{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T19:21:17Z","timestamp":1790882477693,"version":"4.1.0"},"reference-count":82,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,7,1]],"date-time":"2021-07-01T00:00:00Z","timestamp":1625097600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,7,1]],"date-time":"2021-07-01T00:00:00Z","timestamp":1625097600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,2,15]],"date-time":"2021-02-15T00:00:00Z","timestamp":1613347200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Environment International"],"published-print":{"date-parts":[[2021,7]]},"DOI":"10.1016\/j.envint.2021.106466","type":"journal-article","created":{"date-parts":[[2021,3,8]],"date-time":"2021-03-08T23:41:49Z","timestamp":1615246909000},"page":"106466","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":43,"special_numbering":"C","title":["A Point Prevalence Survey of Antibiotic Resistance in the Irish Environment, 2018\u20132019"],"prefix":"10.1016","volume":"152","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4882-6891","authenticated-orcid":false,"given":"Brigid","family":"Hooban","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5337-0505","authenticated-orcid":false,"given":"Kelly","family":"Fitzhenry","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Niamh","family":"Cahill","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aoife","family":"Joyce","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Louise","family":"O' Connor","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3554-4254","authenticated-orcid":false,"given":"James E.","family":"Bray","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sylvain","family":"Brisse","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Virginie","family":"Passet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raza","family":"Abbas Syed","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"Cormican","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dearbh\u00e1ile","family":"Morris","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.envint.2021.106466_b0005","doi-asserted-by":"crossref","first-page":"2016","DOI":"10.1080\/10643389.2019.1692611","article-title":"Understanding human health risks caused by antibiotic resistant bacteria (ARB) and antibiotic resistance genes (ARG) in water environments: Current knowledge and questions to be answered","volume":"50","author":"Amarasiri","year":"2020","journal-title":"Critical Reviews in Environmental Science and Technology"},{"key":"10.1016\/j.envint.2021.106466_b0010","doi-asserted-by":"crossref","first-page":"1564","DOI":"10.3201\/eid2309.170560","article-title":"Emergence of Plasmid-Mediated Fosfomycin-Resistance Genes among Escherichia coli Isolates","volume":"23","author":"Benzerara","year":"2017","journal-title":"France. Emerging infectious diseases"},{"key":"10.1016\/j.envint.2021.106466_b0015","doi-asserted-by":"crossref","first-page":"1812","DOI":"10.3201\/eid2011.140206","article-title":"Genomic definition of hypervirulent and multidrug-resistant Klebsiella pneumoniae clonal groups","volume":"20","author":"Bialek-Davenet","year":"2014","journal-title":"Emerging infectious diseases"},{"key":"10.1016\/j.envint.2021.106466_b0020","author":"Birkett","year":"2007","journal-title":"Real-time TaqMan PCR for rapid detection and typing of genes encoding CTX-M extended-spectrum \u03b2-lactamases."},{"key":"10.1016\/j.envint.2021.106466_b0025","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2020.115081","article-title":"Environmental dissemination of carbapenemase-producing Enterobacteriaceae in rivers in Switzerland","volume":"265","author":"Bleichenbacher","year":"2020","journal-title":"Environmental Pollution"},{"key":"10.1016\/j.envint.2021.106466_b0030","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0169445","article-title":"Genetic Attributes of E. coli Isolates from Chlorinated Drinking Water","volume":"12","author":"Blyton","year":"2017","journal-title":"PloS one"},{"key":"10.1016\/j.envint.2021.106466_b0035","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1093\/jac\/dkp453","article-title":"Emergence of clonally related Klebsiella pneumoniae isolates of sequence type 258 producing KPC-2 carbapenemase in Belgium","volume":"65","author":"Bogaerts","year":"2009","journal-title":"Journal of Antimicrobial Chemotherapy"},{"key":"10.1016\/j.envint.2021.106466_b0040","doi-asserted-by":"crossref","first-page":"1856","DOI":"10.1093\/jac\/dkz136","article-title":"An MLST approach to support tracking of plasmids carrying OXA-48-like carbapenemase","volume":"74","author":"Brehony","year":"2019","journal-title":"Journal of Antimicrobial Chemotherapy"},{"key":"10.1016\/j.envint.2021.106466_b0045","doi-asserted-by":"crossref","first-page":"618","DOI":"10.1016\/j.scitotenv.2019.03.428","article-title":"Hospital effluent: A reservoir for carbapenemase-producing Enterobacterales?","volume":"672","author":"Cahill","year":"2019","journal-title":"Science of The Total Environment"},{"key":"10.1016\/j.envint.2021.106466_b0050","doi-asserted-by":"crossref","DOI":"10.3389\/fmicb.2017.02232","article-title":"Occurrence of Extended Spectrum \u03b2-Lactamases, KPC-Type, and MCR-1.2-Producing Enterobacteriaceae From Wells, River Water, and Wastewater Treatment Plants in Oltrep\u00f2 Pavese Area, Northern Italy","volume":"8","author":"Caltagirone","year":"2017","journal-title":"Frontiers in microbiology"},{"key":"10.1016\/j.envint.2021.106466_b0055","doi-asserted-by":"crossref","first-page":"110","DOI":"10.3389\/fmicb.2012.00110","article-title":"CTX-M Enzymes: Origin and Diffusion","volume":"3","author":"Cant\u00f3n","year":"2012","journal-title":"Frontiers in Microbiology"},{"key":"10.1016\/j.envint.2021.106466_b0060","unstructured":"Central Statistics Office. 2016. https:\/\/statbank.cso.ie\/px\/pxeirestat\/Statire\/SelectVarVal\/Define.asp?maintable=E2001&PLanguage=0 (Accessed 27\/07\/2020)."},{"key":"10.1016\/j.envint.2021.106466_b0065","doi-asserted-by":"crossref","first-page":"1542","DOI":"10.1128\/AAC.02332-12","article-title":"Complete Sequence of a blaKPC-2-Harboring IncFIIK1 Plasmid from a Klebsiella pneumoniae Sequence Type 258 Strain","volume":"57","author":"Chen","year":"2013","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.envint.2021.106466_b0070","doi-asserted-by":"crossref","first-page":"2505","DOI":"10.2147\/IDR.S208122","article-title":"Prevalence and molecular epidemiology characteristics of carbapenem-resistant Escherichia coli in Heilongjiang Province","volume":"12","author":"Cheng","year":"2019","journal-title":"China. Infection and drug resistance"},{"key":"10.1016\/j.envint.2021.106466_b0075","doi-asserted-by":"crossref","first-page":"16","DOI":"10.3390\/antibiotics8010016","article-title":"Mapping and Analysing Potential Sources and Transmission Routes of Antimicrobial Resistant Organisms in the Environment using Geographic Information Systems\u2014An Exploratory Study","volume":"8","author":"Chique","year":"2019","journal-title":"Antibiotics"},{"key":"10.1016\/j.envint.2021.106466_b0080","doi-asserted-by":"crossref","DOI":"10.1016\/j.watres.2020.116496","article-title":"Contamination of domestic groundwater systems by verotoxigenic escherichia coli (VTEC), 2003\u20132019: A global scoping review","volume":"188","author":"Chique","year":"2021","journal-title":"Water Research"},{"key":"10.1016\/j.envint.2021.106466_b0085","doi-asserted-by":"crossref","DOI":"10.1016\/j.watres.2020.115726","article-title":"Cryptosporidium spp. in groundwater supplies intended for human consumption \u2013 A descriptive review of global prevalence, risk factors and knowledge gaps","volume":"176","author":"Chique","year":"2020","journal-title":"Water Research"},{"key":"10.1016\/j.envint.2021.106466_b0090","series-title":"CLSI M100-ED30:2020 Performance Standards for Antimicrobial Susceptibility Testing","author":"CLSI","year":"2020"},{"key":"10.1016\/j.envint.2021.106466_b0095","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1017\/S0950268811001038","article-title":"The role of drinking water in the transmission of antimicrobial-resistant E. coli","volume":"140","author":"Coleman","year":"2012","journal-title":"Epidemiol Infect"},{"key":"10.1016\/j.envint.2021.106466_b0100","doi-asserted-by":"crossref","first-page":"e00438","DOI":"10.1128\/genomeA.00438-16","article-title":"Complete Genome Sequence of Klebsiella quasipneumoniae subsp. similipneumoniae Strain ATCC 700603","volume":"4","author":"Elliott","year":"2016","journal-title":"Genome announcements"},{"key":"10.1016\/j.envint.2021.106466_b0105","unstructured":"Environmental Protection Agency 2016. Economic Assessment of the Waterborne Outbreak of Cryptosporidium hominis in Galway, 2007. Report No. 177. https:\/\/www.epa.ie\/pubs\/reports\/research\/water\/EPA%20-%20Research%20Report%20177_Essentra%20web.pdf."},{"key":"10.1016\/j.envint.2021.106466_b0115","unstructured":"Environmental Protection Agency 2017. Focus on Private Water Supplies. https:\/\/www.epa.ie\/pubs\/reports\/water\/drinking\/Focus%20on%20Private%20SuppliesV6.pdf."},{"key":"10.1016\/j.envint.2021.106466_b0120","unstructured":"Environmental Protection Agency 2020. Urban Waste Water Treatment in 2019. https:\/\/www.epa.ie\/pubs\/reports\/water\/wastewater\/Urban%20waste%20water%20treatment%20in%202019%20Report%20%20web%20version.pdf."},{"key":"10.1016\/j.envint.2021.106466_b0125","unstructured":"EUCAST, 2020. European Committee on Antimicrobial Susceptibility Testing Breakpoint tables for interpretation of MICs and zone diameters. Version 10.0, valid from 2020-01-01. https:\/\/eucast.org\/fileadmin\/src\/media\/PDFs\/EUCAST_files\/Breakpoint_tables\/v_10.0_Breakpoint_Tables.pdf."},{"key":"10.1016\/j.envint.2021.106466_b0130","unstructured":"European Centre for Disease Prevention and Control, 2019. Antimicrobial resistance in the EU\/EEA (EARS-NET). Annual Epidemiological Report for 2019. https:\/\/www.ecdc.europa.eu\/sites\/default\/files\/documents\/surveillance-antimicrobial-resistance-Europe-2019.pdf."},{"key":"10.1016\/j.envint.2021.106466_b0135","doi-asserted-by":"crossref","first-page":"2017","DOI":"10.1186\/s13099-017-0220-y","article-title":"Cytotoxic Escherichia coli strains encoding colibactin and cytotoxic necrotizing factor (CNF) colonize laboratory macaques","volume":"9","author":"Feng","year":"2017","journal-title":"Gut Pathog."},{"key":"10.1016\/j.envint.2021.106466_b0140","doi-asserted-by":"crossref","unstructured":"Fernando DM, Tun HM, Poole J, Patidar R, Li R, Mi R, et al. Detection of Antibiotic Resistance Genes in Source and Drinking Water Samples from a First Nations Community in Canada. 2016. Applied and Environmental Microbiology. DOI: 10.1128\/AEM.00798-16.","DOI":"10.1128\/AEM.00798-16"},{"key":"10.1016\/j.envint.2021.106466_b0145","doi-asserted-by":"crossref","first-page":"33","DOI":"10.3390\/tropicalmed5010033","article-title":"The Contribution of Wastewater to the Transmission of Antimicrobial Resistance in the Environment: Implications of Mass Gathering Settings","volume":"5","author":"Fouz","year":"2020","journal-title":"Tropical medicine and infectious disease"},{"key":"10.1016\/j.envint.2021.106466_b0150","doi-asserted-by":"crossref","first-page":"4772","DOI":"10.1128\/AEM.02898-09","article-title":"Enumeration and characterization of antimicrobial-resistant Escherichia coli bacteria in effluent from municipal, hospital, and secondary treatment facility sources","volume":"76","author":"Galvin","year":"2010","journal-title":"Appl Environ Microbiol"},{"key":"10.1016\/j.envint.2021.106466_b0155","doi-asserted-by":"crossref","unstructured":"Gij\u00f3n D, Tedim AP, Valverde A, Rodr\u00edguez I, Morosini MI, Coque TM, et al. Early OXA-48-Producing Enterobacterales Isolates Recovered in a Spanish Hospital Reveal a Complex Introduction Dominated by Sequence Type 11 (ST11) and ST405 Klebsiella Pneumoniae Clones. mSphere 2020; 5. DOI: 10.1128\/mSphere.00080-20.","DOI":"10.1128\/mSphere.00080-20"},{"key":"10.1016\/j.envint.2021.106466_b0160","doi-asserted-by":"crossref","DOI":"10.1089\/mdr.2005.11.378","article-title":"Affiliations expand The Prevalence of the OqxAB Multidrug Efflux Pump Amongst Olaquindox-Resistant Escherichia Coli in Pigs","volume":"11","author":"Hansen","year":"2005","journal-title":"Microbial drug resistance (Larchmont, N.Y.)"},{"key":"10.1016\/j.envint.2021.106466_b0165","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1016\/j.scitotenv.2018.01.100","article-title":"The prevalence of multidrug-resistant Aeromonas spp. in the municipal wastewater system and their dissemination in the environment","volume":"626","author":"Harnisz","year":"2018","journal-title":"Science of The Total Environment"},{"key":"10.1016\/j.envint.2021.106466_b0175","unstructured":"Hennessy S, Murphy H, Burns, K. Point Prevalence Survey of Healthcare-Associated Infections & Antimicrobial Use in Long-Term Care Facilities (HALT): May 2016. 2017. https:\/\/www.hpsc.ie\/a-z\/microbiologyantimicrobialresistance\/infectioncontrolandhai\/surveillance\/hcaiinlongtermcarefacilities\/haltreports\/2016report\/File,16218,en.pdf."},{"key":"10.1016\/j.envint.2021.106466_b0180","unstructured":"Health Products Regulatory Authority, 2018. Report on Consumption of Veterinary Antibiotics in Ireland during 2018. http:\/\/www.hpra.ie\/docs\/default-source\/default-document-library\/report-on-consumption-of-veterinary-antibiotics-in-ireland-during-2018.pdf?sfvrsn=0."},{"key":"10.1016\/j.envint.2021.106466_b0185","unstructured":"Health Protection Surveillance Centre, 2019a. Enhanced Surveillance of Carbapenemase-Producing Enterobacterales (CPE), 2018. https:\/\/www.hpsc.ie\/a-z\/microbiologyantimicrobialresistance\/strategyforthecontrolofantimicrobialresistanceinirelandsari\/carbapenemresistantenterobacteriaceaecre\/surveillanceofcpeinireland\/cpeannualreports\/CPE%20Enhanced%20Surveillance%20Report%202018.pdf."},{"key":"10.1016\/j.envint.2021.106466_b0190","unstructured":"Health Protection Surveillance Centre, 2019b. Hospital Antimicrobial Consumption Surveillance. https:\/\/www.hpsc.ie\/a-z\/microbiologyantimicrobialresistance\/europeansurveillanceofantimicrobialconsumptionesac\/PublicMicroB\/SACHC\/Report1.html."},{"key":"10.1016\/j.envint.2021.106466_b0195","unstructured":"Health Protection Surveillance Centre, 2019c. Annual Epidemiological Report. Cryptosporidiosis in Ireland, 2018. https:\/\/www.hpsc.ie\/a-z\/gastroenteric\/cryptosporidiosis\/publications\/epidemiologyofcryptosporidiosisinirelandannualreports\/Crypto%20Annual%20Report%202018.pdf."},{"key":"10.1016\/j.envint.2021.106466_b0200","unstructured":"Health Protection Surveillance Centre, 2019d. Annual Epidemiological Report. VTEC infection in Ireland, 2017. https:\/\/www.hpsc.ie\/a-z\/gastroenteric\/vtec\/publications\/annualreportsonepidemiologyofverotoxigenicecoli\/VTEC%20infection%20in%20Ireland%202017.pdf."},{"key":"10.1016\/j.envint.2021.106466_b0205","doi-asserted-by":"crossref","first-page":"3877","DOI":"10.1128\/JCM.01730-13","article-title":"First Outbreak of KPC-2-Producing Klebsiella pneumoniae Sequence Type 258 in a Hospital in South Korea","volume":"51","author":"Hong","year":"2013","journal-title":"J Clin Microbiol."},{"key":"10.1016\/j.envint.2021.106466_b0210","doi-asserted-by":"crossref","DOI":"10.1016\/j.watres.2020.115880","article-title":"The role of the natural aquatic environment in the dissemination of extended spectrum beta-lactamase and carbapenemase encoding genes: A scoping review","volume":"180","author":"Hooban","year":"2020","journal-title":"Water Research"},{"key":"10.1016\/j.envint.2021.106466_b0215","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1093\/jac\/dkx355","article-title":"Emergence of mcr-1 and carbapenemase genes in hospital sewage water in Beijing","volume":"73","author":"Jin","year":"2017","journal-title":"China. Journal of Antimicrobial Chemotherapy"},{"key":"10.1016\/j.envint.2021.106466_b0220","doi-asserted-by":"crossref","first-page":"1005","DOI":"10.1099\/mic.0.055459-0","article-title":"Ribosomal multilocus sequence typing: universal characterization of bacteria from domain to strain","volume":"158","author":"Jolley","year":"2012","journal-title":"Microbiology."},{"key":"10.1016\/j.envint.2021.106466_b0225","doi-asserted-by":"crossref","unstructured":"Jolley KA, Bray JE, Maiden MCJ. Open-access bacterial population genomics: BIGSdb software, the PubMLST.org website and their applications. Wellcome Open Research 2018 3:124 2018; 3. DOI: 10.12688\/wellcomeopenres.14826.1.","DOI":"10.12688\/wellcomeopenres.14826.1"},{"key":"10.1016\/j.envint.2021.106466_b0230","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0186576","article-title":"A Comparison of Extended Spectrum \u03b2-Lactamase Producing Escherichia Coli From Clinical, Recreational Water and Wastewater Samples Associated in Time and Location","volume":"12","author":"J\u00f8rgensen","year":"2017","journal-title":"PloS one"},{"key":"10.1016\/j.envint.2021.106466_b0235","doi-asserted-by":"crossref","first-page":"2023","DOI":"10.3201\/eid2312.170883","article-title":"High Rate of MCR-1\u2013Producing Escherichia coli and Klebsiella pneumoniae among Pigs","volume":"23","author":"Kieffer","year":"2017","journal-title":"Portugal. Emerging Infectious Disease journal"},{"key":"10.1016\/j.envint.2021.106466_b0240","doi-asserted-by":"crossref","unstructured":"Kittinger C, Kirschner A, Lipp M, Baumert R, Mascher F, Farnleitner AH, et al. Antibiotic Resistance of Acinetobacter spp. Isolates from the River Danube: Susceptibility Stays High. International journal of environmental research and public health 2017; 15: 52. DOI: 10.3390\/ijerph15010052.","DOI":"10.3390\/ijerph15010052"},{"key":"10.1016\/j.envint.2021.106466_b0245","doi-asserted-by":"crossref","first-page":"448","DOI":"10.1016\/j.envint.2018.12.065","article-title":"Antibiotics bioremediation: Perspectives on its ecotoxicity and resistance","volume":"124","author":"Kumar","year":"2019","journal-title":"Environment International"},{"key":"10.1016\/j.envint.2021.106466_b0250","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1016\/j.scitotenv.2017.05.174","article-title":"Contribution of bacteriophage and plasmid DNA to the mobilization of antibiotic resistance genes in a river receiving treated wastewater discharges","volume":"601\u2013602","author":"Lekunberri","year":"2017","journal-title":"Science of The Total Environment"},{"key":"10.1016\/j.envint.2021.106466_b0255","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1016\/j.envint.2017.11.003","article-title":"Exposure to and colonisation by antibiotic-resistant E. coli in UK coastal water users: Environmental surveillance, exposure assessment, and epidemiological study (Beach Bum Survey)","volume":"114","author":"Leonard","year":"2018","journal-title":"Environment International"},{"key":"10.1016\/j.envint.2021.106466_b0260","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1016\/j.jgar.2018.06.008","article-title":"Population structure of OXA-48-producing Klebsiella pneumoniae ST405 isolates during a hospital outbreak characterised by genomic typing","volume":"15","author":"L\u00f3pez-Camacho","year":"2018","journal-title":"Journal of Global Antimicrobial Resistance"},{"key":"10.1016\/j.envint.2021.106466_b0265","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijantimicag.2018.04.023","article-title":"Clonal Dissemination of Carbapenemase-Producing Klebsiella Pneumoniae: Two Distinct Sub-Lineages of Sequence Type 11 Carrying Bla KPC-2 and Bla OXA-48","volume":"52","author":"Lu","year":"2018","journal-title":"International journal of antimicrobial agents"},{"key":"10.1016\/j.envint.2021.106466_b0270","doi-asserted-by":"crossref","first-page":"20","DOI":"10.2807\/1560-7917.ES.2020.25.20.2000627","article-title":"Cross-border spread of blaNDM-1- and blaOXA-48-positive Klebsiella pneumoniae: a European collaborative analysis of whole genome sequencing and epidemiological data, 2014 to 2019","volume":"25","author":"Ludden","year":"2020","journal-title":"Eurosurveillance"},{"key":"10.1016\/j.envint.2021.106466_b0275","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.scitotenv.2019.06.480","article-title":"Detection of OXA-48-like-producing Enterobacterales in Irish recreational water","volume":"690","author":"Mahon","year":"2019","journal-title":"Science of The Total Environment"},{"key":"10.1016\/j.envint.2021.106466_b0280","doi-asserted-by":"crossref","unstructured":"Mahon, B.M., Brehony, C., McGrath, E., Killeen, J., Cormican, M., Hickey, P., et al., 2017. Indistinguishable NDM-producing Escherichia coli isolated from recreational waters, sewage, and a clinical specimen in Ireland, 2016 to 2017. Eurosurveillance 2017. DOI: 10.2807\/1560-7917.ES.2017.22.15.30513.","DOI":"10.2807\/1560-7917.ES.2017.22.15.30513"},{"key":"10.1016\/j.envint.2021.106466_b0285","doi-asserted-by":"crossref","DOI":"10.4103\/0255-0857.83907","article-title":"Development of TaqMan Real-Time Polymerase Chain Reaction for the Detection of the Newly Emerging Form of Carbapenem Resistance Gene in Clinical Isolates of Escherichia Coli, Klebsiella Pneumoniae, and Acinetobacter Baumannii","volume":"29","author":"Manchanda","year":"2011","journal-title":"Indian journal of medical microbiology"},{"key":"10.1016\/j.envint.2021.106466_b0290","article-title":"Complete Genome Assembly of Escherichia coli ATCC 25922, a Serotype O6 Reference Strain","volume":"2","author":"Minogue","year":"2014","journal-title":"Genome Announce"},{"key":"10.1016\/j.envint.2021.106466_b0295","doi-asserted-by":"crossref","DOI":"10.3389\/fmicb.2019.02961","article-title":"Core\/Whole Genome Multilocus Sequence Typing and Core Genome SNP-Based Typing of OXA-48-Producing Klebsiella pneumoniae Clinical Isolates From Spain","volume":"10","author":"Miro","year":"2020","journal-title":"Frontiers in microbiology"},{"key":"10.1016\/j.envint.2021.106466_b0300","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1016\/j.scitotenv.2016.04.075","article-title":"CapE (capture, amplify, extract): A rapid method for detection of low level contamination of water with Verocytotoxigenic Escherichia coli (VTEC)","volume":"563\u2013564","author":"Morris","year":"2016","journal-title":"Science of The Total Environment"},{"key":"10.1016\/j.envint.2021.106466_b0305","doi-asserted-by":"crossref","first-page":"4563","DOI":"10.1128\/AAC.00219-12","article-title":"Clonal Complex 258, the Most Frequently Found Multilocus Sequence Type Complex in KPC-2-Producing Klebsiella pneumoniae Isolated in Brazilian Hospitals","volume":"56","author":"Nicoletti","year":"2012","journal-title":"Antimicrob Agents Chemother."},{"key":"10.1016\/j.envint.2021.106466_b0310","unstructured":"Official Journal of the European Union. DIRECTIVE 2006\/7\/EC OF THE EUROPEAN PARLIAMENT AND OF THE COUNCIL. https:\/\/eur-lex.europa.eu\/legal-content\/EN\/TXT\/PDF\/?uri=CELEX:32006L0007&from=EN."},{"key":"10.1016\/j.envint.2021.106466_b0315","unstructured":"Official Journal of the European Communities. Directive (EU) 2020\/2184 of the European Parliament and of the Concil of 16 December 2020 on the quality of water intended for human consumption. https:\/\/eur-lex.europa.eu\/legal-content\/EN\/TXT\/PDF\/?uri=CELEX:32020L2184&from=EN."},{"key":"10.1016\/j.envint.2021.106466_b0320","doi-asserted-by":"crossref","first-page":"786","DOI":"10.1016\/j.scitotenv.2018.09.018","article-title":"The potential human exposure to antibiotic resistant-Escherichia coli through recreational water","volume":"650","author":"O'Flaherty","year":"2019","journal-title":"Sci Total Environ"},{"key":"10.1016\/j.envint.2021.106466_b0325","doi-asserted-by":"crossref","DOI":"10.1093\/jac\/dks383","article-title":"Emergence of OXA-48-producing Klebsiella Pneumoniae and the Novel Carbapenemases OXA-244 and OXA-245 in Spain","volume":"68","author":"Oteo","year":"2013","journal-title":"The Journal of antimicrobial chemotherapy"},{"key":"10.1016\/j.envint.2021.106466_b0330","first-page":"593","article-title":"Modelling of Escherichia Coli Concentrations in Bathing Water at Microtidal Coasts","author":"Palaz\u00f3n","year":"2017","journal-title":"The Science of the total environment"},{"key":"10.1016\/j.envint.2021.106466_b0335","doi-asserted-by":"crossref","DOI":"10.1128\/AAC.01963-17","article-title":"Concentration and Variety of Carbapenemase Producers in Recreational Coastal Waters Showing Distinct Levels of Pollution","volume":"61","author":"Paschoal","year":"2017","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.envint.2021.106466_b0340","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2019.134023","article-title":"Antibiotic resistance genes identified in wastewater treatment plant systems \u2013 A review","volume":"697","author":"Pazda","year":"2019","journal-title":"Science of The Total Environment"},{"key":"10.1016\/j.envint.2021.106466_b0345","doi-asserted-by":"crossref","first-page":"24","DOI":"10.3389\/fmicb.2012.00024","article-title":"Plasmid-Mediated Quinolone Resistance; Interactions between Human, Animal, and Environmental Ecologies","volume":"3","author":"Poirel","year":"2012","journal-title":"Frontiers in Microbiology"},{"key":"10.1016\/j.envint.2021.106466_b0350","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1179\/2047773215Y.0000000030","article-title":"Antimicrobial resistance: a global multifaceted phenomenon","volume":"109","author":"Prestinaci","year":"2015","journal-title":"Pathogens and global health"},{"key":"10.1016\/j.envint.2021.106466_b0355","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1111\/j.1574-6976.2001.tb00589.x","article-title":"Survival of enteric bacteria in seawater","volume":"25","author":"Rozen","year":"2001","journal-title":"FEMS Microbiology Reviews"},{"key":"10.1016\/j.envint.2021.106466_b0360","doi-asserted-by":"crossref","first-page":"1083","DOI":"10.1111\/j.1469-0691.2008.02093.x","article-title":"Distribution of genes encoding iron uptake systems among enteroaggregative Escherichia coli strains isolated from adults with irritable bowel syndrome","volume":"14","author":"Sobieszcza\u0144ska","year":"2008","journal-title":"Clinical Microbiology and Infection"},{"key":"10.1016\/j.envint.2021.106466_b0365","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1111\/j.1365-2672.2008.03960.x","article-title":"A conjugative macrolide resistance gene, mef(A), in environmental Clostridium perfringens carrying multiple macrolide and\/or tetracycline resistance genes","volume":"106","author":"Soge","year":"2009","journal-title":"J Appl Microbiol"},{"key":"10.1016\/j.envint.2021.106466_b0370","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/j.ijantimicag.2011.03.010","article-title":"Real-time TaqMan PCR for rapid detection of genes encoding five types of non-metallo- (class A and D) carbapenemases in Enterobacteriaceae","volume":"38","author":"Swayne","year":"2011","journal-title":"International Journal of Antimicrobial Agents"},{"key":"10.1016\/j.envint.2021.106466_b0375","doi-asserted-by":"crossref","unstructured":"Turton JF, Payne Z, Coward A, Hopkins KL, Turton JA, Doumith M, et al. Virulence Genes in Isolates of Klebsiella Pneumoniae From the UK During 2016, Including Among Carbapenemase Gene-Positive Hypervirulent K1-ST23 and 'Non-Hypervirulent' Types ST147, ST15 and ST383. Journal of medical microbiology 2018; 67. DOI: 10.1099\/jmm.0.000653.","DOI":"10.1099\/jmm.0.000653"},{"key":"10.1016\/j.envint.2021.106466_b0380","article-title":"Outbreak of OXA-48 Carbapenemase-Producing Klebsiella Pneumoniae in Greece Involving an ST11 Clone","volume":"68","author":"Voulgari","year":"2012","journal-title":"The Journal of antimicrobial chemotherapy"},{"key":"10.1016\/j.envint.2021.106466_b0385","unstructured":"World Health Organization, 2015. Global Action Plan on Antimicrobial Resistance. https:\/\/apps.who.int\/iris\/bitstream\/handle\/10665\/193736\/9789241509763_eng.pdf?sequence=1."},{"key":"10.1016\/j.envint.2021.106466_b0390","unstructured":"World Health Organization, 2017. GLOBAL PRIORITY LIST OF ANTIBIOTIC-RESISTANT BACTERIA TO GUIDE RESEARCH, DISCOVERY, AND DEVELOPMENT OF NEW ANTIBIOTICS. https:\/\/www.who.int\/medicines\/publications\/WHO-PPL-Short_Summary_25Feb-ET_NM_WHO.pdf."},{"key":"10.1016\/j.envint.2021.106466_b0395","doi-asserted-by":"crossref","DOI":"10.1016\/j.wroa.2018.10.003","article-title":"Within-day variability in microbial concentrations at a UK designated bathing water: Implications for regulatory monitoring and the application of predictive modelling based on historical compliance data","volume":"1","author":"Wyer","year":"2018","journal-title":"Water research X"},{"key":"10.1016\/j.envint.2021.106466_b0400","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1111\/j.1472-765X.2011.03016.x","article-title":"Identification of a novel fosfomycin resistance gene (fosA2) in Enterobacter cloacae from the Salmon River","volume":"52","author":"Xu","year":"2011","journal-title":"Canada. Lett Appl Microbiol"},{"issue":"5","key":"10.1016\/j.envint.2021.106466_b0405","doi-asserted-by":"crossref","first-page":"821","DOI":"10.1101\/gr.074492.107","article-title":"Velvet: algorithms for de novo short read assembly using de Bruijn graphs","volume":"18","author":"Zerbino and Birney","year":"2008","journal-title":"Genome Research."},{"key":"10.1016\/j.envint.2021.106466_b0410","doi-asserted-by":"crossref","first-page":"1183","DOI":"10.3390\/ijerph17041183","article-title":"The Prevalence and Characterization of Extended-Spectrum \u03b2-Lactamase- and Carbapenemase-Producing Bacteria from Hospital Sewage, Treated Effluents and Receiving Rivers","volume":"17","author":"Zhang","year":"2020","journal-title":"International Journal of Environmental Research and Public Health"},{"key":"10.1016\/j.envint.2021.106466_b0415","doi-asserted-by":"crossref","first-page":"1395","DOI":"10.1101\/gr.232397.117","article-title":"GrapeTree: visualization of core genomic relationships among 100,000 bacterial pathogens","volume":"28","author":"Zhou","year":"2018","journal-title":"Genome research"},{"key":"10.1016\/j.envint.2021.106466_b0420","doi-asserted-by":"crossref","first-page":"334","DOI":"10.3389\/fmicb.2020.00334","article-title":"Emergence of NDM-5-Producing Escherichia coli in a Teaching Hospital in Chongqing, China: IncF-Type Plasmids May Contribute to the Prevalence of blaNDM\u20135","volume":"11","author":"Zou","year":"2020","journal-title":"Frontiers in Microbiology"}],"container-title":["Environment International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S016041202100091X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S016041202100091X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,27]],"date-time":"2025-09-27T12:08:00Z","timestamp":1758974880000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S016041202100091X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,7]]},"references-count":82,"alternative-id":["S016041202100091X"],"URL":"https:\/\/doi.org\/10.1016\/j.envint.2021.106466","relation":{},"ISSN":["0160-4120"],"issn-type":[{"value":"0160-4120","type":"print"}],"subject":[],"published":{"date-parts":[[2021,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A Point Prevalence Survey of Antibiotic Resistance in the Irish Environment, 2018\u20132019","name":"articletitle","label":"Article Title"},{"value":"Environment International","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.envint.2021.106466","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 The Author(s). Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}],"article-number":"106466"}}