{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T18:52:30Z","timestamp":1778871150458,"version":"3.51.4"},"reference-count":87,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2020,4,1]],"date-time":"2020-04-01T00:00:00Z","timestamp":1585699200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,4,1]],"date-time":"2020-04-01T00:00:00Z","timestamp":1585699200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,4,6]],"date-time":"2021-04-06T00:00:00Z","timestamp":1617667200000},"content-version":"am","delay-in-days":370,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["L'Enc\u00e9phale"],"published-print":{"date-parts":[[2020,4]]},"DOI":"10.1016\/j.encep.2019.09.007","type":"journal-article","created":{"date-parts":[[2019,11,22]],"date-time":"2019-11-22T08:51:29Z","timestamp":1574412689000},"page":"123-134","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":9,"title":["Approche GABAergique de la d\u00e9pression du post-partum\u00a0: une revue critique translationnelle"],"prefix":"10.1016","volume":"46","author":[{"given":"J.","family":"Verbe","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Dubertret","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"W.","family":"El-Hage","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.","family":"Bonnet-Brilhault","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Duriez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.encep.2019.09.007_bib0440","article-title":"Clinique des d\u00e9pressions maternelles postnatales. EMC (Elsevier Masson SAS, Paris)","author":"Agboko","year":"2011","journal-title":"Psychiatrie"},{"key":"10.1016\/j.encep.2019.09.007_bib0445","series-title":"Psychopathologie de la p\u00e9rinatalit\u00e9","author":"Dayan","year":"2014"},{"issue":"2","key":"10.1016\/j.encep.2019.09.007_bib0450","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1192\/bjp.166.2.191","article-title":"Course and recurrence of postnatal depression. Evidence for the specificity of the diagnostic concept","volume":"166","author":"Cooper","year":"1995","journal-title":"Br J Psychiatry J Ment Sci"},{"issue":"3","key":"10.1016\/j.encep.2019.09.007_bib0455","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1007\/s00737-012-0323-x","article-title":"Examination of premenstrual symptoms as a risk factor for depression in postpartum women","volume":"16","author":"Buttner","year":"2013","journal-title":"Arch Womens Ment Health"},{"issue":"5","key":"10.1016\/j.encep.2019.09.007_bib0460","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1016\/S0272-7358(98)00100-7","article-title":"Maternal depression and parenting behavior: a meta-analytic review","volume":"20","author":"Lovejoy","year":"2000","journal-title":"Clin Psychol Rev"},{"key":"10.1016\/j.encep.2019.09.007_bib0465","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1093\/bmb\/ldg011","article-title":"Perinatal psychiatric disorders: a leading cause of maternal morbidity and mortality","volume":"67","author":"Oates","year":"2003","journal-title":"Br Med Bull"},{"issue":"6, Part 1","key":"10.1016\/j.encep.2019.09.007_bib0470","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1016\/j.lpm.2017.05.018","article-title":"Suicidalit\u00e9 en p\u00e9riode p\u00e9rinatale","volume":"46","author":"Guillard","year":"2017","journal-title":"Presse M\u00e9dicale"},{"issue":"8","key":"10.1016\/j.encep.2019.09.007_bib0475","doi-asserted-by":"crossref","first-page":"1673","DOI":"10.19082\/1673","article-title":"Cognitive Behavioral Development in Children Following Maternal Postpartum Depression: A Review Article","volume":"7","author":"Mirhosseini","year":"2015","journal-title":"Electron Physician"},{"issue":"3","key":"10.1016\/j.encep.2019.09.007_bib0480","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1007\/s00737-009-0066-5","article-title":"The impact of maternal psychopathology on child\u2013mother attachment","volume":"12","author":"Wan","year":"2009","journal-title":"Arch Womens Ment Health"},{"key":"10.1016\/j.encep.2019.09.007_bib0485","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.ejogrb.2016.04.032","article-title":"Postpartum practice: guidelines for clinical practice from the French College of Gynaecologists and Obstetricians (CNGOF)","volume":"202","author":"S\u00e9nat","year":"2016","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"issue":"6","key":"10.1016\/j.encep.2019.09.007_bib0490","doi-asserted-by":"crossref","first-page":"530","DOI":"10.1016\/j.jgyn.2007.06.004","article-title":"Th\u00e9rapeutique des troubles anxieux et d\u00e9pressifs de la grossesse et du post-partum. Revue et synth\u00e8se","volume":"36","author":"Dayan","year":"2007","journal-title":"J Gyn\u00e9cologie Obst\u00e9trique Biol Reprod"},{"issue":"4","key":"10.1016\/j.encep.2019.09.007_bib0495","article-title":"Antidepressants for preventing postnatal depression","author":"Molyneaux","year":"2018","journal-title":"Cochrane Database Syst Rev"},{"issue":"3","key":"10.1016\/j.encep.2019.09.007_bib0500","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1016\/j.yfrne.2009.05.006","article-title":"Neurosteroid biosynthesis: enzymatic pathways and neuroendocrine regulation by neurotransmitters and neuropeptides","volume":"30","author":"Do Rego","year":"2009","journal-title":"Front Neuroendocrinol"},{"issue":"1","key":"10.1016\/j.encep.2019.09.007_bib0505","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1196\/annals.1286.007","article-title":"Neurosteroid Biosynthesis in the Human Brain and Its Clinical Implications","volume":"1007","author":"Stoffel-Wagner","year":"2003","journal-title":"Ann N Y Acad Sci"},{"issue":"1","key":"10.1016\/j.encep.2019.09.007_bib0510","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1016\/j.neuropharm.2011.07.026","article-title":"Anxiety and depression: mouse genetics and pharmacological approaches to the role of GABA(A) receptor subtypes","volume":"62","author":"Smith","year":"2012","journal-title":"Neuropharmacology"},{"issue":"1","key":"10.1016\/j.encep.2019.09.007_bib0515","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1016\/j.neuropharm.2011.08.040","article-title":"The GABA system in anxiety and depression and its therapeutic potential","volume":"62","author":"M\u00f6hler","year":"2012","journal-title":"Neuropharmacology"},{"issue":"2","key":"10.1016\/j.encep.2019.09.007_bib0520","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1016\/0306-4522(87)90098-4","article-title":"GABAA and GABAB receptor site distribution in the rat central nervous system","volume":"20","author":"Bowery","year":"1987","journal-title":"Neuroscience"},{"issue":"3","key":"10.1016\/j.encep.2019.09.007_bib0525","doi-asserted-by":"crossref","first-page":"1040","DOI":"10.1523\/JNEUROSCI.12-03-01040.1992","article-title":"The distribution of 13\u00a0GABAA receptor subunit mRNAs in the rat brain. I. Telencephalon, diencephalon, mesencephalon","volume":"12","author":"Wisden","year":"1992","journal-title":"J Neurosci Off J Soc Neurosci"},{"issue":"2","key":"10.1016\/j.encep.2019.09.007_bib0530","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1002\/cne.24337","article-title":"GABAA receptor subunits in the human amygdala and hippocampus: immunohistochemical distribution of 7\u00a0subunits","volume":"526","author":"Stefanits","year":"2018","journal-title":"J Comp Neurol"},{"issue":"11","key":"10.1016\/j.encep.2019.09.007_bib0535","doi-asserted-by":"crossref","first-page":"986","DOI":"10.1038\/nsmb.3484","article-title":"Structural basis for GABAA receptor potentiation by neurosteroids","volume":"24","author":"Miller","year":"2017","journal-title":"Nat Struct Mol Biol"},{"issue":"4753","key":"10.1016\/j.encep.2019.09.007_bib0540","doi-asserted-by":"crossref","first-page":"1004","DOI":"10.1126\/science.2422758","article-title":"Steroid hormone metabolites are barbiturate-like modulators of the GABA receptor","volume":"232","author":"Majewska","year":"1986","journal-title":"Science"},{"issue":"17","key":"10.1016\/j.encep.2019.09.007_bib0545","doi-asserted-by":"crossref","first-page":"3333","DOI":"10.1007\/s00213-013-3423-z","article-title":"The role of ovarian hormone-derived neurosteroids on the regulation of GABAA receptors in affective disorders","volume":"231","author":"MacKenzie","year":"2014","journal-title":"Psychopharmacology (Berl)"},{"issue":"2","key":"10.1016\/j.encep.2019.09.007_bib0550","first-page":"135","article-title":"Does neurosteroid modulatory efficacy depend on GABAA receptor subunit composition?","volume":"1","author":"Puia","year":"1993","journal-title":"Receptors Channels"},{"issue":"22","key":"10.1016\/j.encep.2019.09.007_bib0555","doi-asserted-by":"crossref","first-page":"13284","DOI":"10.1073\/pnas.95.22.13284","article-title":"Role of brain allopregnanolone in the plasticity of -aminobutyric acid type A receptor in rat brain during pregnancy and after delivery","volume":"95","author":"Concas","year":"1998","journal-title":"Proc Natl Acad Sci"},{"key":"10.1016\/j.encep.2019.09.007_bib0560","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/j.brainres.2014.10.023","article-title":"Glutamate, GABA, and glutamine are synchronously upregulated in the mouse lateral septum during the postpartum period","volume":"1591","author":"Zhao","year":"2014","journal-title":"Brain Res"},{"issue":"8","key":"10.1016\/j.encep.2019.09.007_bib0565","doi-asserted-by":"crossref","first-page":"759","DOI":"10.1016\/j.euroneuro.2017.05.010","article-title":"Postpartum estrogen withdrawal impairs GABAergic inhibition and LTD induction in basolateral amygdala complex via down-regulation of GPR30","volume":"27","author":"Yang","year":"2017","journal-title":"Eur Neuropsychopharmacol"},{"key":"10.1016\/j.encep.2019.09.007_bib0570","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1016\/j.psyneuen.2017.12.003","article-title":"Inability to suppress the stress-induced activation of the HPA axis during the peripartum period engenders deficits in postpartum behaviors in mice","volume":"90","author":"Mel\u00f3n","year":"2018","journal-title":"Psychoneuroendocrinology"},{"issue":"10","key":"10.1016\/j.encep.2019.09.007_bib0575","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1111\/jne.12188","article-title":"Emotion and Mood Adaptations in the Peripartum Female: Complementary Contributions of GABA and Oxytocin","volume":"26","author":"Lonstein","year":"2014","journal-title":"J Neuroendocrinol"},{"issue":"Suppl 1","key":"10.1016\/j.encep.2019.09.007_bib0580","doi-asserted-by":"crossref","first-page":"S84","DOI":"10.1016\/j.psyneuen.2009.06.019","article-title":"Steroid Hormone Fluctuations and GABAAR Plasticity","volume":"34","author":"Maguire","year":"2009","journal-title":"Psychoneuroendocrinology"},{"issue":"2","key":"10.1016\/j.encep.2019.09.007_bib0585","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1016\/j.neuron.2008.06.019","article-title":"GABAAR plasticity during pregnancy: relevance to postpartum depression","volume":"59","author":"Maguire","year":"2008","journal-title":"Neuron"},{"key":"10.1016\/j.encep.2019.09.007_bib0590","doi-asserted-by":"crossref","DOI":"10.3389\/fncir.2013.00144","article-title":"Altered gamma oscillations during pregnancy through loss of (subunit-containing GABAA receptors on parvalbumin interneurons","volume":"7","author":"Ferando","year":"2013","journal-title":"Front Neural Circuits"},{"issue":"4","key":"10.1016\/j.encep.2019.09.007_bib0595","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1016\/j.pbb.2007.05.017","article-title":"Inhibition of progesterone metabolism mimics the effect of progesterone withdrawal on forced swim test immobility","volume":"87","author":"Beckley","year":"2007","journal-title":"Pharmacol Biochem Behav"},{"issue":"3","key":"10.1016\/j.encep.2019.09.007_bib0600","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1016\/j.pbb.2004.03.024","article-title":"Hippocampal 3alpha, 5alpha-THP may alter depressive behavior of pregnant and lactating rats","volume":"78","author":"Frye","year":"2004","journal-title":"Pharmacol Biochem Behav"},{"issue":"3","key":"10.1016\/j.encep.2019.09.007_bib0605","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1016\/S0010-440X(03)00034-8","article-title":"Endocrine factors in the etiology of postpartum depression","volume":"44","author":"Bloch","year":"2003","journal-title":"Compr Psychiatry"},{"issue":"6679","key":"10.1016\/j.encep.2019.09.007_bib0610","doi-asserted-by":"crossref","first-page":"926","DOI":"10.1038\/31948","article-title":"GABA(A) receptor alpha4\u00a0subunit suppression prevents withdrawal properties of an endogenous steroid","volume":"392","author":"Smith","year":"1998","journal-title":"Nature"},{"issue":"4","key":"10.1016\/j.encep.2019.09.007_bib0615","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1016\/j.biopsych.2008.03.029","article-title":"A Postpartum Model in Rat: Behavioral and Gene Expression Changes Induced by Ovarian Steroid Deprivation","volume":"64","author":"Suda","year":"2008","journal-title":"Biol Psychiatry"},{"issue":"4","key":"10.1016\/j.encep.2019.09.007_bib0620","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1016\/j.pbb.2010.03.007","article-title":"GABA(A) receptor antagonism in the ventrocaudal periaqueductal gray increases anxiety in the anxiety-resistant postpartum rat","volume":"95","author":"Miller","year":"2010","journal-title":"Pharmacol Biochem Behav"},{"issue":"6","key":"10.1016\/j.encep.2019.09.007_bib0625","doi-asserted-by":"crossref","first-page":"824","DOI":"10.1016\/j.psyneuen.2010.11.004","article-title":"Progesterone receptor antagonist CDB-4124\u00a0increases depression-like behavior in mice without affecting locomotor ability","volume":"36","author":"Beckley","year":"2011","journal-title":"Psychoneuroendocrinology"},{"key":"10.1016\/j.encep.2019.09.007_bib0630","doi-asserted-by":"crossref","DOI":"10.1186\/s13041-018-0355-x","article-title":"Antidepressant-like effects of translocator protein (18\u00a0kDa) ligand ZBD-2\u00a0in mouse models of postpartum depression","volume":"11","author":"Li","year":"2018","journal-title":"Mol Brain"},{"key":"10.1016\/j.encep.2019.09.007_bib0635","doi-asserted-by":"crossref","first-page":"703","DOI":"10.3389\/fendo.2018.00703","article-title":"A Novel, Synthetic, Neuroactive Steroid Is Effective at Decreasing Depression-Like Behaviors and Improving Maternal Care in Preclinical Models of Postpartum Depression","volume":"9","author":"Mel\u00f3n","year":"2018","journal-title":"Front Endocrinol"},{"issue":"2","key":"10.1016\/j.encep.2019.09.007_bib0640","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1016\/j.euroneuro.2006.02.006","article-title":"The progesterone metabolite allopregnanolone potentiates GABAA receptor-mediated inhibition of 5-HT neuronal activity","volume":"17","author":"Kaura","year":"2007","journal-title":"Eur Neuropsychopharmacol"},{"issue":"6","key":"10.1016\/j.encep.2019.09.007_bib0645","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1016\/j.biopsych.2004.06.002","article-title":"Changes in cerebrospinal fluid neurochemistry during pregnancy","volume":"56","author":"Altemus","year":"2004","journal-title":"Biol Psychiatry"},{"issue":"3","key":"10.1016\/j.encep.2019.09.007_bib0650","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1007\/s40263-019-00605-7","article-title":"Pharmacotherapy of Postpartum Depression: Current Approaches and Novel Drug Development","volume":"33","author":"Frieder","year":"2019","journal-title":"CNS Drugs"},{"key":"10.1016\/j.encep.2019.09.007_bib0655","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/j.yfrne.2018.12.001","article-title":"Pathophysiological mechanisms implicated in postpartum depression","volume":"52","author":"Payne","year":"2019","journal-title":"Front Neuroendocrinol"},{"issue":"4","key":"10.1016\/j.encep.2019.09.007_bib0660","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1016\/j.pbb.2006.06.007","article-title":"The interaction of neuroactive steroids and GABA in the development of neuropsychiatric disorders in women","volume":"84","author":"Amin","year":"2006","journal-title":"Pharmacol Biochem Behav"},{"issue":"5","key":"10.1016\/j.encep.2019.09.007_bib0665","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1080\/09513590500361747","article-title":"3\u03b1-reduced neuroactive steroids and their precursors during pregnancy and the postpartum period","volume":"21","author":"Gilbert Evans","year":"2005","journal-title":"Gynecol Endocrinol"},{"issue":"3","key":"10.1016\/j.encep.2019.09.007_bib0670","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1007\/s00213-006-0313-7","article-title":"Preliminary evidence of reduced occipital GABA concentrations in puerperal women: a 1H-MRS study","volume":"186","author":"Epperson","year":"2006","journal-title":"Psychopharmacology (Berl)"},{"issue":"6","key":"10.1016\/j.encep.2019.09.007_bib0675","doi-asserted-by":"crossref","first-page":"924","DOI":"10.1176\/appi.ajp.157.6.924","article-title":"Effects of Gonadal Steroids in Women With a History of Postpartum Depression","volume":"157","author":"Bloch","year":"2000","journal-title":"Am J Psychiatry"},{"issue":"9","key":"10.1016\/j.encep.2019.09.007_bib0680","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1007\/s11920-018-0937-4","article-title":"Neuroactive Steroids and Perinatal Depression: a Review of Recent Literature","volume":"20","author":"McEvoy","year":"2018","journal-title":"Curr Psychiatry Rep"},{"key":"10.1016\/j.encep.2019.09.007_bib0685","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1016\/j.yhbeh.2017.06.008","article-title":"Allopregnanolone levels and depressive symptoms during pregnancy in relation to single nucleotide polymorphisms in the allopregnanolone synthesis pathway","volume":"94","author":"Hellgren","year":"2017","journal-title":"Horm Behav"},{"issue":"6","key":"10.1016\/j.encep.2019.09.007_bib0690","doi-asserted-by":"crossref","first-page":"816","DOI":"10.1016\/j.jpsychires.2013.02.010","article-title":"GABAergic Neuroactive Steroids and Resting-State Functional Connectivity in Postpartum Depression: A Preliminary Study","volume":"47","author":"Deligiannidis","year":"2013","journal-title":"J Psychiatr Res"},{"issue":"3","key":"10.1016\/j.encep.2019.09.007_bib0695","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1159\/000358838","article-title":"Low Serum Allopregnanolone Is Associated with Symptoms of Depression in Late Pregnancy","volume":"69","author":"Hellgren","year":"2014","journal-title":"Neuropsychobiology"},{"key":"10.1016\/j.encep.2019.09.007_bib0700","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1016\/j.psyneuen.2017.02.012","article-title":"Lower Allopregnanolone during Pregnancy Predicts Postpartum Depression: An Exploratory Study","volume":"79","author":"Osborne","year":"2017","journal-title":"Psychoneuroendocrinology"},{"key":"10.1016\/j.encep.2019.09.007_bib0705","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1016\/j.psyneuen.2016.05.010","article-title":"Peripartum neuroactive steroid and \u03b3-aminobutyric acid profiles in women at-risk for postpartum depression","volume":"70","author":"Deligiannidis","year":"2016","journal-title":"Psychoneuroendocrinology"},{"issue":"7","key":"10.1016\/j.encep.2019.09.007_bib0710","doi-asserted-by":"crossref","first-page":"1299","DOI":"10.1007\/s00213-016-4217-x","article-title":"Blunted neuroactive steroid and HPA axis responses to stress are associated with reduced sleep quality and negative affect in pregnancy: a pilot study","volume":"233","author":"Crowley","year":"2016","journal-title":"Psychopharmacology (Berl)"},{"key":"10.1016\/j.encep.2019.09.007_bib0715","article-title":"GABAA dysregulation as an explanatory model for late-onset postpartum depression associated with weaning and resumption of menstruation","author":"Burke","year":"2018","journal-title":"Arch Womens Ment Health"},{"issue":"1","key":"10.1016\/j.encep.2019.09.007_bib0720","first-page":"77","article-title":"Serum allopregnanolone in women with postpartum \u201cblues\u201d","volume":"97","author":"Nappi","year":"2001","journal-title":"Obstet Gynecol"},{"issue":"3","key":"10.1016\/j.encep.2019.09.007_bib0725","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1038\/s41386-018-0242-2","article-title":"Resting-state functional connectivity, cortical GABA, and neuroactive steroids in peripartum and peripartum depressed women: a functional magnetic resonance imaging and spectroscopy study","volume":"44","author":"Deligiannidis","year":"2018","journal-title":"Neuropsychopharmacology"},{"issue":"6","key":"10.1016\/j.encep.2019.09.007_bib0730","doi-asserted-by":"crossref","first-page":"1648","DOI":"10.1038\/npp.2015.333","article-title":"Replication of Epigenetic Postpartum Depression Biomarkers and Variation with Hormone Levels","volume":"41","author":"Osborne","year":"2016","journal-title":"Neuropsychopharmacology"},{"issue":"5","key":"10.1016\/j.encep.2019.09.007_bib0735","doi-asserted-by":"crossref","first-page":"560","DOI":"10.1038\/mp.2013.62","article-title":"Antenatal prediction of postpartum depression with blood DNA methylation biomarkers","volume":"19","author":"Guintivano","year":"2014","journal-title":"Mol Psychiatry"},{"issue":"2","key":"10.1016\/j.encep.2019.09.007_bib0740","doi-asserted-by":"crossref","DOI":"10.1002\/hup.2576","article-title":"Open-label, proof of concept study of brexanolone in the treatment of severe postpartum depression","volume":"32","author":"Kanes","year":"2017","journal-title":"Hum Psychopharmacol"},{"issue":"10093","key":"10.1016\/j.encep.2019.09.007_bib0745","doi-asserted-by":"crossref","first-page":"480","DOI":"10.1016\/S0140-6736(17)31264-3","article-title":"Brexanolone (SAGE-547\u00a0injection) in post-partum depression: a randomised controlled trial","volume":"390","author":"Kanes","year":"2017","journal-title":"The Lancet"},{"issue":"10152","key":"10.1016\/j.encep.2019.09.007_bib0750","doi-asserted-by":"crossref","first-page":"1058","DOI":"10.1016\/S0140-6736(18)31551-4","article-title":"Brexanolone injection in post-partum depression: two multicentre, double-blind, randomised, placebo-controlled, phase 3\u00a0trials","volume":"392","author":"Meltzer-Brody","year":"2018","journal-title":"The Lancet"},{"issue":"1\u20132","key":"10.1016\/j.encep.2019.09.007_bib0755","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.cell.2018.12.016","article-title":"GABAAR Modulator for Postpartum Depression","volume":"176","author":"Mody","year":"2019","journal-title":"Cell"},{"key":"10.1016\/j.encep.2019.09.007_bib0760","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/j.psychres.2019.07.006","article-title":"Brexanolone for postpartum depression: A meta-analysis of randomized controlled studies","volume":"279","author":"Zheng","year":"2019","journal-title":"Psychiatry Res"},{"key":"10.1016\/j.encep.2019.09.007_bib0765","article-title":"SAGE-217, A Novel GABAA Receptor Positive Allosteric Modulator: Clinical Pharmacology and Tolerability in Randomized Phase I Dose-Finding Studies","author":"Hoffmann","year":"2019","journal-title":"Clin Pharmacokinet"},{"issue":"5","key":"10.1016\/j.encep.2019.09.007_bib0770","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1016\/j.genhosppsych.2009.04.003","article-title":"The management of depression during pregnancy: a report from the American Psychiatric Association and the American College of Obstetricians and Gynecologists","volume":"31","author":"Yonkers","year":"2009","journal-title":"Gen Hosp Psychiatry"},{"key":"10.1016\/j.encep.2019.09.007_bib0775","article-title":"Brexanolone, a neurosteroid antidepressant, vindicates the GABAergic deficit hypothesis of depression and may foster resilience. F1000","author":"L\u00fcscher","year":"2019","journal-title":"Research"},{"key":"10.1016\/j.encep.2019.09.007_bib0780","doi-asserted-by":"crossref","first-page":"83","DOI":"10.3389\/fncel.2019.00083","article-title":"Neuroactive Steroids and GABAergic Involvement in the Neuroendocrine Dysfunction Associated With Major Depressive Disorder and Postpartum Depression","volume":"13","author":"Maguire","year":"2019","journal-title":"Front Cell Neurosci"},{"issue":"7","key":"10.1016\/j.encep.2019.09.007_bib0785","doi-asserted-by":"crossref","first-page":"779","DOI":"10.1007\/s40265-019-01121-0","article-title":"Brexanolone: First Global Approval","volume":"79","author":"Scott","year":"2019","journal-title":"Drugs"},{"key":"10.1016\/j.encep.2019.09.007_bib0790","series-title":"Brexanolone","author":"Azhar","year":"2019"},{"issue":"2","key":"10.1016\/j.encep.2019.09.007_bib0795","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1007\/s00213-013-3276-5","article-title":"Neurosteroid interactions with synaptic and extrasynaptic GABA(A) receptors: regulation of subunit plasticity, phasic and tonic inhibition, and neuronal network excitability","volume":"230","author":"Carver","year":"2013","journal-title":"Psychopharmacology (Berl)"},{"issue":"8\u20139","key":"10.1016\/j.encep.2019.09.007_bib0800","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1051\/medsci\/20072389751","article-title":"Un transmetteur pionnier pour la construction du cerveau","volume":"23","author":"Ben-Ari","year":"2007","journal-title":"M\u00e9decine\/sciences"},{"key":"10.1016\/j.encep.2019.09.007_bib0805","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/j.neuroscience.2014.08.001","article-title":"The GABA excitatory\/inhibitory developmental sequence: a personal journey","volume":"279","author":"Ben-Ari","year":"2014","journal-title":"Neuroscience"},{"issue":"516","key":"10.1016\/j.encep.2019.09.007_bib0810","doi-asserted-by":"crossref","first-page":"1325","DOI":"10.1192\/bjp.114.516.1325","article-title":"Atypical Depression Following Childbirth","volume":"114","author":"Pitt","year":"1968","journal-title":"Br J Psychiatry"},{"key":"10.1016\/j.encep.2019.09.007_bib0815","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/j.jad.2016.07.044","article-title":"Prevalence of paternal depression in pregnancy and the postpartum: an updated meta-analysis","volume":"206","author":"Cameron","year":"2016","journal-title":"J Affect Disord"},{"issue":"19","key":"10.1016\/j.encep.2019.09.007_bib0820","doi-asserted-by":"crossref","first-page":"1961","DOI":"10.1001\/jama.2010.605","article-title":"Prenatal and Postpartum Depression in Fathers and Its Association With Maternal Depression: A Meta-analysis","volume":"303","author":"Paulson","year":"2010","journal-title":"JAMA"},{"issue":"4","key":"10.1016\/j.encep.2019.09.007_bib0825","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1007\/s00737-016-0598-4","article-title":"The course and interrelationship of maternal and paternal perinatal depression","volume":"19","author":"Paulson","year":"2016","journal-title":"Arch Womens Ment Health"},{"issue":"6","key":"10.1016\/j.encep.2019.09.007_bib0830","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1016\/j.pedhc.2012.10.001","article-title":"Paternal Postpartum Depression: What Health Care Providers Should Know","volume":"27","author":"Musser","year":"2013","journal-title":"J Pediatr Health Care"},{"key":"10.1016\/j.encep.2019.09.007_bib0835","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1016\/j.jad.2019.02.033","article-title":"A prospective study of postnatal depressive symptoms and associated risk factors in first-time fathers","volume":"249","author":"Da Costa","year":"2019","journal-title":"J Affect Disord"},{"key":"10.1016\/j.encep.2019.09.007_bib0840","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1016\/j.jad.2016.01.049","article-title":"Post-adoption depression: parental classes of depressive symptoms across time","volume":"200","author":"Foli","year":"2016","journal-title":"J Affect Disord"},{"issue":"1\u20132","key":"10.1016\/j.encep.2019.09.007_bib0845","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1016\/j.jad.2008.09.002","article-title":"Post-adoption depression among adoptive mothers","volume":"115","author":"Senecky","year":"2009","journal-title":"J Affect Disord"},{"issue":"2","key":"10.1016\/j.encep.2019.09.007_bib0850","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1007\/s00737-009-0137-7","article-title":"Post adoption depression","volume":"13","author":"Fields","year":"2010","journal-title":"Arch Womens Ment Health"},{"issue":"4","key":"10.1016\/j.encep.2019.09.007_bib0855","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1016\/j.pbb.2010.03.007","article-title":"GABAA receptor antagonism in the ventrocaudal periaqueductal gray increases anxiety in the anxiety-resistant postpartum rat","volume":"95","author":"Miller","year":"2010","journal-title":"Pharmacol Biochem Behav"},{"issue":"5","key":"10.1016\/j.encep.2019.09.007_bib0860","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1080\/09513590500361747","article-title":"3\u03b1-reduced neuroactive steroids and their precursors during pregnancy and the postpartum period","volume":"21","author":"Gilbert Evans","year":"2005","journal-title":"Gynecol Endocrinol"},{"issue":"1","key":"10.1016\/j.encep.2019.09.007_bib0865","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1017\/S1092852914000480","article-title":"The Role of Reproductive Hormones in Postpartum Depression","volume":"20","author":"Schiller","year":"2015","journal-title":"CNS Spectr"},{"issue":"17","key":"10.1016\/j.encep.2019.09.007_bib0870","doi-asserted-by":"crossref","first-page":"3557","DOI":"10.1007\/s00213-014-3599-x","article-title":"Allopregnanolone as a mediator of affective switching in reproductive mood disorders","volume":"231","author":"Schiller","year":"2014","journal-title":"Psychopharmacology (Berl)"}],"container-title":["L'Enc\u00e9phale"],"original-title":[],"language":"fr","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0013700619302763?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0013700619302763?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,15]],"date-time":"2025-09-15T17:37:21Z","timestamp":1757957841000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0013700619302763"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,4]]},"references-count":87,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2020,4]]}},"alternative-id":["S0013700619302763"],"URL":"https:\/\/doi.org\/10.1016\/j.encep.2019.09.007","relation":{},"ISSN":["0013-7006"],"issn-type":[{"value":"0013-7006","type":"print"}],"subject":[],"published":{"date-parts":[[2020,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Approche GABAergique de la d\u00e9pression du post-partum\u00a0: une revue critique translationnelle","name":"articletitle","label":"Article Title"},{"value":"L'Enc\u00e9phale","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.encep.2019.09.007","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 L'Enc\u00e9phale, Paris.","name":"copyright","label":"Copyright"}]}}