016\/j.encep.2012.06.030_bib0115","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1016\/j.schres.2006.08.019","article-title":"Minor physical anomalies across ethnic groups in a first episode psychosis sample","volume":"89","author":"Dean","year":"2007","journal-title":"Schizophr Res"},{"key":"10.1016\/j.encep.2012.06.030_bib0120","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/S0920-9964(03)00099-9","article-title":"Neurological and morphological anomalies and the genetic liability to schizophrenia: a composite phenotype","volume":"67","author":"Gourion","year":"2004","journal-title":"Schizophr Res"},{"issue":"1","key":"10.1016\/j.encep.2012.06.030_bib0125","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/j.psychres.2011.04.023","article-title":"Minor physical anomalies and neurological soft signs in patients with schizophrenia and their siblings","volume":"190","author":"Aksoy-Poyraz","year":"2011","journal-title":"Psychiatry Res"},{"key":"10.1016\/j.encep.2012.06.030_bib0130","first-page":"1","article-title":"Risk factors, pre-morbid functioning and episode correlates of neurological soft signs in drug-naive patients with schizophrenia-spectrum disorders","volume":"22","author":"Peralta","year":"2010","journal-title":"Psychol Med"},{"key":"10.1016\/j.encep.2012.06.030_bib0135","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/0920-9964(95)00016-X","article-title":"Minor physical anomalies in psychoses: associations with clinical and putative aetiological variables","volume":"18","author":"McGrath","year":"1995","journal-title":"Schizophr Res"},{"key":"10.1016\/j.encep.2012.06.030_bib0140","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1016\/j.schres.2008.08.001","article-title":"Fewer neurological soft signs among first episode psychosis patients with heavy cannabis use","volume":"107","author":"Ruiz-Veguilla","year":"2009","journal-title":"Schizophr Res"},{"key":"10.1016\/j.encep.2012.06.030_bib0145","doi-asserted-by":"crossref","first-page":"962","DOI":"10.1093\/schbul\/sbi028","article-title":"Significance and meaning of neurological signs in schizophrenia: two decades later","volume":"31","author":"Bombin","year":"2005","journal-title":"Schizophr Bull"},{"key":"10.1016\/j.encep.2012.06.030_bib0150","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1097\/01.yco.0000165599.90928.c7","article-title":"The psychopathology of schizophrenia and the presence of neurological soft signs: a review","volume":"18","author":"Tosato","year":"2005","journal-title":"Curr Opin Psychiatry"},{"key":"10.1016\/j.encep.2012.06.030_bib0155","first-page":"232","article-title":"Desorganisation syndrom is correlated to sensory neurological soft signs in medicated and neuroleptic naive schizophrenic patients","volume":"53","author":"Krebs","year":"2002","journal-title":"Schizophr Res"},{"key":"10.1016\/j.encep.2012.06.030_bib0160","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1016\/j.eurpsy.2008.04.003","article-title":"Neurodevelopmental markers in different psychopathological dimensions of first episode psychosis: the ESPIGAS study","volume":"23","author":"Ruiz-Veguilla","year":"2008","journal-title":"Eur Psychiatry"},{"key":"10.1016\/j.encep.2012.06.030_bib0165","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.schres.2011.09.015","article-title":"Neurological soft signs and gray matter changes: a longitudinal analysis in first-episode schizophrenia","volume":"134","author":"Kong","year":"2012","journal-title":"Schizophr Res"},{"issue":"6","key":"10.1016\/j.encep.2012.06.030_bib0170","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1111\/j.1600-0447.2010.01667.x","article-title":"Correlations of cerebello-thalamo-prefrontal structure and neurological soft signs in patient with first-episode psychosis","volume":"123","author":"Mouchet-Mages","year":"2011","journal-title":"Acta Psychiatr Scand"},{"issue":"3","key":"10.1016\/j.encep.2012.06.030_bib0175","doi-asserted-by":"crossref","first-page":"550","DOI":"10.1093\/schbul\/19.3.551","article-title":"Minor physical anomalies in schizophrenia and mood disorder","volume":"19","author":"Lohr","year":"1993","journal-title":"Schizophr Bull"},{"issue":"2","key":"10.1016\/j.encep.2012.06.030_bib0180","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1034\/j.1600-0447.2003.00116.x","article-title":"Association between minor physical anomalies and lateral ventricular enlargement in childhood and adolescent onset schizophrenia","volume":"108","author":"Hata","year":"2003","journal-title":"Acta Psychiatr Scand"},{"key":"10.1016\/j.encep.2012.06.030_bib0185","first-page":"383","article-title":"Les anomalies morphologiques mineures dans la schizophr\u00e9nie\u00a0: \u00e9tude d\u2019une population tunisienne","volume":"164","author":"K\u00e9bir","year":"2006","journal-title":"Ann Med Psychol"},{"issue":"2","key":"10.1016\/j.encep.2012.06.030_bib0190","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1007\/s00406-011-0219-1","article-title":"Characterization of spontaneous Parkinsonism in drug-naive patients with nonaffective psychotic disorders","volume":"262","author":"Peralta","year":"2012","journal-title":"Eur Arch Psychiatry Clin Neurosci"},{"key":"10.1016\/j.encep.2012.06.030_bib0195","doi-asserted-by":"crossref","DOI":"10.1016\/j.psychres.2012.03.008","article-title":"Dynamics of neurological soft signs and its relationship to clinical course in patients with first-episode schizophrenia","author":"Prikryl","year":"2012","journal-title":"Psychiatry Res"}],"container-title":["L'Enc\u00e9phale"],"original-title":[],"language":"fr","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0013700612001662?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0013700612001662?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,11,20]],"date-time":"2018-11-20T06:28:41Z","timestamp":1542695321000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0013700612001662"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,6]]},"references-count":39,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2013,6]]}},"alternative-id":["S0013700612001662"],"URL":"https:\/\/doi.org\/10.1016\/j.encep.2012.06.030","relation":{},"ISSN":["0013-7006"],"issn-type":[{"value":"0013-7006","type":"print"}],"subject":[],"published":{"date-parts":[[2013,6]]}}}