{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,11]],"date-time":"2025-11-11T13:27:51Z","timestamp":1762867671724,"version":"build-2065373602"},"reference-count":55,"publisher":"Elsevier BV","issue":"7","license":[{"start":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T00:00:00Z","timestamp":1659312000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T00:00:00Z","timestamp":1659312000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Endocrinolog\u00eda, Diabetes y Nutrici\u00f3n (English ed.)"],"published-print":{"date-parts":[[2022,8]]},"DOI":"10.1016\/j.endien.2022.08.002","type":"journal-article","created":{"date-parts":[[2022,8,23]],"date-time":"2022-08-23T07:36:14Z","timestamp":1661240174000},"page":"530-539","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Guide of management of alterations in mineral and bone metabolism during gestation and lactation"],"prefix":"10.1016","volume":"69","author":[{"given":"Antonia","family":"Garc\u00eda Mart\u00edn","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mar\u00eda Rosa","family":"Alhambra Exp\u00f3sito","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mar\u00eda","family":"Cort\u00e9s Berdonces","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Esteban","family":"J\u00f3dar Gimeno","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Isabel","family":"Huguet","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pedro","family":"Rozas Moreno","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mariela","family":"Varsavsky","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ver\u00f3nica","family":"\u00c1vila Rubio","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Araceli","family":"Mu\u00f1oz Garach","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manuel","family":"Mu\u00f1oz Torres","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.endien.2022.08.002_bib0005","doi-asserted-by":"crossref","first-page":"1490","DOI":"10.1136\/bmj.328.7454.1490","article-title":"Grading quality of evidence and strength of recommendations","volume":"328","author":"Atkins","year":"2004","journal-title":"BMJ"},{"key":"10.1016\/j.endien.2022.08.002_bib0010","series-title":"Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism","first-page":"147","article-title":"Pregnancy and lactation","author":"Kovacs","year":"2019"},{"key":"10.1016\/j.endien.2022.08.002_bib0015","doi-asserted-by":"crossref","first-page":"468","DOI":"10.1097\/MED.0000000000000102","article-title":"Osteoporosis presenting in pregnancy, puerperium, and lactation","volume":"21","author":"Kovacs","year":"2014","journal-title":"Curr Opin Endocrinol Diabetes Obes"},{"key":"10.1016\/j.endien.2022.08.002_bib0020","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1042\/cs0940405","article-title":"Bone mineral changes during pregnancy and lactation: a longitudinal cohort study","volume":"94","author":"Kolthoff","year":"1998","journal-title":"Clin Sci"},{"key":"10.1016\/j.endien.2022.08.002_bib0025","doi-asserted-by":"crossref","first-page":"3575","DOI":"10.1007\/s10067-019-04758-0","article-title":"Long-term outcome of patients with pregnancy and lactation-associated osteoporosis (PLO) with a particular focus on quality of life","volume":"38","author":"Gehlen","year":"2019","journal-title":"Clin Rheumatol"},{"key":"10.1016\/j.endien.2022.08.002_bib0030","doi-asserted-by":"crossref","first-page":"1643","DOI":"10.1007\/s00198-018-4499-4","article-title":"Mutational analysis uncovers monogenic bone disorders in women with pregnancy-associated osteoporosis: three novel mutations in LRP5, COL1A1, and COL1A2","volume":"29","author":"Butscheidt","year":"2018","journal-title":"Osteoporos Int"},{"key":"10.1016\/j.endien.2022.08.002_bib0035","doi-asserted-by":"crossref","first-page":"410","DOI":"10.1097\/BOR.0000000000000400","article-title":"Osteoporosis in premenopausal women","volume":"29","author":"Langdahl","year":"2017","journal-title":"Curr Opin Rheumatol"},{"key":"10.1016\/j.endien.2022.08.002_bib0040","doi-asserted-by":"crossref","first-page":"1552","DOI":"10.1002\/jbmr.3750","article-title":"Women with pregnancy and lactation\u2013associated osteoporosis (PLO) have low bone remodeling rates at the tissue level","volume":"34","author":"Cohen","year":"2019","journal-title":"J Bone Miner Res"},{"key":"10.1016\/j.endien.2022.08.002_bib0045","doi-asserted-by":"crossref","first-page":"3135","DOI":"10.1007\/s00198-017-4165-2","article-title":"Pregnancy-related fractures: a retrospective study of a French cohort of 52 patients and review of the literature","volume":"28","author":"Laroche","year":"2017","journal-title":"Osteoporos Int"},{"key":"10.1016\/j.endien.2022.08.002_bib0050","doi-asserted-by":"crossref","first-page":"R53","DOI":"10.1530\/EJE-14-0424","article-title":"Bone metabolic changes during pregnancy: a period of vulnerability to osteoporosis and fracture","volume":"172","author":"Sanz-Salvador","year":"2015","journal-title":"Eur J Endocrinol"},{"key":"10.1016\/j.endien.2022.08.002_bib0055","doi-asserted-by":"crossref","first-page":"1067","DOI":"10.1111\/jog.13313","article-title":"Bilateral femoral neck fractures resulting from pregnancy-associated osteoporosis showed bone marrow edema on magnetic resonance imaging","volume":"43","author":"Kasahara","year":"2017","journal-title":"J Obstet Gynaecol Res"},{"key":"10.1016\/j.endien.2022.08.002_bib0060","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1080\/01443615.2017.1352571","article-title":"Bilateral transient osteoporosis of the hip in pregnancy","volume":"38","author":"Thanatsis","year":"2018","journal-title":"J Obstet Gynaecol"},{"key":"10.1016\/j.endien.2022.08.002_bib0065","doi-asserted-by":"crossref","first-page":"3141","DOI":"10.1007\/s10067-018-4185-0","article-title":"Clinical characteristics and bisphosphonates treatment of rare pregnancy- and lactation-associated osteoporosis","volume":"37","author":"Li","year":"2018","journal-title":"Clin Rheumatol"},{"key":"10.1016\/j.endien.2022.08.002_bib0070","doi-asserted-by":"crossref","first-page":"939","DOI":"10.1007\/s00198-019-04842-w","article-title":"Pregnancy-associated osteoporosis: a UK case series and literature review","volume":"30","author":"Hardcastle","year":"2019","journal-title":"Osteoporos Int"},{"key":"10.1016\/j.endien.2022.08.002_bib0075","doi-asserted-by":"crossref","first-page":"596","DOI":"10.1007\/s00774-011-0334-0","article-title":"Effect of teriparatide on pregnancy and lactation-associated osteoporosis with multiple vertebral fractures","volume":"30","author":"Choe","year":"2012","journal-title":"J Bone Miner Metab"},{"key":"10.1016\/j.endien.2022.08.002_bib0080","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1007\/s12018-019-09262-2","article-title":"Comparison of efficacy of pharmacologic treatments in pregnancy- and lactation-associated osteoporosis","volume":"17","author":"Hong","year":"2019","journal-title":"Clin Rev Bone Miner Metab"},{"key":"10.1016\/j.endien.2022.08.002_bib0085","doi-asserted-by":"crossref","first-page":"267","DOI":"10.2147\/IJWH.S198345","article-title":"Femoral fracture in pregnancy: a case series and review of clinical management","volume":"11","author":"Harold","year":"2019","journal-title":"Int J Womens Health"},{"key":"10.1016\/j.endien.2022.08.002_bib0090","doi-asserted-by":"crossref","first-page":"2241","DOI":"10.3390\/ijerph15102241","article-title":"The role of vitamin D in fertility and during pregnancy and lactation: a review of clinical data","volume":"15","author":"Pilz","year":"2018","journal-title":"Int J Environ Res Public Health"},{"key":"10.1016\/j.endien.2022.08.002_bib0095","first-page":"1633","article-title":"Prevalence of vitamin d deficiency and insuffiency and associated factors in pregnant women of northern Spain","volume":"31","author":"Rodr\u00edguez-Dehli","year":"2015","journal-title":"Nutr Hosp"},{"key":"10.1016\/j.endien.2022.08.002_bib0100","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1111\/ppe.12281","article-title":"Vitamin D status in pregnancy and determinants in a Southern European Cohort Study","volume":"30","author":"Rodriguez","year":"2016","journal-title":"Paediatr Perinat Epidemiol"},{"key":"10.1016\/j.endien.2022.08.002_bib0105","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1038\/s41430-018-0373-x","article-title":"Vitamin D status during pregnancy and offspring outcomes: a systematic review and meta-analysis of observational studies","volume":"74","author":"Tous","year":"2020","journal-title":"Eur J Clin Nutr"},{"key":"10.1016\/j.endien.2022.08.002_bib0110","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1016\/j.tjog.2018.02.013","article-title":"Association of vitamin D level and vitamin D deficiency with risk of preeclampsia: a systematic review and updated meta-analysis","volume":"57","author":"Akbari","year":"2018","journal-title":"Taiwan J Obstet Gynecol"},{"key":"10.1016\/j.endien.2022.08.002_bib0115","doi-asserted-by":"crossref","first-page":"7","DOI":"10.3389\/fendo.2018.00007","article-title":"Effects of vitamin D deficiency on incidence risk of gestational diabetes mellitus: a systematic review and meta-analysis","volume":"9","author":"Amraei","year":"2018","journal-title":"Front Endocrinol (Lausanne)"},{"key":"10.1016\/j.endien.2022.08.002_bib0120","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0173605","article-title":"Maternal vitamin D insufficiency and risk of adverse pregnancy and birth outcomes: a systematic review and meta-analysis of longitudinal studies","volume":"12","author":"Amegah","year":"2017","journal-title":"PLoS One"},{"key":"10.1016\/j.endien.2022.08.002_bib0125","doi-asserted-by":"crossref","first-page":"1820","DOI":"10.1080\/14767058.2017.1419176","article-title":"Vitamin D status in pregnant women with asthma and its association with adverse respiratory outcomes during infancy","volume":"32","author":"Jensen","year":"2019","journal-title":"J Matern Fetal Neonatal Med"},{"issue":"7","key":"10.1016\/j.endien.2022.08.002_bib0130","article-title":"Vitamin D supplementation for women during pregnancy","volume":"7","author":"Palacios","year":"2019","journal-title":"Cochrane Database Syst Rev"},{"issue":"10","key":"10.1016\/j.endien.2022.08.002_bib0135","article-title":"Regimens of vitamin D supplementation for women during pregnancy","volume":"10","author":"Palacios","year":"2019","journal-title":"Cochrane Database Syst Rev"},{"key":"10.1016\/j.endien.2022.08.002_bib0140","article-title":"Vitamin D supplementation during pregnancy: state of the evidence from a systematic review of randomised trials","volume":"359","author":"Roth","year":"2017","journal-title":"BMJ"},{"key":"10.1016\/j.endien.2022.08.002_bib0145","series-title":"2011 Dietary reference intakes for calcium and vitamin D","first-page":"260","author":"IOM (Institute of Medicine)","year":"2011"},{"key":"10.1016\/j.endien.2022.08.002_bib0150","doi-asserted-by":"crossref","first-page":"1153","DOI":"10.1210\/jc.2011-2601","article-title":"Guidelines for preventing and treating vitamin D deficiency and insufficiency revisited","volume":"97","author":"Holick","year":"2012","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.endien.2022.08.002_bib0155","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/j.endinu.2016.11.002","article-title":"Recommended vitamin D levels in the general population","volume":"64 Supl. 1","author":"Varsavsky","year":"2017","journal-title":"Endocrinol Diabetes Nutr"},{"key":"10.1016\/j.endien.2022.08.002_bib0160","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1001\/jamapediatrics.2018.0302","article-title":"Association between vitamin D supplementation during pregnancy and offspring growth, morbidity, and mortality: a systematic review and meta-analysis","volume":"172","author":"Bi","year":"2018","journal-title":"JAMA Pediatr"},{"key":"10.1016\/j.endien.2022.08.002_bib0165","doi-asserted-by":"crossref","first-page":"721","DOI":"10.1210\/jc.2018-01104","article-title":"Primary hyperparathyroidism in pregnancy: maternofetal outcomes at a quaternary referral obstetric hospital, 2000 through 2015","volume":"104","author":"Rigg","year":"2019","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.endien.2022.08.002_bib0170","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1016\/j.ecl.2019.05.007","article-title":"Calcium metabolic disorders in pregnancy, primary hyperparathyroidism, pregnancy-induced osteoporosis, and vitamin D deficiency in pregnancy","volume":"48","author":"Leere","year":"2019","journal-title":"Endocrinol Metab Clin D Am"},{"key":"10.1016\/j.endien.2022.08.002_bib0175","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1111\/j.1365-2265.2008.03495.x","article-title":"Hyperparathyroidism during pregnancy and the effect of risin calcium on pregnancy los: a call for earlier intervention","volume":"71","author":"Norman","year":"2009","journal-title":"Clin Endocrinol (Oxf)"},{"key":"10.1016\/j.endien.2022.08.002_bib0180","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1007\/s12020-013-9980-4","article-title":"Primary hyperparathyroidism in pregnancy","volume":"44","author":"Diaz-Soto","year":"2013","journal-title":"Endocrine"},{"key":"10.1016\/j.endien.2022.08.002_bib0185","first-page":"1","article-title":"Contemporary medical manegement of primary hyperparathyroidism: a systematic review","volume":"8","author":"Leere","year":"2017","journal-title":"Front Endocrinol (Lausanne)"},{"key":"10.1016\/j.endien.2022.08.002_bib0190","doi-asserted-by":"crossref","first-page":"1093","DOI":"10.1530\/EJE-12-0032","article-title":"Renal stones and calficications in patients with primary hyperparthyroidism associations with biochemical variable","volume":"166","author":"Starup- Linde","year":"2012","journal-title":"Eur J Endocrinol"},{"key":"10.1016\/j.endien.2022.08.002_bib0195","doi-asserted-by":"crossref","DOI":"10.1155\/2018\/2091082","article-title":"Preterm parturent with polyhidramnios and pancreatitis primary presentation of hyperparthyroidism","author":"Han","year":"2018","journal-title":"Case Rep Obstet Gynecol"},{"key":"10.1016\/j.endien.2022.08.002_bib0200","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1177\/1753495X18799569","article-title":"Hypercalcemia during pregnancy: review of maternal and fetal complications, investigations, and management","volume":"12","author":"Gehlert","year":"2019","journal-title":"Obstetric Med"},{"key":"10.1016\/j.endien.2022.08.002_bib0205","doi-asserted-by":"crossref","first-page":"1156","DOI":"10.1210\/js.2017-00308","article-title":"Use of cinacalcet and 99mc Tc-sestamibi imaging during pregnancy","volume":"1","author":"Rubin","year":"2017","journal-title":"J Endocr Soc"},{"key":"10.1016\/j.endien.2022.08.002_bib0210","doi-asserted-by":"crossref","first-page":"R37","DOI":"10.1530\/EJE-18-0541","article-title":"Hypoparathyroidism in pregnancy: review and evidence-based recommendations for management","volume":"180","author":"Khan","year":"2019","journal-title":"Eur J Endocrinol"},{"key":"10.1016\/j.endien.2022.08.002_bib0215","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1111\/cen.14212","article-title":"Changes in treatment needs of hypoparathyroidism during pregnancy and lactation: a case series","volume":"93","author":"Hartogsohn","year":"2020","journal-title":"Clin Endocrinol (Oxf)"},{"key":"10.1016\/j.endien.2022.08.002_bib0220","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1007\/BF03345501","article-title":"Post-partum hypocalcemia: idiopatic hypoparathyroidism manifested early in lactation","volume":"25","author":"Durst","year":"2002","journal-title":"J Endocrinol Invest"},{"key":"10.1016\/j.endien.2022.08.002_bib0225","doi-asserted-by":"crossref","first-page":"842","DOI":"10.1016\/S0022-3476(70)80245-1","article-title":"Congenital hyperparathyroidism secondary to maternal hypoparathyroidism","volume":"77","author":"Landing","year":"1970","journal-title":"J Pediatr"},{"key":"10.1016\/j.endien.2022.08.002_bib0230","series-title":"Dietary Reference Intakes: The Essential Guide to Nutrient Requirements","first-page":"1344","author":"Institute of Medicine","year":"2006"},{"year":"2013","series-title":"Guideline: Calcium Supplementation in Pregnant Women","author":"WHO","key":"10.1016\/j.endien.2022.08.002_bib0235"},{"key":"10.1016\/j.endien.2022.08.002_bib0240","first-page":"116","article-title":"Micronutrients in women\u2019s reproductive health: II. Minerals and trace elements","volume":"51","author":"Kontic-Vucinic","year":"2006","journal-title":"Int J Fertil Womens Med"},{"key":"10.1016\/j.endien.2022.08.002_bib0245","doi-asserted-by":"crossref","first-page":"f1169","DOI":"10.1136\/bmj.f1169","article-title":"Association between maternal serum 25-hydroxyvitamin D level and pregnancy and neonatal outcomes: systematic review and meta-analysis of observational studies","volume":"346","author":"Aghajafari","year":"2013","journal-title":"BMJ"},{"key":"10.1016\/j.endien.2022.08.002_bib0250","doi-asserted-by":"crossref","first-page":"443","DOI":"10.3390\/nu11020443","article-title":"Macronutrient and micronutrient intake during pregnancy: an overview of recent evidence","volume":"11","author":"Mousa","year":"2019","journal-title":"Nutrients"},{"key":"10.1016\/j.endien.2022.08.002_bib0255","doi-asserted-by":"crossref","DOI":"10.1210\/clinem\/dgaa306","article-title":"Osteoporosis in premenopausal women: a clinical narrative review by the ECTS and the IOF","volume":"105","author":"Pepe","year":"2020","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.endien.2022.08.002_bib0260","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1007\/s00198-018-4672-9","article-title":"Pregnancy and newborn utcomes after exposure to bisphosphonates: a casecontrol study","volume":"30","author":"Sokal","year":"2019","journal-title":"Osteoporos Int"},{"key":"10.1016\/j.endien.2022.08.002_bib0265","doi-asserted-by":"crossref","first-page":"863","DOI":"10.1016\/j.tjog.2017.10.028","article-title":"Teriparatide and denosumab treatment for pregnancy and lactation-associated osteoporosis with multiple vertebral fractures: a case study","volume":"56","author":"Ijuin","year":"2017","journal-title":"Taiwan J Obstet Gynecol"},{"key":"10.1016\/j.endien.2022.08.002_bib0270","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1016\/j.bone.2014.04.002","article-title":"Infant cynomolgus monkeys exposed to denosumab in utero exhibit an osteoclast-poor osteopetrotic like skeletal phenotype at birth and in the early postnatal period","volume":"64","author":"Boyce","year":"2014","journal-title":"Bone"},{"key":"10.1016\/j.endien.2022.08.002_bib0275","doi-asserted-by":"crossref","first-page":"100706","DOI":"10.1016\/j.bonr.2020.100706","article-title":"A case of pregnancy and lactation associated osteoporosis in the third pregnancy; robust response to teriparatide despite delayed administration","volume":"13","author":"Cerit","year":"2020","journal-title":"Bone Rep"}],"container-title":["Endocrinolog\u00eda, Diabetes y Nutrici\u00f3n (English ed.)"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2530018022001330?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2530018022001330?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,11]],"date-time":"2025-11-11T13:16:10Z","timestamp":1762866970000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2530018022001330"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,8]]},"references-count":55,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2022,8]]}},"alternative-id":["S2530018022001330"],"URL":"https:\/\/doi.org\/10.1016\/j.endien.2022.08.002","relation":{},"ISSN":["2530-0180"],"issn-type":[{"type":"print","value":"2530-0180"}],"subject":[],"published":{"date-parts":[[2022,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Guide of management of alterations in mineral and bone metabolism during gestation and lactation","name":"articletitle","label":"Article Title"},{"value":"Endocrinolog\u00eda, Diabetes y Nutrici\u00f3n (English ed.)","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.endien.2022.08.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"https:\/\/doi.org\/10.1016\/j.endinu.2021.10.012","name":"associatedlink","label":"CrossRef DOI link to the associated document"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Published by Elsevier Espa\u00f1a, S.L.U. on behalf of SEEN and SED.","name":"copyright","label":"Copyright"}]}}