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Available at: https:\/\/www.epa.gov\/sdwa\/and-polyfluoroalkyl-substances-pfas."},{"key":"10.1016\/j.envint.2025.109589_b0310","unstructured":"U.S. Government Accountability Office (GAO). 2024. Firefighting Foam: DOD is Working to Address Challenges to Transitioning to PFAS-Free Alternatives. Available at: https:\/\/www.gao.gov\/products\/gao-24-107322."},{"key":"10.1016\/j.envint.2025.109589_b0315","doi-asserted-by":"crossref","unstructured":"Verner, M.A., Ngueta, G., Jensen, E.T., Fromme, H., V\u00f6lkel, W., Nygaard, U.C., Granum, B., Longnecker, M.P., 2016. A Simple pharmacokinetic model of prenatal and postnatal exposure to perfluoroalkyl substances (PFASs). Environ. Sci. Technol. 19, 50(2), 978\u2013986. 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