{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T22:05:50Z","timestamp":1790028350488,"version":"4.0.1"},"reference-count":58,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2018,12,1]],"date-time":"2018-12-01T00:00:00Z","timestamp":1543622400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,12,1]],"date-time":"2018-12-01T00:00:00Z","timestamp":1543622400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2019,1,29]],"date-time":"2019-01-29T00:00:00Z","timestamp":1548720000000},"content-version":"vor","delay-in-days":59,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000024","name":"Canadian Institutes of Health Research","doi-asserted-by":"publisher","award":["246200"],"award-info":[{"award-number":["246200"]}],"id":[{"id":"10.13039\/501100000024","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000155","name":"Social Sciences and Humanities Research Council","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000155","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Canada Institute for Innovation"},{"name":"Statistics Canada"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Environment International"],"published-print":{"date-parts":[[2018,12]]},"DOI":"10.1016\/j.envint.2018.08.040","type":"journal-article","created":{"date-parts":[[2018,8,29]],"date-time":"2018-08-29T21:08:00Z","timestamp":1535576880000},"page":"23-30","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":52,"special_numbering":"P1","title":["A population-based birth cohort study of the association between childhood-onset asthma and exposure to industrial air pollutant emissions"],"prefix":"10.1016","volume":"121","author":[{"given":"St\u00e9phane","family":"Buteau","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mari\u00e8ve","family":"Doucet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Louis-Fran\u00e7ois","family":"T\u00e9treault","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philippe","family":"Gamache","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michel","family":"Fournier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Allan","family":"Brand","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tom","family":"Kosatsky","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Audrey","family":"Smargiassi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.envint.2018.08.040_bb9010","doi-asserted-by":"crossref","first-page":"716","DOI":"10.1109\/TAC.1974.1100705","article-title":"A new look at the statistical model identification","volume":"19","author":"Akaike","year":"1974","journal-title":"IEEE Trans. Autom. Control"},{"key":"10.1016\/j.envint.2018.08.040_bb0005","doi-asserted-by":"crossref","first-page":"710","DOI":"10.1136\/thx.2007.085480","article-title":"Ambient air pollution triggers wheezing symptoms in infants","volume":"63","author":"Andersen","year":"2008","journal-title":"Thorax"},{"key":"10.1016\/j.envint.2018.08.040_bb0010","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1136\/thorax.56.3.228","article-title":"Proximity to coke works and hospital admissions for respiratory and cardiovascular disease in England and Wales","volume":"56","author":"Aylin","year":"2001","journal-title":"Thorax"},{"key":"10.1016\/j.envint.2018.08.040_bb0015","doi-asserted-by":"crossref","first-page":"226","DOI":"10.24095\/hpcdp.34.4.06","article-title":"Quebec integrated chronic disease surveillance system (QICDSS), an innovative approach","volume":"34","author":"Blais","year":"2014","journal-title":"Chronic Dis Inj Can."},{"key":"10.1016\/j.envint.2018.08.040_bb0020","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1186\/1476-069X-8-17","article-title":"Does traffic exhaust contribute to the development of asthma and allergic sensitization in children: findings from recent cohort studies","volume":"8","author":"Braback","year":"2009","journal-title":"Environ. Health"},{"key":"10.1016\/j.envint.2018.08.040_bb0025","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/j.envint.2016.05.002","article-title":"Respiratory hospital admissions in young children living near metal smelters, pulp mills and oil refineries in two Canadian provinces","volume":"94","author":"Brand","year":"2016","journal-title":"Environ. Int."},{"key":"10.1016\/j.envint.2018.08.040_bb0030","doi-asserted-by":"crossref","first-page":"1092","DOI":"10.1164\/rccm.200108-007OC","article-title":"Air pollution from traffic and the development of respiratory infections and asthmatic and allergic symptoms in children","volume":"166","author":"Brauer","year":"2002","journal-title":"Am. J. Respir. Crit. Care Med."},{"key":"10.1016\/j.envint.2018.08.040_bb0035","doi-asserted-by":"crossref","first-page":"879","DOI":"10.1183\/09031936.00083406","article-title":"Air pollution and development of asthma, allergy and infections in a birth cohort","volume":"29","author":"Brauer","year":"2007","journal-title":"Eur. Respir. J."},{"key":"10.1016\/j.envint.2018.08.040_bb0040","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1097\/EDE.0b013e318276c005","article-title":"Long-term exposure to traffic-related air pollution and cardiovascular mortality","volume":"24","author":"Chen","year":"2013","journal-title":"Epidemiology"},{"key":"10.1016\/j.envint.2018.08.040_bb0045","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1289\/ehp.0900916","article-title":"Effect of early life exposure to air pollution on development of childhood asthma","volume":"118","author":"Clark","year":"2010","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.envint.2018.08.040_bb0050","doi-asserted-by":"crossref","first-page":"1180","DOI":"10.1289\/ehp.1409276","article-title":"Ambient PM2.5, O3, and NO2 exposures and associations with mortality over 16 years of follow-up in the Canadian census health and environment cohort (CanCHEC)","volume":"123","author":"Crouse","year":"2015","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.envint.2018.08.040_bb0055","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/j.envint.2013.01.014","article-title":"Acute changes in lung function associated with proximity to a steel plant: a randomized study","volume":"55","author":"Dales","year":"2013","journal-title":"Environ. Int."},{"key":"10.1016\/j.envint.2018.08.040_bb0060","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1016\/j.scitotenv.2009.10.024","article-title":"Proximity to chipboard industries increases the risk of respiratory and irritation symptoms in children: the Viadana study","volume":"408","author":"de Marco","year":"2010","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.envint.2018.08.040_bb0065","author":"Environment and Climate Change Canada"},{"key":"10.1016\/j.envint.2018.08.040_bb0070","author":"Environment Canada"},{"key":"10.1016\/j.envint.2018.08.040_bb9000","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1146\/annurev.publhealth.20.1.145","article-title":"Time-dependent covariates in the Cox proportional-hazards regression model","volume":"20","author":"Fisher","year":"1999","journal-title":"Annu. Rev. Public Health"},{"key":"10.1016\/j.envint.2018.08.040_bb0075","doi-asserted-by":"crossref","first-page":"596","DOI":"10.1164\/rccm.200906-0858OC","article-title":"Traffic-related air pollution and the development of asthma and allergies during the first 8 years of life","volume":"181","author":"Gehring","year":"2010","journal-title":"Am. J. Respir. Crit. Care Med."},{"key":"10.1016\/j.envint.2018.08.040_bb0080","doi-asserted-by":"crossref","first-page":"1859","DOI":"10.1001\/jama.290.14.1859","article-title":"Association of low-level ozone and fine particles with respiratory symptoms in children with asthma","volume":"290","author":"Gent","year":"2003","journal-title":"JAMA"},{"key":"10.1016\/j.envint.2018.08.040_bb0085","doi-asserted-by":"crossref","first-page":"728","DOI":"10.1093\/aje\/kwq189","article-title":"Trends in asthma prevalence and incidence in Ontario, Canada, 1996\u20132005: a population study","volume":"172","author":"Gershon","year":"2010","journal-title":"Am. J. Epidemiol."},{"key":"10.1016\/j.envint.2018.08.040_bb0090","doi-asserted-by":"crossref","first-page":"1581","DOI":"10.1016\/S0140-6736(14)60617-6","article-title":"Outdoor air pollution and asthma","volume":"383","author":"Guarnieri","year":"2014","journal-title":"Lancet"},{"key":"10.1016\/j.envint.2018.08.040_bb0095","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1016\/j.iac.2008.03.008","article-title":"Traffic, outdoor air pollution, and asthma","volume":"28","author":"Holguin","year":"2008","journal-title":"Immunol. Allergy Clin. N. Am."},{"key":"10.1016\/j.envint.2018.08.040_bb0100","doi-asserted-by":"crossref","first-page":"1433","DOI":"10.1289\/ehp.10968","article-title":"Traffic-related air pollution and asthma onset in children: a prospective cohort study with individual exposure measurement","volume":"116","author":"Jerrett","year":"2008","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.envint.2018.08.040_bb0105","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.envint.2016.11.012","article-title":"Exposure to traffic-related air pollution and risk of development of childhood asthma: a systematic review and meta-analysis","volume":"100","author":"Khreis","year":"2017","journal-title":"Environ. Int."},{"key":"10.1016\/j.envint.2018.08.040_bb0110","doi-asserted-by":"crossref","first-page":"717","DOI":"10.1016\/S0091-6749(99)70280-0","article-title":"Air pollution and asthma","volume":"104","author":"Koenig","year":"1999","journal-title":"J. Allergy Clin. Immunol."},{"key":"10.1016\/j.envint.2018.08.040_bb0115","doi-asserted-by":"crossref","first-page":"77","DOI":"10.5539\/ep.v4n2p77","article-title":"Hospitalizations for respiratory problems and exposure to industrial emissions in children","volume":"4","author":"Labelle","year":"2015","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.envint.2018.08.040_bb0120","doi-asserted-by":"crossref","first-page":"813","DOI":"10.1093\/aje\/kwf122","article-title":"Modeling smoking history: a comparison of different approaches","volume":"156","author":"Leffondre","year":"2002","journal-title":"Am. J. Epidemiol."},{"key":"10.1016\/j.envint.2018.08.040_bb0125","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1038\/jes.2013.27","article-title":"Short-term risk of hospitalization for asthma or bronchiolitis in children living near an aluminum smelter","volume":"23","author":"Lewin","year":"2013","journal-title":"J. Expo. Sci. Environ. Epidemiol."},{"key":"10.1016\/j.envint.2018.08.040_bb0130","doi-asserted-by":"crossref","first-page":"927","DOI":"10.1093\/aje\/kwk088","article-title":"Air pollution sources and childhood asthma attacks in Catano, Puerto Rico","volume":"165","author":"Loyo-Berrios","year":"2007","journal-title":"Am. J. Epidemiol."},{"key":"10.1016\/j.envint.2018.08.040_bb0135","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/j.ijheh.2013.03.015","article-title":"Children living near chipboard and wood industries are at an increased risk of hospitalization for respiratory diseases: a prospective study","volume":"217","author":"Marchetti","year":"2014","journal-title":"Int. J. Hyg. Environ. Health"},{"key":"10.1016\/j.envint.2018.08.040_bb0140","doi-asserted-by":"crossref","first-page":"1021","DOI":"10.1289\/ehp.0901232","article-title":"Childhood incident asthma and traffic-related air pollution at home and school","volume":"118","author":"McConnell","year":"2010","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.envint.2018.08.040_bb0145","doi-asserted-by":"crossref","first-page":"1331","DOI":"10.1164\/rccm.200701-036OC","article-title":"Atopic diseases, allergic sensitization, and exposure to traffic-related air pollution in children","volume":"177","author":"Morgenstern","year":"2008","journal-title":"Am. J. Respir. Crit. Care Med."},{"key":"10.1016\/j.envint.2018.08.040_bb0150","doi-asserted-by":"crossref","first-page":"1133","DOI":"10.1016\/j.jaci.2008.02.020","article-title":"Acute respiratory health effects of air pollution on children with asthma in US inner cities","volume":"121","author":"O'Connor","year":"2008","journal-title":"J. Allergy Clin. Immunol."},{"key":"10.1016\/j.envint.2018.08.040_bb0155","doi-asserted-by":"crossref","first-page":"839","DOI":"10.1289\/ehp.11491","article-title":"Long-term traffic-related exposures and asthma onset in schoolchildren in Oslo, Norway","volume":"117","author":"Oftedal","year":"2009","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.envint.2018.08.040_bb0160","doi-asserted-by":"crossref","first-page":"178","DOI":"10.24095\/hpcdp.29.4.05","article-title":"A deprivation index for health planning in Canada","volume":"29","author":"Pampalon","year":"2009","journal-title":"Chronic Dis. Can."},{"key":"10.1016\/j.envint.2018.08.040_bb0165","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/ppul.21321","article-title":"Global strategy for the diagnosis and management of asthma in children 5\u202fyears and younger","volume":"46","author":"Pedersen","year":"2011","journal-title":"Pediatr. Pulmonol."},{"key":"10.1016\/j.envint.2018.08.040_bb0170","author":"PHAC (Public Health Agency of Canada)"},{"key":"10.1016\/j.envint.2018.08.040_bb0175","doi-asserted-by":"crossref","first-page":"623","DOI":"10.2105\/AJPH.79.5.623","article-title":"Respiratory disease associated with community air pollution and a steel mill, Utah Valley","volume":"79","author":"Pope","year":"1989","journal-title":"Am. J. Public Health"},{"key":"10.1016\/j.envint.2018.08.040_bb0180","doi-asserted-by":"crossref","first-page":"1123","DOI":"10.1164\/ajrccm\/145.5.1123","article-title":"Acute health effects of PM10 pollution on symptomatic and asymptomatic children","volume":"145","author":"Pope","year":"1992","journal-title":"Am. Rev. Respir. Dis."},{"key":"10.1016\/j.envint.2018.08.040_bb0185","doi-asserted-by":"crossref","first-page":"1057","DOI":"10.1016\/j.jaci.2014.05.012","article-title":"Trends in the age of diagnosis of childhood asthma","volume":"134","author":"Radhakrishnan","year":"2014","journal-title":"J. Allergy Clin. Immunol."},{"key":"10.1016\/j.envint.2018.08.040_bb0190","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1016\/j.scitotenv.2011.09.078","article-title":"Proximity to wood factories and hospitalizations for respiratory diseases in children","volume":"410\u2013411","author":"Rava","year":"2011","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.envint.2018.08.040_bb0195","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/j.envint.2011.07.011","article-title":"Proximity to wood industries and respiratory symptoms in children: a sensitivity analysis","volume":"38","author":"Rava","year":"2012","journal-title":"Environ. Int."},{"key":"10.1016\/j.envint.2018.08.040_bb0200","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1016\/j.envres.2014.05.022","article-title":"Asthma, respiratory symptoms and lung function in children living near a petrochemical site","volume":"133","author":"Rovira","year":"2014","journal-title":"Environ. Res."},{"key":"10.1016\/j.envint.2018.08.040_bb0205","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1080\/00039890209602084","article-title":"Effects of air pollution on the prevalence and incidence of asthma in children","volume":"57","author":"Shima","year":"2002","journal-title":"Arch. Environ. Health"},{"key":"10.1016\/j.envint.2018.08.040_bb0210","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1289\/ehp.0800010","article-title":"Risk of asthmatic episodes in children exposed to sulfur dioxide stack emissions from a refinery point source in Montreal, Canada","volume":"117","author":"Smargiassi","year":"2009","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.envint.2018.08.040_bb0215","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1016\/j.envres.2014.03.030","article-title":"Associations between personal exposure to air pollutants and lung function tests and cardiovascular indices among children with asthma living near an industrial complex and petroleum refineries","volume":"132","author":"Smargiassi","year":"2014","journal-title":"Environ. Res."},{"key":"10.1016\/j.envint.2018.08.040_bb0220","author":"Statistics Canada"},{"key":"10.1016\/j.envint.2018.08.040_bb0225","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1093\/aje\/kwh211","article-title":"Monte Carlo sensitivity analysis and Bayesian analysis of smoking as an unmeasured confounder in a study of silica and lung cancer","volume":"160","author":"Steenland","year":"2004","journal-title":"Am. J. Epidemiol."},{"key":"10.1016\/j.envint.2018.08.040_bb0230","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1586\/1744666X.5.1.77","article-title":"Epidemiology of asthma: risk factors for development","volume":"5","author":"Subbarao","year":"2009","journal-title":"Expert. Rev. Clin. Immunol."},{"key":"10.1016\/j.envint.2018.08.040_bb0235","doi-asserted-by":"crossref","first-page":"E181","DOI":"10.1503\/cmaj.080612","article-title":"Asthma: epidemiology, etiology and risk factors","volume":"181","author":"Subbarao","year":"2009","journal-title":"CMAJ"},{"key":"10.1016\/j.envint.2018.08.040_bb0240","doi-asserted-by":"crossref","first-page":"1276","DOI":"10.1289\/ehp.1509838","article-title":"Childhood exposure to ambient air pollutants and the onset of asthma: an administrative cohort study in Qu\u00e9bec","volume":"124","author":"T\u00e9treault","year":"2016","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.envint.2018.08.040_bb0245","doi-asserted-by":"crossref","first-page":"1475","DOI":"10.1093\/ntr\/ntt033","article-title":"Meta-analysis of the association between secondhand smoke exposure and physician-diagnosed childhood asthma","volume":"15","author":"Tinuoye","year":"2013","journal-title":"Nicotine Tob. Res."},{"key":"10.1016\/j.envint.2018.08.040_bb9005","series-title":"Modeling Survival Data: Extending the Cox Model","author":"Therneau","year":"2000"},{"key":"10.1016\/j.envint.2018.08.040_bb0250","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1016\/j.jaci.2005.01.056","article-title":"The role of air pollution in asthma and other pediatric morbidities","volume":"115","author":"Trasande","year":"2005","journal-title":"J. Allergy Clin. Immunol."},{"key":"10.1016\/j.envint.2018.08.040_bb0255","doi-asserted-by":"crossref","first-page":"920","DOI":"10.1136\/oem.2010.062521","article-title":"Associations between cigarette smoking, obesity, sociodemographic characteristics and remote-sensing-derived estimates of ambient PM2.5: results from a Canadian population-based survey","volume":"68","author":"Villeneuve","year":"2011","journal-title":"Occup. Environ. Med."},{"key":"10.1016\/j.envint.2018.08.040_bb0260","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1016\/j.envpol.2012.12.022","article-title":"A cohort study of intra-urban variations in volatile organic compounds and mortality, Toronto, Canada","volume":"183","author":"Villeneuve","year":"2013","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.envint.2018.08.040_bb0265","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/S0091-6749(00)90171-4","article-title":"The environmental predictors of allergic disease","volume":"105","author":"von Mutius","year":"2000","journal-title":"J. Allergy Clin. Immunol."},{"key":"10.1016\/j.envint.2018.08.040_bb0270","author":"WHO (World Health Organization)"},{"key":"10.1016\/j.envint.2018.08.040_bb0275","doi-asserted-by":"crossref","first-page":"632","DOI":"10.1016\/j.jaci.2008.09.052","article-title":"Increased asthma and respiratory symptoms in children exposed to petrochemical pollution","volume":"123","author":"Wichmann","year":"2009","journal-title":"J. Allergy Clin. Immunol."}],"updated-by":[{"DOI":"10.1016\/j.envint.2018.11.023","type":"erratum","label":"Erratum","source":"publisher","updated":{"date-parts":[[2018,12,1]],"date-time":"2018-12-01T00:00:00Z","timestamp":1543622400000}}],"container-title":["Environment International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S016041201830535X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S016041201830535X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,27]],"date-time":"2025-09-27T11:31:21Z","timestamp":1758972681000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S016041201830535X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,12]]},"references-count":58,"alternative-id":["S016041201830535X"],"URL":"https:\/\/doi.org\/10.1016\/j.envint.2018.08.040","relation":{},"ISSN":["0160-4120"],"issn-type":[{"value":"0160-4120","type":"print"}],"subject":[],"published":{"date-parts":[[2018,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A population-based birth cohort study of the association between childhood-onset asthma and exposure to industrial air pollutant emissions","name":"articletitle","label":"Article Title"},{"value":"Environment International","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.envint.2018.08.040","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}]}}