{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T17:39:20Z","timestamp":1792172360368,"version":"4.4.0"},"reference-count":50,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2018,10,1]],"date-time":"2018-10-01T00:00:00Z","timestamp":1538352000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,10,1]],"date-time":"2018-10-01T00:00:00Z","timestamp":1538352000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100001321","name":"National Research Foundation","doi-asserted-by":"publisher","award":["NRF-2017R1D1A1B03029342"],"award-info":[{"award-number":["NRF-2017R1D1A1B03029342"]}],"id":[{"id":"10.13039\/501100001321","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001321","name":"National Research Foundation","doi-asserted-by":"publisher","award":["NRF2018R1C1B6001708"],"award-info":[{"award-number":["NRF2018R1C1B6001708"]}],"id":[{"id":"10.13039\/501100001321","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002701","name":"Ministry of Education","doi-asserted-by":"publisher","award":["NRF-2018R1D1A1B07049034"],"award-info":[{"award-number":["NRF-2018R1D1A1B07049034"]}],"id":[{"id":"10.13039\/501100002701","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Ministry of Science and ICT","award":["K21004000001-10A0500-00710"],"award-info":[{"award-number":["K21004000001-10A0500-00710"]}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Environment International"],"published-print":{"date-parts":[[2018,10]]},"DOI":"10.1016\/j.envint.2018.06.041","type":"journal-article","created":{"date-parts":[[2018,7,5]],"date-time":"2018-07-05T17:23:37Z","timestamp":1530811417000},"page":"264-273","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":81,"special_numbering":"C","title":["Short- and long-term exposure to ambient air pollution and circulating biomarkers of inflammation in non-smokers: A hospital-based cohort study in South Korea"],"prefix":"10.1016","volume":"119","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6041-0840","authenticated-orcid":false,"given":"Hyewon","family":"Lee","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Woojae","family":"Myung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Byeong-Ho","family":"Jeong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hong","family":"Choi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Byung Woo","family":"Jhun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7472-3752","authenticated-orcid":false,"given":"Ho","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.envint.2018.06.041_bb0005","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1183\/09031936.00130014","article-title":"Adult lung function and long-term air pollution exposure. Escape: a multicentre cohort study and meta-analysis","volume":"45","author":"Adam","year":"2015","journal-title":"Eur. Respir. J."},{"issue":"10","key":"10.1016\/j.envint.2018.06.041_bb0010","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1136\/oem.55.10.651","article-title":"Effect of measurement error on epidemiological studies of environmental and occupational exposures","volume":"55","author":"Armstrong","year":"1998","journal-title":"Occup. Environ. Med."},{"issue":"2","key":"10.1016\/j.envint.2018.06.041_bb0015","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1111\/j.1538-7836.2007.02300.x","article-title":"Effects of exposure to air pollution on blood coagulation","volume":"5","author":"Baccarelli","year":"2007","journal-title":"J. Thromb. Haemost."},{"issue":"4","key":"10.1016\/j.envint.2018.06.041_bb0020","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1016\/j.crohns.2011.02.017","article-title":"Air pollution: an environmental factor contributing to intestinal disease","volume":"5","author":"Beamish","year":"2011","journal-title":"J. Crohn's Colitis"},{"issue":"19","key":"10.1016\/j.envint.2018.06.041_bb0025","doi-asserted-by":"crossref","first-page":"2372","DOI":"10.1001\/jama.292.19.2372","article-title":"Ozone and short-term mortality in 95 us urban communities, 1987-2000","volume":"292","author":"Bell","year":"2004","journal-title":"JAMA"},{"issue":"21","key":"10.1016\/j.envint.2018.06.041_bb0030","doi-asserted-by":"crossref","first-page":"2655","DOI":"10.1161\/01.CIR.0000128587.30041.C8","article-title":"Air pollution and cardiovascular disease: a statement for healthcare professionals from the expert panel on population and prevention science of the american heart association","volume":"109","author":"Brook","year":"2004","journal-title":"Circulation"},{"issue":"3","key":"10.1016\/j.envint.2018.06.041_bb0035","doi-asserted-by":"crossref","first-page":"245","DOI":"10.3109\/08958370903207274","article-title":"Impact of ambient air pollution on the differential white blood cell count in patients with chronic pulmonary disease","volume":"22","author":"Bruske","year":"2010","journal-title":"Inhal. Toxicol."},{"issue":"1","key":"10.1016\/j.envint.2018.06.041_bb0040","doi-asserted-by":"crossref","DOI":"10.1183\/13993003.02127-2015","article-title":"Ambient air pollution, traffic noise and adult asthma prevalence: a bioshare approach","volume":"49","author":"Cai","year":"2017","journal-title":"Eur. Respir. J."},{"issue":"2","key":"10.1016\/j.envint.2018.06.041_bb0045","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1111\/j.1538-7836.2007.02297.x","article-title":"The decrease of fibrinogen is an early predictor of the severity of postpartum hemorrhage","volume":"5","author":"Charbit","year":"2007","journal-title":"J. Thromb. Haemost."},{"issue":"5","key":"10.1016\/j.envint.2018.06.041_bb0050","doi-asserted-by":"crossref","first-page":"612","DOI":"10.1289\/ehp.10565","article-title":"Metabolic syndrome and inflammatory responses to long-term particulate air pollutants","volume":"116","author":"Chen","year":"2008","journal-title":"Environ. Health Perspect."},{"issue":"4","key":"10.1016\/j.envint.2018.06.041_bb0055","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1164\/rccm.200611-1627OC","article-title":"The effect of urban air pollution on inflammation, oxidative stress, coagulation, and autonomic dysfunction in young adults","volume":"176","author":"Chuang","year":"2007","journal-title":"Am. J. Respir. Crit. Care Med."},{"issue":"3","key":"10.1016\/j.envint.2018.06.041_bb0060","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1183\/09031936.00168813","article-title":"Air pollution and biomarkers of systemic inflammation and tissue repair in copd patients","volume":"44","author":"Dadvand","year":"2014","journal-title":"Eur. Respir. J."},{"issue":"1","key":"10.1016\/j.envint.2018.06.041_bb0065","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1007\/s00281-011-0290-8","article-title":"Fibrinogen as a key regulator of inflammation in disease","volume":"34","author":"Davalos","year":"2012","journal-title":"Semin. Immunopathol."},{"issue":"24","key":"10.1016\/j.envint.2018.06.041_bb0070","doi-asserted-by":"crossref","first-page":"1753","DOI":"10.1056\/NEJM199312093292401","article-title":"An association between air pollution and mortality in six U.S. cities","volume":"329","author":"Dockery","year":"1993","journal-title":"N. Engl. J. Med."},{"issue":"10","key":"10.1016\/j.envint.2018.06.041_bb0075","doi-asserted-by":"crossref","first-page":"1127","DOI":"10.1001\/jama.295.10.1127","article-title":"Fine particulate air pollution and hospital admission for cardiovascular and respiratory diseases","volume":"295","author":"Dominici","year":"2006","journal-title":"JAMA"},{"issue":"7","key":"10.1016\/j.envint.2018.06.041_bb0080","doi-asserted-by":"crossref","first-page":"992","DOI":"10.1289\/ehp.8469","article-title":"Diabetes, obesity, and hypertension may enhance associations between air pollution and markers of systemic inflammation","volume":"114","author":"Dubowsky","year":"2006","journal-title":"Environ. Health Perspect."},{"issue":"7","key":"10.1016\/j.envint.2018.06.041_bb0085","doi-asserted-by":"crossref","first-page":"670","DOI":"10.1136\/thoraxjnl-2012-201871","article-title":"Blood fibrinogen as a biomarker of chronic obstructive pulmonary disease","volume":"68","author":"Duvoix","year":"2013","journal-title":"Thorax"},{"issue":"9","key":"10.1016\/j.envint.2018.06.041_bb0090","doi-asserted-by":"crossref","first-page":"2090","DOI":"10.2337\/dc06-0093","article-title":"Ferritin and transferrin are both predictive of the onset of hyperglycemia in men and women over 3\u202fyears: the data from an epidemiological study on the insulin resistance syndrome (desir) study","volume":"29","author":"Fumeron","year":"2006","journal-title":"Diabetes Care"},{"issue":"3","key":"10.1016\/j.envint.2018.06.041_bb0095","doi-asserted-by":"crossref","first-page":"558","DOI":"10.1183\/09031936.00108814","article-title":"Effects of short- and long-term exposures to ambient air pollution on copd","volume":"44","author":"Garshick","year":"2014","journal-title":"Eur. Respir. J."},{"issue":"6","key":"10.1016\/j.envint.2018.06.041_bb0100","doi-asserted-by":"crossref","first-page":"715","DOI":"10.1165\/rcmb.2007-0179OC","article-title":"Carbon monoxide reversibly alters iron homeostasis and respiratory epithelial cell function","volume":"38","author":"Ghio","year":"2008","journal-title":"Am. J. Respir. Cell Mol. Biol."},{"issue":"14","key":"10.1016\/j.envint.2018.06.041_bb0105","doi-asserted-by":"crossref","first-page":"1932","DOI":"10.1001\/jama.1985.03360140090031","article-title":"Prognostic importance of the white blood cell count for coronary, cancer, and all-cause mortality","volume":"254","author":"Grimm","year":"1985","journal-title":"JAMA"},{"issue":"3","key":"10.1016\/j.envint.2018.06.041_bb0110","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1097\/EDE.0000000000000267","article-title":"Long-term exposure to air pollution and markers of inflammation, coagulation, and endothelial activation: a repeat-measures analysis in the multi-ethnic study of atherosclerosis (mesa)","volume":"26","author":"Hajat","year":"2015","journal-title":"Epidemiology"},{"key":"10.1016\/j.envint.2018.06.041_bb0115","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1016\/j.taap.2017.12.006","article-title":"Adrenergic and glucocorticoid receptor antagonists reduce ozone-induced lung injury and inflammation","volume":"339","author":"Henriquez","year":"2018","journal-title":"Toxicol. Appl. Pharmacol."},{"issue":"8","key":"10.1016\/j.envint.2018.06.041_bb0120","doi-asserted-by":"crossref","first-page":"1302","DOI":"10.1289\/ehp.0800362","article-title":"Chronic residential exposure to particulate matter air pollution and systemic inflammatory markers","volume":"117","author":"Hoffmann","year":"2009","journal-title":"Environ. Health Perspect."},{"issue":"14","key":"10.1016\/j.envint.2018.06.041_bb0125","doi-asserted-by":"crossref","first-page":"1310","DOI":"10.1056\/NEJMoa1107477","article-title":"C-reactive protein, fibrinogen, and cardiovascular disease prediction","volume":"367","author":"Kaptoge","year":"2012","journal-title":"N. Engl. J. Med."},{"issue":"3","key":"10.1016\/j.envint.2018.06.041_bb0130","doi-asserted-by":"crossref","first-page":"304","DOI":"10.4046\/trd.2017.80.3.304","article-title":"Systemic white blood cell count as a biomarker associated with severity of chronic obstructive lung disease","volume":"80","author":"Koo","year":"2017","journal-title":"Tuberc. Respir. Dis. (Seoul)"},{"issue":"16","key":"10.1016\/j.envint.2018.06.041_bb0135","doi-asserted-by":"crossref","first-page":"1667","DOI":"10.1056\/NEJMp068070","article-title":"The challenge of subgroup analyses-reporting without distorting","volume":"354","author":"Lagakos","year":"2006","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.envint.2018.06.041_bb0140","article-title":"Short-term air pollution exposure aggravates Parkinson's disease in a population-based cohort","volume":"7","author":"Lee","year":"2017","journal-title":"Sci. Rep."},{"issue":"2\u20133","key":"10.1016\/j.envint.2018.06.041_bb0145","first-page":"133","article-title":"Effect of particulate matter air pollution on c-reactive protein: a review of epidemiologic studies","volume":"27","author":"Li","year":"2012","journal-title":"Rev. Environ. Health"},{"issue":"9","key":"10.1016\/j.envint.2018.06.041_bb0150","doi-asserted-by":"crossref","first-page":"1793","DOI":"10.1161\/ATVBAHA.117.309799","article-title":"Short-term exposure to ambient air pollution and biomarkers of systemic inflammation: the Framingham heart study","volume":"37","author":"Li","year":"2017","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"issue":"2","key":"10.1016\/j.envint.2018.06.041_bb0155","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1016\/j.neuro.2004.09.001","article-title":"Alteration of serum concentrations of manganese, iron, ferritin, and transferrin receptor following exposure to welding fumes among career welders","volume":"26","author":"Lu","year":"2005","journal-title":"Neurotoxicology"},{"issue":"3","key":"10.1016\/j.envint.2018.06.041_bb0160","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1002\/jcla.10072","article-title":"D-dimer and its relationship to fibrinogen\/fibrin degradation products (fdps) in disorders associated with activation of coagulation or fibrinolytic systems","volume":"17","author":"Moresco","year":"2003","journal-title":"J. Clin. Lab. Anal."},{"issue":"3","key":"10.1016\/j.envint.2018.06.041_bb0165","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1016\/j.thromres.2013.12.004","article-title":"Carbon monoxide: Anticoagulant or procoagulant?","volume":"133","author":"Nielsen","year":"2014","journal-title":"Thromb. Res."},{"issue":"11","key":"10.1016\/j.envint.2018.06.041_bb0170","doi-asserted-by":"crossref","first-page":"747","DOI":"10.1136\/oem.2008.043471","article-title":"Associations of long- and short-term air pollution exposure with markers of inflammation and coagulation in a population sample","volume":"66","author":"Panasevich","year":"2009","journal-title":"Occup. Environ. Med."},{"issue":"1","key":"10.1016\/j.envint.2018.06.041_bb0175","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1186\/s12967-016-1006-6","article-title":"Fibrinogen consumption is related to intracranial clot burden in acute ischemic stroke: a retrospective hyperdense artery study","volume":"14","author":"Pikija","year":"2016","journal-title":"J. Transl. Med."},{"issue":"9","key":"10.1016\/j.envint.2018.06.041_bb0180","doi-asserted-by":"crossref","first-page":"1132","DOI":"10.1001\/jama.287.9.1132","article-title":"Lung cancer, cardiopulmonary mortality, and long-term exposure to fine particulate air pollution","volume":"287","author":"Pope","year":"2002","journal-title":"JAMA"},{"issue":"1","key":"10.1016\/j.envint.2018.06.041_bb0185","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1186\/1743-8977-1-2","article-title":"Cardiovascular effects in patrol officers are associated with fine particulate matter from brake wear and engine emissions","volume":"1","author":"Riediker","year":"2004","journal-title":"Part. Fibre Toxicol."},{"issue":"4","key":"10.1016\/j.envint.2018.06.041_bb0190","doi-asserted-by":"crossref","first-page":"432","DOI":"10.1164\/rccm.200507-1123OC","article-title":"Air pollution and markers of inflammation and coagulation in patients with coronary heart disease","volume":"173","author":"Ruckerl","year":"2006","journal-title":"Am. J. Respir. Crit. Care Med."},{"issue":"7","key":"10.1016\/j.envint.2018.06.041_bb0195","doi-asserted-by":"crossref","first-page":"1072","DOI":"10.1289\/ehp.10021","article-title":"Air pollution and inflammation (interleukin-6, c-reactive protein, fibrinogen) in myocardial infarction survivors","volume":"115","author":"Ruckerl","year":"2007","journal-title":"Environ. Health Perspect."},{"issue":"3","key":"10.1016\/j.envint.2018.06.041_bb0200","doi-asserted-by":"crossref","first-page":"803","DOI":"10.1161\/01.CIR.86.3.803","article-title":"High stored iron levels are associated with excess risk of myocardial infarction in eastern Finnish men","volume":"86","author":"Salonen","year":"1992","journal-title":"Circulation"},{"issue":"11","key":"10.1016\/j.envint.2018.06.041_bb0205","doi-asserted-by":"crossref","first-page":"1027","DOI":"10.1136\/thx.54.11.1027","article-title":"Particulate air pollution and the blood","volume":"54","author":"Seaton","year":"1999","journal-title":"Thorax"},{"issue":"14","key":"10.1016\/j.envint.2018.06.041_bb0210","doi-asserted-by":"crossref","first-page":"1634","DOI":"10.1161\/01.CIR.102.14.1634","article-title":"Association of fibrinogen with cardiovascular risk factors and cardiovascular disease in the Framingham offspring population","volume":"102","author":"Stec","year":"2000","journal-title":"Circulation"},{"issue":"4","key":"10.1016\/j.envint.2018.06.041_bb0215","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0152458","article-title":"Inflammatory cytokines and white blood cell counts response to environmental levels of diesel exhaust and ozone inhalation exposures","volume":"11","author":"Stiegel","year":"2016","journal-title":"PLoS One"},{"issue":"Suppl. 1","key":"10.1016\/j.envint.2018.06.041_bb0220","doi-asserted-by":"crossref","first-page":"S74","DOI":"10.1097\/EDE.0000000000000715","article-title":"Association between long-term exposure to traffic-related air pollution and inflammatory and thrombotic markers in middle-aged adults","volume":"28","author":"Su","year":"2017","journal-title":"Epidemiology"},{"issue":"9","key":"10.1016\/j.envint.2018.06.041_bb0225","doi-asserted-by":"crossref","first-page":"2070","DOI":"10.1182\/blood-2008-07-167411","article-title":"Systemic blood coagulation activation in acute coronary syndromes","volume":"113","author":"Undas","year":"2009","journal-title":"Blood"},{"issue":"9","key":"10.1016\/j.envint.2018.06.041_bb0230","doi-asserted-by":"crossref","first-page":"656","DOI":"10.1136\/oemed-2014-102800","article-title":"Long-term residential exposure to urban air pollution, and repeated measures of systemic blood markers of inflammation and coagulation","volume":"72","author":"Viehmann","year":"2015","journal-title":"Occup. Environ. Med."},{"issue":"Pt 3","key":"10.1016\/j.envint.2018.06.041_bb0235","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1042\/bj20021302","article-title":"Effects of nitrogen monoxide and carbon monoxide on molecular and cellular iron metabolism: mirror-image effector molecules that target iron","volume":"369","author":"Watts","year":"2003","journal-title":"Biochem. J."},{"issue":"6","key":"10.1016\/j.envint.2018.06.041_bb0240","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1016\/j.breast.2015.09.007","article-title":"The preoperative plasma fibrinogen level is an independent prognostic factor for overall survival of breast cancer patients who underwent surgical treatment","volume":"24","author":"Wen","year":"2015","journal-title":"Breast"},{"key":"10.1016\/j.envint.2018.06.041_bb0245","series-title":"Air Quality Guidelines: Global Update 2005. Particulate Matter, Ozone, Nitrogen Dioxide and Sulfur Dioxide","author":"World Health Organization","year":"2006"},{"issue":"5","key":"10.1016\/j.envint.2018.06.041_bb0250","doi-asserted-by":"crossref","first-page":"1347","DOI":"10.1093\/ije\/dyl132","article-title":"Inflammatory markers and particulate air pollution: characterizing the pathway to disease","volume":"35","author":"Zeka","year":"2006","journal-title":"Int. J. Epidemiol."}],"container-title":["Environment International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0160412018305166?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0160412018305166?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,27]],"date-time":"2025-09-27T11:30:50Z","timestamp":1758972650000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0160412018305166"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,10]]},"references-count":50,"alternative-id":["S0160412018305166"],"URL":"https:\/\/doi.org\/10.1016\/j.envint.2018.06.041","relation":{},"ISSN":["0160-4120"],"issn-type":[{"value":"0160-4120","type":"print"}],"subject":[],"published":{"date-parts":[[2018,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Short- and long-term exposure to ambient air pollution and circulating biomarkers of inflammation in non-smokers: A hospital-based cohort study in South Korea","name":"articletitle","label":"Article Title"},{"value":"Environment International","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.envint.2018.06.041","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}