{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,26]],"date-time":"2026-10-26T01:04:41Z","timestamp":1792976681084,"version":"4.5.0"},"reference-count":72,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2018,4,1]],"date-time":"2018-04-01T00:00:00Z","timestamp":1522540800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01 CA133595"],"award-info":[{"award-number":["R01 CA133595"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01 ES017875"],"award-info":[{"award-number":["R01 ES017875"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["P42 ES10349"],"award-info":[{"award-number":["P42 ES10349"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["P30 ES009089"],"award-info":[{"award-number":["P30 ES009089"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["T32 CA009529-24"],"award-info":[{"award-number":["T32 CA009529-24"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Environment International"],"published-print":{"date-parts":[[2018,4]]},"DOI":"10.1016\/j.envint.2018.01.015","type":"journal-article","created":{"date-parts":[[2018,2,6]],"date-time":"2018-02-06T03:40:43Z","timestamp":1517888443000},"page":"133-142","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":31,"special_numbering":"C","title":["Serum homocysteine, arsenic methylation, and arsenic-induced skin lesion incidence in Bangladesh: A one-carbon metabolism candidate gene study"],"prefix":"10.1016","volume":"113","author":[{"given":"Megan M.","family":"Niedzwiecki","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8539-7438","authenticated-orcid":false,"given":"Xinhua","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huiping","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Megan N.","family":"Hall","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vesna","family":"Slavkovich","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vesna","family":"Ilievski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Diane","family":"Levy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abu B.","family":"Siddique","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muhammad G.","family":"Kibriya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Faruque","family":"Parvez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tariqul","family":"Islam","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alauddin","family":"Ahmed","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana","family":"Navas-Acien","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph H.","family":"Graziano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard H.","family":"Finnell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Habibul","family":"Ahsan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mary V.","family":"Gamble","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.envint.2018.01.015_bb0005","doi-asserted-by":"crossref","first-page":"1195","DOI":"10.1097\/00043764-200012000-00016","article-title":"Associations between drinking water and urinary arsenic levels and skin lesions in Bangladesh","volume":"42","author":"Ahsan","year":"2000","journal-title":"J. Occup. Environ. Med."},{"key":"10.1016\/j.envint.2018.01.015_bb0010","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1038\/sj.jea.7500449","article-title":"Health effects of arsenic longitudinal study (heals): description of a multidisciplinary epidemiologic investigation","volume":"16","author":"Ahsan","year":"2006","journal-title":"J. Expo. Sci. Environ. Epidemiol."},{"key":"10.1016\/j.envint.2018.01.015_bb0015","doi-asserted-by":"crossref","first-page":"1138","DOI":"10.1093\/aje\/kwj154","article-title":"Arsenic exposure from drinking water and risk of premalignant skin lesions in Bangladesh: baseline results from the health effects of arsenic longitudinal study","volume":"163","author":"Ahsan","year":"2006","journal-title":"Am. J. Epidemiol."},{"key":"10.1016\/j.envint.2018.01.015_bb0020","series-title":"Cancer Epidemiology, Biomarkers & Prevention: A Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology","first-page":"1270","article-title":"Arsenic metabolism, genetic susceptibility, and risk of premalignant skin lesions in Bangladesh","volume":"16","author":"Ahsan","year":"2007"},{"key":"10.1016\/j.envint.2018.01.015_bb0025","doi-asserted-by":"crossref","first-page":"281","DOI":"10.3988\/jcn.2014.10.4.281","article-title":"Hyperhomocysteinemia and neurologic disorders: a review","volume":"10","author":"Ansari","year":"2014","journal-title":"J. Clin. Neurol. (Seoul, Korea)"},{"key":"10.1016\/j.envint.2018.01.015_bb0030","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1016\/S0140-6736(10)60481-3","article-title":"Arsenic exposure from drinking water, and all-cause and chronic-disease mortalities in Bangladesh (heals): a prospective cohort study","volume":"376","author":"Argos","year":"2010","journal-title":"Lancet (London, England)"},{"key":"10.1016\/j.envint.2018.01.015_bb0035","first-page":"43","article-title":"Genetic variation in glutathione s-transferase omega-1, arsenic methyltransferase and methylene-tetrahydrofolate reductase, arsenic exposure and bladder cancer: a case-control study","volume":"11","author":"Beebe-Dimmer","year":"2012","journal-title":"Environ. Health Glob. Access Sci. Source"},{"key":"10.1016\/j.envint.2018.01.015_bb0040","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1111\/j.2517-6161.1995.tb02031.x","article-title":"Controlling the false discovery rate: a practical and powerful approach to multiple testing","volume":"57","author":"Benjamini","year":"1995","journal-title":"J. R. Stat. Soc. Ser. B Methodol."},{"key":"10.1016\/j.envint.2018.01.015_bb0045","doi-asserted-by":"crossref","first-page":"3290","DOI":"10.1073\/pnas.94.7.3290","article-title":"Folate deficiency causes uracil misincorporation into human DNA and chromosome breakage: implications for cancer and neuronal damage","volume":"94","author":"Blount","year":"1997","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.envint.2018.01.015_bb0050","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1016\/0006-291X(83)91536-X","article-title":"Coordinate inhibition of DNA synthesis and thymidylate synthase activity following DNA damage and repair","volume":"117","author":"Boorstein","year":"1983","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.envint.2018.01.015_bb0055","doi-asserted-by":"crossref","first-page":"39","DOI":"10.3945\/ajcn.115.116038","article-title":"Is there a causal role for homocysteine concentration in blood pressure? A mendelian randomization study","volume":"103","author":"Borges","year":"2016","journal-title":"Am. J. Clin. Nutr."},{"key":"10.1016\/j.envint.2018.01.015_bb0060","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1093\/ajcn\/72.2.315","article-title":"Homocysteine and cardiovascular disease: cause or effect?","volume":"72","author":"Brattstrom","year":"2000","journal-title":"Am. J. Clin. Nutr."},{"key":"10.1016\/j.envint.2018.01.015_bb0065","doi-asserted-by":"crossref","first-page":"721","DOI":"10.1146\/annurev.bi.64.070195.003445","article-title":"The catalytic mechanism and structure of thymidylate synthase","volume":"64","author":"Carreras","year":"1995","journal-title":"Annu. Rev. Biochem."},{"key":"10.1016\/j.envint.2018.01.015_bb0070","doi-asserted-by":"crossref","first-page":"1089","DOI":"10.1210\/jc.2002-021133","article-title":"Hyperhomocysteinemia in Asian Indians living in the United States","volume":"88","author":"Chandalia","year":"2003","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.envint.2018.01.015_bb0075","doi-asserted-by":"crossref","first-page":"1605","DOI":"10.1007\/s10552-010-9589-3","article-title":"Polymorphisms in one-carbon metabolism pathway genes, urinary arsenic profile, and urothelial carcinoma","volume":"21","author":"Chung","year":"2010","journal-title":"Cancer Causes Control: CCC"},{"key":"10.1016\/j.envint.2018.01.015_bb0080","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pmed.1001177","article-title":"Homocysteine and coronary heart disease: meta-analysis of mthfr case-control studies, avoiding publication bias","volume":"9","author":"Clarke","year":"2012","journal-title":"PLoS Med."},{"key":"10.1016\/j.envint.2018.01.015_bb0085","doi-asserted-by":"crossref","first-page":"1","DOI":"10.18637\/jss.v034.i02","article-title":"Beta regression in R.","volume":"34","author":"Cribari-Neto","year":"2010","journal-title":"J. Stat. Softw."},{"key":"10.1016\/j.envint.2018.01.015_bb0090","doi-asserted-by":"crossref","first-page":"1957","DOI":"10.1161\/01.STR.0000131749.81508.18","article-title":"Cerebral vascular dysfunction mediated by superoxide in hyperhomocysteinemic mice","volume":"35","author":"Dayal","year":"2004","journal-title":"Stroke"},{"key":"10.1016\/j.envint.2018.01.015_bb0095","first-page":"149","article-title":"Relationship between 5,10-methylenetetrahydrofolate reductase genetic polymorphism and arsenic metabolism","volume":"39","author":"Deng","year":"2007","journal-title":"Beijing da xue xue bao Yi xue ban\u202f=\u202fJ. Peking Univ. Health Sci."},{"key":"10.1016\/j.envint.2018.01.015_bb0100","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1172\/JCI8342","article-title":"Endothelial dysfunction in a murine model of mild hyperhomocyst(e)inemia","volume":"106","author":"Eberhardt","year":"2000","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.envint.2018.01.015_bb0105","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1289\/ehp.1002471","article-title":"Polymorphisms in arsenic(+iii oxidation state) methyltransferase (as3mt) predict gene expression of as3mt as well as arsenic metabolism","volume":"119","author":"Engstrom","year":"2011","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.envint.2018.01.015_bb0110","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/j.taap.2015.07.017","article-title":"Gene-arsenic interaction in longitudinal changes of blood pressure: findings from the health effects of arsenic longitudinal study (heals) in Bangladesh","volume":"288","author":"Farzan","year":"2015","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"10.1016\/j.envint.2018.01.015_bb0115","doi-asserted-by":"crossref","first-page":"799","DOI":"10.1080\/0266476042000214501","article-title":"Beta regression for modelling rates and proportions","volume":"31","author":"Ferrari","year":"2004","journal-title":"J. Appl. Stat."},{"key":"10.1016\/j.envint.2018.01.015_bb0120","doi-asserted-by":"crossref","first-page":"1372","DOI":"10.1093\/ajcn\/81.6.1372","article-title":"Folate and cobalamin deficiencies and hyperhomocysteinemia in Bangladesh","volume":"81","author":"Gamble","year":"2005","journal-title":"Am. J. Clin. Nutr."},{"key":"10.1016\/j.envint.2018.01.015_bb0125","doi-asserted-by":"crossref","first-page":"1093","DOI":"10.1093\/ajcn\/84.5.1093","article-title":"Folate and arsenic metabolism: a double-blind, placebo-controlled folic acid-supplementation trial in Bangladesh","volume":"84","author":"Gamble","year":"2006","journal-title":"Am. J. Clin. Nutr."},{"key":"10.1016\/j.envint.2018.01.015_bb0130","doi-asserted-by":"crossref","first-page":"1202","DOI":"10.1093\/ajcn\/86.4.1202","article-title":"Folic acid supplementation lowers blood arsenic","volume":"86","author":"Gamble","year":"2007","journal-title":"Am. J. Clin. Nutr."},{"key":"10.1016\/j.envint.2018.01.015_bb0135","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1016\/j.etap.2017.08.032","article-title":"Genetic susceptibility to breast cancer risk associated with inorganic arsenic exposure","volume":"56","author":"Gamboa-Loira","year":"2017","journal-title":"Environ. Toxicol. Pharmacol."},{"key":"10.1016\/j.envint.2018.01.015_bb0140","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1186\/1475-2891-14-6","article-title":"Role of homocysteine in the development of cardiovascular disease","volume":"14","author":"Ganguly","year":"2015","journal-title":"Nutr. J."},{"key":"10.1016\/j.envint.2018.01.015_bb0145","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1016\/S0021-9150(00)00739-5","article-title":"The methionine synthase reductase (mtrr) a66g polymorphism is a novel genetic determinant of plasma homocysteine concentrations","volume":"157","author":"Gaughan","year":"2001","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.envint.2018.01.015_bb0150","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1186\/1475-2891-11-45","article-title":"Associations between toenail arsenic concentration and dietary factors in a New Hampshire population","volume":"11","author":"Gruber","year":"2012","journal-title":"Nutr. J."},{"key":"10.1016\/j.envint.2018.01.015_bb0155","doi-asserted-by":"crossref","first-page":"1724","DOI":"10.1289\/ehp.0900734","article-title":"Influence of cobalamin on arsenic metabolism in Bangladesh","volume":"117","author":"Hall","year":"2009","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.envint.2018.01.015_bb0160","doi-asserted-by":"crossref","first-page":"38381","DOI":"10.1074\/jbc.M205000200","article-title":"Cytoplasmic serine hydroxymethyltransferase mediates competition between folate-dependent deoxyribonucleotide ands-adenosylmethionine biosyntheses","volume":"277","author":"Herbig","year":"2002","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.envint.2018.01.015_bb0165","doi-asserted-by":"crossref","first-page":"690","DOI":"10.3945\/jn.113.188789","article-title":"Folate and cobalamin modify associations between s-adenosylmethionine and methylated arsenic metabolites in arsenic-exposed Bangladeshi adults","volume":"144","author":"Howe","year":"2014","journal-title":"J. Nutr."},{"key":"10.1016\/j.envint.2018.01.015_bb0170","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1161\/01.CIR.93.1.7","article-title":"Relation between folate status, a common mutation in methylenetetrahydrofolate reductase, and plasma homocysteine concentrations","volume":"93","author":"Jacques","year":"1996","journal-title":"Circulation"},{"key":"10.1016\/j.envint.2018.01.015_bb0175","first-page":"1407","article-title":"Thymidylate synthase gene and protein expression correlate and are associated with response to 5-fluorouracil in human colorectal and gastric tumors","volume":"55","author":"Johnston","year":"1995","journal-title":"Cancer Res."},{"key":"10.1016\/j.envint.2018.01.015_bb0180","doi-asserted-by":"crossref","first-page":"E2319","DOI":"10.1073\/pnas.1619745114","article-title":"Arsenic trioxide targets mthfd1 and sumo-dependent nuclear de novo thymidylate biosynthesis","volume":"114","author":"Kamynina","year":"2017","journal-title":"Proc. Natl. Acad. Sci."},{"key":"10.1016\/j.envint.2018.01.015_bb0185","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1016\/j.ijheh.2005.04.005","article-title":"Methylenetetrahydrofolate reductase (mthfr) variants and bladder cancer: a population-based case-control study","volume":"208","author":"Karagas","year":"2005","journal-title":"Int. J. Hyg. Environ. Health"},{"key":"10.1016\/j.envint.2018.01.015_bb0190","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1007\/s40572-014-0040-x","article-title":"Drinking water arsenic contamination, skin lesions, and malignancies: a systematic review of the global evidence","volume":"2","author":"Karagas","year":"2015","journal-title":"Curr. Environ. Health Rep."},{"key":"10.1016\/j.envint.2018.01.015_bb0195","doi-asserted-by":"crossref","first-page":"10795","DOI":"10.1074\/jbc.M110246200","article-title":"A novel s-adenosyl-l-methionine: arsenic(iii) methyltransferase from rat liver cytosol","volume":"277","author":"Lin","year":"2002","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.envint.2018.01.015_bb0200","doi-asserted-by":"crossref","first-page":"1081","DOI":"10.1289\/ehp.10026","article-title":"Metabolism of low-dose inorganic arsenic in a central European population: influence of sex and genetic polymorphisms","volume":"115","author":"Lindberg","year":"2007","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.envint.2018.01.015_bb0205","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pgen.1003640","article-title":"Oxidative stress and replication-independent DNA breakage induced by arsenic in saccharomyces cerevisiae","volume":"9","author":"Litwin","year":"2013","journal-title":"PLoS Genet."},{"key":"10.1016\/j.envint.2018.01.015_bb0210","doi-asserted-by":"crossref","first-page":"572","DOI":"10.1038\/nrc3557","article-title":"Serine, glycine and the one-carbon cycle: cancer metabolism in full circle","volume":"13","author":"Locasale","year":"2013","journal-title":"Nat. Rev. Cancer"},{"key":"10.1016\/j.envint.2018.01.015_bb0215","first-page":"1098","article-title":"Methylenetetrahydrofolate reductase polymorphism, dietary interactions, and risk of colorectal cancer","volume":"57","author":"Ma","year":"1997","journal-title":"Cancer Res."},{"key":"10.1016\/j.envint.2018.01.015_bb0220","doi-asserted-by":"crossref","first-page":"754","DOI":"10.1002\/bdra.23399","article-title":"Polymorphisms in maternal folate pathway genes interact with arsenic in drinking water to influence risk of myelomeningocele","volume":"103","author":"Mazumdar","year":"2015","journal-title":"Birth Defects Res. A Clin. Mol. Teratol."},{"key":"10.1016\/j.envint.2018.01.015_bb0225","doi-asserted-by":"crossref","first-page":"542","DOI":"10.1007\/s11883-012-0280-x","article-title":"Arsenic exposure and cardiovascular disease: an updated systematic review","volume":"14","author":"Moon","year":"2012","journal-title":"Curr Atheroscler Rep"},{"key":"10.1016\/j.envint.2018.01.015_bb0230","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1007\/s10552-006-0057-z","article-title":"Trace elements and cancer risk: a review of the epidemiologic evidence","volume":"18","author":"Navarro Silvera","year":"2007","journal-title":"Cancer Causes Control: CCC"},{"key":"10.1016\/j.envint.2018.01.015_bb0235","doi-asserted-by":"crossref","first-page":"1575","DOI":"10.1093\/clinchem\/37.9.1575","article-title":"Total arsenic in urine: palladium-persulfate vs nickel as a matrix modifier for graphite furnace atomic absorption spectrophotometry","volume":"37","author":"Nixon","year":"1991","journal-title":"Clin. Chem."},{"key":"10.1016\/j.envint.2018.01.015_bb0240","doi-asserted-by":"crossref","first-page":"1294","DOI":"10.1289\/ehp.1409396","article-title":"Folic acid and creatine as therapeutic approaches to lower blood arsenic: a randomized controlled trial","volume":"123","author":"Peters","year":"2015","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.envint.2018.01.015_bb0245","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1093\/clinchem\/45.2.290","article-title":"Rapid and accurate HPLC assay for plasma total homocysteine and cysteine in a clinical laboratory setting","volume":"45","author":"Pfeiffer","year":"1999","journal-title":"Clin. Chem."},{"key":"10.1016\/j.envint.2018.01.015_bb0250","doi-asserted-by":"crossref","first-page":"1862","DOI":"10.1093\/ije\/dyt182","article-title":"Arsenic metabolism efficiency has a causal role in arsenic toxicity: Mendelian randomization and gene-environment interaction","volume":"42","author":"Pierce","year":"2013","journal-title":"Int. J. Epidemiol."},{"key":"10.1016\/j.envint.2018.01.015_bb0255","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1289\/ehp.11872","article-title":"Folate deficiency, hyperhomocysteinemia, low urinary creatinine, and hypomethylation of leukocyte DNA are risk factors for arsenic-induced skin lesions","volume":"117","author":"Pilsner","year":"2009","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.envint.2018.01.015_bb0260","doi-asserted-by":"crossref","first-page":"580","DOI":"10.1016\/j.envres.2010.05.001","article-title":"Association of genetic variation in cystathionine-beta-synthase and arsenic metabolism","volume":"110","author":"Porter","year":"2010","journal-title":"Environ. Res."},{"key":"10.1016\/j.envint.2018.01.015_bb0265","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1016\/0002-9343(94)90149-X","article-title":"Sensitivity of serum methylmalonic acid and total homocysteine determinations for diagnosing cobalamin and folate deficiencies","volume":"96","author":"Savage","year":"1994","journal-title":"Am. J. Med."},{"key":"10.1016\/j.envint.2018.01.015_bb0270","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1289\/ehp.9734","article-title":"Genetic polymorphisms influencing arsenic metabolism: evidence from Argentina","volume":"115","author":"Schl\u00e4wicke Engstr\u00f6m","year":"2007","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.envint.2018.01.015_bb0275","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1016\/j.mrfmmm.2008.07.003","article-title":"Arsenic metabolism is influenced by polymorphisms in genes involved in one-carbon metabolism and reduction reactions","volume":"667","author":"Schlawicke Engstrom","year":"2009","journal-title":"Mutat. Res."},{"key":"10.1016\/j.envint.2018.01.015_bb0280","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1097\/00043798-199808000-00003","article-title":"Folic acid, homocysteine and one-carbon metabolism: a review of the essential biochemistry","volume":"5","author":"Scott","year":"1998","journal-title":"J. Cardiovasc. Risk"},{"key":"10.1016\/j.envint.2018.01.015_bb0285","doi-asserted-by":"crossref","first-page":"730","DOI":"10.1002\/clc.4960241108","article-title":"Possible ethnic differences in plasma homocysteine levels associated with coronary artery disease between south Asian and east Asian immigrants","volume":"24","author":"Senaratne","year":"2001","journal-title":"Clin. Cardiol."},{"key":"10.1016\/j.envint.2018.01.015_bb0290","doi-asserted-by":"crossref","first-page":"2222","DOI":"10.1002\/cncr.29291","article-title":"A distinct and replicable variant of the squamous cell carcinoma gene inositol polyphosphate-5-phosphatase modifies the susceptibility of arsenic-associated skin lesions in Bangladesh","volume":"121","author":"Seow","year":"2015","journal-title":"Cancer"},{"key":"10.1016\/j.envint.2018.01.015_bb0295","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1093\/nar\/29.1.308","article-title":"Dbsnp: the ncbi database of genetic variation","volume":"29","author":"Sherry","year":"2001","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.envint.2018.01.015_bb0300","doi-asserted-by":"crossref","first-page":"381","DOI":"10.3109\/00365516509077065","article-title":"Plasma creatinine determination. A new and specific Jaffe reaction method","volume":"17","author":"Slot","year":"1965","journal-title":"Scand. J. Clin. Lab. Invest."},{"key":"10.1016\/j.envint.2018.01.015_bb0305","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1080\/15287390600755240","article-title":"Genetic polymorphisms in MTHFR 677 and 1298, GSTM1 and t1, and metabolism of arsenic","volume":"70","author":"Steinmaus","year":"2007","journal-title":"J. Toxic. Environ. Health A"},{"key":"10.1016\/j.envint.2018.01.015_bb0310","series-title":"Rstudio: Integrated Development for r","author":"Team","year":"2015"},{"key":"10.1016\/j.envint.2018.01.015_bb0315","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1038\/nature15393","article-title":"A global reference for human genetic variation","volume":"526","author":"The Genomes Project C","year":"2015","journal-title":"Nature"},{"key":"10.1016\/j.envint.2018.01.015_bb0320","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1007\/s40572-014-0012-1","article-title":"The effects of arsenic exposure on neurological and cognitive dysfunction in human and rodent studies: a review","volume":"1","author":"Tyler","year":"2014","journal-title":"Curr. Environ. Health Rep."},{"key":"10.1016\/j.envint.2018.01.015_bb0325","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1021\/es0491073","article-title":"Reliability of a commercial kit to test groundwater for arsenic in Bangladesh","volume":"39","author":"Van Geen","year":"2005","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.envint.2018.01.015_bb0330","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1093\/ajcn\/73.3.499","article-title":"Population determinants of homocysteine","volume":"73","author":"Vollset","year":"2001","journal-title":"Am. J. Clin. Nutr."},{"key":"10.1016\/j.envint.2018.01.015_bb0335","doi-asserted-by":"crossref","first-page":"1202","DOI":"10.1136\/bmj.325.7374.1202","article-title":"Homocysteine and cardiovascular disease: evidence on causality from a meta-analysis","volume":"325","author":"Wald","year":"2002","journal-title":"BMJ (Clin. Res. Ed)"},{"key":"10.1016\/j.envint.2018.01.015_bb0340","doi-asserted-by":"crossref","first-page":"1488","DOI":"10.1373\/clinchem.2012.191791","article-title":"Homocysteine as a cause of ischemic heart disease: the door remains open","volume":"58","author":"Wald","year":"2012","journal-title":"Clin. Chem."},{"key":"10.1016\/j.envint.2018.01.015_bb0345","series-title":"Genetics: Population Genetics. R package version 1.3.8.1","author":"Warnes","year":"2013"},{"key":"10.1016\/j.envint.2018.01.015_bb0350","doi-asserted-by":"crossref","first-page":"17623","DOI":"10.1074\/jbc.M702526200","article-title":"Evidence for small ubiquitin-like modifier-dependent nuclear import of the thymidylate biosynthesis pathway","volume":"282","author":"Woeller","year":"2007","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.envint.2018.01.015_bb0355","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/S0009-8981(02)00174-2","article-title":"Hyperhomocysteinemia is a risk factor for cancer and a new potential tumor marker","volume":"322","author":"Wu","year":"2002","journal-title":"Clin. Chim. Acta Int. J. Clin. Chem."},{"key":"10.1016\/j.envint.2018.01.015_bb0360","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/j.apgeochem.2003.09.007","article-title":"Redox control of arsenic mobilization in Bangladesh groundwater","volume":"19","author":"Zheng","year":"2004","journal-title":"Appl. Geochem."}],"container-title":["Environment International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0160412017317397?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0160412017317397?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:09:50Z","timestamp":1719792590000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0160412017317397"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,4]]},"references-count":72,"alternative-id":["S0160412017317397"],"URL":"https:\/\/doi.org\/10.1016\/j.envint.2018.01.015","relation":{},"ISSN":["0160-4120"],"issn-type":[{"value":"0160-4120","type":"print"}],"subject":[],"published":{"date-parts":[[2018,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Serum homocysteine, arsenic methylation, and arsenic-induced skin lesion incidence in Bangladesh: A one-carbon metabolism candidate gene study","name":"articletitle","label":"Article Title"},{"value":"Environment International","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.envint.2018.01.015","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}