{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T14:17:41Z","timestamp":1783433861662,"version":"3.54.6"},"reference-count":62,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T00:00:00Z","timestamp":1778544000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["U23A205"],"award-info":[{"award-number":["U23A205"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["22476100"],"award-info":[{"award-number":["22476100"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005236","name":"Chinese Universities Scientific Fund","doi-asserted-by":"publisher","award":["2452021103"],"award-info":[{"award-number":["2452021103"]}],"id":[{"id":"10.13039\/501100005236","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002855","name":"Ministry of Science and Technology of the People's Republic of China","doi-asserted-by":"publisher","award":["2022YFC3703200"],"award-info":[{"award-number":["2022YFC3703200"]}],"id":[{"id":"10.13039\/501100002855","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100013804","name":"Fundamental Research Funds for the Central Universities","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100013804","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004945","name":"Nankai University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004945","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012226","name":"Fundamental Research Funds for the Central Universities","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100012226","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002338","name":"Ministry of Education of the People's Republic of China","doi-asserted-by":"publisher","award":["B17025"],"award-info":[{"award-number":["B17025"]}],"id":[{"id":"10.13039\/501100002338","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Environment International"],"published-print":{"date-parts":[[2026,6]]},"DOI":"10.1016\/j.envint.2026.110308","type":"journal-article","created":{"date-parts":[[2026,5,14]],"date-time":"2026-05-14T03:17:21Z","timestamp":1778728641000},"page":"110308","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Sodium p-perfluorous nonenoxybenzenesulfonate directly targets on mitochondrial proteins to disrupt metabolic cascade and promote nephrotoxicity"],"prefix":"10.1016","volume":"212","author":[{"given":"Yang","family":"Lyu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruyu","family":"Guo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bingxin","family":"Gui","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenjue","family":"Zhong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lingyan","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.envint.2026.110308_b0005","doi-asserted-by":"crossref","first-page":"1365","DOI":"10.1038\/leu.2016.26","article-title":"The TCA cycle transferase DLST is important for MYC-mediated leukemogenesis","volume":"30","author":"Anderson","year":"2016","journal-title":"Leukemia"},{"issue":"6","key":"10.1016\/j.envint.2026.110308_b0010","doi-asserted-by":"crossref","first-page":"1135","DOI":"10.1016\/j.kint.2023.08.006","article-title":"Abnormal lactate metabolism is linked to albuminuria and kidney injury in diabetic nephropathy","volume":"104","author":"Azushima","year":"2023","journal-title":"Kidney Int."},{"issue":"7947","key":"10.1016\/j.envint.2026.110308_b0015","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1038\/s41586-022-05661-6","article-title":"Slow TCA flux and ATP production in primary solid tumours but not metastases","volume":"614","author":"Bartman","year":"2023","journal-title":"Nature"},{"issue":"10","key":"10.1016\/j.envint.2026.110308_b0020","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1038\/nrneph.2017.107","article-title":"Mitochondrial energetics in the kidney","volume":"13","author":"Bhargava","year":"2017","journal-title":"Nat. Rev. Nephrol."},{"issue":"8","key":"10.1016\/j.envint.2026.110308_b0025","doi-asserted-by":"crossref","first-page":"1215","DOI":"10.1093\/jn\/124.8.1215","article-title":"Lysine-\u03b1-ketoglutarate reductase and saccharopine dehydrogenase are located only in the mitochondrial matrix in rat liver","volume":"124","author":"Blemings","year":"1994","journal-title":"J. Nutri."},{"issue":"3","key":"10.1016\/j.envint.2026.110308_b0030","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1016\/j.cmet.2021.02.007","article-title":"The phytochemical hyperforin triggers thermogenesis in adipose tissue via a Dlat-AMPK signaling axis to curb obesity","volume":"33","author":"Chen","year":"2021","journal-title":"Cell Metab."},{"key":"10.1016\/j.envint.2026.110308_b0035","doi-asserted-by":"crossref","first-page":"948","DOI":"10.1016\/j.scitotenv.2019.01.361","article-title":"The toxic potentials and focus of disinfection byproducts based on the human embryonic kidney (HEK293) cell model","volume":"664","author":"Chen","year":"2019","journal-title":"Sci. Total Environ."},{"issue":"23","key":"10.1016\/j.envint.2026.110308_b0040","doi-asserted-by":"crossref","first-page":"11455","DOI":"10.1021\/acs.est.4c12668","article-title":"Medium-chain chlorinated paraffins induced reproductive toxicity in female rats by interfering with oocyte meiosis and triggering DNA damage","volume":"59","author":"Cheng","year":"2025","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.envint.2026.110308_b0045","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1016\/j.semcancer.2017.06.008","article-title":"The TCA cycle as a bridge between oncometabolism and DNA transactions in cancer","volume":"47","author":"Ciccarone","year":"2017","journal-title":"Semi. Cancer Biol."},{"issue":"5","key":"10.1016\/j.envint.2026.110308_b0050","doi-asserted-by":"crossref","first-page":"793","DOI":"10.1016\/j.cmet.2018.07.020","article-title":"Isotope tracing of human clear cell renal cell carcinomas demonstrates suppressed glucose oxidation in vivo","volume":"28","author":"Courtney","year":"2018","journal-title":"Cell Metab."},{"key":"10.1016\/j.envint.2026.110308_b0055","doi-asserted-by":"crossref","DOI":"10.1016\/j.aquatox.2023.106570","article-title":"Cadmium induced time-dependent kidney injury in common carp via mitochondrial pathway: Impaired mitochondrial energy metabolism and mitochondrion-dependent apoptosis","volume":"261","author":"Cui","year":"2023","journal-title":"Aquatic Toxicol."},{"issue":"4","key":"10.1016\/j.envint.2026.110308_b0060","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1016\/j.ymgme.2021.10.003","article-title":"A knock-in rat model unravels acute and chronic renal toxicity in glutaric aciduria type I","volume":"134","author":"Gonzalez Melo","year":"2021","journal-title":"Mol. Genet. Metab."},{"issue":"13","key":"10.1016\/j.envint.2026.110308_b0065","doi-asserted-by":"crossref","first-page":"2631","DOI":"10.1523\/JNEUROSCI.1459-21.2022","article-title":"The metabolite saccharopine impairs neuronal development by inhibiting the neurotrophic function of glucose-6-phosphate isomerase","volume":"42","author":"Guo","year":"2022","journal-title":"J. Neurosci."},{"key":"10.1016\/j.envint.2026.110308_b0070","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1016\/j.ebiom.2017.10.027","article-title":"Metabolomics and gene expression analysis reveal down-regulation of the citric acid (TCA) cycle in non-diabetic CKD patients","volume":"26","author":"Hallan","year":"2017","journal-title":"EBioMedicine"},{"issue":"37","key":"10.1016\/j.envint.2026.110308_b0075","doi-asserted-by":"crossref","first-page":"16258","DOI":"10.1021\/acs.est.4c03053","article-title":"Perfluorohexanesulfonic acid (PFHxS) impairs lipid homeostasis in zebrafish larvae through activation of PPAR\u03b1","volume":"58","author":"He","year":"2024","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.envint.2026.110308_b0080","doi-asserted-by":"crossref","DOI":"10.1016\/j.metabol.2023.155614","article-title":"Roles of malate and aspartate in gluconeogenesis in various physiological and pathological states","volume":"145","author":"Hole\u010dek","year":"2023","journal-title":"Metabolism"},{"issue":"12","key":"10.1016\/j.envint.2026.110308_b0085","doi-asserted-by":"crossref","first-page":"8103","DOI":"10.1021\/acs.est.2c01287","article-title":"Emissions, isomer-specific environmental behavior, and transformation of OBS from one major fluorochemical manufacturing facility in China","volume":"56","author":"Hou","year":"2022","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.envint.2026.110308_b0090","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2021.127950","article-title":"Comparative chronic toxicities of PFOS and its novel alternatives on the immune system associated with intestinal microbiota dysbiosis in adult zebrafish","volume":"425","author":"Huang","year":"2022","journal-title":"J. Hazard. Mater."},{"issue":"6","key":"10.1016\/j.envint.2026.110308_b0095","doi-asserted-by":"crossref","first-page":"770","DOI":"10.1159\/000515012","article-title":"Rhabdomyolysis, acute kidney injury, and a novel frameshift mutation in a child with glutaric acidemia type I","volume":"145","author":"Huang","year":"2021","journal-title":"Nephron"},{"issue":"12","key":"10.1016\/j.envint.2026.110308_b0100","doi-asserted-by":"crossref","first-page":"771","DOI":"10.1038\/s41581-024-00872-8","article-title":"Amino acid metabolism in kidney health and disease","volume":"20","author":"Knol","year":"2024","journal-title":"Nat. Rev. Nephrol."},{"issue":"1","key":"10.1016\/j.envint.2026.110308_b0105","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/j.ymgme.2020.07.010","article-title":"The lysine degradation pathway: subcellular compartmentalization and enzyme deficiencies","volume":"131","author":"Leandro","year":"2020","journal-title":"Mol. Genet. Metab."},{"issue":"1","key":"10.1016\/j.envint.2026.110308_b0110","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1038\/s41392-022-01151-3","article-title":"Lactate metabolism in human health and disease","volume":"7","author":"Li","year":"2022","journal-title":"Signal Transduct. Target. Ther."},{"key":"10.1016\/j.envint.2026.110308_b0115","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2024.136509","article-title":"Occurrence of per- and polyfluoroalkyl substances in wheat, maize, rice, and soybean from chinese major grain producing regions","volume":"480","author":"Li","year":"2024","journal-title":"J. Hazard. Mater."},{"issue":"22","key":"10.1016\/j.envint.2026.110308_b0120","doi-asserted-by":"crossref","first-page":"10799","DOI":"10.1021\/acs.est.4c14697","article-title":"Renal dysfunction induced by sodium p-perfluorous nonenoxybenzenesulfonate in mice: Insights from the intrinsic mechanisms of proteinuria","volume":"59","author":"Lyu","year":"2025","journal-title":"Environ. Sci. Technol."},{"issue":"15","key":"10.1016\/j.envint.2026.110308_b0125","doi-asserted-by":"crossref","first-page":"7461","DOI":"10.1021\/acs.est.4c10724","article-title":"Exposure to sodium p-perfluorous nonenoxybenzenesulfonate induces renal fibrosis in mice by disrupting lysine metabolism","volume":"59","author":"Lyu","year":"2025","journal-title":"Environ. Sci. Technol."},{"issue":"2","key":"10.1016\/j.envint.2026.110308_b0130","doi-asserted-by":"crossref","first-page":"1113","DOI":"10.1021\/acs.est.1c05915","article-title":"In vivo effects of silver nanoparticles on development, behavior, and mitochondrial function are altered by genetic defects in mitochondrial dynamics","volume":"56","author":"Mello","year":"2022","journal-title":"Environ. Sci. Technol."},{"issue":"1","key":"10.1016\/j.envint.2026.110308_b0135","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1038\/s41581-024-00889-z","article-title":"Metabolism at the crossroads of inflammation and fibrosis in chronic kidney disease","volume":"21","author":"Miguel","year":"2025","journal-title":"Nat. Rev. Nephrol."},{"issue":"10","key":"10.1016\/j.envint.2026.110308_b0140","doi-asserted-by":"crossref","first-page":"1747","DOI":"10.1038\/s42255-023-00855-2","article-title":"Glutarate regulates T cell metabolism and anti-tumour immunity","volume":"5","author":"Minogue","year":"2023","journal-title":"Nat. Metab."},{"issue":"6141","key":"10.1016\/j.envint.2026.110308_b0145","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1126\/science.1233606","article-title":"Monitoring drug target engagement in cells and tissues using the cellular thermal shift assay","volume":"341","author":"Molina","year":"2013","journal-title":"Science"},{"issue":"1","key":"10.1016\/j.envint.2026.110308_b0150","doi-asserted-by":"crossref","first-page":"4847","DOI":"10.1038\/s41467-021-24934-8","article-title":"The enzymatic activity of inositol hexakisphosphate kinase controls circulating phosphate in mammals","volume":"12","author":"Moritoh","year":"2021","journal-title":"Nat. Commun."},{"issue":"4","key":"10.1016\/j.envint.2026.110308_b0155","doi-asserted-by":"crossref","first-page":"724","DOI":"10.1016\/j.kint.2023.06.022","article-title":"Inhibition of pyruvate dehydrogenase kinase 4 ameliorates kidney ischemia-reperfusion injury by reducing succinate accumulation during ischemia and preserving mitochondrial function during reperfusion","volume":"104","author":"Oh","year":"2023","journal-title":"Kidney Int."},{"key":"10.1016\/j.envint.2026.110308_b0160","doi-asserted-by":"crossref","DOI":"10.1016\/j.phrs.2024.107261","article-title":"Sirtuin 3 in renal diseases and aging: from mechanisms to potential therapies","volume":"206","author":"Peng","year":"2024","journal-title":"Pharmacol. Res."},{"key":"10.1016\/j.envint.2026.110308_b0165","doi-asserted-by":"crossref","DOI":"10.1016\/j.redox.2023.102932","article-title":"Defective function of \u03b1-ketoglutarate dehydrogenase exacerbates mitochondrial ATP deficits during complex I deficiency","volume":"67","author":"Piroli","year":"2023","journal-title":"Redox Biol."},{"issue":"4","key":"10.1016\/j.envint.2026.110308_b0170","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1016\/j.ajhg.2019.02.017","article-title":"Recurrent germline DLST mutations in individuals with multiple pheochromocytomas and paragangliomas","volume":"104","author":"Remacha","year":"2019","journal-title":"Am. J. Hum. Genet."},{"issue":"17","key":"10.1016\/j.envint.2026.110308_b0175","doi-asserted-by":"crossref","first-page":"6482","DOI":"10.1021\/acs.analchem.1c04627","article-title":"Matrix thermal shift assay for fast construction of multidimensional ligand\u2013target space","volume":"94","author":"Ruan","year":"2022","journal-title":"Anal. Chem."},{"key":"10.1016\/j.envint.2026.110308_b0180","volume":"eLife 10","author":"Ryan","year":"2021","journal-title":"Disruption of the TCA Cycle Reveals an ATF4-Dependent Integration of Redox and Amino Acid Metabolism."},{"issue":"11","key":"10.1016\/j.envint.2026.110308_b0185","doi-asserted-by":"crossref","first-page":"2946","DOI":"10.1016\/j.celrep.2018.08.014","article-title":"Disease-linked glutarylation impairs function and interactions of mitochondrial proteins and contributes to mitochondrial heterogeneity","volume":"24","author":"Schmiesing","year":"2018","journal-title":"Cell Rep."},{"issue":"18","key":"10.1016\/j.envint.2026.110308_b0190","doi-asserted-by":"crossref","first-page":"11092","DOI":"10.1021\/acs.analchem.8b02995","article-title":"Integrative chemical proteomics-metabolomics approach reveals Acaca\/Acacb as direct molecular targets of PFOA","volume":"90","author":"Shao","year":"2018","journal-title":"Anal. Chem."},{"issue":"1","key":"10.1016\/j.envint.2026.110308_b0195","doi-asserted-by":"crossref","first-page":"1289","DOI":"10.1038\/s42003-021-02805-8","article-title":"DLST-dependence dictates metabolic heterogeneity in TCA-cycle usage among triple-negative breast cancer","volume":"4","author":"Shen","year":"2021","journal-title":"Commun. Biol."},{"issue":"4","key":"10.1016\/j.envint.2026.110308_b0200","doi-asserted-by":"crossref","first-page":"526","DOI":"10.1016\/j.sbi.2013.06.013","article-title":"Revealing various coupling of electron transfer and proton pumping in mitochondrial respiratory chain","volume":"23","author":"Sun","year":"2013","journal-title":"Curr. Opin. Struc. Biol."},{"issue":"11","key":"10.1016\/j.envint.2026.110308_b0205","doi-asserted-by":"crossref","first-page":"2601","DOI":"10.1016\/j.cell.2024.04.037","article-title":"Mitochondria at the crossroads of health and disease","volume":"187","author":"Suomalainen","year":"2024","journal-title":"Cell"},{"issue":"1","key":"10.1016\/j.envint.2026.110308_b0210","doi-asserted-by":"crossref","first-page":"9977","DOI":"10.1038\/s41467-024-54222-0","article-title":"ATP dynamics as a predictor of future podocyte structure and function after acute ischemic kidney injury in female mice","volume":"15","author":"Takahashi","year":"2024","journal-title":"Nat. Commun."},{"issue":"2","key":"10.1016\/j.envint.2026.110308_b0215","doi-asserted-by":"crossref","first-page":"1076","DOI":"10.1021\/acs.est.3c08577","article-title":"Isothiazolinone disrupts reproductive endocrinology by targeting the G-protein-coupled receptor signaling","volume":"58","author":"Tang","year":"2024","journal-title":"Environ. Sci. Technol."},{"issue":"10","key":"10.1016\/j.envint.2026.110308_b0220","doi-asserted-by":"crossref","first-page":"1771","DOI":"10.1111\/epi.13862","article-title":"Impairment of GABAergic system contributes to epileptogenesis in glutaric acidemia type I","volume":"58","author":"Vendramin Pasquetti","year":"2017","journal-title":"Epilepsia"},{"key":"10.1016\/j.envint.2026.110308_b0225","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1016\/j.envint.2019.05.056","article-title":"Bioaccumulation in the gut and liver causes gut barrier dysfunction and hepatic metabolism disorder in mice after exposure to low doses of OBS","volume":"129","author":"Wang","year":"2019","journal-title":"Environ. Int."},{"key":"10.1016\/j.envint.2026.110308_b0230","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2024.123632","article-title":"The adverse effects of developmental exposure to polystyrene nanoparticles on cognitive function in weaning rats and the protective role of trihydroxy phenolacetone","volume":"347","author":"Wang","year":"2024","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.envint.2026.110308_b0235","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2023.130959","article-title":"Insights into the circadian rhythm alterations of the novel PFOS substitutes F-53B and OBS on adult zebrafish","volume":"448","author":"Wang","year":"2023","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.envint.2026.110308_b0240","article-title":"Bioaccumulation, tissue distribution, and maternal transfer of novel PFOS alternatives (6:2 Cl-PFESA and OBS) in wild freshwater fish from Poyang Lake","volume":"336","author":"Wang","year":"2023","journal-title":"China. Chemosphere"},{"issue":"42","key":"10.1016\/j.envint.2026.110308_b0245","doi-asserted-by":"crossref","first-page":"18619","DOI":"10.1021\/acs.est.4c07053","article-title":"Benzo(a)anthracene targeting SLC1A5 to synergistically enhance PAH mixture toxicity","volume":"58","author":"Wang","year":"2024","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.envint.2026.110308_b0250","doi-asserted-by":"crossref","DOI":"10.1016\/j.redox.2023.102930","article-title":"Uncovering SOD3 and GPX4 as new targets of Benzo[\u03b1]pyrene-induced hepatotoxicity through Metabolomics and Chemical Proteomics","volume":"67","author":"Wang","year":"2023","journal-title":"Redox Biol."},{"issue":"1","key":"10.1016\/j.envint.2026.110308_b0255","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1111\/cas.16347","article-title":"Noncanonical TCA cycle fosters canonical TCA cycle and mitochondrial integrity in acute myeloid leukemia","volume":"116","author":"Watanabe","year":"2025","journal-title":"Cancer Sci."},{"issue":"24","key":"10.1016\/j.envint.2026.110308_b0260","doi-asserted-by":"crossref","first-page":"14173","DOI":"10.1021\/acs.est.7b04332","article-title":"Discovery of a novel polyfluoroalkyl benzenesulfonic acid around oilfields in northern China","volume":"51","author":"Xu","year":"2017","journal-title":"Environ. Sci. Technol."},{"issue":"3","key":"10.1016\/j.envint.2026.110308_b0265","doi-asserted-by":"crossref","first-page":"1842","DOI":"10.1021\/acs.est.0c05832","article-title":"System biology-guided chemical proteomics to discover protein targets of monoethylhexyl phthalate in regulating cell cycle","volume":"55","author":"Xu","year":"2021","journal-title":"Environ. Sci. Technol."},{"issue":"7","key":"10.1016\/j.envint.2026.110308_b0270","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1007\/s11270-023-06512-4","article-title":"Developmental toxicity and cardiotoxicity induced by PFOS and its novel alternative OBS in early life stage of zebrafish (Danio rerio)","volume":"234","author":"Yang","year":"2023","journal-title":"Water Air Soil Pollut."},{"key":"10.1016\/j.envint.2026.110308_b0275","doi-asserted-by":"crossref","first-page":"8329","DOI":"10.1021\/acs.est.4c10565","article-title":"multiomic landscape of primary hypothyroidism induced by subchronic exposure to low-dose novel PFOS substitute OBS in human and murine models","volume":"59","author":"Yang","year":"2025","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.envint.2026.110308_b0280","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2024.176895","article-title":"Evaluating pulmonary toxicity of PFOS and its alternative OBS using spheroids of A549 cells","volume":"955","author":"Yao","year":"2024","journal-title":"Sci. Total Environ."},{"issue":"51","key":"10.1016\/j.envint.2026.110308_b0285","doi-asserted-by":"crossref","first-page":"22646","DOI":"10.1021\/acs.est.4c10081","article-title":"ChemNTP: Advanced prediction of neurotoxicity targets for environmental chemicals using a siamese neural network","volume":"58","author":"Zhang","year":"2024","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.envint.2026.110308_b0290","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/j.cca.2015.12.003","article-title":"Clinical and molecular investigation in chinese patients with glutaric aciduria type I","volume":"453","author":"Zhang","year":"2016","journal-title":"Clin. Chim. Acta"},{"issue":"03","key":"10.1016\/j.envint.2026.110308_b0295","first-page":"240","article-title":"Role of dihydro lipoamidesuccinyl transferase in mice renal interstitial fibrosis","volume":"27","author":"Zhang","year":"2018","journal-title":"Chin. J. Nephrol. Dial. Transpl."},{"key":"10.1016\/j.envint.2026.110308_b0300","doi-asserted-by":"crossref","DOI":"10.1016\/j.arr.2020.101250","article-title":"Role of mitochondrial quality surveillance in myocardial infarction: from bench to bedside","volume":"66","author":"Zhou","year":"2021","journal-title":"Ageing Res. Rev."},{"key":"10.1016\/j.envint.2026.110308_b0305","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2022.107289","article-title":"Tissue distribution of sodium p-perfluorous nonenoxybenzene sulfonate (OBS) in mice via oral exposure","volume":"165","author":"Zhou","year":"2022","journal-title":"Environ. Int."},{"issue":"12","key":"10.1016\/j.envint.2026.110308_b0310","doi-asserted-by":"crossref","DOI":"10.1289\/EHP11969","article-title":"Exploring route-specific pharmacokinetics of PFAS in mice by coupling in vivo tests and physiologically based toxicokinetic models","volume":"131","author":"Zhu","year":"2023","journal-title":"Environ. Health Persp."}],"container-title":["Environment International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0160412026002667?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0160412026002667?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T13:49:36Z","timestamp":1783432176000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0160412026002667"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6]]},"references-count":62,"alternative-id":["S0160412026002667"],"URL":"https:\/\/doi.org\/10.1016\/j.envint.2026.110308","relation":{},"ISSN":["0160-4120"],"issn-type":[{"value":"0160-4120","type":"print"}],"subject":[],"published":{"date-parts":[[2026,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Sodium p-perfluorous nonenoxybenzenesulfonate directly targets on mitochondrial proteins to disrupt metabolic cascade and promote nephrotoxicity","name":"articletitle","label":"Article Title"},{"value":"Environment International","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.envint.2026.110308","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Authors. Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}],"article-number":"110308"}}