{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T16:08:43Z","timestamp":1787501323828,"version":"build-2736575974"},"reference-count":56,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T00:00:00Z","timestamp":1781568000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["L'Enc\u00e9phale"],"published-print":{"date-parts":[[2026,7]]},"DOI":"10.1016\/j.encep.2026.03.022","type":"journal-article","created":{"date-parts":[[2026,7,27]],"date-time":"2026-07-27T19:34:25Z","timestamp":1785180865000},"update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"title":["Cognitive flexibility and depression remission: A narrative review"],"prefix":"10.1016","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-6664-4669","authenticated-orcid":false,"given":"Candice","family":"Roberge","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-3975-8402","authenticated-orcid":false,"given":"Lisa","family":"Borgmann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4522-2857","authenticated-orcid":false,"given":"Jean-Marie","family":"Batail","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.encep.2026.03.022_bib0005","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1186\/s12888-024-05675-6","article-title":"Relationship between cognitive function and functional outcomes in remitted major depression","volume":"24","author":"Luo","year":"2024","journal-title":"BMC Psychiatry"},{"issue":"3","key":"10.1016\/j.encep.2026.03.022_bib0010","doi-asserted-by":"crossref","first-page":"e0230363","DOI":"10.1371\/journal.pone.0230363","article-title":"Predictors of recurrence of major depressive disorder","volume":"15","author":"Lye","year":"2020","journal-title":"PLoS One"},{"issue":"7","key":"10.1016\/j.encep.2026.03.022_bib0015","doi-asserted-by":"crossref","first-page":"e063095","DOI":"10.1136\/bmjopen-2022-063095","volume":"13","author":"Pigott","year":"2023","journal-title":"BMJ Open"},{"key":"10.1016\/j.encep.2026.03.022_bib0020","doi-asserted-by":"crossref","first-page":"468","DOI":"10.1038\/s41398-022-02240-1","article-title":"Evaluating cognitive disturbances as treatment target and predictor of antidepressant action in major depressive disorder: a NeuroPharm study","volume":"12","author":"Dam","year":"2022","journal-title":"Transl Psychiatry"},{"issue":"13","key":"10.1016\/j.encep.2026.03.022_bib0025","doi-asserted-by":"crossref","first-page":"6334","DOI":"10.1017\/S0033291722003671","article-title":"The association between persistent cognitive difficulties and depression and functional outcomes in people with major depressive disorder","volume":"53","author":"Matcham","year":"2023","journal-title":"Psychol Med"},{"key":"10.1016\/j.encep.2026.03.022_bib0030","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/j.bbr.2019.04.002","article-title":"The neural systems of emotion regulation and abnormalities in major depressive disorder","volume":"367","author":"Park","year":"2019","journal-title":"Behav Brain Res"},{"key":"10.1016\/j.encep.2026.03.022_bib0035","doi-asserted-by":"crossref","first-page":"101484","DOI":"10.1016\/j.cobeha.2025.101484","article-title":"Neurostimulation to improve cognitive flexibility","volume":"62","author":"Sachse","year":"2025","journal-title":"Curr Opin Behav Sci"},{"issue":"9","key":"10.1016\/j.encep.2026.03.022_bib0040","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1016\/j.tins.2015.07.003","article-title":"Demystifying cognitive flexibility: Implications for clinical and developmental neuroscience","volume":"38","author":"Dajani","year":"2015","journal-title":"Trends Neurosci"},{"key":"10.1016\/j.encep.2026.03.022_bib0045","doi-asserted-by":"crossref","first-page":"85","DOI":"10.3389\/fnbeh.2017.00085","article-title":"Trait rumination influences neural correlates of the anticipation but not the consumption phase of reward processing","volume":"11","author":"Kocsel","year":"2017","journal-title":"Front Behav Neurosci"},{"issue":"3","key":"10.1016\/j.encep.2026.03.022_bib0050","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1038\/s41583-021-00428-w","article-title":"Cognitive and behavioural flexibility: neural mechanisms and clinical considerations","volume":"22","author":"Uddin","year":"2021","journal-title":"Nat Rev Neurosci"},{"issue":"12","key":"10.1016\/j.encep.2026.03.022_bib0055","doi-asserted-by":"crossref","first-page":"1000","DOI":"10.3390\/brainsci10121000","article-title":"Toward a computational neuropsychology of cognitive flexibility","volume":"10","author":"Steinke","year":"2020","journal-title":"Brain Sci"},{"issue":"3","key":"10.1016\/j.encep.2026.03.022_bib0060","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1089\/brain.2015.0388","article-title":"Cognitive flexibility: a default network and basal ganglia connectivity perspective","volume":"6","author":"Vatansever","year":"2016","journal-title":"Brain Connect"},{"issue":"2","key":"10.1016\/j.encep.2026.03.022_bib0065","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1016\/j.biopsych.2020.05.010","article-title":"Brain mechanisms supporting flexible cognition and behavior in adolescents with autism spectrum disorder","volume":"89","author":"Uddin","year":"2021","journal-title":"Biol Psychiatry"},{"issue":"1","key":"10.1016\/j.encep.2026.03.022_bib0070","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1017\/S1092852918001402","article-title":"Circuit based anti-correlation, attention orienting, and major depression","volume":"24","author":"Fossati","year":"2019","journal-title":"CNS Spectr"},{"key":"10.1016\/j.encep.2026.03.022_bib0075","doi-asserted-by":"crossref","first-page":"485","DOI":"10.3389\/fpsyt.2020.00485","article-title":"The link between structural and functional brain abnormalities in depression: a systematic review of multimodal neuroimaging studies","volume":"11","author":"Scheepens","year":"2020","journal-title":"Front Psychiatry"},{"key":"10.1016\/j.encep.2026.03.022_bib0080","doi-asserted-by":"crossref","first-page":"1331960","DOI":"10.3389\/fnhum.2024.1331960","article-title":"Measuring cognitive flexibility: a brief review of neuropsychological, self-report, and neuroscientific approaches","volume":"18","author":"Hohl","year":"2024","journal-title":"Front Hum Neurosci"},{"issue":"2","key":"10.1016\/j.encep.2026.03.022_bib0085","first-page":"106","article-title":"Dissociation between spontaneous and reactive flexibility in early Parkinson's disease","volume":"15","author":"Tomer","year":"2002","journal-title":"Neuropsychiatry Neuropsychol Behav Neurol"},{"issue":"8","key":"10.1016\/j.encep.2026.03.022_bib0090","doi-asserted-by":"crossref","first-page":"1749","DOI":"10.1007\/s00426-018-1034-3","article-title":"Cognitive flexibility and religious disbelief","volume":"83","author":"Zmigrod","year":"2019","journal-title":"Psychol Res"},{"issue":"1","key":"10.1016\/j.encep.2026.03.022_bib0095","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1080\/138033990513654","article-title":"A meta-analytic review of verbal fluency deficits in depression","volume":"27","author":"Henry","year":"2005","journal-title":"J Clin Exp Neuropsychol"},{"issue":"2","key":"10.1016\/j.encep.2026.03.022_bib0100","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/S0165-1781(01)00307-9","article-title":"Problem-solving abilities in unipolar depressed patients: comparison of performance on the modified version of the Wisconsin and the California sorting tests","volume":"104","author":"Fossati","year":"2001","journal-title":"Psychiatry Res"},{"issue":"11","key":"10.1016\/j.encep.2026.03.022_bib0105","doi-asserted-by":"crossref","first-page":"5263","DOI":"10.1093\/cercor\/bhab156","article-title":"Brain dynamics underlying cognitive flexibility across the lifespan","volume":"31","author":"Kupis","year":"2021","journal-title":"Cereb Cortex"},{"issue":"1","key":"10.1016\/j.encep.2026.03.022_bib0110","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1038\/s41386-021-01152-w","article-title":"The role of PFC networks in cognitive control and executive function","volume":"47","author":"Menon","year":"2022","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.encep.2026.03.022_bib0115","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1016\/j.neuroscience.2016.09.034","article-title":"State-dependent variability of dynamic functional connectivity between frontoparietal and default networks relates to cognitive flexibility","volume":"339","author":"Douw","year":"2016","journal-title":"Neuroscience"},{"issue":"7","key":"10.1016\/j.encep.2026.03.022_bib0120","doi-asserted-by":"crossref","first-page":"1537","DOI":"10.1038\/s41380-019-0574-2","article-title":"Intrinsic connectomes are a predictive biomarker of remission in major depressive disorder","volume":"25","author":"Korgaonkar","year":"2020","journal-title":"Mol Psychiatry"},{"issue":"3","key":"10.1016\/j.encep.2026.03.022_bib0125","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1016\/j.neuron.2008.04.017","article-title":"The reorienting system of the human brain: from environment to theory of mind","volume":"58","author":"Corbetta","year":"2008","journal-title":"Neuron"},{"key":"10.1016\/j.encep.2026.03.022_bib0130","doi-asserted-by":"crossref","first-page":"1250096","DOI":"10.3389\/fnhum.2023.1250096","article-title":"Neuroimaging evidence supporting a dual-network architecture for the control of visuospatial attention in the human brain: a mini review","volume":"17","author":"Tosoni","year":"2023","journal-title":"Front Hum Neurosci"},{"issue":"16","key":"10.1016\/j.encep.2026.03.022_bib0135","doi-asserted-by":"crossref","first-page":"2469","DOI":"10.1016\/j.neuron.2023.04.023","article-title":"20 years of the default mode network: a review and synthesis","volume":"111","author":"Menon","year":"2023","journal-title":"Neuron"},{"issue":"10","key":"10.1016\/j.encep.2026.03.022_bib0140","doi-asserted-by":"crossref","first-page":"872","DOI":"10.1016\/j.biopsych.2018.12.007","article-title":"Pre-treatment rostral anterior cingulate cortex connectivity with salience network predicts depression recovery: findings from the EMBARC randomized clinical trial","volume":"85","author":"Whitton","year":"2019","journal-title":"Biol Psychiatry"},{"issue":"12","key":"10.1016\/j.encep.2026.03.022_bib0145","doi-asserted-by":"crossref","first-page":"e3002937","DOI":"10.1371\/journal.pbio.3002937","article-title":"The thalamus encodes and updates context representations during hierarchical cognitive control","volume":"22","author":"Chen","year":"2024","journal-title":"PLoS Biol"},{"key":"10.1016\/j.encep.2026.03.022_bib0150","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/j.neuropsychologia.2013.11.015","article-title":"Cognitive flexibility depends on white matter microstructure of the basal ganglia","volume":"53","author":"van Schouwenburg","year":"2014","journal-title":"Neuropsychologia"},{"issue":"12","key":"10.1016\/j.encep.2026.03.022_bib0155","doi-asserted-by":"crossref","first-page":"1316","DOI":"10.1016\/j.jagp.2019.07.016","article-title":"Disruption of neural homeostasis as a model of relapse and recurrence in late-life depression","volume":"27","author":"Andreescu","year":"2019","journal-title":"Am J Geriatr Psychiatry"},{"issue":"4","key":"10.1016\/j.encep.2026.03.022_bib0160","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1089\/brain.2023.0063","article-title":"Structural brain connectivity and treatment improvement in mood disorder","volume":"14","author":"Dam","year":"2024","journal-title":"Brain Connect"},{"issue":"1","key":"10.1016\/j.encep.2026.03.022_bib0165","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1196\/annals.1440.011","article-title":"The brain's default network","volume":"1124","author":"Buckner","year":"2008","journal-title":"Ann N Y Acad Sci"},{"key":"10.1016\/j.encep.2026.03.022_bib0170","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1146\/annurev-clinpsy-081219-115627","article-title":"Allostasis, action, and affect in depression: insights from the theory of constructed emotion","volume":"18","author":"Shaffer","year":"2022","journal-title":"Annu Rev Clin Psychol"},{"key":"10.1016\/j.encep.2026.03.022_bib0175","doi-asserted-by":"crossref","first-page":"111158","DOI":"10.1016\/j.pscychresns.2020.111158","article-title":"Structural abnormalities associated with poor outcome of a major depressive episode: the role of thalamus","volume":"305","author":"Batail","year":"2020","journal-title":"Psychiatry Res Neuroimaging"},{"issue":"4","key":"10.1016\/j.encep.2026.03.022_bib0180","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1017\/S0033291711001668","article-title":"Meta-analysis of volumetric abnormalities in cortico-striatal-pallidal-thalamic circuits in major depressive disorder","volume":"42","author":"Bora","year":"2012","journal-title":"Psychol Med"},{"key":"10.1016\/j.encep.2026.03.022_bib0185","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1016\/j.nbd.2012.01.015","article-title":"Neural systems approaches to understanding major depressive disorder: an intrinsic functional organization perspective","volume":"52C","author":"Hamilton","year":"2013","journal-title":"Neurobiol Dis"},{"issue":"7","key":"10.1016\/j.encep.2026.03.022_bib0190","doi-asserted-by":"crossref","first-page":"1822","DOI":"10.1038\/npp.2015.352","article-title":"Dynamic resting-state functional connectivity in major depression","volume":"41","author":"Kaiser","year":"2016","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.encep.2026.03.022_bib0195","doi-asserted-by":"crossref","first-page":"101710","DOI":"10.1016\/j.nicl.2019.101710","article-title":"White matter abnormalities in depression: a categorical and phenotypic diffusion MRI study","volume":"22","author":"Coloigner","year":"2019","journal-title":"Neuroimage Clin"},{"issue":"11","key":"10.1016\/j.encep.2026.03.022_bib0200","doi-asserted-by":"crossref","first-page":"1005","DOI":"10.1002\/da.22513","article-title":"Inflexible cognition predicts first onset of major depressive episodes in adolescence","volume":"33","author":"Stange","year":"2016","journal-title":"Depress Anxiety"},{"key":"10.1016\/j.encep.2026.03.022_bib0205","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3389\/fncir.2024.1283372","article-title":"I like therefore I can, and I can therefore I like: the role of self-efficacy and affect in active inference of allostasis","volume":"18","author":"Krupnik","year":"2024","journal-title":"Front Neural Circuits"},{"key":"10.1016\/j.encep.2026.03.022_bib0210","first-page":"100729","article-title":"State rumination predicts inhibitory control failures and dysregulation of default, salience, and cognitive control networks in youth at risk of depressive relapse: findings from the RuMeChange trial","volume":"16","author":"Roberts","year":"2024","journal-title":"J Affect Disord Rep"},{"issue":"3","key":"10.1016\/j.encep.2026.03.022_bib0215","doi-asserted-by":"crossref","first-page":"858","DOI":"10.1007\/s00426-021-01537-y","article-title":"Response inhibition deficits are positively associated with trait rumination, but attentional inhibition deficits are not: aggressive behaviors and interpersonal stressors as mediators","volume":"86","author":"Hasegawa","year":"2022","journal-title":"Psychol Res"},{"issue":"5","key":"10.1016\/j.encep.2026.03.022_bib0220","doi-asserted-by":"crossref","first-page":"1452","DOI":"10.3758\/s13414-022-02649-2","article-title":"Rumination burdens the updating of working memory","volume":"85","author":"Bruning","year":"2023","journal-title":"Atten Percept Psychophys"},{"issue":"10","key":"10.1016\/j.encep.2026.03.022_bib0225","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1016\/j.tics.2011.08.003","article-title":"Large-scale brain networks and psychopathology: a unifying triple network model","volume":"15","author":"Menon","year":"2011","journal-title":"Trends Cogn Sci"},{"issue":"8","key":"10.1016\/j.encep.2026.03.022_bib0230","doi-asserted-by":"crossref","first-page":"2918","DOI":"10.1002\/hbm.23215","article-title":"Dynamic functional connectivity reveals altered variability in functional connectivity among patients with major depressive disorder","volume":"37","author":"Demirta\u015f","year":"2016","journal-title":"Hum Brain Mapp"},{"key":"10.1016\/j.encep.2026.03.022_bib0235","doi-asserted-by":"crossref","first-page":"111076","DOI":"10.1016\/j.pnpbp.2024.111076","article-title":"Resting-state dynamic functional connectivity in major depressive disorder: a systematic review","volume":"135","author":"Sun","year":"2024","journal-title":"Prog Neuropsychopharmacol Biol Psychiatry"},{"key":"10.1016\/j.encep.2026.03.022_bib0240","doi-asserted-by":"crossref","first-page":"113999","DOI":"10.1016\/j.bbr.2022.113999","article-title":"Resting-state neural signal variability in women with depressive disorders","volume":"433","author":"Pessin","year":"2022","journal-title":"Behav Brain Res"},{"issue":"4","key":"10.1016\/j.encep.2026.03.022_bib0245","doi-asserted-by":"crossref","first-page":"600","DOI":"10.1002\/erv.2829","article-title":"Increased cognitive flexibility mediates the improvement of eating disorders symptoms, depressive symptoms and level of daily life functioning in patients with anorexia nervosa treated in specialised centres","volume":"29","author":"Duriez","year":"2021","journal-title":"Eur Eat Disord Rev"},{"key":"10.1016\/j.encep.2026.03.022_bib0250","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3389\/fpsyg.2018.02219","article-title":"Cognitive control and flexibility in the context of stress and depressive symptoms: the Cognitive Control and Flexibility Questionnaire","volume":"9","author":"Gabrys","year":"2018","journal-title":"Front Psychol"},{"issue":"1","key":"10.1016\/j.encep.2026.03.022_bib0255","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1037\/emo0001410","article-title":"Situation covariation and goal adaptiveness? The promoting effect of cognitive flexibility on emotion regulation in depression","volume":"25","author":"Gao","year":"2025","journal-title":"Emotion"},{"key":"10.1016\/j.encep.2026.03.022_bib0260","doi-asserted-by":"crossref","first-page":"382","DOI":"10.3389\/fpsyt.2018.00382","article-title":"A systematic review of cognitive predictors of treatment outcome in major depression","volume":"9","author":"Groves","year":"2018","journal-title":"Front Psychiatry"},{"key":"10.1016\/j.encep.2026.03.022_bib0265","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1186\/s12916-016-0560-3","article-title":"Cognitive remission: a novel objective for the treatment of major depression?","volume":"14","author":"Bortolato","year":"2016","journal-title":"BMC Med"},{"key":"10.1016\/j.encep.2026.03.022_bib0270","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/j.ibneur.2023.12.011","article-title":"Assessing remission in major depressive disorder using a functional-structural data fusion pipeline: a CAN-BIND-1 study","volume":"16","author":"Ayyash","year":"2024","journal-title":"IBRO Neurosci Rep"},{"issue":"4","key":"10.1016\/j.encep.2026.03.022_bib0275","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1016\/j.biopsych.2011.03.009","article-title":"Mood linked responses in medial prefrontal cortex predict relapse in patients with recurrent unipolar depression","volume":"70","author":"Farb","year":"2011","journal-title":"Biol Psychiatry"},{"key":"10.1016\/j.encep.2026.03.022_bib0280","doi-asserted-by":"crossref","first-page":"666","DOI":"10.3389\/fnhum.2013.00666","article-title":"Self-Referential processing, rumination, and cortical midline structures in major depression","volume":"7","author":"Nejad","year":"2013","journal-title":"Front Hum Neurosci"}],"container-title":["L'Enc\u00e9phale"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0013700626001272?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0013700626001272?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,7,27]],"date-time":"2026-07-27T19:34:32Z","timestamp":1785180872000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0013700626001272"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7]]},"references-count":56,"alternative-id":["S0013700626001272"],"URL":"https:\/\/doi.org\/10.1016\/j.encep.2026.03.022","relation":{},"ISSN":["0013-7006"],"issn-type":[{"value":"0013-7006","type":"print"}],"subject":[],"published":{"date-parts":[[2026,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Cognitive flexibility and depression remission: A narrative review","name":"articletitle","label":"Article Title"},{"value":"L'Enc\u00e9phale","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.encep.2026.03.022","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 L'Enc\u00e9phale, Paris.","name":"copyright","label":"Copyright"}]}}