{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T10:43:17Z","timestamp":1790678597452,"version":"4.1.0"},"reference-count":54,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,7,1]],"date-time":"2021-07-01T00:00:00Z","timestamp":1625097600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,7,1]],"date-time":"2021-07-01T00:00:00Z","timestamp":1625097600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,2,22]],"date-time":"2021-02-22T00:00:00Z","timestamp":1613952000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Environment International"],"published-print":{"date-parts":[[2021,7]]},"DOI":"10.1016\/j.envint.2021.106481","type":"journal-article","created":{"date-parts":[[2021,3,8]],"date-time":"2021-03-08T23:41:43Z","timestamp":1615246903000},"page":"106481","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":76,"special_numbering":"C","title":["Hair versus urine for the biomonitoring of pesticide exposure: Results from a pilot cohort study on pregnant women"],"prefix":"10.1016","volume":"152","author":[{"given":"Emilie M.","family":"Hardy","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cl\u00e9mentine","family":"Dereumeaux","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laurence","family":"Guldner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olivier","family":"Briand","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"St\u00e9phanie","family":"Vandentorren","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amivi","family":"Oleko","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C\u00e9cile","family":"Zaros","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brice M.R.","family":"Appenzeller","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.envint.2021.106481_b0005","doi-asserted-by":"crossref","first-page":"1189","DOI":"10.1289\/ehp.1003185","article-title":"Prenatal Exposure to Organophosphate Pesticides and IQ in 7-Year-Old Children","volume":"119","author":"Bouchard","year":"2011","journal-title":"Environ. Health Perspec."},{"key":"10.1016\/j.envint.2021.106481_b0010","doi-asserted-by":"crossref","first-page":"1182","DOI":"10.1289\/ehp.1003183","article-title":"Prenatal Exposure to Organophosphates, Paraoxonase 1, and Cognitive Development in Childhood","volume":"119","author":"Engel","year":"2011","journal-title":"Environ. Health Perspec."},{"key":"10.1016\/j.envint.2021.106481_b0015","doi-asserted-by":"crossref","first-page":"1378","DOI":"10.1289\/ehp.1306667","article-title":"Urinary metabolites of organophosphate and pyrethroid pesticides and behavioral problems in Canadian children","volume":"121","author":"Oulhote","year":"2013","journal-title":"Environ. Health Perspec."},{"key":"10.1016\/j.envint.2021.106481_b0020","doi-asserted-by":"crossref","first-page":"1196","DOI":"10.1289\/ehp.1003160","article-title":"Seven-Year Neurodevelopmental Scores and Prenatal Exposure to Chlorpyrifos, a Common Agricultural Pesticide","volume":"119","author":"Rauh","year":"2011","journal-title":"Environ. Health Perspec."},{"key":"10.1016\/j.envint.2021.106481_b0025","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/j.envint.2015.05.009","article-title":"Pyrethroid insecticide exposure and cognitive developmental disabilities in children: The PELAGIE mother\u2013child cohort","volume":"82","author":"Viel","year":"2015","journal-title":"Environ. Int."},{"key":"10.1016\/j.envint.2021.106481_b0030","doi-asserted-by":"crossref","first-page":"856","DOI":"10.1289\/ehp.0901568","article-title":"Comparison of current-use pesticide and other toxicant urinary metabolites levels among pregnant women in the CHAMACOS cohort and NHANES","volume":"118","author":"Castorina","year":"2010","journal-title":"Environ. Health Perspec."},{"key":"10.1016\/j.envint.2021.106481_b0035","doi-asserted-by":"crossref","first-page":"1802","DOI":"10.1289\/ehp.7894","article-title":"Organophosphate Urinary Metabolite Levels during Pregnancy and after Delivery in Women Living in an Agricultural Community","volume":"113","author":"Bradman","year":"2005","journal-title":"Environ. Health Perspec."},{"key":"10.1016\/j.envint.2021.106481_b0040","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1016\/j.envint.2010.09.002","article-title":"Pesticide exposure among pregnant women in Jerusalem, Israel: results of a pilot study","volume":"37","author":"Berman","year":"2011","journal-title":"Environ. Int."},{"issue":"2","key":"10.1016\/j.envint.2021.106481_b0045","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1289\/ehp.1103743","article-title":"Serum concentrations of organochlorine pesticides and growth among Russian boys","volume":"120","author":"Burns","year":"2012","journal-title":"Environ. Health Perspec."},{"key":"10.1016\/j.envint.2021.106481_b0050","doi-asserted-by":"crossref","first-page":"1204","DOI":"10.1289\/ehp.10184","article-title":"Association between serum concentrations or persistent organic pollutants and self-reported cardiovascular disease prevalence: results from National Health and Nutrition Examination Survey, 1999\u20132002","volume":"115","author":"Ha","year":"2007","journal-title":"Environ. Health Perspec."},{"key":"10.1016\/j.envint.2021.106481_b0055","doi-asserted-by":"crossref","first-page":"1841","DOI":"10.1007\/s00125-007-0755-4","article-title":"Relationship between serum concentrations of persistent organic pollutants and the prevalence of metabolic syndrome among non-diabetic adults: results from the National Health and Nutrition Examination Survey 1999\u20132002","volume":"50","author":"Lee","year":"2007","journal-title":"Diabetologia"},{"issue":"7","key":"10.1016\/j.envint.2021.106481_b0060","doi-asserted-by":"crossref","first-page":"1638","DOI":"10.2337\/dc06-0543","article-title":"A strong dose-response relation between serum concentrations of persistent organic pollutants and diabtes","volume":"29","author":"Lee","year":"2006","journal-title":"Diabet. Care"},{"key":"10.1016\/j.envint.2021.106481_b0065","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1016\/j.envres.2014.07.024","article-title":"Organochlorine chemicals and neurodegeneration among elderly subjects in Costa Rica","volume":"134","author":"Steenland","year":"2014","journal-title":"Environ. Res."},{"issue":"1","key":"10.1016\/j.envint.2021.106481_b0070","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0116057","article-title":"Persistent Organic Pollutants and Early Menopause in U.S. Women","volume":"10","author":"Grindler","year":"2015","journal-title":"PLoS ONE"},{"key":"10.1016\/j.envint.2021.106481_b0075","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1016\/j.envint.2006.04.002","article-title":"Organohalogenated pollutants in human serum from Iassy, Romania and their relation with age and gender","volume":"32","author":"Dirtu","year":"2006","journal-title":"Environ. Int."},{"issue":"6","key":"10.1016\/j.envint.2021.106481_b0080","doi-asserted-by":"crossref","first-page":"878","DOI":"10.1289\/ehp.1002727","article-title":"Environmental chemicals in pregnant women in the United States: NHANES 2003\u20132004","volume":"119","author":"Woodruff","year":"2011","journal-title":"Environ. Health Perspec."},{"key":"10.1016\/j.envint.2021.106481_b0085","doi-asserted-by":"crossref","first-page":"818","DOI":"10.1016\/j.scitotenv.2013.10.048","article-title":"Plasma concentrations of persistent organic pollutants in the Cree of northern Quebec, Canada: Results from the multi-community environment-and-health study","volume":"470\u2013471","author":"Liberda","year":"2014","journal-title":"Sci. Tot. Environ."},{"issue":"33","key":"10.1016\/j.envint.2021.106481_b0090","doi-asserted-by":"crossref","first-page":"40971","DOI":"10.1007\/s11356-019-05686-x","article-title":"Prenatal and childhood exposure to chlordecone and sex-typed toy preference of 7-year-old Guadeloupean children","volume":"27","author":"Cordier","year":"2020","journal-title":"Environ. Sci. Pollut. Res. Int."},{"issue":"1","key":"10.1016\/j.envint.2021.106481_b0095","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1016\/j.ijheh.2019.10.010","article-title":"Multiple pesticides in mothers' hair samples and children's measurements at birth: Results from the French national birth cohort (ELFE)","volume":"223","author":"Beranger","year":"2020","journal-title":"Int. J. Hygiene Environ. Health"},{"key":"10.1016\/j.envint.2021.106481_b0100","unstructured":"Centers for Diseases Control and Prevention, Fourth National Report on Human Exposure to Environmental Chemicals. Department of Health and Human Services Centers for Disease Control and Prevention 2019."},{"key":"10.1016\/j.envint.2021.106481_b0105","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/j.envres.2014.07.012","article-title":"Biomonitoring of dialkylphosphate metabolites (DAPs) in urine and hair samples of sprayers and rural residents of Crete Greece","volume":"134","author":"Kokkinaki","year":"2014","journal-title":"Environ. Res."},{"issue":"2","key":"10.1016\/j.envint.2021.106481_b0110","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/j.toxlet.2011.10.021","article-title":"Hair analysis for biomonitoring of environmental and occupational exposure to organic pollutants: State of the art, critical review and future needs","volume":"210","author":"Appenzeller","year":"2012","journal-title":"Toxicol. Lett."},{"key":"10.1016\/j.envint.2021.106481_b0115","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.envint.2020.105633","article-title":"Exposure to multiclass pesticides among female adult population in two Chinese cities revealed by hair analysis","volume":"138","author":"Peng","year":"2020","journal-title":"Environ. Int."},{"key":"10.1016\/j.envint.2021.106481_b0120","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1016\/j.envint.2017.10.025","article-title":"Assessment of human exposure to pesticides by hair analysis: The case of vegetable-producing areas in Burkina Faso","volume":"111","author":"Lehmann","year":"2018","journal-title":"Environ. Int."},{"key":"10.1016\/j.envint.2021.106481_b0125","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2019.105332","article-title":"Cumulative exposure to organic pollutants of French children assessed by hair analysis","volume":"134","author":"Iglesias-Gonz\u00e1lez","year":"2020","journal-title":"Environ. Int."},{"key":"10.1016\/j.envint.2021.106481_b0130","doi-asserted-by":"crossref","first-page":"864","DOI":"10.1016\/j.scitotenv.2019.02.177","article-title":"Biomonitoring of children exposure to urban pollution and environmental tobacco smoke with hair analysis \u2013 A pilot study on children living in Paris and Yeu Island France","volume":"665","author":"Palazzi","year":"2019","journal-title":"Sci. Tot. Environ."},{"key":"10.1016\/j.envint.2021.106481_b0135","doi-asserted-by":"crossref","first-page":"438","DOI":"10.1016\/j.envint.2008.09.003","article-title":"Non-invasive matrices in human biomonitoring: a review","volume":"35","author":"Esteban","year":"2009","journal-title":"Environ. Int."},{"issue":"3","key":"10.1016\/j.envint.2021.106481_b0140","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1089\/bio.2010.0032","article-title":"A Pilot Study of the ELFE Longitudinal Cohort: Feasibility and Preliminary Evaluation of Biological Collection","volume":"9","author":"Oleko","year":"2011","journal-title":"Biopreservat. Biobanking"},{"key":"10.1016\/j.envint.2021.106481_b0145","first-page":"6","article-title":"Multi-residue analysis of organic pollutants in hair and urine for matrices comparison","volume":"249C","author":"Hardy","year":"2014","journal-title":"Forensic Sci. Int."},{"key":"10.1016\/j.envint.2021.106481_b0150","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1002\/dta.1649","article-title":"Hair decontamination procedure prior to multi-class pesticide analysis","volume":"6","author":"Duca","year":"2014","journal-title":"Drug Testing Anal"},{"key":"10.1016\/j.envint.2021.106481_b0155","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/0379-0738(93)90255-9","article-title":"Anatomy and physiology of hair","volume":"63","author":"Harkey","year":"1993","journal-title":"Forensic Sci. Int."},{"key":"10.1016\/j.envint.2021.106481_b0160","doi-asserted-by":"crossref","first-page":"2434","DOI":"10.1016\/j.chemosphere.2006.04.051","article-title":"Fabricating data: How substituting values for nondetects can ruin results, and what can be done about it","volume":"65","author":"Helsel","year":"2006","journal-title":"Chemosphere"},{"key":"10.1016\/j.envint.2021.106481_b0165","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/j.envint.2018.07.023","article-title":"Multiple pesticide analysis in hair samples of pregnant French women: results from the Elfe national birth cohort","volume":"120","author":"Beranger","year":"2018","journal-title":"Environ. Int"},{"key":"10.1016\/j.envint.2021.106481_b0170","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/j.aca.2011.10.029","article-title":"Multi-class pesticide analysis in human hair by gas chromatography tandem (triple quadrupole) mass spectrometry with solid phase microextraction and liquid injection","volume":"710","author":"Salquebre","year":"2012","journal-title":"Anal. Chim. Acta"},{"issue":"2","key":"10.1016\/j.envint.2021.106481_b0175","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1016\/j.toxlet.2011.11.019","article-title":"Determination of farm workers' exposure to pesticides by hair analysis","volume":"210","author":"Schummer","year":"2012","journal-title":"Toxicol. Lett."},{"issue":"8","key":"10.1016\/j.envint.2021.106481_b0180","doi-asserted-by":"crossref","first-page":"975","DOI":"10.1016\/j.chemosphere.2012.06.056","article-title":"Persistent organochlorine contaminants in hair samples of Northern Poland population, 1968\u20132009","volume":"89","author":"Wielgomas","year":"2012","journal-title":"Chemosphere"},{"issue":"1","key":"10.1016\/j.envint.2021.106481_b0185","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/j.forsciint.2007.07.017","article-title":"Pesticide levels in head hair samples of Cretan population as an indicator of present and past exposure","volume":"176","author":"Tsatsakis","year":"2008","journal-title":"Forensic Sci. Int."},{"issue":"12","key":"10.1016\/j.envint.2021.106481_b0190","doi-asserted-by":"crossref","first-page":"933","DOI":"10.1177\/0960327108102047","article-title":"Assessment of levels of organochlorine pesticides and their metabolites in the hair of a Greek rural human population","volume":"27","author":"Tsatsakis","year":"2008","journal-title":"Human Experim. Toxicol."},{"issue":"1","key":"10.1016\/j.envint.2021.106481_b0195","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/j.chemosphere.2008.02.058","article-title":"Organochlorine contaminants in hair of adolescents from Iassy Romania","volume":"72","author":"Covaci","year":"2008","journal-title":"Chemosphere"},{"key":"10.1016\/j.envint.2021.106481_b0200","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1016\/j.envint.2019.104997","article-title":"Biomonitoring of common organophosphate metabolites in hair and urine of children from an agricultural community","volume":"131","author":"Hernandez","year":"2019","journal-title":"Environ. Int."},{"issue":"4","key":"10.1016\/j.envint.2021.106481_b0205","first-page":"441","article-title":"Exposure of the French population to environmental chemicals ENNS 2006\u20132007 study","volume":"29","author":"Frery","year":"2017","journal-title":"Toxicologie Analytique Et Clinique"},{"issue":"2","key":"10.1016\/j.envint.2021.106481_b0210","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1016\/j.envres.2008.07.014","article-title":"Urinary metabolite concentrations of organophosphorous pesticides, bisphenol A, and phthalates among pregnant women in Rotterdam, the Netherlands: The Generation R study","volume":"108","author":"Ye","year":"2008","journal-title":"Environ. Res."},{"key":"10.1016\/j.envint.2021.106481_b0215","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/j.envint.2018.04.042","article-title":"Urinary levels of pyrethroid pesticides and determinants in pregnant French women from the Elfe cohort","volume":"119","author":"Dereumeaux","year":"2018","journal-title":"Environ. Int."},{"issue":"8","key":"10.1016\/j.envint.2021.106481_b0220","doi-asserted-by":"crossref","first-page":"2813","DOI":"10.1007\/s00204-016-1910-9","article-title":"Hair analysis for the biomonitoring of pesticide exposure: comparison with blood and urine in a rat model","volume":"91","author":"Appenzeller","year":"2017","journal-title":"Arch. Toxicol."},{"key":"10.1016\/j.envint.2021.106481_b0225","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/j.envpol.2019.02.017","article-title":"Perfluoroalkyl acids in paired serum, urine, and hair samples: Correlations with demographic factors and dietary habits","volume":"248","author":"Kim","year":"2019","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.envint.2021.106481_b0230","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/j.jes.2017.08.017","article-title":"Occurrence of perfluoroalkyl substances in matched human serum, urine, hair and nail","volume":"67","author":"Wang","year":"2018","journal-title":"J. Environ. Sci."},{"key":"10.1016\/j.envint.2021.106481_b0235","doi-asserted-by":"crossref","first-page":"3601","DOI":"10.1007\/s00216-016-9442-y","article-title":"Influence of pesticide physicochemical properties on the association between plasma and hair concentration","volume":"408","author":"Chata","year":"2016","journal-title":"Anal. Bioanal. Chem."},{"key":"10.1016\/j.envint.2021.106481_b0240","doi-asserted-by":"crossref","first-page":"2849","DOI":"10.1007\/s00204-019-02546-y","article-title":"Pharmacokinetic parameters of 17 common pesticides in mixture following oral exposure in Long Evans female rat: A realistic human exposure","volume":"93","author":"Chata","year":"2019","journal-title":"Arch. Toxicol."},{"issue":"141185","key":"10.1016\/j.envint.2021.106481_b0245","article-title":"Is there an optimal sampling time and number of samples for assessing exposure to 1 fast elimination endocrine disruptors with urinary biomarkers?","volume":"747","author":"Fa\u00ffs","year":"2020","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.envint.2021.106481_b0250","doi-asserted-by":"crossref","unstructured":"Ettlinger, J., L. Kirchen, and M. Yegles, Influence of thermal hair straightening on ethyl glucuronide content in hair. Drug Test Anal, 2014. 6 Suppl 1: p. 74-7.","DOI":"10.1002\/dta.1648"},{"key":"10.1016\/j.envint.2021.106481_b0255","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1016\/j.forsciint.2019.02.030","article-title":"Influence of cosmetic hair treatments on cannabinoids in hair: Bleaching, perming and permanent coloring","volume":"297","author":"Van Elsu\u00e9","year":"2019","journal-title":"Forensic Sci. Int."},{"key":"10.1016\/j.envint.2021.106481_b0260","doi-asserted-by":"crossref","DOI":"10.1016\/j.forsciint.2019.109894","article-title":"AEME production in cocaine positive hair after thermal hair treatment","volume":"302","author":"Gambier","year":"2019","journal-title":"Forensic Sci. Int."},{"issue":"3","key":"10.1016\/j.envint.2021.106481_b0265","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1038\/sj.jea.7500402","article-title":"Temporal variability of urinary levels of nonpersistent insecticides in adult men","volume":"15","author":"Meeker","year":"2005","journal-title":"J. Expo. Anal. Environ. Epidemiol."},{"issue":"2","key":"10.1016\/j.envint.2021.106481_b0270","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1289\/ehp.1306737","article-title":"Within- and between-child variation in repeated urinary pesticide metabolite measurements over a 1-year period","volume":"122","author":"Attflied","year":"2014","journal-title":"Environ. Health Perspec."}],"container-title":["Environment International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0160412021001069?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0160412021001069?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,27]],"date-time":"2025-09-27T12:08:07Z","timestamp":1758974887000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0160412021001069"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,7]]},"references-count":54,"alternative-id":["S0160412021001069"],"URL":"https:\/\/doi.org\/10.1016\/j.envint.2021.106481","relation":{},"ISSN":["0160-4120"],"issn-type":[{"value":"0160-4120","type":"print"}],"subject":[],"published":{"date-parts":[[2021,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Hair versus urine for the biomonitoring of pesticide exposure: Results from a pilot cohort study on pregnant women","name":"articletitle","label":"Article Title"},{"value":"Environment International","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.envint.2021.106481","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 The Author(s). Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}],"article-number":"106481"}}