{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T06:19:00Z","timestamp":1789021140280,"version":"build-2803163510"},"reference-count":32,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,10,25]],"date-time":"2022-10-25T00:00:00Z","timestamp":1666656000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Environment International"],"published-print":{"date-parts":[[2022,12]]},"DOI":"10.1016\/j.envint.2022.107603","type":"journal-article","created":{"date-parts":[[2022,10,26]],"date-time":"2022-10-26T11:40:54Z","timestamp":1666784454000},"page":"107603","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":35,"special_numbering":"C","title":["Exploring oxidative stress and endothelial dysfunction as a mechanism linking bisphenol S exposure to vascular disease in human umbilical vein endothelial cells and a mouse model of postnatal exposure"],"prefix":"10.1016","volume":"170","author":[{"given":"Sarah","family":"Easson","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Radha Dutt","family":"Singh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liam","family":"Connors","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Taylor","family":"Scheidl","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Larissa","family":"Baker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anshul","family":"Jadli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hai-Lei","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer","family":"Thompson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.envint.2022.107603_b0005","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1289\/ehp.10753","article-title":"Exposure of the U.S. population to bisphenol A and 4-tertiary-octylphenol: 2003\u20132004","volume":"116","author":"Calafat","year":"2008","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.envint.2022.107603_b0010","article-title":"Plasticizers and Cardiovascular Health: Role of Adipose Tissue Dysfunction","volume":"11","author":"Callaghan","year":"2020","journal-title":"Front. Pharmacol."},{"issue":"11","key":"10.1016\/j.envint.2022.107603_b0015","doi-asserted-by":"crossref","first-page":"5438","DOI":"10.1021\/acs.est.5b05387","article-title":"Bisphenol Analogues Other Than BPA: Environmental Occurrence, Human Exposure, and Toxicity-A Review","volume":"50","author":"Chen","year":"2016","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.envint.2022.107603_b9000","doi-asserted-by":"crossref","DOI":"10.3389\/ftox.2022.933572","article-title":"Prenatal exposure to a low dose of BPS causes sex-dependent alterations to vascular endothelial dysfunction in adult offspring","author":"Connors","year":"2022","journal-title":"Front. Toxicol."},{"issue":"6","key":"10.1016\/j.envint.2022.107603_b0020","doi-asserted-by":"crossref","first-page":"923","DOI":"10.1007\/s00424-010-0808-2","article-title":"Nitric oxide and oxidative stress in vascular disease","volume":"459","author":"F\u00f6rstermann","year":"2010","journal-title":"Pflugers Arch."},{"issue":"7","key":"10.1016\/j.envint.2022.107603_b0025","doi-asserted-by":"crossref","first-page":"829","DOI":"10.1093\/eurheartj\/ehr304","article-title":"Nitric oxide synthases: regulation and function","volume":"33","author":"Forstermann","year":"2012","journal-title":"Eur. Heart J."},{"key":"10.1016\/j.envint.2022.107603_b0030","doi-asserted-by":"crossref","unstructured":"Genuis, S.J., Beesoon, S., Birkholz, D., Lobo, R.A., 2012. Human excretion of bisphenol A: blood, urine, and sweat (BUS) study. J. Environ. Public Health. 2012, 185731.","DOI":"10.1155\/2012\/185731"},{"issue":"8","key":"10.1016\/j.envint.2022.107603_b0035","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1161\/01.RES.87.8.677","article-title":"Membrane estrogen receptor engagement activates endothelial nitric oxide synthase via the PI3-kinase-Akt pathway in human endothelial cells","volume":"87","author":"Haynes","year":"2000","journal-title":"Circ. Res."},{"key":"10.1016\/j.envint.2022.107603_b0040","doi-asserted-by":"crossref","first-page":"113639","DOI":"10.1016\/j.envpol.2019.113639","article-title":"Association of bisphenol A and its alternatives bisphenol S and F exposure with hypertension and blood pressure: A cross-sectional study in China","volume":"257","author":"Jiang","year":"2020","journal-title":"Environ. Pollut."},{"issue":"10119","key":"10.1016\/j.envint.2022.107603_b0045","doi-asserted-by":"crossref","first-page":"462","DOI":"10.1016\/S0140-6736(17)32345-0","article-title":"The Lancet Commission on pollution and health","volume":"391","author":"Landrigan","year":"2018","journal-title":"Lancet"},{"issue":"19","key":"10.1016\/j.envint.2022.107603_b0050","doi-asserted-by":"crossref","first-page":"4655","DOI":"10.1021\/jf400445n","article-title":"Concentrations and profiles of bisphenol A and other bisphenol analogues in foodstuffs from the United States and their implications for human exposure","volume":"61","author":"Liao","year":"2013","journal-title":"J. Agric. Food Chem."},{"issue":"12","key":"10.1016\/j.envint.2022.107603_b0055","doi-asserted-by":"crossref","first-page":"6860","DOI":"10.1021\/es301334j","article-title":"Bisphenol S in urine from the United States and seven Asian countries: occurrence and human exposures","volume":"46","author":"Liao","year":"2012","journal-title":"Environ. Sci. Technol."},{"issue":"1","key":"10.1016\/j.envint.2022.107603_b0060","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1016\/j.atherosclerosis.2011.05.001","article-title":"Circulating levels of bisphenol A and phthalates are related to carotid atherosclerosis in the elderly","volume":"218","author":"Lind","year":"2011","journal-title":"Atherosclerosis."},{"key":"10.1016\/j.envint.2022.107603_b0065","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1016\/j.envint.2018.07.001","article-title":"Exposure and dietary sources of bisphenol A (BPA) and BPA-alternatives among mothers in the APrON cohort study","volume":"119","author":"Liu","year":"2018","journal-title":"Environ. Int."},{"issue":"20","key":"10.1016\/j.envint.2022.107603_b0070","doi-asserted-by":"crossref","first-page":"1881","DOI":"10.1056\/NEJMra2030281","article-title":"Pollution and the Heart","volume":"385","author":"Longo","year":"2021","journal-title":"N. Engl. J. Med."},{"issue":"2","key":"10.1016\/j.envint.2022.107603_b0075","first-page":"209","article-title":"Bisphenol A - Application, sources of exposure and potential risks in infants, children and pregnant women","volume":"28","author":"Miko\u0142ajewska","year":"2015","journal-title":"Int. J. Occup. Med. Environ. Health"},{"key":"10.1016\/j.envint.2022.107603_b0080","doi-asserted-by":"crossref","first-page":"142941","DOI":"10.1016\/j.scitotenv.2020.142941","article-title":"Effects of bisphenol A on cardiovascular disease: An epidemiological study using National Health and Nutrition Examination Survey 2003\u20132016 and meta-analysis","volume":"763","author":"Moon","year":"2021","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.envint.2022.107603_b0085","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/j.mce.2016.10.003","article-title":"Environmental estrogen-like endocrine disrupting chemicals and breast cancer","volume":"457","author":"Morgan","year":"2017","journal-title":"Mol. Cell. Endocrinol."},{"key":"10.1016\/j.envint.2022.107603_b0090","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1016\/j.freeradbiomed.2015.11.013","article-title":"Therapeutic inhibition of mitochondrial reactive oxygen species with mito-TEMPO reduces diabetic cardiomyopathy","volume":"90","author":"Ni","year":"2016","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.envint.2022.107603_b0095","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/j.brainres.2007.08.036","article-title":"Estrogen suppresses brain mitochondrial oxidative stress in female and male rats","volume":"1176","author":"Razmara","year":"2007","journal-title":"Brain Res."},{"issue":"6","key":"10.1016\/j.envint.2022.107603_b0100","doi-asserted-by":"crossref","first-page":"472","DOI":"10.1177\/1479164113500680","article-title":"Cellular and molecular mechanisms of endothelial dysfunction in diabetes","volume":"10","author":"Roberts","year":"2013","journal-title":"Diab. Vasc. Dis. Res."},{"issue":"13","key":"10.1016\/j.envint.2022.107603_b0105","doi-asserted-by":"crossref","first-page":"7001","DOI":"10.3390\/ijerph18137001","article-title":"What Does CLARITY-BPA Mean for Canadians?","volume":"18","author":"Rogers","year":"2021","journal-title":"Int. J. Environ. Res. Public Health"},{"issue":"11","key":"10.1016\/j.envint.2022.107603_b0110","doi-asserted-by":"crossref","first-page":"4719","DOI":"10.1096\/fj.14-252460","article-title":"Oral administration of bisphenol A induces high blood pressure through angiotensin II\/CaMKII-dependent uncoupling of eNOS","volume":"28","author":"Saura","year":"2014","journal-title":"FASEB J."},{"key":"10.1016\/j.envint.2022.107603_b0115","doi-asserted-by":"crossref","unstructured":"Shankar, A., Teppala, S., 2012. Urinary bisphenol A and hypertension in a multiethnic sample of US adults. J. Environ. Public Health, 2012, 481641.","DOI":"10.1155\/2012\/481641"},{"issue":"9","key":"10.1016\/j.envint.2022.107603_b0120","doi-asserted-by":"crossref","first-page":"1297","DOI":"10.1289\/ehp.1104114","article-title":"Bisphenol A and peripheral arterial disease: results from the NHANES","volume":"120","author":"Shankar","year":"2012","journal-title":"Environ. Health Perspect."},{"issue":"Pt B","key":"10.1016\/j.envint.2022.107603_b0125","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1016\/j.fct.2016.10.028","article-title":"To which chemical mixtures is the French population exposed? Mixture identification from the second French Total Diet Study","volume":"98","author":"Traor\u00e9","year":"2016","journal-title":"Food Chem. Toxicol."},{"issue":"1","key":"10.1016\/j.envint.2022.107603_b0130","doi-asserted-by":"crossref","DOI":"10.1186\/s12302-021-00586-9","article-title":"The bisphenol F and bisphenol S and cardiovascular disease: results from NHANES 2013\u20132016","volume":"34","author":"Wang","year":"2022","journal-title":"Environ. Sci. Eur."},{"key":"10.1016\/j.envint.2022.107603_b0135","doi-asserted-by":"crossref","first-page":"113734","DOI":"10.1016\/j.envres.2022.113734","article-title":"Human health risk assessment of bisphenol A (BPA) through meat products","volume":"213","author":"Wang","year":"2022","journal-title":"Environ. Res."},{"issue":"3","key":"10.1016\/j.envint.2022.107603_b0140","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1007\/s11906-020-1022-z","article-title":"Estrogen and Bisphenol A in Hypertension","volume":"22","author":"Wehbe","year":"2020","journal-title":"Curr. Hypertens. Rep."},{"issue":"9","key":"10.1016\/j.envint.2022.107603_b0145","doi-asserted-by":"crossref","first-page":"750","DOI":"10.1089\/ars.2020.8112","article-title":"Oxidative Stress, GTPCH1, and Endothelial Nitric Oxide Synthase Uncoupling in Hypertension","volume":"34","author":"Wu","year":"2021","journal-title":"Antioxid. Redox Signal."},{"issue":"7","key":"10.1016\/j.envint.2022.107603_b0150","doi-asserted-by":"crossref","first-page":"702","DOI":"10.1161\/CIRCULATIONAHA.113.002271","article-title":"Mitochondrial DNA damage can promote atherosclerosis independently of reactive oxygen species through effects on smooth muscle cells and monocytes and correlates with higher-risk plaques in humans","volume":"128","author":"Yu","year":"2013","journal-title":"Circulation"},{"issue":"9","key":"10.1016\/j.envint.2022.107603_b0155","doi-asserted-by":"crossref","first-page":"180","DOI":"10.46234\/ccdcw2022.044","article-title":"Exposure to Bisphenolic Analogues in the Sixth Total Diet Study - China, 2016\u20132019","volume":"4","author":"Zhang","year":"2022","journal-title":"China CDC Wkly."}],"container-title":["Environment International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S016041202200530X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S016041202200530X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,27]],"date-time":"2025-09-27T12:31:34Z","timestamp":1758976294000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S016041202200530X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,12]]},"references-count":32,"alternative-id":["S016041202200530X"],"URL":"https:\/\/doi.org\/10.1016\/j.envint.2022.107603","relation":{"has-preprint":[{"id-type":"doi","id":"10.1101\/2022.08.15.504011","asserted-by":"object"}]},"ISSN":["0160-4120"],"issn-type":[{"value":"0160-4120","type":"print"}],"subject":[],"published":{"date-parts":[[2022,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Exploring oxidative stress and endothelial dysfunction as a mechanism linking bisphenol S exposure to vascular disease in human umbilical vein endothelial cells and a mouse model of postnatal exposure","name":"articletitle","label":"Article Title"},{"value":"Environment International","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.envint.2022.107603","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 The Authors. Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}],"article-number":"107603"}}