{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T21:29:57Z","timestamp":1788470997910,"version":"build-2803163510"},"reference-count":32,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,6,1]],"date-time":"2023-06-01T00:00:00Z","timestamp":1685577600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,6,1]],"date-time":"2023-06-01T00:00:00Z","timestamp":1685577600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Endocrinolog\u00eda, Diabetes y Nutrici\u00f3n (English ed.)"],"published-print":{"date-parts":[[2023,6]]},"DOI":"10.1016\/j.endien.2022.11.025","type":"journal-article","created":{"date-parts":[[2023,5,31]],"date-time":"2023-05-31T04:12:19Z","timestamp":1685506339000},"page":"35-44","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"special_numbering":"S2","title":["Preoperative parathyroid localization. Relevance of MIBI SPECT-CT in adverse scenarios"],"prefix":"10.1016","volume":"70","author":[{"given":"Isabel","family":"Blanco-Saiz","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elena","family":"Go\u00f1i-Giron\u00e9s","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mar\u00eda Jes\u00fas","family":"Ribelles-Segura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pilar","family":"Salvador-Egea","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mar\u00eda","family":"D\u00edaz-Tobarra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alicia","family":"Camarero-Salazar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nikola","family":"Rudic-Chipe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabel","family":"Saura-L\u00f3pez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alberto","family":"Alomar-Casanovas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angel","family":"Rabines-Ju\u00e1rez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Javier","family":"Garc\u00eda-Torres","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Enma","family":"Anda-Api\u00f1\u00e1niz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.endien.2022.11.025_bib0165","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1016\/S0140-6736(17)31430-7","article-title":"Hyperparathyroidism","volume":"391","author":"Bilezikian","year":"2018","journal-title":"Lancet"},{"key":"10.1016\/j.endien.2022.11.025_bib0170","doi-asserted-by":"crossref","first-page":"959","DOI":"10.1001\/jamasurg.2016.2310","article-title":"The American association of endocrine surgeons guidelines for definitive management of primary hyperparathyroidism","volume":"151","author":"Wilhelm","year":"2016","journal-title":"JAMA Surg"},{"key":"10.1016\/j.endien.2022.11.025_bib0175","doi-asserted-by":"crossref","first-page":"3561","DOI":"10.1210\/jc.2014-1413","article-title":"Guidelines for the management of asymptomatic primary hyperparathyroidism: summary statement from the fourth international workshop","volume":"99","author":"Bilezikian","year":"2014","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.endien.2022.11.025_bib0180","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1097\/SLA.0b013e3181f698df","article-title":"Operative failures after parathyroidectomy for hyperparathyroidism: the influence of surgical volume","volume":"252","author":"Chen","year":"2010","journal-title":"Ann Surg"},{"key":"10.1016\/j.endien.2022.11.025_bib0185","first-page":"CD010787","article-title":"Minimally invasive parathyroidectomy guided by intraoperative parathyroid hormone monitoring (IOPTH) and preoperative imaging versus bilateral neck exploration for primary hyperparathyroidism in adults","volume":"2020","author":"Ahmadieh","year":"2020","journal-title":"Cochrane Database Syst Rev"},{"key":"10.1016\/j.endien.2022.11.025_bib0190","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1002\/bjs5.77","article-title":"Systematic review of cure and recurrence rates following minimally invasive parathyroidectomy","volume":"2","author":"Ishii","year":"2018","journal-title":"BJS Open"},{"key":"10.1016\/j.endien.2022.11.025_bib0195","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1097\/SLA.0b013e318208fed9","article-title":"The superiority of minimally invasive parathyroidectomy based on 1650 consecutive patients with primary hyperparathyroidism","volume":"253","author":"Udelsman","year":"2011","journal-title":"Ann Surg"},{"key":"10.1016\/j.endien.2022.11.025_bib0200","doi-asserted-by":"crossref","first-page":"737","DOI":"10.2967\/jnumed.115.156018","article-title":"The role of radionuclide imaging in the surgical management of primary hyperparathyroidism, Journal of nuclear medicine: official publication","volume":"56","author":"Hindi\u00e9","year":"2015","journal-title":"Soc Nucl Med"},{"key":"10.1016\/j.endien.2022.11.025_bib0205","doi-asserted-by":"crossref","first-page":"2801","DOI":"10.1007\/s00259-021-05334-y","article-title":"The EANM practice guidelines for parathyroid imaging","volume":"48","author":"Petranovi\u0107 Ov\u010dari\u010dek","year":"2021","journal-title":"Eur J Nucl Med Mol Imaging"},{"key":"10.1016\/j.endien.2022.11.025_bib0210","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1530\/EJE-14-0964","article-title":"Preoperative imaging for focused parathyroidectomy: making a good strategy even better","volume":"172","author":"Guerin","year":"2015","journal-title":"Eur J Endocrinol"},{"issue":"Suppl. 1","key":"10.1016\/j.endien.2022.11.025_bib0215","first-page":"E2159","article-title":"Detection rate of (99m) Tc-MIBI single photon emission computed tomography (SPECT)\/CT in preoperative planning for patients with primary hyperparathyroidism: a meta-analysis","volume":"38","author":"Treglia","year":"2016","journal-title":"Head Neck"},{"key":"10.1016\/j.endien.2022.11.025_bib0220","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1016\/j.remn.2016.07.004","article-title":"Hybrid-fusion SPECT\/CT systems in parathyroid adenoma: technological improvements and added clinical diagnostic value","volume":"35","author":"Wong","year":"2016","journal-title":"Revista Espa\u00f1ola de Medicina Nuclear e Imagen Molecular (Engl Ed)"},{"key":"10.1016\/j.endien.2022.11.025_bib0225","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1007\/s12020-020-02487-y","article-title":"Will (18)F-fluorocholine PET\/CT replace other methods of preoperative parathyroid imaging?","volume":"71","author":"Giovanella","year":"2021","journal-title":"Endocrine"},{"key":"10.1016\/j.endien.2022.11.025_bib0230","doi-asserted-by":"crossref","first-page":"1201","DOI":"10.1007\/s00259-009-1131-z","article-title":"2009 EANM parathyroid guidelines","volume":"36","author":"Hindi\u00e9","year":"2009","journal-title":"Eur J Nucl Med Mol Imaging"},{"key":"10.1016\/j.endien.2022.11.025_bib0235","doi-asserted-by":"crossref","first-page":"26","DOI":"10.4158\/EP11089.OR","article-title":"Thyroid-related factors that influence preoperative localization of parathyroid adenomas","volume":"18","author":"Isik","year":"2012","journal-title":"Endocr Pract"},{"key":"10.1016\/j.endien.2022.11.025_bib0240","doi-asserted-by":"crossref","first-page":"1617","DOI":"10.1002\/hed.25023","article-title":"AHNS Series: do you know your guidelines? Optimizing outcomes in reoperative parathyroid surgery: definitive multidisciplinary joint consensus guidelines of the American Head and Neck Society and the British Association of Endocrine and Thyroid Surgeons","volume":"40","author":"Stack","year":"2018","journal-title":"Head Neck"},{"key":"10.1016\/j.endien.2022.11.025_bib0245","doi-asserted-by":"crossref","first-page":"3831","DOI":"10.1245\/s10434-020-08428-3","article-title":"Utility of a second 99mTc-MIBI scintigraphy before reoperation for patients with persistent sporadic primary hyperparathyroidism: results of a retrospective multicenter study","volume":"27","author":"Frey","year":"2020","journal-title":"Ann Surg Oncol"},{"key":"10.1016\/j.endien.2022.11.025_bib0250","doi-asserted-by":"crossref","first-page":"566","DOI":"10.1007\/s00268-007-9389-4","article-title":"Impact of adenoma weight and ectopic location of parathyroid adenoma on localization study results","volume":"32","author":"Erbil","year":"2008","journal-title":"World J Surg"},{"key":"10.1016\/j.endien.2022.11.025_bib0255","doi-asserted-by":"crossref","first-page":"836","DOI":"10.1177\/0300060518813742","article-title":"99m TcO4-\/99m Tc-MIBI dual-tracer scintigraphy for preoperative localization of parathyroid adenomas","volume":"47","author":"Huang","year":"2019","journal-title":"J Int Med Res"},{"key":"10.1016\/j.endien.2022.11.025_bib0260","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1016\/j.crad.2009.12.005","article-title":"Clinical utility of ultrasound and 99mTc sestamibi SPECT\/CT for preoperative localization of parathyroid adenoma in patients with primary hyperparathyroidism","volume":"65","author":"Patel","year":"2010","journal-title":"Clin Radiol"},{"key":"10.1016\/j.endien.2022.11.025_bib0265","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1111\/cen.12835","article-title":"Parathyroid surgery: correlation between pre-operative localization studies and surgical outcomes","volume":"83","author":"Ebner","year":"2015","journal-title":"Clin Endocrinol"},{"key":"10.1016\/j.endien.2022.11.025_bib0270","first-page":"18","article-title":"Two cases of spontaneous remission of primary hyperparathyroidism due to auto-infarction: different management and their outcomes","volume":"7","author":"Novodvorsky","year":"2019","journal-title":"Endocrinol Diab Metab Case Rep"},{"key":"10.1016\/j.endien.2022.11.025_bib0275","doi-asserted-by":"crossref","first-page":"e109","DOI":"10.1097\/RLU.0000000000001447","article-title":"SPECT\/CT's advantage for preoperative localization of small parathyroid adenomas in primary hyperparathyroidism","volume":"42","author":"Sandqvist","year":"2017","journal-title":"Clin Nucl Med"},{"key":"10.1016\/j.endien.2022.11.025_bib0280","doi-asserted-by":"crossref","first-page":"1084","DOI":"10.2967\/jnumed.107.040428","article-title":"Comparison of SPECT\/CT, SPECT, and planar imaging with single- and dual-phase 99mTc-sestamibi parathyroid scintigraphy","volume":"48","author":"Lavely","year":"2007","journal-title":"J Nucl Med"},{"key":"10.1016\/j.endien.2022.11.025_bib0285","first-page":"1028","article-title":"Clinical impact of SPECT-CT in the diagnosis and surgical management of hyper-parathyroidism","volume":"7","author":"Tokmak","year":"2014","journal-title":"Int J Clin Exp Med"},{"key":"10.1016\/j.endien.2022.11.025_bib0290","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1007\/s11307-016-1013-2","article-title":"Preoperative [99mTc]MIBI SPECT\/CT interpretation criteria for localization of parathyroid adenomas\u2014correlation with surgical findings","volume":"19","author":"Keidar","year":"2017","journal-title":"Mol Imaging Biol"},{"key":"10.1016\/j.endien.2022.11.025_bib0295","doi-asserted-by":"crossref","first-page":"1070","DOI":"10.1097\/MNM.0b013e32835710b6","article-title":"Preoperative 99mTc-sestamibi scintigraphy in patients with primary hyperparathyroidism and concomitant nodular goiter: comparison of SPECT-CT, SPECT, and planar imaging","volume":"33","author":"Shafiei","year":"2012","journal-title":"Nucl Med Commun"},{"key":"10.1016\/j.endien.2022.11.025_bib0300","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1177\/000313480306900507","article-title":"Impact of hypercalcemia and parathyroid hormone level on the sensitivity of preoperative sestamibi scanning for primary hyperparathyroidism","volume":"69","author":"Parikshak","year":"2003","journal-title":"Am Surg"},{"key":"10.1016\/j.endien.2022.11.025_bib0305","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1016\/j.amjsurg.2007.01.040","article-title":"The positive effect of adenoma weight and oxyphil cell content on preoperative localization with 99mTc-sestamibi scanning for primary hyperparathyroidism","volume":"195","author":"Erbil","year":"2008","journal-title":"Am J Surg"},{"key":"10.1016\/j.endien.2022.11.025_bib0310","doi-asserted-by":"crossref","first-page":"1717","DOI":"10.1245\/s10434-010-1493-2","article-title":"Primary hyperparathyroidism patients with positive preoperative sestamibi scan and negative ultrasound are more likely to have posteriorly located upper gland adenomas (PLUGs)","volume":"18","author":"Harari","year":"2011","journal-title":"Ann Surg Oncol"},{"key":"10.1016\/j.endien.2022.11.025_bib0315","first-page":"272","article-title":"High capacity of ultrasound for locating parathyroid adenomas in endocrinology (the ETIEN 4 study)","volume":"67","author":"Carral","year":"2020","journal-title":"Endocrinol Diab Nutr"},{"key":"10.1016\/j.endien.2022.11.025_bib0320","doi-asserted-by":"crossref","first-page":"1129","DOI":"10.1097\/MNM.0000000000000921","article-title":"Comparison between technetium-99m methoxyisobutylisonitrile scintigraphy and ultrasound in the diagnosis of parathyroid adenoma and parathyroid hyperplasia","volume":"39","author":"Xue","year":"2018","journal-title":"Nucl Med Commun"}],"container-title":["Endocrinolog\u00eda, Diabetes y Nutrici\u00f3n (English ed.)"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2530018022002037?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2530018022002037?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,11]],"date-time":"2025-11-11T13:17:01Z","timestamp":1762867021000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2530018022002037"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,6]]},"references-count":32,"alternative-id":["S2530018022002037"],"URL":"https:\/\/doi.org\/10.1016\/j.endien.2022.11.025","relation":{},"ISSN":["2530-0180"],"issn-type":[{"value":"2530-0180","type":"print"}],"subject":[],"published":{"date-parts":[[2023,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Preoperative parathyroid localization. Relevance of MIBI SPECT-CT in adverse scenarios","name":"articletitle","label":"Article Title"},{"value":"Endocrinolog\u00eda, Diabetes y Nutrici\u00f3n (English ed.)","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.endien.2022.11.025","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 SEEN and SED. Published by Elsevier Espa\u00f1a, S.L.U. All rights reserved.","name":"copyright","label":"Copyright"}]}}