{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,25]],"date-time":"2026-01-25T05:05:40Z","timestamp":1769317540521,"version":"3.49.0"},"reference-count":40,"publisher":"Elsevier BV","issue":"8","license":[{"start":{"date-parts":[[2019,10,1]],"date-time":"2019-10-01T00:00:00Z","timestamp":1569888000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,10,1]],"date-time":"2019-10-01T00:00:00Z","timestamp":1569888000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.es","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Endocrinolog\u00eda, Diabetes y Nutrici\u00f3n"],"published-print":{"date-parts":[[2019,10]]},"DOI":"10.1016\/j.endinu.2019.03.019","type":"journal-article","created":{"date-parts":[[2019,6,7]],"date-time":"2019-06-07T22:35:49Z","timestamp":1559946949000},"page":"502-511","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":10,"title":["ApoB\/ApoA1 ratio and non-HDL-cholesterol\/HDL-cholesterol ratio are associated to metabolic syndrome in patients with type 2 diabetes mellitus subjects and to ischemic cardiomyopathy in diabetic women"],"prefix":"10.1016","volume":"66","author":[{"given":"Gabriela Lizet","family":"Reynoso-Villalpando","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cristina","family":"Sevillano-Collantes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yeminia","family":"Valle","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Inmaculada","family":"Moreno-Ruiz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jorge Ram\u00f3n","family":"Padilla-Guti\u00e9rrez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francisco Javier","family":"del Ca\u00f1izo-G\u00f3mez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.endinu.2019.03.019_bib0205","doi-asserted-by":"crossref","first-page":"615","DOI":"10.1007\/s00592-013-0468-8","article-title":"Prevalence of the metabolic syndrome in Spain using regional cutoff points for waist circumference: the diabetes study","volume":"50","author":"Marcuello","year":"2013","journal-title":"Acta Diabetol"},{"key":"10.1016\/j.endinu.2019.03.019_bib0210","first-page":"2486e2489","article-title":"Expert panel on detection, evaluation, and treatment of high blood cholesterol in adults (Adult Treatment Panel III)","volume":"285","year":"2001","journal-title":"JAMA"},{"key":"10.1016\/j.endinu.2019.03.019_bib0215","doi-asserted-by":"crossref","first-page":"2444","DOI":"10.2337\/diacare.27.10.2444","article-title":"Increasing prevalence of the metabolic syndrome among U.S. adults","volume":"27","author":"Ford","year":"2004","journal-title":"Diabetes Care"},{"issue":"Suppl. 1","key":"10.1016\/j.endinu.2019.03.019_bib0220","doi-asserted-by":"crossref","first-page":"S33","DOI":"10.1016\/j.metabol.2014.10.028","article-title":"Biomarkers of cardiovascular disease risk in women","volume":"64","author":"Manson","year":"2015","journal-title":"Metabolism"},{"key":"10.1016\/j.endinu.2019.03.019_bib0225","doi-asserted-by":"crossref","first-page":"2004","DOI":"10.1056\/NEJMra1216063","article-title":"Mechanisms of acute coronary syndromes and their implications for therapy","volume":"368","author":"Libby","year":"2013","journal-title":"N Engl J Med"},{"key":"10.1016\/j.endinu.2019.03.019_bib0230","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1007\/s12020-012-9599-x","article-title":"The relationship between high-sensitivity C-reactive protein and ApoB, ApoB\/ApoA1 ratio in general population of China","volume":"42","author":"Xu","year":"2012","journal-title":"Endocrine"},{"key":"10.1016\/j.endinu.2019.03.019_bib0235","first-page":"69","article-title":"Prote\u00edna C reactiva y enfermedad arterial coronaria","volume":"17","author":"Heres \u00c1lvarez","year":"2011","journal-title":"Rev Cubana Cardiol Cir Cardiovasc"},{"key":"10.1016\/j.endinu.2019.03.019_bib0240","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1016\/j.imr.2016.07.001","article-title":"High-density lipoprotein cholesterol (HDL-C) in cardiovascular disease: effect of exercise training","volume":"5","author":"Ahn","year":"2016","journal-title":"Integr Med Res"},{"key":"10.1016\/j.endinu.2019.03.019_bib0245","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1007\/s12291-015-0513-1","article-title":"Apolipoprotein A-I: a molecule of diverse function","volume":"31","author":"Mangaraj","year":"2016","journal-title":"Indian J Clin Biochem"},{"key":"10.1016\/j.endinu.2019.03.019_bib0250","doi-asserted-by":"crossref","first-page":"699","DOI":"10.1111\/j.1365-2265.2012.04329.x","article-title":"The value of apolipoprotein B\/A1 ratio in the diagnosis of metabolic syndrome in a Korean population","volume":"77","author":"Jung","year":"2012","journal-title":"Clin Endocrinol (Oxf)"},{"issue":"F1000 Faculty Rev","key":"10.1016\/j.endinu.2019.03.019_bib0255","doi-asserted-by":"crossref","first-page":"134","DOI":"10.12688\/f1000research.9845.1","article-title":"Apolipoprotein B-containing lipoproteins and atherosclerotic cardiovascular disease [version 1; referees: 2 approved]","volume":"6","author":"Shapiro","year":"2017","journal-title":"F1000 Res"},{"key":"10.1016\/j.endinu.2019.03.019_bib0260","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1111\/j.1365-2796.2006.01643.x","article-title":"The apoB\/apoA-I ratio: a strong, new risk factor for cardiovascular disease and a target for lipid-lowering therapy \u2013 a review of the evidence","volume":"259","author":"Walldius","year":"2006","journal-title":"J Intern Med"},{"key":"10.1016\/j.endinu.2019.03.019_bib0265","doi-asserted-by":"crossref","first-page":"e5834","DOI":"10.1097\/MD.0000000000005834","article-title":"The nonlinear association between apolipoprotein B to apolipoprotein A1 ratio and type 2 diabetes","volume":"96","author":"Mao","year":"2017","journal-title":"Medicine (Baltimore)"},{"key":"10.1016\/j.endinu.2019.03.019_bib0270","doi-asserted-by":"crossref","first-page":"1165","DOI":"10.1111\/j.1464-5491.2012.03622.x","article-title":"Increased apoB\/A-I ratio independently associated with type 2 diabetes mellitus: cross-sectional study in a Korean population","volume":"29","author":"Hwang","year":"2012","journal-title":"Diabet Med"},{"key":"10.1016\/j.endinu.2019.03.019_bib0275","doi-asserted-by":"crossref","first-page":"2637","DOI":"10.1093\/eurheartj\/ehm360","article-title":"ApoB\/apoA-I ratio: an independent predictor of insulin resistance in US non-diabetic subjects","volume":"28","author":"Sierra-Johnson","year":"2007","journal-title":"Eur Heart J"},{"key":"10.1016\/j.endinu.2019.03.019_bib0280","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1186\/s12933-014-0146-3","article-title":"Clinical usefulness of lipid ratios, visceral adiposity indicators, and the triglycerides and glucose index as risk markers of insulin resistance","volume":"13","author":"Du","year":"2014","journal-title":"Cardiovasc Diabetol"},{"key":"10.1016\/j.endinu.2019.03.019_bib0285","doi-asserted-by":"crossref","first-page":"2026","DOI":"10.1016\/S0140-6736(01)07098-2","article-title":"High apolipoprotein B, low apolipoprotein A1, and improvement in the prediction of fatal myocardial infarction (AMORIS study): a prospective study","volume":"358","author":"Walldius","year":"2001","journal-title":"Lancet"},{"key":"10.1016\/j.endinu.2019.03.019_bib0290","doi-asserted-by":"crossref","DOI":"10.1186\/1476-511X-13-81","article-title":"The value of Apolipoprotein B\/Apolipoprotein A1 ratio for metabolic syndrome diagnosis in a Chinese population: a cross-sectional study","author":"Jing","year":"2014","journal-title":"Lipids Health Dis"},{"key":"10.1016\/j.endinu.2019.03.019_bib0295","doi-asserted-by":"crossref","first-page":"2678","DOI":"10.1016\/j.ijcard.2013.03.027","article-title":"Non-HDL-cholesterol\/HDL-cholesterol is a better predictor of metabolic syndrome and insulin resistance than apolipoprotein B\/apolipoprotein A1","volume":"168","author":"Kim","year":"2013","journal-title":"Int J Cardiol"},{"key":"10.1016\/j.endinu.2019.03.019_bib0300","doi-asserted-by":"crossref","first-page":"140","DOI":"10.2337\/dc14-2441","article-title":"ADA\/European Association for the Study of Diabetes (EASD) position statement on management of hyperglycemia in type 2 diabetes","volume":"38","author":"Inzucchi","year":"2015","journal-title":"Diabetes Care"},{"key":"10.1016\/j.endinu.2019.03.019_bib0305","unstructured":"https:\/\/www.healthcare.siemens.com\/immunoassay\/systems\/adviacentaur-xp."},{"key":"10.1016\/j.endinu.2019.03.019_bib0310","unstructured":"https:\/\/www.healthcare.siemens.com\/integratedchemistry\/systems\/dimension-vista-1500-intel-lab-sys\/assays."},{"key":"10.1016\/j.endinu.2019.03.019_bib0315","unstructured":"http:\/\/www-01.ibm.com\/support\/docview.wss?uid=swg24034354."},{"key":"10.1016\/j.endinu.2019.03.019_bib0320","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1097\/MOL.0000000000000253","article-title":"Apolipoprotein A-I interactions with insulin secretion and production","volume":"27","author":"Rye","year":"2016","journal-title":"Curr Opin Lipidol"},{"key":"10.1016\/j.endinu.2019.03.019_bib0325","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1016\/j.ijcard.2008.12.066","article-title":"The paradox of high apolipoprotein A-I levels independently predicting incident type-2 diabetes among Turks","volume":"142","author":"Onat","year":"2010","journal-title":"Int J Cardiol"},{"key":"10.1016\/j.endinu.2019.03.019_bib0330","article-title":"Assessment of insulin resistance and ApoB\/ApoA1 ratio in type II diabetes patients","volume":"vol. III","author":"Sathvika","year":"2013","journal-title":"Natl J Basic Med Sci"},{"key":"10.1016\/j.endinu.2019.03.019_bib0335","series-title":"The ApoB\/ApoA-I ratio is a strong predictor of cardiovascular risk","author":"Walldius","year":"2012"},{"issue":"Suppl. 1","key":"10.1016\/j.endinu.2019.03.019_bib0340","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s00059-014-4147-5","article-title":"Apolipoprotein B\/apolipoprotein A1 ratio and non-high-density lipoprotein cholesterol. Predictive value for CHD severity and prognostic utility in CHD patients","volume":"40","author":"Liting","year":"2015","journal-title":"Herz"},{"key":"10.1016\/j.endinu.2019.03.019_bib0345","doi-asserted-by":"crossref","first-page":"1261","DOI":"10.1007\/s12098-010-0217-8","article-title":"Utility of ApoB\/ApoA1 ratio for the prediction of cardiovascular risk in children with metabolic syndrome","volume":"77","author":"Savas","year":"2010","journal-title":"Indian J Pediatr"},{"key":"10.1016\/j.endinu.2019.03.019_bib0350","doi-asserted-by":"crossref","first-page":"1081","DOI":"10.1111\/j.1365-2362.2010.02357.x","article-title":"Lipid assessment, metabolic syndrome and coronary heart disease risk","volume":"40","author":"Arsenault","year":"2010","journal-title":"Eur J Clin Invest"},{"key":"10.1016\/j.endinu.2019.03.019_bib0355","doi-asserted-by":"crossref","first-page":"2248","DOI":"10.1161\/01.STR.0000140629.65145.3c","article-title":"Apolipoprotein B\/apolipoprotein A-I in relation to the metabolic syndrome and change in carotid artery intima-media thickness during 3 years in middle-aged men","volume":"35","author":"Wallenfeldt","year":"2004","journal-title":"Stroke"},{"key":"10.1016\/j.endinu.2019.03.019_bib0360","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1007\/s10753-010-9193-4","article-title":"The ApoB\/ApoA1 ratio is associated with metabolic syndrome and its components in a Chinese population","volume":"33","author":"Zhong","year":"2010","journal-title":"Inflammation"},{"key":"10.1016\/j.endinu.2019.03.019_bib0365","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1161\/CIRCGENETICS.113.000630","article-title":"Clinically significant novel biomarkers for prediction of first ever myocardial infarction: the Troms\u00f8 study","volume":"8","author":"Wilsgaard","year":"2015","journal-title":"Circ Cardiovasc Genet"},{"key":"10.1016\/j.endinu.2019.03.019_bib0370","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/j.atherosclerosis.2014.06.029","article-title":"Do apolipoproteins improve coronary risk prediction in subjects with metabolic syndrome? Insights from the North Italian Brianza cohort study","volume":"236","author":"Gianfagna","year":"2014","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.endinu.2019.03.019_bib0375","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1007\/s11010-017-2998-9","article-title":"Analysis of traditional and emerging risk factors in premenopausal women with coronary artery disease: a pilot-scale study from North India","volume":"432","author":"Vijayvergiya","year":"2017","journal-title":"Mol Cell Biochem"},{"key":"10.1016\/j.endinu.2019.03.019_bib0380","article-title":"Apolipoproteins A1 B, and apoB\/apoA1 ratio are associated with first ST-segment elevation myocardial infarction but not with recurrent events during long-term follow-up","author":"Bodde","year":"2018","journal-title":"Clin Res Cardiol"},{"key":"10.1016\/j.endinu.2019.03.019_bib0385","doi-asserted-by":"crossref","first-page":"901","DOI":"10.1177\/0003319713511849","article-title":"Apolipoprotein B\/Apolipoprotein A-I ratio and apolipoprotein B long-term predictors of myocardial infarction in initially healthy middle-aged men\u2014a 13-year follow-up","volume":"65","author":"Schmidt","year":"2014","journal-title":"Angiology"},{"key":"10.1016\/j.endinu.2019.03.019_bib0390","doi-asserted-by":"crossref","first-page":"e003512","DOI":"10.1136\/bmjopen-2013-003512","article-title":"Which lipid measurement should we monitor? An analysis of the LIPID study","volume":"4","author":"Glasziou","year":"2014","journal-title":"BMJ Open"},{"key":"10.1016\/j.endinu.2019.03.019_bib0395","doi-asserted-by":"crossref","first-page":"406","DOI":"10.1016\/j.numecd.2009.11.002","article-title":"ApoB\/apoA-I ratio is better than LDL-C in detecting cardiovascular risk","volume":"21","author":"Carnevale Schianca","year":"2011","journal-title":"Nutr Metab Cardiovasc Dis"},{"key":"10.1016\/j.endinu.2019.03.019_bib0400","first-page":"591454","article-title":"The apolipoprotein B\/apolipoprotein A-I ratio as a potential marker of plasma atherogenicity","volume":"2015","author":"Kaneva","year":"2015","journal-title":"Dis Mark"}],"container-title":["Endocrinolog\u00eda, Diabetes y Nutrici\u00f3n"],"original-title":[],"language":"es","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S253001641930117X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S253001641930117X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,11]],"date-time":"2025-11-11T13:05:38Z","timestamp":1762866338000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S253001641930117X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,10]]},"references-count":40,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2019,10]]}},"alternative-id":["S253001641930117X"],"URL":"https:\/\/doi.org\/10.1016\/j.endinu.2019.03.019","relation":{},"ISSN":["2530-0164"],"issn-type":[{"value":"2530-0164","type":"print"}],"subject":[],"published":{"date-parts":[[2019,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"ApoB\/ApoA1 ratio and non-HDL-cholesterol\/HDL-cholesterol ratio are associated to metabolic syndrome in patients with type 2 diabetes mellitus subjects and to ischemic cardiomyopathy in diabetic women","name":"articletitle","label":"Article Title"},{"value":"Endocrinolog\u00eda, Diabetes y Nutrici\u00f3n","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.endinu.2019.03.019","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 SEEN y SED. Published by Elsevier Espa\u00f1a, S.L.U. All rights reserved.","name":"copyright","label":"Copyright"}]}}