{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T20:47:24Z","timestamp":1785876444418,"version":"3.56.0"},"reference-count":30,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,6,15]],"date-time":"2026-06-15T00:00:00Z","timestamp":1781481600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003478","name":"Government of Japan Ministry of Health Labour and Welfare","doi-asserted-by":"publisher","award":["24KA2001"],"award-info":[{"award-number":["24KA2001"]}],"id":[{"id":"10.13039\/501100003478","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Environment International"],"published-print":{"date-parts":[[2026,8]]},"DOI":"10.1016\/j.envint.2026.110374","type":"journal-article","created":{"date-parts":[[2026,6,25]],"date-time":"2026-06-25T15:13:55Z","timestamp":1782400435000},"page":"110374","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Relationship between ovarian reserve and parental exposure in first-generation offspring of Yusho patients"],"prefix":"10.1016","volume":"214","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0906-8277","authenticated-orcid":false,"given":"Norio","family":"Hamada","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seiichi","family":"Morokuma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gaku","family":"Tsuji","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takeshi","family":"Nakahara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kiyoko","family":"Kato","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.envint.2026.110374_b0005","doi-asserted-by":"crossref","DOI":"10.3389\/ftox.2024.1392257","article-title":"Impact of dioxins on reproductive health in female mammals","volume":"6","author":"Aldeli","year":"2024","journal-title":"Front. Toxicol."},{"key":"10.1016\/j.envint.2026.110374_b0010","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1093\/molehr\/gat059","article-title":"Activation of the aryl hydrocarbon receptor by a component of cigarette smoke reduces germ cell proliferation in the human fetal ovary","volume":"20","author":"Anderson","year":"2014","journal-title":"Mol. Hum. Reprod."},{"key":"10.1016\/j.envint.2026.110374_b0015","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1098\/rspb.1963.0055","article-title":"A quantitative and cytological study of germ cells in human ovaries","volume":"158","author":"Baker","year":"1963","journal-title":"Proc. R. Soc. Lond. B"},{"key":"10.1016\/j.envint.2026.110374_b0020","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1093\/toxsci\/56.2.382","article-title":"Physiological role of the aryl hydrocarbon receptor in mouse ovary development","volume":"56","author":"Benedict","year":"2000","journal-title":"Toxicol. Sci."},{"key":"10.1016\/j.envint.2026.110374_b0025","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/j.fertnstert.2013.09.015","article-title":"Race\/ethnic disparities in reproductive age: an examination of ovarian reserve estimates across four race\/ethnic groups of healthy, regularly cycling women","volume":"101","author":"Bleil","year":"2014","journal-title":"Fertil. Steril."},{"key":"10.1016\/j.envint.2026.110374_b0030","doi-asserted-by":"crossref","first-page":"688","DOI":"10.1093\/humupd\/dmu020","article-title":"Anti-M\u00fcllerian hormone: ovarian reserve testing and its potential clinical implications","volume":"20","author":"Broer","year":"2014","journal-title":"Human Reprod Update."},{"key":"10.1016\/j.envint.2026.110374_b0035","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1016\/j.reprotox.2010.10.003","article-title":"Developmental exposure to TCDD reduces fertility and negatively affects pregnancy outcomes across multiple generations","volume":"31","author":"Bruner-Tran","year":"2011","journal-title":"Reprod. Toxicol."},{"key":"10.1016\/j.envint.2026.110374_b0040","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1007\/PL00002973","article-title":"The ah receptor: a regulator of the biochemical and toxicological actions of structurally diverse chemicals","volume":"61","author":"Denison","year":"1998","journal-title":"Bull. Environ. Contam. Toxicol."},{"key":"10.1016\/j.envint.2026.110374_b0045","doi-asserted-by":"crossref","first-page":"858","DOI":"10.1289\/ehp.7820","article-title":"Serum dioxin concentrations and age at menopause","volume":"113","author":"Eskenazi","year":"2005","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.envint.2026.110374_b0050","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1007\/s00420-003-0487-9","article-title":"Yucheng: health effects of prenatal exposure to polychlorinated biphenyls and dibenzofurans","volume":"77","author":"Guo","year":"2004","journal-title":"Int. Arch. Occup. Environ. Health"},{"key":"10.1016\/j.envint.2026.110374_b0055","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1016\/j.ejogrb.2017.04.029","article-title":"Age-independent anti-Mullerian hormone (AMH) standard deviation scores to estimate ovarian function","volume":"213","author":"Helden","year":"2017","journal-title":"Eur. J. Obstet. Gynecol. Reprod. Biol."},{"key":"10.1016\/j.envint.2026.110374_b0060","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1289\/ehp.7201119","article-title":"Epidemiologic study on yusho, a poisoning caused by ingestion of rice oil contaminated with a commercial brand of polychlorinated biphenyls","volume":"1","author":"Kuratsune","year":"1972","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.envint.2026.110374_b0065","doi-asserted-by":"crossref","first-page":"2264","DOI":"10.1093\/humrep\/dep210","article-title":"N.S on behalf of the ESHRE Special Interest Group for Reproductive Endocrinology\u2014AMH Round Table Anti-Mullerian hormone (AMH): what do we still need to know?","volume":"24","author":"La Marca","year":"2009","journal-title":"Hum. Reprod."},{"key":"10.1016\/j.envint.2026.110374_b0070","doi-asserted-by":"crossref","first-page":"615","DOI":"10.1210\/endo.143.2.8624","article-title":"Ligand activation of the AhR transcription factor drives Bax-dependent apoptosis in developing fetal ovarian germ cells","volume":"143","author":"Matikainen","year":"2002","journal-title":"Endocrinology"},{"key":"10.1016\/j.envint.2026.110374_b0075","doi-asserted-by":"crossref","first-page":"534","DOI":"10.1093\/toxsci\/kfi308","article-title":"In utero and lactational exposure to TCDD; steroidogenic outcomes differ in male and female rat pups","volume":"88","author":"Myllym\u00e4ki","year":"2005","journal-title":"Toxicol. Sci."},{"key":"10.1016\/j.envint.2026.110374_b0080","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0036129","article-title":"Environmentally induced epigenetic transgenerational inheritance of ovarian disease","volume":"7","author":"Nilsson","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.envint.2026.110374_b0085","doi-asserted-by":"crossref","first-page":"1368","DOI":"10.1111\/jog.15972","article-title":"Cut-off value for anti-M\u00fcllerian hormone in the diagnostic criteria for polycystic ovary syndrome in the Japanese population","volume":"50","author":"Noguchi","year":"2024","journal-title":"J. Obstet. Gynaecol. Res."},{"key":"10.1016\/j.envint.2026.110374_b0090","doi-asserted-by":"crossref","DOI":"10.1111\/jog.16152","article-title":"Japan society of obstetrics and gynecology revised diagnostic criteria for polycystic ovary syndrome: JSOG2024 criteria","volume":"51","author":"Noguchi","year":"2025","journal-title":"J. Obstet. Gynaecol. Res."},{"key":"10.1016\/j.envint.2026.110374_b0095","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1186\/s12940-020-00680-0","article-title":"Mortality in Yusho patients exposed to polychlorinated biphenyls and polychlorinated dibenzofurans: a 50-year retrospective cohort study","volume":"19","author":"Onozuka","year":"2020","journal-title":"Environ. Health"},{"key":"10.1016\/j.envint.2026.110374_b0100","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1095\/biolreprod.115.130336","article-title":"Effects of endocrine-disrupting chemicals on the ovary","volume":"93","author":"Patel","year":"2015","journal-title":"Biol. Reprod."},{"key":"10.1016\/j.envint.2026.110374_b0105","doi-asserted-by":"crossref","first-page":"450","DOI":"10.1210\/endo.141.1.7374","article-title":"The aryl hydrocarbon receptor, a basic helix\u2013loop\u2013helix transcription factor of the PAS gene family, is required for normal ovarian germ cell dynamics in the mouse","volume":"141","author":"Robles","year":"2000","journal-title":"Endocrinology"},{"key":"10.1016\/j.envint.2026.110374_b0110","doi-asserted-by":"crossref","first-page":"747","DOI":"10.1016\/j.fertnstert.2010.10.011","article-title":"Age-specific serum anti-M\u00fcllerian hormone values for 17,120 women presenting to fertility centers within the United States","volume":"95","author":"Seifer","year":"2011","journal-title":"Fertil. Steril."},{"key":"10.1016\/j.envint.2026.110374_b0115","doi-asserted-by":"crossref","first-page":"1367","DOI":"10.1001\/jama.2017.14588","article-title":"Association between biomarkers of ovarian reserve and infertility among older women of reproductive age","volume":"318","author":"Steiner","year":"2017","journal-title":"J. Am. Med. Assoc."},{"key":"10.1016\/j.envint.2026.110374_b0120","doi-asserted-by":"crossref","first-page":"1983","DOI":"10.1016\/j.chemosphere.2006.07.069","article-title":"Concentrations of polychlorinated dibenzo-p-dioxins, polychlorinated dibenzofurans, and non-ortho and mono-ortho polychlorinated biphenyls in blood of Yusho patients","volume":"66","author":"Todaka","year":"2007","journal-title":"Chemosphere"},{"key":"10.1016\/j.envint.2026.110374_b0125","first-page":"S95","article-title":"The concepts of the new criteria for Yusho poisoning","volume":"1","author":"Tokunaga","year":"2005","journal-title":"J. Dermatol. Sci. Suppl."},{"key":"10.1016\/j.envint.2026.110374_b0130","doi-asserted-by":"crossref","first-page":"1837","DOI":"10.1093\/humrep\/dem101","article-title":"Stable serum levels of anti-Mullerian hormone during the menstrual cycle: a prospective study in normo-ovulatory women","volume":"22","author":"Tsepelidis","year":"2007","journal-title":"Hum. Reprod."},{"key":"10.1016\/j.envint.2026.110374_b0135","doi-asserted-by":"crossref","first-page":"626","DOI":"10.1289\/ehp.10686","article-title":"Long-term effects of polychlorinated biphenyls and dioxins on pregnancy outcomes in women affected by the Yusho incident","volume":"116","author":"Tsukimori","year":"2008","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.envint.2026.110374_b0140","doi-asserted-by":"crossref","first-page":"928","DOI":"10.1016\/j.chemosphere.2011.06.009","article-title":"Comparison of the concentrations of polychlorinated biphenyls and dioxins in mothers affected by the Yusho incident and their children","volume":"84","author":"Tsukimori","year":"2011","journal-title":"Chemosphere"},{"key":"10.1016\/j.envint.2026.110374_b0145","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1007\/s00204-004-0583-y","article-title":"Erratum to: developmental toxicity of polychlorinated biphenyls (PCBs): a systematic review of experimental data","volume":"78","author":"Ulbrich","year":"2004","journal-title":"Arch. Toxicol."},{"key":"10.1016\/j.envint.2026.110374_b0150","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1289\/ehp.9667","article-title":"Serum dioxin concentrations and quality of ovarian function in women of Seveso","volume":"115","author":"Warner","year":"2007","journal-title":"Environ. Health Perspect."}],"container-title":["Environment International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0160412026003326?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0160412026003326?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T20:05:52Z","timestamp":1785873952000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0160412026003326"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8]]},"references-count":30,"alternative-id":["S0160412026003326"],"URL":"https:\/\/doi.org\/10.1016\/j.envint.2026.110374","relation":{},"ISSN":["0160-4120"],"issn-type":[{"value":"0160-4120","type":"print"}],"subject":[],"published":{"date-parts":[[2026,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Relationship between ovarian reserve and parental exposure in first-generation offspring of Yusho patients","name":"articletitle","label":"Article Title"},{"value":"Environment International","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.envint.2026.110374","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Author(s). Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}],"article-number":"110374"}}