{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T21:09:21Z","timestamp":1792098561714,"version":"4.4.0"},"reference-count":54,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2017,2,1]],"date-time":"2017-02-01T00:00:00Z","timestamp":1485907200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100004613","name":"China Geological Survey","doi-asserted-by":"publisher","award":["1212011121156"],"award-info":[{"award-number":["1212011121156"]}],"id":[{"id":"10.13039\/501100004613","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["41373120"],"award-info":[{"award-number":["41373120"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Environment International"],"published-print":{"date-parts":[[2017,2]]},"DOI":"10.1016\/j.envint.2016.12.006","type":"journal-article","created":{"date-parts":[[2016,12,18]],"date-time":"2016-12-18T16:17:46Z","timestamp":1482077866000},"page":"282-292","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":59,"special_numbering":"C","title":["Environmental water chemistry and possible correlation with Kaschin-Beck Disease (KBD) in northwestern Sichuan, China"],"prefix":"10.1016","volume":"99","author":[{"given":"Zeming","family":"Shi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9704-3597","authenticated-orcid":false,"given":"Pujing","family":"Pan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanwei","family":"Feng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zezhong","family":"Kan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhonghui","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fei","family":"Wei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"3","key":"10.1016\/j.envint.2016.12.006_bb0005","first-page":"563","article-title":"Geological characteristics and etiology research on Kashin-Beck Disease in China","volume":"37","author":"An","year":"2010","journal-title":"Geol. China"},{"key":"10.1016\/j.envint.2016.12.006_bb0010","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1016\/j.joca.2007.09.002","article-title":"Articular cartilage metabolism in patients with Kashin Beck Disease: an endemic osteoarthropathy in China","volume":"16","author":"Cao","year":"2008","journal-title":"Osteoarthr. Cartil."},{"issue":"6","key":"10.1016\/j.envint.2016.12.006_bb0015","first-page":"56","article-title":"Relationship between Kashin-Beck Disease and chemical composition of water in the Baxi River Basin of Ruoergai area","volume":"10","author":"Cao","year":"2012","journal-title":"South-to-North Water Transfers and Water Science & Technology"},{"key":"10.1016\/j.envint.2016.12.006_bb0020","series-title":"Proceedings of the 8th International Working Conference on Stored Product Protection","first-page":"526","article-title":"Is Kashin-Beck Disease related to the presence of fungi on grains?","author":"Chasseur","year":"2003"},{"issue":"2","key":"10.1016\/j.envint.2016.12.006_bb0025","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1029\/TR037i002p00193","article-title":"Duty's classification of natural waters and chemical composition of atmospheric precipitation in USSR: a review","volume":"37","author":"Chilingar","year":"1956","journal-title":"Trans. Am. Geophys. Union"},{"key":"10.1016\/j.envint.2016.12.006_bb0030","series-title":"River and Stream Ecosystems of the World","author":"Cushing","year":"2006"},{"issue":"4","key":"10.1016\/j.envint.2016.12.006_bb0035","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1029\/2006TC002078","article-title":"How was the Triassic Songpan-Ganzi basin filled? A provenance study","volume":"26","author":"Enkelmann","year":"2007","journal-title":"Tectonics"},{"issue":"7","key":"10.1016\/j.envint.2016.12.006_bb0040","doi-asserted-by":"crossref","first-page":"1337","DOI":"10.1089\/ars.2010.3275","article-title":"Selenium in human health and disease","volume":"14","author":"Fairweather-Tait","year":"2011","journal-title":"Antioxid. Redox Signal."},{"key":"10.1016\/j.envint.2016.12.006_bb0045","series-title":"Essentials of Medical Geology","first-page":"373","article-title":"Selenium deficiency and toxicity in the environment","author":"Fordyce","year":"2005"},{"key":"10.1016\/j.envint.2016.12.006_bb0050","first-page":"5","article-title":"The survey of some trace elements in the Kaschin-Beck Disease-endemic areas and the microelement of zinc and copper content in the hair of Han teenagers in the Lhasa area","volume":"1","author":"Guo","year":"1991","journal-title":"The Information of Science and Technology in Tibet"},{"key":"10.1016\/j.envint.2016.12.006_bb0055","series-title":"Selenium: Chemistry, Analysis, Function and Effects (Food and Nutritional Components in Focus)","first-page":"552","article-title":"Chapter 31: selenium and Kashin\u2013Beck disease","author":"Guo","year":"2015"},{"key":"10.1016\/j.envint.2016.12.006_bb0060","first-page":"14","article-title":"A study of the relation between the whole blood selenium content of the population and Kashin-Beck disease in the low selenium regions in China","volume":"2","author":"Hou","year":"1984","journal-title":"Geogr. Res."},{"issue":"3","key":"10.1016\/j.envint.2016.12.006_bb0065","first-page":"89","article-title":"An application of the quadrature test method to studying the drinking water quality in the Kaschin-Beck Disease areas","volume":"12","author":"Hu","year":"1990","journal-title":"Journal of Xi'an College of Geology"},{"issue":"5","key":"10.1016\/j.envint.2016.12.006_bb0070","first-page":"303","article-title":"The relationship between drinking water and Kaschin-Beck Disease","volume":"11","author":"Huo","year":"1992","journal-title":"Chin. J. Endemic Prevent Cure"},{"key":"10.1016\/j.envint.2016.12.006_bb0075","series-title":"pH of Water. Fundamentals of Environmental Measurements","author":"Kemker","year":"2013"},{"key":"10.1016\/j.envint.2016.12.006_bb0080","series-title":"Trace Elements in Human and Animal Nutrition","first-page":"139","article-title":"Selenium","author":"Levander","year":"1986"},{"key":"10.1016\/j.envint.2016.12.006_bb0085","first-page":"91","article-title":"A study of Kaschin\u2013Beck Disease associated with environment selenium in Shannxi area","volume":"2","author":"Li","year":"1982","journal-title":"Acta Sci. Circumst."},{"issue":"3","key":"10.1016\/j.envint.2016.12.006_bb0090","first-page":"85","article-title":"Determination of trace elements in drinking water of Kashin\u2013Beck Disease (KBD) affected and non-affected areas in Tibet by ICP-AES","volume":"27","author":"Li","year":"2007","journal-title":"Spectrosc. Spectr. Anal."},{"key":"10.1016\/j.envint.2016.12.006_bb0095","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1007\/s11783-009-0009-4","article-title":"Soil selenium concentration and Kashin\u2013Beck disease prevalence in Tibet, China","volume":"3","author":"Li","year":"2009","journal-title":"Front. Environ. Sci. Eng. China"},{"key":"10.1016\/j.envint.2016.12.006_bb0100","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/j.scitotenv.2011.02.040","article-title":"Medical geology of arsenic, selenium and thallium in China","volume":"421\u2013422","author":"Li","year":"2012","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.envint.2016.12.006_bb0105","series-title":"River Ecosystem Ecology: A Global Perspective","author":"Likens","year":"2010"},{"key":"10.1016\/j.envint.2016.12.006_bb0110","first-page":"81","article-title":"The correlation analysis between the Kashin-Beck disease and the factors of the geological environment","volume":"1","author":"Lin","year":"1983","journal-title":"J. Changchun University of Earth Sciences"},{"key":"10.1016\/j.envint.2016.12.006_bb0115","series-title":"Hydrogeochemical Features and Disease-related Analysis in Kaschin-Beck Disease Area, Zamtang County, Northwest Sichuan Plateau","author":"Liu","year":"2011"},{"issue":"3","key":"10.1016\/j.envint.2016.12.006_bb0120","first-page":"571","article-title":"Chemical composition of water environment in Kaschin-Beck Disease areas of China: a summary","volume":"37","author":"Liu","year":"2010","journal-title":"Geol. China"},{"issue":"2","key":"10.1016\/j.envint.2016.12.006_bb0125","first-page":"83","article-title":"The research progression on the relationship of selenium, iodine, fluorine and Kashin Beck disease","volume":"33","author":"Liu","year":"2012","journal-title":"Foreign Medical Science Section of Medgeography"},{"key":"10.1016\/j.envint.2016.12.006_bb0130","first-page":"70","article-title":"Big Bone Disease. A multidisciplinary approach of KBD in Tibet Autonomous Region (P.R. China)","volume":"15","author":"Malaisse","year":"2008","journal-title":"Les Presses Agronomiques de Gembloux, ASBL (Belgium)"},{"key":"10.1016\/j.envint.2016.12.006_bb0135","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1007\/s002640000190","article-title":"Histology of Kashin-Beck lesions","volume":"25","author":"Pasteels","year":"2001","journal-title":"Int. Orthop."},{"key":"10.1016\/j.envint.2016.12.006_bb0140","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1289\/ehp.99107293","article-title":"The role of humic substances in drinking water in Kashin\u2013Beck disease in China","volume":"107","author":"Peng","year":"1999","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.envint.2016.12.006_bb0145","doi-asserted-by":"crossref","first-page":"914","DOI":"10.1029\/TR025i006p00914","article-title":"A graphic procedure in the geochemical interpretation of water-analyses","volume":"25","author":"Piper","year":"1944","journal-title":"Am. Geoph. Union Trans."},{"key":"10.1016\/j.envint.2016.12.006_bb0150","series-title":"USGS Ground Water Note No. 12","article-title":"A graphic procedure in the geochemical interpretation of water-analyses","author":"Piper","year":"1953"},{"issue":"2","key":"10.1016\/j.envint.2016.12.006_bb0155","first-page":"80","article-title":"Analysis of the relationship between contents of 21 elements in external environment and active index using samples from Kashin-beck disease affected areas","volume":"7","author":"Sa","year":"1992","journal-title":"Endemic Diseases Bulle."},{"key":"10.1016\/j.envint.2016.12.006_bb0160","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1007\/s00264-010-1043-3","article-title":"Kashin Beck Disease: more than just osteoarthrosis A cross-sectional study regarding the influence of body function-structures and activities on level of participation","volume":"35","author":"Schepman","year":"2011","journal-title":"Int. Orthop."},{"key":"10.1016\/j.envint.2016.12.006_bb0165","first-page":"343","article-title":"The history of Kashin-Beck disease","volume":"89","author":"Sokoloff","year":"1989","journal-title":"N.Y. State J. Med."},{"issue":"10","key":"10.1016\/j.envint.2016.12.006_bb0170","doi-asserted-by":"crossref","first-page":"15","DOI":"10.2118\/951376-G","article-title":"The interpretation of chemical water analysis by means of patterns","volume":"3","author":"Stiff","year":"1951","journal-title":"J. Pet. Technol."},{"key":"10.1016\/j.envint.2016.12.006_bb0175","doi-asserted-by":"crossref","first-page":"1378","DOI":"10.1126\/science.324_1378","article-title":"A medical mystery in middle China","volume":"324","author":"Stone","year":"2009","journal-title":"Science"},{"key":"10.1016\/j.envint.2016.12.006_bb0180","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1007\/s002640100247","article-title":"Epidemiological support for a multifactorial aetiology of Kashin-Beck disease in Tibet","volume":"25","author":"Suetens","year":"2001","journal-title":"Int. Orthop."},{"issue":"1\u20133","key":"10.1016\/j.envint.2016.12.006_bb0185","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1007\/s12011-012-9469-7","article-title":"T-2 toxin contamination in grains and selenium concentration in drinking water and grains in Kaschin-Beck Disease endemic areas of Qinghai Province","volume":"150","author":"Sun","year":"2012","journal-title":"Biol. Trace Elem. Res."},{"issue":"1","key":"10.1016\/j.envint.2016.12.006_bb0190","first-page":"132","article-title":"A study of the relationship between hydrochemistry and Kaschin-Beck Disease in the Zequ river basin","volume":"39","author":"Sun","year":"2012","journal-title":"Hydrogeology & Engineering Geology"},{"key":"10.1016\/j.envint.2016.12.006_bb0195","series-title":"The Atlas of Endemic Diseases and Their Environments in the People's Republic of China","year":"1989"},{"issue":"18","key":"10.1016\/j.envint.2016.12.006_bb0200","first-page":"161","article-title":"A historic overview of research and control on Kashin-Beck Disease in China","volume":"3","author":"Wang","year":"1999","journal-title":"Chinese J. Endemiology"},{"issue":"12","key":"10.1016\/j.envint.2016.12.006_bb0205","first-page":"29","article-title":"Environmental trace elements and Kchin-Beck Disease","volume":"4","author":"Wang","year":"1997","journal-title":"Guangdong Microelement Science"},{"issue":"1","key":"10.1016\/j.envint.2016.12.006_bb0210","first-page":"48","article-title":"The environmental hydrogeology of KBD district in Rangtang County of Aba","volume":"20","author":"Wang","year":"2006","journal-title":"Resources Environment & Engineering"},{"issue":"4","key":"10.1016\/j.envint.2016.12.006_bb0215","first-page":"15","article-title":"Role of interaction between selenium and organic matters on causes of Kaschin-Beck Disease","volume":"3","author":"Wang","year":"1991","journal-title":"J. Environ. Sci. (China)"},{"issue":"1","key":"10.1016\/j.envint.2016.12.006_bb0220","first-page":"70","article-title":"The relations of Kashin-Beck Disease to hydrochemical components and the pathogeny in Yongshou County, Shaanxi","volume":"4","author":"Xiao","year":"1986","journal-title":"Geology of Shaanxi"},{"issue":"4","key":"10.1016\/j.envint.2016.12.006_bb0225","first-page":"36","article-title":"Study on the relations between Kashin-Beck Disease and iodine","volume":"14","author":"Xu","year":"1999","journal-title":"Endemic Disease Bull."},{"issue":"11\u221212","key":"10.1016\/j.envint.2016.12.006_bb0230","doi-asserted-by":"crossref","first-page":"1095","DOI":"10.1016\/j.nut.2011.03.002","article-title":"Selenium, iodine, and the relation with Kashin-Beck Disease","volume":"27","author":"Yao","year":"2011","journal-title":"Nutrition"},{"issue":"2","key":"10.1016\/j.envint.2016.12.006_bb0235","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1111\/j.1745-6584.1972.tb02912.x","article-title":"Graphical interpretation of water-quality data","volume":"10","author":"Zaporozec","year":"1972","journal-title":"Ground Water"},{"issue":"14","key":"10.1016\/j.envint.2016.12.006_bb0240","first-page":"72","article-title":"The epidemic characteristics of Kaschin-Beck Disease (KBD) in different eco-environments","volume":"1991","author":"Zhai","year":"1991","journal-title":"J. Environ. Sci."},{"key":"10.1016\/j.envint.2016.12.006_bb0245","series-title":"Quality Assurance Manual for Environmental Water Monitoring","year":"1994"},{"issue":"2","key":"10.1016\/j.envint.2016.12.006_bb0250","first-page":"67","article-title":"Geochemical characteristics of the river system in east China","volume":"9","author":"Zhang","year":"1990","journal-title":"Geogr. Res."},{"issue":"3","key":"10.1016\/j.envint.2016.12.006_bb0255","first-page":"220","article-title":"The geochemical characteristics of the water in the Changjiang River system","volume":"47","author":"Zhang","year":"1992","journal-title":"Acta Geograph. Sin."},{"issue":"3","key":"10.1016\/j.envint.2016.12.006_bb0260","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1007\/s002640100242","article-title":"Selenium, iodine and fungal contamination in Yulin District (People's Republic of China) endemic for Kashin-Beck disease","volume":"25","author":"Zhang","year":"2001","journal-title":"Int. Orthop."},{"issue":"6","key":"10.1016\/j.envint.2016.12.006_bb0265","first-page":"886","article-title":"Selenium in environment and its relationship with Kaschin-Beck Disease in Rangtang County, Sichuan Province","volume":"28","author":"Zhang","year":"2009","journal-title":"Prog. Geogr."},{"key":"10.1016\/j.envint.2016.12.006_bb0270","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1016\/j.joca.2008.06.011","article-title":"Selenium for preventing Kashin\u2013Beck osteoarthropathy in children: a meta-analysis","volume":"17","author":"Zou","year":"2009","journal-title":"Osteoarthr. Cartil."}],"container-title":["Environment International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0160412016309874?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0160412016309874?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,3,11]],"date-time":"2021-03-11T06:45:27Z","timestamp":1615445127000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0160412016309874"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,2]]},"references-count":54,"alternative-id":["S0160412016309874"],"URL":"https:\/\/doi.org\/10.1016\/j.envint.2016.12.006","relation":{},"ISSN":["0160-4120"],"issn-type":[{"value":"0160-4120","type":"print"}],"subject":[],"published":{"date-parts":[[2017,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Environmental water chemistry and possible correlation with Kaschin-Beck Disease (KBD) in northwestern Sichuan, China","name":"articletitle","label":"Article Title"},{"value":"Environment International","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.envint.2016.12.006","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}