{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T06:05:18Z","timestamp":1787897118502,"version":"build-2784847793"},"reference-count":94,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,7,29]],"date-time":"2024-07-29T00:00:00Z","timestamp":1722211200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82173485"],"award-info":[{"award-number":["82173485"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100006606","name":"Natural Science Foundation of Tianjin Municipality","doi-asserted-by":"publisher","award":["20JCZDJC00320"],"award-info":[{"award-number":["20JCZDJC00320"]}],"id":[{"id":"10.13039\/501100006606","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Environment International"],"published-print":{"date-parts":[[2024,8]]},"DOI":"10.1016\/j.envint.2024.108921","type":"journal-article","created":{"date-parts":[[2024,7,30]],"date-time":"2024-07-30T03:07:55Z","timestamp":1722308875000},"page":"108921","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":12,"special_numbering":"C","title":["Bisphenol mixtures, metal mixtures and type 2 diabetes mellitus: Insights from metabolite profiling"],"prefix":"10.1016","volume":"190","author":[{"given":"Ze","family":"Yang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongbo","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiemin","family":"Wei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruifang","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jingyun","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meiqing","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Changkun","family":"Shen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jian","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kun","family":"Men","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xueli","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pei","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liming","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nai-jun","family":"Tang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.envint.2024.108921_b0005","doi-asserted-by":"crossref","first-page":"1803","DOI":"10.1016\/S0140-6736(22)01655-5","article-title":"Type 2 diabetes","volume":"400","author":"Ahmad","year":"2022","journal-title":"Lancet"},{"key":"10.1016\/j.envint.2024.108921_b0010","doi-asserted-by":"crossref","DOI":"10.3389\/fphar.2021.695418","article-title":"Plasma amino acids metabolomics\u2019 important in glucose management in type 2 diabetes","volume":"12","author":"Alqudah","year":"2021","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.envint.2024.108921_b0015","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1038\/nrc.2016.71","article-title":"From Krebs to clinic: Glutamine metabolism to cancer therapy","volume":"16","author":"Altman","year":"2016","journal-title":"Nat. Rev. Cancer"},{"key":"10.1016\/j.envint.2024.108921_b0020","doi-asserted-by":"crossref","first-page":"2496","DOI":"10.3390\/pharmaceutics14112496","article-title":"Determination of metabolomics profiling in BPA-induced impaired metabolism","volume":"14","author":"Alvi","year":"2022","journal-title":"Pharmaceutics"},{"key":"10.1016\/j.envint.2024.108921_b0025","doi-asserted-by":"crossref","first-page":"15675","DOI":"10.3390\/ijms242115675","article-title":"Vanadium compounds with antidiabetic potential","volume":"24","author":"Amaral","year":"2023","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.envint.2024.108921_b0030","doi-asserted-by":"crossref","unstructured":"American Diabetes Association Professional Practice Committee, 2022. Classification and Diagnosis of Diabetes: Standards of Medical Care in Diabetes-2022. Diabetes Care 45, S17\u2013S38.","DOI":"10.2337\/dc22-S002"},{"key":"10.1016\/j.envint.2024.108921_b0035","doi-asserted-by":"crossref","first-page":"1986","DOI":"10.1056\/NEJM199912233412607","article-title":"Disorders of iron metabolism","volume":"341","author":"Andrews","year":"1999","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.envint.2024.108921_b0040","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1146\/annurev-nutr-071715-050939","article-title":"Iron regulation of pancreatic beta-cell functions and oxidative stress","volume":"36","author":"Backe","year":"2016","journal-title":"Annu. Rev. Nutr."},{"key":"10.1016\/j.envint.2024.108921_b0045","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1186\/1741-7015-10-119","article-title":"Dietary iron intake, body iron stores, and the risk of type 2 diabetes: A systematic review and meta-analysis","volume":"10","author":"Bao","year":"2012","journal-title":"BMC Med."},{"key":"10.1016\/j.envint.2024.108921_b0050","doi-asserted-by":"crossref","DOI":"10.1016\/j.chemosphere.2020.129224","article-title":"U-shaped association between plasma cobalt levels and type 2 diabetes","volume":"267","author":"Cao","year":"2021","journal-title":"Chemosphere"},{"key":"10.1016\/j.envint.2024.108921_b0055","doi-asserted-by":"crossref","first-page":"2151","DOI":"10.1016\/j.clnu.2019.08.033","article-title":"Association between plasma strontium, a bone-seeking element, and type 2 diabetes mellitus","volume":"39","author":"Chen","year":"2020","journal-title":"Clin. Nutr."},{"key":"10.1016\/j.envint.2024.108921_b0060","doi-asserted-by":"crossref","first-page":"5438","DOI":"10.1021\/acs.est.5b05387","article-title":"Bisphenol analogues other than BPA: Environmental occurrence, human exposure, and toxicity-A review","volume":"50","author":"Chen","year":"2016","journal-title":"Environ. Sci. Tech."},{"key":"10.1016\/j.envint.2024.108921_b0065","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2022.107132","article-title":"Associations between urinary bisphenol A and its analogues and semen quality: A cross-sectional study among Chinese men from an infertility clinic","volume":"161","author":"Chen","year":"2022","journal-title":"Environ. Int."},{"key":"10.1016\/j.envint.2024.108921_b0070","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1186\/s12916-021-01991-w","article-title":"Gestational diabetes mellitus is associated with the neonatal gut microbiota and metabolome","volume":"19","author":"Chen","year":"2021","journal-title":"BMC Med."},{"key":"10.1016\/j.envint.2024.108921_b0075","doi-asserted-by":"crossref","first-page":"506","DOI":"10.1124\/pharmrev.121.000408","article-title":"Acylcarnitines: Nomenclature, biomarkers, therapeutic potential, drug targets, and clinical trials","volume":"74","author":"Dambrova","year":"2022","journal-title":"Pharmacol. Rev."},{"key":"10.1016\/j.envint.2024.108921_b0080","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1210\/er.2009-0002","article-title":"Endocrine-disrupting chemicals: An Endocrine Society scientific statement","volume":"30","author":"Diamanti-Kandarakis","year":"2009","journal-title":"Endocr. Rev."},{"key":"10.1016\/j.envint.2024.108921_b0085","doi-asserted-by":"crossref","DOI":"10.3389\/fphar.2021.705498","article-title":"An integrated strategy for rapid discovery and identification of quality markers in Gardenia Fructus using an omics discrimination-grey correlation-biological verification method","volume":"12","author":"Dong","year":"2021","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.envint.2024.108921_b0090","doi-asserted-by":"crossref","first-page":"1719","DOI":"10.1016\/j.envpol.2018.09.093","article-title":"Association of urinary concentrations of bisphenols with type 2 diabetes mellitus: A case-control study","volume":"243","author":"Duan","year":"2018","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.envint.2024.108921_b0095","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2021.106609","article-title":"Perturbation of serum metabolome in relation to type 2 diabetes mellitus and urinary levels of phthalate metabolites and bisphenols","volume":"155","author":"Duan","year":"2021","journal-title":"Environ. Int."},{"key":"10.1016\/j.envint.2024.108921_b0100","doi-asserted-by":"crossref","first-page":"1864","DOI":"10.3390\/nu12061864","article-title":"Role of minerals and trace elements in diabetes and insulin resistance","volume":"12","author":"Dubey","year":"2020","journal-title":"Nutrients"},{"key":"10.1016\/j.envint.2024.108921_b0105","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1016\/j.envint.2019.02.058","article-title":"Pathways of arsenic uptake and efflux","volume":"126","author":"Garbinski","year":"2019","journal-title":"Environ. Int."},{"key":"10.1016\/j.envint.2024.108921_b0110","doi-asserted-by":"crossref","first-page":"E1","DOI":"10.1210\/er.2015-1010","article-title":"The Endocrine Society\u2019s second scientific statement on endocrine-disrupting chemicals","volume":"36","author":"Gore","year":"2015","journal-title":"Endocr. Rev."},{"key":"10.1016\/j.envint.2024.108921_b0115","doi-asserted-by":"crossref","first-page":"833","DOI":"10.2337\/dc15-2251","article-title":"Metabolomics in prediabetes and diabetes: A systematic review and meta-analysis","volume":"39","author":"Guasch-Ferr\u00e9","year":"2016","journal-title":"Diabetes Care"},{"key":"10.1016\/j.envint.2024.108921_b0120","doi-asserted-by":"crossref","first-page":"1508","DOI":"10.1210\/jc.2018-01000","article-title":"Plasma acylcarnitines and risk of type 2 diabetes in a mediterranean population at high cardiovascular risk","volume":"104","author":"Guasch-Ferr\u00e9","year":"2019","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.envint.2024.108921_b0125","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1016\/j.jtemb.2016.12.008","article-title":"Trace elements in early phase type 2 diabetes mellitus-A population-based study. The HUNT study in Norway","volume":"40","author":"Hansen","year":"2017","journal-title":"J. Trace Elem. Med. Biol."},{"key":"10.1016\/j.envint.2024.108921_b0130","doi-asserted-by":"crossref","first-page":"1273","DOI":"10.1289\/ehp.1307082","article-title":"Insulin resistance and environmental pollutants: Experimental evidence and future perspectives","volume":"121","author":"Hectors","year":"2013","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.envint.2024.108921_b0135","doi-asserted-by":"crossref","DOI":"10.1016\/j.jnutbio.2020.108484","article-title":"Cytochrome P450-derived linoleic acid metabolites EpOMEs and DiHOMEs: A review of recent studies","volume":"86","author":"Hildreth","year":"2020","journal-title":"J. Nutr. Biochem."},{"key":"10.1016\/j.envint.2024.108921_b0140","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2023.164307","article-title":"Bisphenol A induced hepatic steatosis by disturbing bile acid metabolism and FXR\/TGR5 signaling pathways via remodeling the gut microbiota in CD-1 mice","volume":"889","author":"Hong","year":"2023","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.envint.2024.108921_b0145","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1053\/j.ajkd.2010.02.344","article-title":"Modification of the CKD epidemiology collaboration (CKD-EPI) equation for Japanese: accuracy and use for population estimates","volume":"56","author":"Horio","year":"2010","journal-title":"Am. J. Kidney Dis."},{"key":"10.1016\/j.envint.2024.108921_b0150","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1210\/endrev\/bnaa026","article-title":"Amino acid sensing in metabolic homeostasis and health","volume":"42","author":"Hu","year":"2021","journal-title":"Endocr. Rev."},{"key":"10.1016\/j.envint.2024.108921_b0155","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/j.mam.2011.10.008","article-title":"The mitochondrial carnitine\/acylcarnitine carrier: Function, structure and physiopathology","volume":"32","author":"Indiveri","year":"2011","journal-title":"Mol. Aspects Med."},{"key":"10.1016\/j.envint.2024.108921_b0160","doi-asserted-by":"crossref","DOI":"10.1016\/j.marenvres.2023.106032","article-title":"Assessment of single and combined effects of bisphenol-A and its analogue bisphenol-S on biochemical and histopathological responses of sea cucumber Holothuria poli","volume":"188","author":"Jenzri","year":"2023","journal-title":"Mar. Environ. Res."},{"key":"10.1016\/j.envint.2024.108921_b0165","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1038\/nrm.2016.25","article-title":"Metabolomics: beyond biomarkers and towards mechanisms","volume":"17","author":"Johnson","year":"2016","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"10.1016\/j.envint.2024.108921_b0170","doi-asserted-by":"crossref","DOI":"10.1016\/j.cbi.2022.110173","article-title":"Essential metals in health and disease","volume":"367","author":"Jomova","year":"2022","journal-title":"Chem. Biol. Interact."},{"key":"10.1016\/j.envint.2024.108921_b0175","doi-asserted-by":"crossref","first-page":"1043970","DOI":"10.3389\/fphar.2022.1043970","article-title":"Inosine: A bioactive metabolite with multimodal actions in human diseases","volume":"13","author":"Kim","year":"2022","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.envint.2024.108921_b0180","doi-asserted-by":"crossref","first-page":"1303","DOI":"10.1001\/jama.300.11.1303","article-title":"Association of urinary bisphenol A concentration with medical disorders and laboratory abnormalities in adults","volume":"300","author":"Lang","year":"2008","journal-title":"J. Am. Med. Assoc."},{"key":"10.1016\/j.envint.2024.108921_b0185","doi-asserted-by":"crossref","first-page":"987","DOI":"10.1016\/j.envint.2009.03.008","article-title":"Influence of environment on insulin sensitivity","volume":"35","author":"Latini","year":"2009","journal-title":"Environ. Int."},{"key":"10.1016\/j.envint.2024.108921_b0190","doi-asserted-by":"crossref","first-page":"1029","DOI":"10.1210\/en.2012-1445","article-title":"Manganese supplementation protects against diet-induced diabetes in wild type mice by enhancing insulin secretion","volume":"154","author":"Lee","year":"2013","journal-title":"Endocrinology"},{"key":"10.1016\/j.envint.2024.108921_b0195","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2020.106227","article-title":"Associations of urinary concentrations of phthalate metabolites, bisphenol A, and parabens with obesity and diabetes mellitus in a Korean adult population: Korean National Environmental Health Survey (KoNEHS) 2015\u20132017","volume":"146","author":"Lee","year":"2021","journal-title":"Environ. Int."},{"key":"10.1016\/j.envint.2024.108921_b0200","doi-asserted-by":"crossref","first-page":"993","DOI":"10.1016\/j.cell.2005.11.026","article-title":"The many faces of PPAR\u03b3","volume":"123","author":"Lehrke","year":"2005","journal-title":"Cell"},{"key":"10.1016\/j.envint.2024.108921_b0205","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/j.bbi.2013.01.005","article-title":"Glucuronic acid and the ethanol metabolite ethyl-glucuronide cause toll-like receptor 4 activation and enhanced pain","volume":"30","author":"Lewis","year":"2013","journal-title":"Brain Behav. Immun."},{"key":"10.1016\/j.envint.2024.108921_b0210","doi-asserted-by":"crossref","first-page":"1903","DOI":"10.1016\/j.chemosphere.2007.07.059","article-title":"Effects of landfill leachate effluent and bisphenol A on glutathione and glutathione-related enzymes in the gills and digestive glands of the freshwater snail Bellamya purificata","volume":"70","author":"Li","year":"2008","journal-title":"Chemosphere"},{"key":"10.1016\/j.envint.2024.108921_b0215","doi-asserted-by":"crossref","first-page":"454","DOI":"10.1016\/j.envint.2019.02.048","article-title":"Heavy metal exposure causes changes in the metabolic health-associated gut microbiome and metabolites","volume":"126","author":"Li","year":"2019","journal-title":"Environ. Int."},{"key":"10.1016\/j.envint.2024.108921_b0220","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2019.113325","article-title":"Association between exposure to arsenic, nickel, cadmium, selenium, and zinc and fasting blood glucose levels","volume":"255","author":"Li","year":"2019","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.envint.2024.108921_b0225","first-page":"482","article-title":"Association between plasma metal levels and diabetes risk: A case-control study in China","volume":"30","author":"Li","year":"2017","journal-title":"Biomed. Environ. Sci."},{"key":"10.1016\/j.envint.2024.108921_b0230","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1742-4658.2006.05607.x","article-title":"Vitamin C. Biosynthesis, recycling and degradation in mammals","volume":"274","author":"Linster","year":"2007","journal-title":"FEBS J."},{"key":"10.1016\/j.envint.2024.108921_b0235","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.envpol.2015.11.046","article-title":"Association of urinary metals levels with type 2 diabetes risk in coke oven workers","volume":"210","author":"Liu","year":"2016","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.envint.2024.108921_b0240","doi-asserted-by":"crossref","DOI":"10.1289\/EHP6641","article-title":"Metabolomic and transcriptomic analysis of MCF-7 cells exposed to 23 chemicals at human-relevant levels: Estimation of individual chemical contribution to effects","volume":"128","author":"Liu","year":"2020","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.envint.2024.108921_b0245","doi-asserted-by":"crossref","first-page":"8042","DOI":"10.3390\/ijms23148042","article-title":"Exposure to bisphenol A caused hepatoxicity and intestinal flora disorder in rats","volume":"23","author":"Liu","year":"2022","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.envint.2024.108921_b0250","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1016\/j.jgg.2015.04.001","article-title":"Orotic acid, more than just an intermediate of pyrimidine de novo synthesis","volume":"42","author":"L\u00f6ffler","year":"2015","journal-title":"J. Genet. Genomics"},{"key":"10.1016\/j.envint.2024.108921_b0255","doi-asserted-by":"crossref","DOI":"10.1016\/j.chemosphere.2020.128021","article-title":"Co-exposure of serum calcium, selenium and vanadium is nonlinearly associated with increased risk of type 2 diabetes mellitus in a Chinese population","volume":"263","author":"Lv","year":"2021","journal-title":"Chemosphere"},{"key":"10.1016\/j.envint.2024.108921_b0260","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1038\/nrendo.2015.129","article-title":"Acylcarnitines\u2014old actors auditioning for new roles in metabolic physiology","volume":"11","author":"McCoin","year":"2015","journal-title":"Nat. Rev. Endocrinol."},{"key":"10.1016\/j.envint.2024.108921_b0265","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2023.108253","article-title":"Emerging roles of epigenetics in lead-induced neurotoxicity","volume":"181","author":"Mei","year":"2023","journal-title":"Environ. Int."},{"key":"10.1016\/j.envint.2024.108921_b0270","doi-asserted-by":"crossref","first-page":"164","DOI":"10.2337\/db15-0316","article-title":"Metals in urine and diabetes in U.S. adults","volume":"65","author":"Menke","year":"2016","journal-title":"Diabetes"},{"key":"10.1016\/j.envint.2024.108921_b0275","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2020.105811","article-title":"Bisphenol A and its analogues: A comprehensive review to identify and prioritize effect biomarkers for human biomonitoring","volume":"144","author":"Mustieles","year":"2020","journal-title":"Environ. Int."},{"key":"10.1016\/j.envint.2024.108921_b0280","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2020.106078","article-title":"A comprehensive review of the neurobehavioral effects of bisphenol S and the mechanisms of action: New insights from in vitro and in vivo models","volume":"145","author":"Naderi","year":"2020","journal-title":"Environ. Int."},{"key":"10.1016\/j.envint.2024.108921_b0285","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2020.143466","article-title":"Effects on the liver lipidome of rat offspring prenatally exposed to bisphenol A","volume":"759","author":"Nguyen","year":"2021","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.envint.2024.108921_b0290","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2021.118452","article-title":"Associations of plasma metal levels with type 2 diabetes and the mediating effects of microRNAs","volume":"292","author":"Nie","year":"2022","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.envint.2024.108921_b0295","doi-asserted-by":"crossref","first-page":"368","DOI":"10.7326\/0003-4819-155-6-201109200-00005","article-title":"Relationship of urinary bisphenol A concentration to risk for prevalent type 2 diabetes in Chinese adults: A cross-sectional analysis","volume":"155","author":"Ning","year":"2011","journal-title":"Ann. Intern. Med."},{"key":"10.1016\/j.envint.2024.108921_b0300","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/j.tem.2015.12.004","article-title":"Exciting times for pancreatic islets: Glutamate signaling in endocrine cells","volume":"27","author":"Otter","year":"2016","journal-title":"Trends Endocrinol. Metab., Special Focus: Endocrine Pancreas"},{"key":"10.1016\/j.envint.2024.108921_b0305","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/j.aquatox.2018.03.024","article-title":"Effects of bisphenol A and its analogs bisphenol F and S on life parameters, antioxidant system, and response of defensome in the marine rotifer Brachionus koreanus","volume":"199","author":"Park","year":"2018","journal-title":"Aquat. Toxicol."},{"key":"10.1016\/j.envint.2024.108921_b0310","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1038\/nrm3314","article-title":"Innovation: Metabolomics: the apogee of the omics trilogy","volume":"13","author":"Patti","year":"2012","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"10.1016\/j.envint.2024.108921_b0315","doi-asserted-by":"crossref","first-page":"2133","DOI":"10.1152\/physrev.00063.2017","article-title":"Mechanisms of insulin action and insulin resistance","volume":"98","author":"Petersen","year":"2018","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.envint.2024.108921_b0320","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1016\/j.tcb.2023.04.007","article-title":"Inosine: novel activator of brown adipose tissue and energy homeostasis","volume":"34","author":"Pfeifer","year":"2023","journal-title":"Trends Cell Biol."},{"key":"10.1016\/j.envint.2024.108921_b0325","doi-asserted-by":"crossref","unstructured":"Ranci\u00e8re, F., Botton, J., Slama, R., Lacroix, M.Z., Debrauwer, L., Charles, M.A., Roussel, R., Balkau, B., Magliano, D.J., D.E.S.I.R. Study Group, 2019. Exposure to Bisphenol A and Bisphenol S and Incident Type 2 Diabetes: A Case-Cohort Study in the French Cohort D.E.S.I.R. Environ Health Perspect 127, 107013.","DOI":"10.1289\/EHP5159"},{"key":"10.1016\/j.envint.2024.108921_b0330","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1289\/ehp.1408989","article-title":"Bisphenol S and F: A systematic review and comparison of the hormonal activity of bisphenol A substitutes","volume":"123","author":"Rochester","year":"2015","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.envint.2024.108921_b0335","doi-asserted-by":"crossref","DOI":"10.1016\/j.biopha.2019.108802","article-title":"Role of cadmium and arsenic as endocrine disruptors in the metabolism of carbohydrates: Inserting the association into perspectives","volume":"114","author":"Sabir","year":"2019","journal-title":"Biomed. Pharmacother."},{"key":"10.1016\/j.envint.2024.108921_b0340","doi-asserted-by":"crossref","first-page":"333","DOI":"10.3322\/caac.21670","article-title":"Metabolomics in cancer research and emerging applications in clinical oncology","volume":"71","author":"Schmidt","year":"2021","journal-title":"CA Cancer J. Clin."},{"key":"10.1016\/j.envint.2024.108921_b0345","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/j.jtemb.2017.03.001","article-title":"Trace element status in patients with type 2 diabetes in Norway: The HUNT3 Survey","volume":"41","author":"Simi\u0107","year":"2017","journal-title":"J. Trace Elem. Med Biol."},{"key":"10.1016\/j.envint.2024.108921_b0350","doi-asserted-by":"crossref","first-page":"764","DOI":"10.1056\/NEJM197304122881505","article-title":"Pyrimidine metabolism in man","volume":"288","author":"Smith","year":"1973","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.envint.2024.108921_b0355","doi-asserted-by":"crossref","DOI":"10.1016\/j.redox.2022.102236","article-title":"The role of selenium in type-2 diabetes mellitus and its metabolic comorbidities","volume":"50","author":"Steinbrenner","year":"2022","journal-title":"Redox Biol."},{"key":"10.1016\/j.envint.2024.108921_b0360","doi-asserted-by":"crossref","first-page":"616","DOI":"10.1289\/ehp.1307201","article-title":"Association of urinary concentrations of bisphenol A and phthalate metabolites with risk of type 2 diabetes: A prospective investigation in the Nurses\u2019 Health Study (NHS) and NHSII cohorts","volume":"122","author":"Sun","year":"2014","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.envint.2024.108921_b0365","doi-asserted-by":"crossref","first-page":"1563","DOI":"10.2337\/dc16-0232","article-title":"Early prediction of developing type 2 diabetes by plasma acylcarnitines: A population-based study","volume":"39","author":"Sun","year":"2016","journal-title":"Diabetes Care"},{"key":"10.1016\/j.envint.2024.108921_b0370","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2021.127097","article-title":"The hazardous threat of Bisphenol A: Toxicity, detection and remediation","volume":"423","author":"Tarafdar","year":"2022","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.envint.2024.108921_b0375","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/j.cbi.2018.10.028","article-title":"Pro- and antioxidant activity of chromium (III), iron (III), molybdenum (III) or nickel (II) and their mixtures","volume":"298","author":"Terpilowska","year":"2019","journal-title":"Chem. Biol. Interact."},{"key":"10.1016\/j.envint.2024.108921_b0380","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1021\/ar990073r","article-title":"Elucidating a biological role for chromium at a molecular level","volume":"33","author":"Vincent","year":"2000","journal-title":"Acc. Chem. Res."},{"key":"10.1016\/j.envint.2024.108921_b0385","doi-asserted-by":"crossref","first-page":"4205","DOI":"10.1007\/s12011-022-03502-1","article-title":"Association of CYP19A1 gene, plasma zinc, and urinary zinc with the risk of type 2 diabetes mellitus in a Chinese population","volume":"201","author":"Wang","year":"2023","journal-title":"Biol. Trace Elem. Res."},{"key":"10.1016\/j.envint.2024.108921_b0390","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2022.119581","article-title":"Combined effects of bisphenol A and diabetes genetic risk score on incident type 2 diabetes: A nested case-control study","volume":"307","author":"Wang","year":"2022","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.envint.2024.108921_b0395","doi-asserted-by":"crossref","first-page":"552","DOI":"10.1016\/j.cellsig.2016.02.010","article-title":"The adenosine metabolite inosine is a functional agonist of the adenosine A2A receptor with a unique signaling bias","volume":"28","author":"Welihinda","year":"2016","journal-title":"Cell. Signal."},{"key":"10.1016\/j.envint.2024.108921_b0400","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1093\/jn\/134.3.489","article-title":"Glutathione metabolism and its implications for health","volume":"134","author":"Wu","year":"2004","journal-title":"J. Nutr."},{"key":"10.1016\/j.envint.2024.108921_b0405","doi-asserted-by":"crossref","DOI":"10.1016\/j.phrs.2023.106647","article-title":"Comparative effects of vitamin and mineral supplements in the management of type 2 diabetes in primary care: A systematic review and network meta-analysis of randomized controlled trials","volume":"188","author":"Xia","year":"2023","journal-title":"Pharmacol. Res."},{"key":"10.1016\/j.envint.2024.108921_b0410","doi-asserted-by":"crossref","first-page":"1327","DOI":"10.1016\/j.scitotenv.2018.01.317","article-title":"Oxidative DNA damage mediates the association between urinary metals and prevalence of type 2 diabetes mellitus in Chinese adults","volume":"627","author":"Xiao","year":"2018","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.envint.2024.108921_b0415","doi-asserted-by":"crossref","DOI":"10.1016\/j.envres.2021.112535","article-title":"Urinary element profiles and associations with cardiometabolic diseases: A cross-sectional study across ten areas in China","volume":"205","author":"Xu","year":"2022","journal-title":"Environ. Res."},{"key":"10.1016\/j.envint.2024.108921_b0420","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2023.168678","article-title":"A nested case-control study of serum zinc and incident diabetes among Chinese adults: Effect modifications and mediation analysis","volume":"910","author":"Yang","year":"2024","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.envint.2024.108921_b0425","doi-asserted-by":"crossref","unstructured":"Yang, J., Chan, K., Choi, C., Yang, A., Lo, K., 2022. Identifying Effects of Urinary Metals on Type 2 Diabetes in U.S. Adults: Cross-Sectional Analysis of National Health and Nutrition Examination Survey 2011-2016. Nutrients 14, 1552.","DOI":"10.3390\/nu14081552"},{"key":"10.1016\/j.envint.2024.108921_b0430","doi-asserted-by":"crossref","first-page":"2435","DOI":"10.1007\/s10653-022-01366-x","article-title":"Exposure to multiple metals and diabetes mellitus risk in dong ethnicity in China: From the China multi-ethnic cohort study","volume":"45","author":"Yang","year":"2023","journal-title":"Environ. Geochem. Health"},{"key":"10.1016\/j.envint.2024.108921_b0435","doi-asserted-by":"crossref","first-page":"8152","DOI":"10.1002\/jcp.27603","article-title":"Insulin resistance: Review of the underlying molecular mechanisms","volume":"234","author":"Yaribeygi","year":"2019","journal-title":"J. Cell. Physiol."},{"key":"10.1016\/j.envint.2024.108921_b0440","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1016\/j.jtemb.2015.11.001","article-title":"Serum zinc and risk of type 2 diabetes incidence in men: The Kuopio Ischaemic Heart Disease Risk Factor Study","volume":"33","author":"Yary","year":"2016","journal-title":"J. Trace Elem. Med Biol."},{"key":"10.1016\/j.envint.2024.108921_b0445","doi-asserted-by":"crossref","first-page":"917","DOI":"10.1016\/j.envpol.2018.01.046","article-title":"Associations of multiple plasma metals with incident type 2 diabetes in Chinese adults: The Dongfeng-Tongji Cohort","volume":"237","author":"Yuan","year":"2018","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.envint.2024.108921_b0450","doi-asserted-by":"crossref","first-page":"57","DOI":"10.3389\/fphar.2018.00057","article-title":"Zinc oxide nanoparticle caused plasma metabolomic perturbations correlate with hepatic steatosis","volume":"9","author":"Zhang","year":"2018","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.envint.2024.108921_b0455","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2021.106893","article-title":"Dose-response metabolomics and pathway sensitivity to map molecular cartography of bisphenol A exposure","volume":"158","author":"Zhao","year":"2022","journal-title":"Environ. Int."},{"key":"10.1016\/j.envint.2024.108921_b0460","doi-asserted-by":"crossref","DOI":"10.1016\/j.redox.2020.101475","article-title":"Redox toxicology of environmental chemicals causing oxidative stress","volume":"34","author":"Zheng","year":"2020","journal-title":"Redox Biol."},{"key":"10.1016\/j.envint.2024.108921_b0465","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2023.166534","article-title":"The effects of heatwave on cognitive impairment among older adults: Exploring the combined effects of air pollution and green space","volume":"904","author":"Zhou","year":"2023","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.envint.2024.108921_b0470","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2021.146074","article-title":"Retention of thallium by natural minerals: A review","volume":"777","author":"Zhuang","year":"2021","journal-title":"Sci. Total Environ."}],"container-title":["Environment International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0160412024005075?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0160412024005075?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,11,14]],"date-time":"2024-11-14T17:57:21Z","timestamp":1731607041000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0160412024005075"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,8]]},"references-count":94,"alternative-id":["S0160412024005075"],"URL":"https:\/\/doi.org\/10.1016\/j.envint.2024.108921","relation":{},"ISSN":["0160-4120"],"issn-type":[{"value":"0160-4120","type":"print"}],"subject":[],"published":{"date-parts":[[2024,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Bisphenol mixtures, metal mixtures and type 2 diabetes mellitus: Insights from metabolite profiling","name":"articletitle","label":"Article Title"},{"value":"Environment International","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.envint.2024.108921","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 The Authors. Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}],"article-number":"108921"}}