{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T21:25:48Z","timestamp":1781645148312,"version":"3.54.5"},"reference-count":28,"publisher":"Elsevier BV","issue":"9","license":[{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.es","clinicalkey.com.au","clinicalkey.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Endocrinolog\u00eda, Diabetes y Nutrici\u00f3n (English ed.)"],"published-print":{"date-parts":[[2024,11]]},"DOI":"10.1016\/j.endien.2024.11.003","type":"journal-article","created":{"date-parts":[[2024,11,15]],"date-time":"2024-11-15T21:27:34Z","timestamp":1731706054000},"page":"380-389","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"title":["Minimally invasive techniques for the management of benign thyroid nodules: Efficacy and impact on quality of life of percutaneous ethanol injection. Results from a high-resolution thyroid nodule unit"],"prefix":"10.1016","volume":"71","author":[{"given":"Javier","family":"Bodoque Cubas","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9","family":"Fern\u00e1ndez S\u00e1ez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sergio","family":"Mart\u00ednez Herv\u00e1s","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9 Vicente","family":"Gil Boix","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan Jos\u00e9","family":"Salazar Gonz\u00e1lez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raquel Mar\u00eda","family":"Pallar\u00e9s Gassulla","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sara","family":"Mart\u00ednez P\u00e9rez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcel","family":"la Miret Llaurad\u00f3","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I\u00f1aki","family":"Arg\u00fcelles Jim\u00e9nez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Santiago","family":"Tof\u00e9 Povedano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.endien.2024.11.003_bib0005","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1089\/thy.2015.0020","article-title":"2015 American thyroid association management guidelines for adult patients with thyroid nodules and differentiated thyroid cancer: the American thyroid association guidelines task force on thyroid nodules and differentiated thyroid cancer","volume":"26","author":"Haugen","year":"2016","journal-title":"Thyroid"},{"key":"10.1016\/j.endien.2024.11.003_bib0010","doi-asserted-by":"crossref","first-page":"919","DOI":"10.1001\/jama.2018.0898","article-title":"The diagnosis and management of thyroid nodules: a review","volume":"319","author":"Durante","year":"2018","journal-title":"JAMA"},{"key":"10.1016\/j.endien.2024.11.003_bib0015","doi-asserted-by":"crossref","first-page":"540","DOI":"10.1016\/S2213-8587(22)00139-5","article-title":"Management of thyroid nodules","volume":"10","author":"Alexander","year":"2022","journal-title":"Lancet Diabetes Endocrinol"},{"key":"10.1016\/j.endien.2024.11.003_bib0020","doi-asserted-by":"crossref","first-page":"R133","DOI":"10.1530\/EJE-13-0917","article-title":"DIAGNOSIS OF ENDOCRINE DISEASE: thyroid ultrasound (US) and US-assisted procedures: from the shadows into an array of applications","volume":"170","author":"Papini","year":"2014","journal-title":"Eur J Endocrinol"},{"key":"10.1016\/j.endien.2024.11.003_bib0025","doi-asserted-by":"crossref","first-page":"2103","DOI":"10.1002\/hed.25181","article-title":"Image\u2010guided chemical and thermal ablations for thyroid disease: review of efficacy and complications","volume":"40","author":"Nixon","year":"2018","journal-title":"Head Neck"},{"key":"10.1016\/j.endien.2024.11.003_bib0030","doi-asserted-by":"crossref","first-page":"468","DOI":"10.4158\/EP.16.3.468","article-title":"American Association of Clinical Endocrinologists, Associazione Medici Endocrinologi, and European Thyroid Association Medical Guidelines for clinical practice for the diagnosis and management of thyroid nodules: executive summary of recommendations","volume":"16","author":"Gharib","year":"2010","journal-title":"Endocrine Practice"},{"key":"10.1016\/j.endien.2024.11.003_bib0035","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3348\/kjr.2011.12.1.1","article-title":"Ultrasonography and the ultrasound-based management of thyroid nodules: consensus statement and recommendations","volume":"12","author":"Moon","year":"2011","journal-title":"Korean J Radiol"},{"key":"10.1016\/j.endien.2024.11.003_bib0040","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1530\/EJE-20-0213","article-title":"Long-term follow-up of cystic thyroid nodules treated with percutaneous ethanol injection (PEI) using two different approaches","volume":"183","author":"Deandrea","year":"2020","journal-title":"Eur J Endocrinol"},{"key":"10.1016\/j.endien.2024.11.003_bib0045","doi-asserted-by":"crossref","first-page":"204","DOI":"10.14366\/usg.21003","article-title":"Assessment of thyroid-specific quality of life in patients with benign symptomatic thyroid nodules treated with radiofrequency or ethanol ablation: a prospective multicenter study","volume":"41","author":"Jeong","year":"2022","journal-title":"Ultrasonography"},{"key":"10.1016\/j.endien.2024.11.003_bib0050","doi-asserted-by":"crossref","first-page":"500","DOI":"10.1016\/j.endinu.2018.06.010","article-title":"Adaptation and cross-cultural validation of the Spanish version of the thyroid-related quality-of-life patient-reported outcome questionnaire","volume":"65","author":"Boronat","year":"2018","journal-title":"Endocrinol Diabetes Nutr"},{"key":"10.1016\/j.endien.2024.11.003_bib0055","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1530\/EJE-09-0521","article-title":"Validity and reliability of the novel thyroid-specific quality of life questionnaire, ThyPRO","volume":"162","author":"Watt","year":"2010","journal-title":"Eur J Endocrinol"},{"key":"10.1016\/j.endien.2024.11.003_bib0060","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1159\/000508484","article-title":"2020 European Thyroid Association Clinical Practice Guideline for the use of image-guided ablation in benign thyroid nodules","volume":"9","author":"Papini","year":"2020","journal-title":"Eur Thyroid J"},{"key":"10.1016\/j.endien.2024.11.003_bib0065","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1016\/j.jacr.2017.01.046","article-title":"ACR Thyroid Imaging, Reporting and Data System (TI-RADS): white paper of the ACR TI-RADS committee","volume":"14","author":"Tessler","year":"2017","journal-title":"J Am Coll Radiol"},{"key":"10.1016\/j.endien.2024.11.003_bib0070","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1089\/thy.1996.6.403","article-title":"Percutaneous ethanol injection of large thyroid cystic nodules","volume":"6","author":"Zingrillo","year":"1996","journal-title":"Thyroid"},{"key":"10.1016\/j.endien.2024.11.003_bib0075","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1186\/s12902-015-0069-3","article-title":"Evaluation of efficacy, safety, pain perception and health-related quality of life of percutaneous ethanol injection as first-line treatment in symptomatic thyroid cysts","volume":"15","author":"Reverter","year":"2015","journal-title":"BMC Endocr Disord"},{"key":"10.1016\/j.endien.2024.11.003_bib0080","doi-asserted-by":"crossref","first-page":"269","DOI":"10.4158\/EP.10.3.269","article-title":"Ultrasound-guided percutaneous ethanol injection therapy in thyroid cystic nodules","volume":"10","author":"Valcavi","year":"2004","journal-title":"Endocrine Practice"},{"key":"10.1016\/j.endien.2024.11.003_bib0085","doi-asserted-by":"crossref","first-page":"958","DOI":"10.1007\/BF02067001","article-title":"Treatment of cystic lesions of the thyroid by ethanol instillation","volume":"16","author":"Yasuda","year":"1992","journal-title":"World J Surg"},{"key":"10.1016\/j.endien.2024.11.003_bib0090","doi-asserted-by":"crossref","first-page":"417","DOI":"10.14366\/usg.20170","article-title":"Ultrasound-guided ethanol ablation for cystic thyroid nodules: effectiveness of small amounts of ethanol in a single session","volume":"40","author":"Cho","year":"2021","journal-title":"Ultrasonography"},{"key":"10.1016\/j.endien.2024.11.003_bib0095","doi-asserted-by":"crossref","first-page":"609","DOI":"10.3348\/kjr.2018.0696","article-title":"Ethanol ablation of the thyroid nodules: 2018 consensus statement by the Korean Society of Thyroid Radiology","volume":"20","author":"Hahn","year":"2019","journal-title":"Korean J Radiol"},{"key":"10.1016\/j.endien.2024.11.003_bib0100","first-page":"2122","article-title":"Percutaneous ethanol injection for benign cystic thyroid nodules: is aspiration of ethanol-mixed fluid advantageous?","volume":"26","author":"Kim","year":"2005","journal-title":"AJNR Am J Neuroradiol"},{"key":"10.1016\/j.endien.2024.11.003_bib0105","doi-asserted-by":"crossref","first-page":"166","DOI":"10.14366\/usg.18033","article-title":"Ethanol ablation as a treatment strategy for benign cystic thyroid nodules: a comparison of the ethanol retention and aspiration techniques","volume":"38","author":"Park","year":"2019","journal-title":"Ultrasonography"},{"key":"10.1016\/j.endien.2024.11.003_bib0110","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1055\/s-2005-857867","article-title":"Complications of ultrasound guided percutaneous ethanol injection therapy of the thyroid and parathyroid glands","volume":"26","author":"Mauz","year":"2005","journal-title":"Ultraschall Med"},{"key":"10.1016\/j.endien.2024.11.003_bib0115","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1016\/j.crad.2014.09.008","article-title":"Ethanol ablation of predominantly cystic thyroid nodules: evaluation of recurrence rate and factors related to recurrence","volume":"70","author":"Suh","year":"2015","journal-title":"Clin Radiol"},{"key":"10.1016\/j.endien.2024.11.003_bib0120","doi-asserted-by":"crossref","first-page":"1573","DOI":"10.1007\/s00330-012-2406-5","article-title":"Cystic versus predominantly cystic thyroid nodules: efficacy of ethanol ablation and analysis of related factors","volume":"22","author":"Kim","year":"2012","journal-title":"Eur Radiol"},{"key":"10.1016\/j.endien.2024.11.003_bib0125","doi-asserted-by":"crossref","first-page":"905","DOI":"10.1016\/j.ejrad.2011.02.039","article-title":"How to manage the patients with unsatisfactory results after ethanol ablation for thyroid nodules: role of radiofrequency ablation","volume":"81","author":"Jang","year":"2012","journal-title":"Eur J Radiol"},{"key":"10.1016\/j.endien.2024.11.003_bib0130","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1507\/endocrj.52.455","article-title":"Effectiveness of percutaneous ethanol injection therapy in benign nodular and cystic thyroid diseases: long-term follow-up experience","volume":"52","author":"Lee","year":"2005","journal-title":"Endocr J"},{"key":"10.1016\/j.endien.2024.11.003_bib0135","doi-asserted-by":"crossref","first-page":"974","DOI":"10.1016\/j.amjsurg.2013.05.005","article-title":"Quality of life after thyroid surgery in women with benign euthyroid goiter: influencing factors including Hashimoto\u2019s thyroiditis","volume":"207","author":"Promberger","year":"2014","journal-title":"Am J Surg"},{"key":"10.1016\/j.endien.2024.11.003_bib0140","doi-asserted-by":"crossref","first-page":"1157","DOI":"10.1007\/s00423-011-0822-7","article-title":"Quality of life is not influenced by the extent of surgery in patients with benign goiter","volume":"396","author":"Schmitz-Winnenthal","year":"2011","journal-title":"Langenbecks Arch Surg"}],"container-title":["Endocrinolog\u00eda, Diabetes y Nutrici\u00f3n (English ed.)"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2530018024001094?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2530018024001094?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,11,27]],"date-time":"2024-11-27T07:01:47Z","timestamp":1732690907000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2530018024001094"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,11]]},"references-count":28,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2024,11]]}},"alternative-id":["S2530018024001094"],"URL":"https:\/\/doi.org\/10.1016\/j.endien.2024.11.003","relation":{},"ISSN":["2530-0180"],"issn-type":[{"value":"2530-0180","type":"print"}],"subject":[],"published":{"date-parts":[[2024,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Minimally invasive techniques for the management of benign thyroid nodules: Efficacy and impact on quality of life of percutaneous ethanol injection. Results from a high-resolution thyroid nodule unit","name":"articletitle","label":"Article Title"},{"value":"Endocrinolog\u00eda, Diabetes y Nutrici\u00f3n (English ed.)","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.endien.2024.11.003","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"https:\/\/doi.org\/10.1016\/j.endinu.2024.05.011","name":"associatedlink","label":"CrossRef DOI link to the associated document"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 SEEN and SED. Published by Elsevier Espa\u00f1a, S.L.U. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}