{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,2]],"date-time":"2026-08-02T19:53:32Z","timestamp":1785700412818,"version":"3.56.0"},"reference-count":71,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T00:00:00Z","timestamp":1785369600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100020913","name":"French Military Health Service","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100020913","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100022863","name":"Statistical Society of Australia","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100022863","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["L'Enc\u00e9phale"],"published-print":{"date-parts":[[2026,8]]},"DOI":"10.1016\/j.encep.2026.01.004","type":"journal-article","created":{"date-parts":[[2026,3,15]],"date-time":"2026-03-15T12:12:03Z","timestamp":1773576723000},"page":"423-432","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Management of trauma-related nightmares in PTSD: Can doxazosin serve as a pragmatic alternative to prazosin?"],"prefix":"10.1016","volume":"52","author":[{"given":"Gilles","family":"Sipahimalani","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Baptiste","family":"Roseau","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dorone","family":"Feingold","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marion","family":"Remadi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chlo\u00e9","family":"Lhermitte","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sonia","family":"Houssany-Pissot","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Doroth\u00e9e","family":"Defontaine","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fr\u00e9d\u00e9rique","family":"Gignoux-Froment","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sophie","family":"Annette","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emeric","family":"Saguin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"4","key":"10.1016\/j.encep.2026.01.004_bib0360","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1016\/j.smrv.2007.03.004","article-title":"Nightmares: a new neurocognitive model","volume":"11","author":"Nielsen","year":"2007","journal-title":"Sleep Med Rev"},{"key":"10.1016\/j.encep.2026.01.004_bib0365","series-title":"Treating post-trauma nightmares: a cognitive behavioral approach","author":"Davis","year":"2008"},{"issue":"1","key":"10.1016\/j.encep.2026.01.004_bib0370","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.encep.2022.10.002","article-title":"Clinical description of sleep and trauma-related nightmares in a population of French active-duty members and veterans with PTSD","volume":"50","author":"Hulot","year":"2024","journal-title":"Enc\u00e9phale"},{"issue":"10","key":"10.1016\/j.encep.2026.01.004_bib0375","doi-asserted-by":"crossref","first-page":"1310","DOI":"10.3390\/brainsci11101310","article-title":"Sleep and PTSD in the military forces: a reciprocal relationship and a psychiatric approach","volume":"11","author":"Saguin","year":"2021","journal-title":"Brain Sci"},{"key":"10.1016\/j.encep.2026.01.004_bib0380","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1016\/j.smrv.2017.01.004","article-title":"Trauma-associated sleep disorder: a parasomnia induced by trauma","volume":"37","author":"Mysliwiec","year":"2018","journal-title":"Sleep Med Rev"},{"issue":"1","key":"10.1016\/j.encep.2026.01.004_bib0385","doi-asserted-by":"crossref","first-page":"zpae099","DOI":"10.1093\/sleepadvances\/zpae099","article-title":"Distressing dreams in trauma survivors: using a sleep diary mobile app to reveal distressing dream characteristics and their relationship to symptoms and suicidal ideation in trauma-exposed adults","volume":"6","author":"Richards","year":"2025","journal-title":"Sleep Adv"},{"key":"10.1016\/j.encep.2026.01.004_bib0390","doi-asserted-by":"crossref","first-page":"8011375","DOI":"10.1155\/da\/8011375","article-title":"PTSD symptom severity associated with sleep disturbances in military personnel: evidence from a prospective controlled study with ecological recordings","volume":"2025","author":"Saguin","year":"2025","journal-title":"Depress Anxiety"},{"issue":"4","key":"10.1016\/j.encep.2026.01.004_bib0395","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1176\/appi.ajp.2012.12040432","article-title":"Sleep disturbances as the hallmark of PTSD: where are we now?","volume":"170","author":"Germain","year":"2013","journal-title":"Am J Psychiatry"},{"issue":"6","key":"10.1016\/j.encep.2026.01.004_bib0400","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1016\/j.jpsychores.2013.09.004","article-title":"Longitudinal relationships of insomnia, nightmares, and PTSD severity in recent combat veterans","volume":"75","author":"Pigeon","year":"2013","journal-title":"J Psychosom Res"},{"key":"10.1016\/j.encep.2026.01.004_bib0405","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1016\/j.sleep.2023.01.024","article-title":"An ecological approach to clinically assess nightmares in military service members with severe PTSD","volume":"103","author":"Saguin","year":"2023","journal-title":"Sleep Med"},{"issue":"5","key":"10.1016\/j.encep.2026.01.004_bib0410","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1037\/a0016570","article-title":"Overnight therapy? The role of sleep in emotional brain processing","volume":"135","author":"Van der Helm","year":"2009","journal-title":"Psychol Bull"},{"issue":"1","key":"10.1016\/j.encep.2026.01.004_bib0415","doi-asserted-by":"crossref","DOI":"10.1093\/sleep\/zsx188","article-title":"An ambulatory polysomnography study of the post-traumatic nightmares of post-traumatic stress disorder","volume":"41","author":"Phelps","year":"2018","journal-title":"Sleep"},{"issue":"2","key":"10.1016\/j.encep.2026.01.004_bib0420","doi-asserted-by":"crossref","first-page":"e13639","DOI":"10.1111\/jsr.13639","article-title":"The sleep physiology of nightmares in veterans with psychological trauma: evaluation of a dominant model using participant-applied electroencephalography in the home environment","volume":"32","author":"Richards","year":"2023","journal-title":"J Sleep Res"},{"issue":"2","key":"10.1016\/j.encep.2026.01.004_bib0425","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1016\/j.cpr.2007.06.001","article-title":"Understanding posttraumatic nightmares: an empirical and conceptual review","volume":"28","author":"Phelps","year":"2008","journal-title":"Clin Psychol Rev"},{"key":"10.1016\/j.encep.2026.01.004_bib0430","series-title":"Le r\u00eave\u00a0: un territoire \u00e0 explorer","article-title":"Le cauchemar traumatique","author":"Saguin","year":"2023"},{"issue":"1","key":"10.1016\/j.encep.2026.01.004_bib0435","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1080\/15299732.2016.1191578","article-title":"Preliminary validation of a brief measure of the frequency and severity of nightmares: the trauma-related nightmare survey","volume":"18","author":"Cranston","year":"2017","journal-title":"J Trauma Dissociation"},{"issue":"9\u201310","key":"10.1016\/j.encep.2026.01.004_bib0440","doi-asserted-by":"crossref","first-page":"3182","DOI":"10.1093\/milmed\/usac107","article-title":"Translation, cross-cultural adaptation and preliminary validation of a French version of the trauma-related nightmare survey (TRNS-FR) in a PTSD veteran population","volume":"188","author":"Saguin","year":"2023","journal-title":"Mil Med"},{"issue":"1","key":"10.1016\/j.encep.2026.01.004_bib0445","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1016\/j.encep.2023.01.004","article-title":"Evaluation of sleep and therapeutic education needs of military with PTSD","volume":"50","author":"Remadi","year":"2024","journal-title":"Enc\u00e9phale"},{"issue":"5","key":"10.1016\/j.encep.2026.01.004_bib0450","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1001\/jama.286.5.537","article-title":"Imagery rehearsal therapy for chronic nightmares in sexual assault survivors with posttraumatic stress disorder: a randomized controlled trial","volume":"286","author":"Krakow","year":"2001","journal-title":"JAMA"},{"issue":"4","key":"10.1016\/j.encep.2026.01.004_bib0455","first-page":"517","article-title":"Treatment for nightmares by imagery rehearsal therapy (or IRT): practical implementation","volume":"17","author":"Stern","year":"2022","journal-title":"Sleep Med Clin"},{"issue":"4","key":"10.1016\/j.encep.2026.01.004_bib0460","doi-asserted-by":"crossref","first-page":"389","DOI":"10.5664\/jcsm.27883","article-title":"Best practice guide for the treatment of nightmare disorder in adults","volume":"6","author":"Aurora","year":"2010","journal-title":"J Clin Sleep Med"},{"issue":"6","key":"10.1016\/j.encep.2026.01.004_bib0465","doi-asserted-by":"crossref","first-page":"1041","DOI":"10.5664\/jcsm.7178","article-title":"Position paper for the treatment of nightmare disorder in adults: an American Academy of Sleep Medicine position paper","volume":"14","author":"Morgenthaler","year":"2018","journal-title":"J Clin Sleep Med"},{"issue":"6","key":"10.1016\/j.encep.2026.01.004_bib0470","doi-asserted-by":"crossref","first-page":"566","DOI":"10.1016\/j.cpr.2012.06.002","article-title":"A meta-analysis of imagery rehearsal for post-trauma nightmares: effects on nightmare frequency, sleep quality, and posttraumatic stress","volume":"32","author":"Casement","year":"2012","journal-title":"Clin Psychol Rev"},{"key":"10.1016\/j.encep.2026.01.004_bib0475","doi-asserted-by":"crossref","first-page":"101248","DOI":"10.1016\/j.smrv.2019.101248","article-title":"Comparative efficacy of imagery rehearsal therapy and prazosin in the treatment of trauma-related nightmares in adults: a meta-analysis of randomized controlled trials","volume":"50","author":"Y\u00fccel","year":"2020","journal-title":"Sleep Med Rev"},{"issue":"5","key":"10.1016\/j.encep.2026.01.004_bib0480","doi-asserted-by":"crossref","first-page":"757","DOI":"10.5664\/jcsm.7770","article-title":"Randomized controlled trial of imagery rehearsal for posttraumatic nightmares in combat veterans","volume":"15","author":"Harb","year":"2019","journal-title":"J Clin Sleep Med"},{"key":"10.1016\/j.encep.2026.01.004_bib0485","first-page":"2","article-title":"Troubles psychiques en relation avec un \u00e9v\u00e9nement traumatisant dans les arm\u00e9es\u00a0: facteurs associ\u00e9s aux conduites addictives et \u00e0 la prise en charge psychiatrique avant la d\u00e9claration","volume":"4","author":"Wardat","year":"2014","journal-title":"Bull Epidemiol Armees"},{"issue":"12","key":"10.1016\/j.encep.2026.01.004_bib0490","doi-asserted-by":"crossref","first-page":"2043","DOI":"10.1176\/appi.ajp.158.12.2043","article-title":"An open-label trial of evidence-based cognitive behavior therapy for nightmares and insomnia in crime victims with PTSD","volume":"158","author":"Krakow","year":"2001","journal-title":"Am J Psychiatry"},{"issue":"1","key":"10.1016\/j.encep.2026.01.004_bib0495","doi-asserted-by":"crossref","first-page":"100658","DOI":"10.1016\/j.ijchp.2025.100658","article-title":"Imagery rehearsal therapy (IRT) is associated with reduced nightmare severity and depressive, anxiety and suicidal symptoms in adults with major depressive episode","volume":"26","author":"Maruani","year":"2026","journal-title":"Int J Clin Health Psychol"},{"issue":"6","key":"10.1016\/j.encep.2026.01.004_bib0500","doi-asserted-by":"crossref","first-page":"e13860","DOI":"10.1111\/jsr.13860","article-title":"Mechanisms of cognitive behavioural therapy for insomnia","volume":"32","author":"Altena","year":"2023","journal-title":"J Sleep Res"},{"issue":"2","key":"10.1016\/j.encep.2026.01.004_bib0505","doi-asserted-by":"crossref","first-page":"327","DOI":"10.5665\/sleep.3408","article-title":"Cognitive behavioral therapy for insomnia in posttraumatic stress disorder: a randomized controlled trial","volume":"37","author":"Talbot","year":"2014","journal-title":"Sleep"},{"key":"10.1016\/j.encep.2026.01.004_bib0510","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1016\/j.cpr.2015.09.005","article-title":"Cognitive-behavioral therapy for sleep disturbances in treating posttraumatic stress disorder symptoms: a meta-analysis of randomized controlled trials","volume":"43","author":"Ho","year":"2016","journal-title":"Clin Psychol Rev"},{"issue":"7","key":"10.1016\/j.encep.2026.01.004_bib0515","doi-asserted-by":"crossref","first-page":"1193","DOI":"10.5664\/jcsm.7224","article-title":"Cognitive behavioral therapy for insomnia reduces fear of sleep in individuals with posttraumatic stress disorder","volume":"14","author":"Kanady","year":"2018","journal-title":"J Clin Sleep Med"},{"issue":"2","key":"10.1016\/j.encep.2026.01.004_bib0520","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1002\/jts.20015","article-title":"Treatment of residual insomnia after CBT for PTSD: case studies","volume":"18","author":"DeViva","year":"2005","journal-title":"J Trauma Stress"},{"issue":"10","key":"10.1016\/j.encep.2026.01.004_bib0525","doi-asserted-by":"crossref","first-page":"1026","DOI":"10.1002\/jclp.21970","article-title":"Efficacy of a cognitive-behavioral treatment for insomnia and nightmares in Afghanistan and Iraq veterans with PTSD","volume":"69","author":"Margolies","year":"2013","journal-title":"J Clin Psychol"},{"issue":"3","key":"10.1016\/j.encep.2026.01.004_bib0530","first-page":"47","article-title":"Accompagnement des troubles du sommeil chez les patients militaires souffrant d\u2019un trouble de stress post-traumatique","volume":"49","author":"Bernard","year":"2023","journal-title":"Med Armees"},{"key":"10.1016\/j.encep.2026.01.004_bib0535","series-title":"Psychomotor interventions for mental health\u00a0\u2013\u00a0adults: a movement- and body-oriented approach.","article-title":"Psychomotor interventions for mental health: an introduction","author":"Emck","year":"2019"},{"issue":"5","key":"10.1016\/j.encep.2026.01.004_bib0540","doi-asserted-by":"crossref","first-page":"835","DOI":"10.1002\/jts.22968","article-title":"Body- and movement-oriented interventions for posttraumatic stress disorder: an updated systematic review and meta-analysis","volume":"36","author":"Van de Kamp","year":"2023","journal-title":"J Trauma Stress"},{"issue":"3","key":"10.1016\/j.encep.2026.01.004_bib0545","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1089\/acm.2014.0407","article-title":"Yoga for adult women with chronic PTSD: a long-term follow-up study","volume":"22","author":"Rhodes","year":"2016","journal-title":"J Altern Complement Med"},{"key":"10.1016\/j.encep.2026.01.004_bib0550","unstructured":"American Psychological Association. Clinical practice guideline for the treatment of posttraumatic stress disorder (PTSD) in adults. https:\/\/www.apa.org\/about\/policy\/guideline-ptsd-in-adults.pdf. 2025 (accessed October 2025)."},{"key":"10.1016\/j.encep.2026.01.004_bib0555","unstructured":"Haute Autorit\u00e9 de sant\u00e9. Affections psychiatriques de longue dur\u00e9e\u00a0: troubles anxieux graves. https:\/\/www.has-sante.fr\/upload\/docs\/application\/pdf\/guide_medecin_troubles_anxieux.pdf. 2007 (accessed October 2025)."},{"key":"10.1016\/j.encep.2026.01.004_bib0560","unstructured":"U.S. Department of Veterans Affairs\/Department of Defense. Clinical practice guideline for the management of posttraumatic stress disorder and acute stress disorder. https:\/\/www.healthquality.va.gov\/guidelines\/MH\/ptsd\/2023 (accessed October 2025)."},{"key":"10.1016\/j.encep.2026.01.004_bib0565","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/j.brainres.2009.03.044","article-title":"Noradrenergic and serotonergic mechanisms in the neurobiology of posttraumatic stress disorder and resilience","volume":"1293","author":"Krystal","year":"2009","journal-title":"Brain Res"},{"issue":"4","key":"10.1016\/j.encep.2026.01.004_bib0570","doi-asserted-by":"crossref","first-page":"462","DOI":"10.1016\/j.encep.2021.12.008","article-title":"Pharmacog\u00e9n\u00e9tique des cytochromes appliqu\u00e9e \u00e0 la prescription des antid\u00e9presseurs: mode d\u2019emploi","volume":"48","author":"Baldacci","year":"2021","journal-title":"Enc\u00e9phale"},{"key":"10.1016\/j.encep.2026.01.004_bib0575","doi-asserted-by":"crossref","first-page":"1440523","DOI":"10.3389\/fphar.2024.1440523","article-title":"Pharmacogenetics testing for poor response to antidepressants: a transnosographic case series","volume":"15","author":"Lorvellec","year":"2024","journal-title":"Front Pharmacol"},{"issue":"5","key":"10.1016\/j.encep.2026.01.004_bib0580","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1001\/jama.2011.1080","article-title":"Adjunctive risperidone treatment for antidepressant-resistant symptoms of chronic military service-related PTSD: a randomized trial","volume":"306","author":"Krystal","year":"2011","journal-title":"JAMA"},{"key":"10.1016\/j.encep.2026.01.004_bib0585","series-title":"Troubles du sommeil et des rythmes biologiques associ\u00e9s aux troubles psychiatriques","article-title":"Troubles du sommeil li\u00e9s au stress post-traumatique","author":"Saguin","year":"2025"},{"issue":"4","key":"10.1016\/j.encep.2026.01.004_bib0590","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1055\/s-2001-15871","article-title":"Survey on the usefulness of trazodone in patients with PTSD with insomnia or nightmares","volume":"34","author":"Warner","year":"2001","journal-title":"Pharmacopsychiatry"},{"issue":"3","key":"10.1016\/j.encep.2026.01.004_bib0595","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/j.smrv.2007.09.003","article-title":"Sleep-specific mechanisms underlying posttraumatic stress disorder: integrative review and neurobiological hypotheses","volume":"12","author":"Germain","year":"2008","journal-title":"Sleep Med Rev"},{"issue":"5","key":"10.1016\/j.encep.2026.01.004_bib0600","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1037\/a0016570","article-title":"Overnight therapy? The role of sleep in emotional brain processing","volume":"135","author":"Walker","year":"2009","journal-title":"Psychol Bull"},{"issue":"2","key":"10.1016\/j.encep.2026.01.004_bib0605","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1176\/appi.ajp.160.2.371","article-title":"Reduction of nightmares and other PTSD symptoms in combat veterans by prazosin: a placebo-controlled study","volume":"160","author":"Raskind","year":"2003","journal-title":"Am J Psychiatry"},{"issue":"4","key":"10.1016\/j.encep.2026.01.004_bib0610","doi-asserted-by":"crossref","first-page":"494","DOI":"10.1080\/15299732.2016.1141150","article-title":"Meta-analysis of the efficacy and safety of prazosin versus placebo for the treatment of nightmares and sleep disturbances in adults with posttraumatic stress disorder","volume":"17","author":"George","year":"2016","journal-title":"J Trauma Dissociation"},{"issue":"6","key":"10.1016\/j.encep.2026.01.004_bib0615","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1056\/NEJMoa1507598","article-title":"Trial of prazosin for post-traumatic stress disorder in military veterans","volume":"378","author":"Raskind","year":"2018","journal-title":"N Engl J Med"},{"issue":"6","key":"10.1016\/j.encep.2026.01.004_bib0620","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1016\/j.biopsych.2007.07.001","article-title":"Prazosin effects on objective sleep measures and clinical symptoms in civilian trauma posttraumatic stress disorder: a placebo-controlled study","volume":"63","author":"Taylor","year":"2008","journal-title":"Biol Psychiatry"},{"issue":"4","key":"10.1016\/j.encep.2026.01.004_bib0625","article-title":"Efficacy of prazosin in posttraumatic stress disorder: a systematic review and meta-analysis","volume":"18","author":"Singh","year":"2016","journal-title":"Prim Care Companion CNS Disord"},{"key":"10.1016\/j.encep.2026.01.004_bib0630","unstructured":"Kassab M. Retrait du march\u00e9 de l\u2019Alpress LP\u00a0: point d\u2019information. https:\/\/www.pharma365.fr\/je-m-informe\/cote-medicament\/alpress-l-p-tire-sa-reverence-une-transition-therapeutique-a-anticiper\/2025 (accessed October 2025)."},{"key":"10.1016\/j.encep.2026.01.004_bib0635","unstructured":"Haute Autorit\u00e9 de sant\u00e9. ZOXAN LP (m\u00e9silate de doxazosine). https:\/\/www.has-sante.fr\/jcms\/p_3117823\/fr\/zoxan-lp-mesilate-de-doxazosine. 2019 (accessed October 2025)."},{"issue":"2","key":"10.1016\/j.encep.2026.01.004_bib0640","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1590\/1516-4446-2018-0292","article-title":"Treating nightmares in PTSD with doxazosin: a report of three cases","volume":"41","author":"Calegaro","year":"2019","journal-title":"Rev Bras Psiquiatr"},{"key":"10.1016\/j.encep.2026.01.004_bib0645","article-title":"Doxazosin for the treatment of nightmare disorder: a diary-based case study","volume":"8","author":"Pallesen","year":"2020","journal-title":"SAGE Open Med Case Rep"},{"issue":"5","key":"10.1016\/j.encep.2026.01.004_bib0650","article-title":"Doxazosin for the treatment of nightmares: does it really work? A case report","volume":"14","author":"Sethi","year":"2012","journal-title":"Prim Care Companion CNS Disord"},{"key":"10.1016\/j.encep.2026.01.004_bib0655","doi-asserted-by":"crossref","first-page":"S177","DOI":"10.1016\/j.jaclp.2022.10.134","article-title":"Less of a nightmare? A case report comparing doxazosin and prazosin for PTSD in the consultation-liaison setting","volume":"63","author":"Hessel","year":"2022","journal-title":"J Acad Consult Liaison Psychiatry"},{"key":"10.1016\/j.encep.2026.01.004_bib0660","doi-asserted-by":"crossref","first-page":"6452923","DOI":"10.1155\/crps\/6452923","article-title":"Doxazosin immediate release as a novel treatment for nightmares in posttraumatic stress disorder","volume":"2024","author":"Khan","year":"2024","journal-title":"Case Rep Psychiatry"},{"issue":"1","key":"10.1016\/j.encep.2026.01.004_bib0665","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1097\/JCP.0b013e3181c827ae","article-title":"Doxazosin treatment for posttraumatic stress disorder","volume":"30","author":"De Jong","year":"2010","journal-title":"J Clin Psychopharmacol"},{"issue":"5","key":"10.1016\/j.encep.2026.01.004_bib0670","doi-asserted-by":"crossref","first-page":"e561","DOI":"10.4088\/JCP.14m09681","article-title":"Doxazosin XL reduces symptoms of posttraumatic stress disorder in veterans with PTSD: a pilot clinical trial","volume":"77","author":"Rodgman","year":"2016","journal-title":"J Clin Psychiatry"},{"issue":"1","key":"10.1016\/j.encep.2026.01.004_bib0675","first-page":"26","article-title":"Doxazosin, an \u03b1-1-adrenergic-receptor antagonist, for nightmares in patients with posttraumatic stress disorder and\/or borderline personality disorder: a chart review","volume":"50","author":"Roepke","year":"2017","journal-title":"Pharmacopsychiatry"},{"issue":"2","key":"10.1016\/j.encep.2026.01.004_bib0680","doi-asserted-by":"crossref","DOI":"10.4088\/JCP.21m14367","article-title":"A double-blind randomized controlled trial of doxazosin for co-occurring PTSD and alcohol use disorder in veterans","volume":"84","author":"Back","year":"2023","journal-title":"J Clin Psychiatry"},{"key":"10.1016\/j.encep.2026.01.004_bib0685","doi-asserted-by":"crossref","first-page":"2165","DOI":"10.5664\/jcsm.11908","article-title":"A double-blind, randomized, placebo-controlled trial of doxazosin for posttraumatic distressing dreams and sleep disturbance in men and women with posttraumatic stress","volume":"21","author":"Richards","year":"2025","journal-title":"J Clin Sleep Med"},{"issue":"8","key":"10.1016\/j.encep.2026.01.004_bib0690","doi-asserted-by":"crossref","first-page":"e098161","DOI":"10.1136\/bmjopen-2024-098161","article-title":"Treating nightmares in post-traumatic stress disorder with the \u03b1-adrenergic agents clonidine and doxazosin: protocol for a phase II randomised, double-blind, placebo-controlled parallel-group study (ClonDoTrial)","volume":"15","author":"Roepke","year":"2025","journal-title":"BMJ Open"},{"key":"10.1016\/j.encep.2026.01.004_bib0695","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/j.smrv.2014.11.001","article-title":"Posttraumatic stress disorder and sleep-disordered breathing: a review of comorbidity research","volume":"24","author":"Kralow","year":"2015","journal-title":"Sleep Med Rev"},{"key":"10.1016\/j.encep.2026.01.004_bib0700","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/j.sleep.2017.04.020","article-title":"Prevalence of obstructive sleep apnea in patients with posttraumatic stress disorder and its impact on adherence to continuous positive airway pressure therapy: a meta-analysis","volume":"36","author":"Zhang","year":"2017","journal-title":"Sleep Med"},{"key":"10.1016\/j.encep.2026.01.004_bib0705","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1016\/j.neubiorev.2019.03.019","article-title":"The effect of treating obstructive sleep apnea with continuous positive airway pressure on posttraumatic stress disorder: a systematic review and meta-analysis with hypothetical model","volume":"102","author":"Zhang","year":"2019","journal-title":"Neurosci Biobehav Rev"},{"issue":"2","key":"10.1016\/j.encep.2026.01.004_bib0710","doi-asserted-by":"crossref","first-page":"415","DOI":"10.3390\/jcm11020415","article-title":"A narrative review of the association between post-traumatic stress disorder and obstructive sleep apnea","volume":"11","author":"McCall","year":"2022","journal-title":"J Clin Med"}],"container-title":["L'Enc\u00e9phale"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0013700626000333?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0013700626000333?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,8,2]],"date-time":"2026-08-02T19:28:38Z","timestamp":1785698918000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0013700626000333"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8]]},"references-count":71,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2026,8]]}},"alternative-id":["S0013700626000333"],"URL":"https:\/\/doi.org\/10.1016\/j.encep.2026.01.004","relation":{},"ISSN":["0013-7006"],"issn-type":[{"value":"0013-7006","type":"print"}],"subject":[],"published":{"date-parts":[[2026,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Management of trauma-related nightmares in PTSD: Can doxazosin serve as a pragmatic alternative to prazosin?","name":"articletitle","label":"Article Title"},{"value":"L'Enc\u00e9phale","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.encep.2026.01.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 L'Enc\u00e9phale, Paris.","name":"copyright","label":"Copyright"}]}}