{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T11:40:10Z","timestamp":1793187610109,"version":"4.5.0"},"reference-count":23,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T00:00:00Z","timestamp":1792108800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Environment International"],"published-print":{"date-parts":[[2026,11]]},"DOI":"10.1016\/j.envint.2026.110571","type":"journal-article","created":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T06:27:12Z","timestamp":1792391232000},"page":"110571","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Detection of the PFAS ADV in a non-occupationally exposed population living in Northern Italy"],"prefix":"10.1016","volume":"217","author":[{"given":"Francesca","family":"Coperchini","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"Croce","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simone","family":"Marangoni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesca","family":"Sellaro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5925-1352","authenticated-orcid":false,"given":"Roberta","family":"Pernetti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessia","family":"Greco","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elena","family":"Franchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1665-0625","authenticated-orcid":false,"given":"Marco","family":"Denegri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8503-6560","authenticated-orcid":false,"given":"Enrico","family":"Oddone","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7273-5725","authenticated-orcid":false,"given":"Tiziano","family":"Bonato","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mario","family":"Rotondi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.envint.2026.110571_b0005","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2024.178337","article-title":"Contamination of the terrestrial food chain by per- and polyfluoroalkyl substances (PFAS) and related human health risks: a systematic review","volume":"961","author":"Bonato","year":"2025","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.envint.2026.110571_b0040","doi-asserted-by":"crossref","DOI":"10.1016\/j.chemosphere.2024.142045","article-title":"Chloroperfluoropolyether carboxylate compounds: a review","volume":"357","author":"Bucaletti","year":"2024","journal-title":"Chemosphere"},{"key":"10.1016\/j.envint.2026.110571_b0100","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2019.105048","article-title":"Legacy and alternative per- and polyfluoroalkyl substances in the U.S. general population: paired serum-urine data from the 2013-2014 National Health and Nutrition Examination Survey","volume":"131","author":"Calafat","year":"2019","journal-title":"Environ. Int."},{"issue":"22","key":"10.1016\/j.envint.2026.110571_b0065","doi-asserted-by":"crossref","first-page":"3109","DOI":"10.1002\/1097-0258(20001130)19:22<3109::AID-SIM558>3.0.CO;2-F","article-title":"Sympercents: symmetric percentage differences on the 100 log(e) scale simplify the presentation of log transformed data","volume":"19","author":"Cole","year":"2000","journal-title":"Stat. Med."},{"key":"10.1016\/j.envint.2026.110571_b0030","article-title":"Biochemical and haematological effects of serum PFOA, ADV and cC","volume":"262","author":"Consonni","year":"2024","journal-title":"Int. J. Hyg. Environ. Health"},{"key":"10.1016\/j.envint.2026.110571_b0025","article-title":"Thyroid Disrupting effects of old and new generation PFAS","volume":"11","author":"Coperchini","year":"2020","journal-title":"Front Endocrinol (lausanne)."},{"issue":"8","key":"10.1016\/j.envint.2026.110571_b0010","doi-asserted-by":"crossref","first-page":"1863","DOI":"10.1007\/s40618-024-02339-w","article-title":"Changing the structure of PFOA and PFOS: a chemical industry strategy or a solution to avoid thyroid-disrupting effects?","volume":"47","author":"Coperchini","year":"2024","journal-title":"J. Endocrinol. Invest."},{"key":"10.1016\/j.envint.2026.110571_b0090","unstructured":"Council EPa. Regulation (EC) No 1272\/2008 on classification, labelling and packaging of substances and mixtures (CLP). Official Journal of the European Union; 2008."},{"key":"10.1016\/j.envint.2026.110571_b0085","unstructured":"Council EPa. Regulation (EC) No 1907\/2006 concerning the Registration, Evaluation, Authorisation and Restriction of Chemicals (REACH). Official Journal of the European Union; 2006."},{"key":"10.1016\/j.envint.2026.110571_b0050","doi-asserted-by":"crossref","DOI":"10.1016\/j.jchromb.2025.124738","article-title":"UHPLC-MS\/MS analysis of PFAS in the serum of patients with Alzheimer's disease, mild cognitive impairment and controls: a preliminary study","volume":"1266","author":"Deda","year":"2025","journal-title":"J. Chromatogr. B Anal. Technol. Biomed. Life Sci."},{"issue":"3","key":"10.1016\/j.envint.2026.110571_b0015","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1002\/etc.4935","article-title":"PFAS exposure pathways for humans and wildlife: a synthesis of current knowledge and key gaps in understanding","volume":"40","author":"De Silva","year":"2021","journal-title":"Environ. Toxicol. Chem."},{"key":"10.1016\/j.envint.2026.110571_b0020","doi-asserted-by":"crossref","unstructured":"Evich MG, Davis MJB, McCord JP, Acrey B, Awkerman JA, Knappe DRU, et al. Per- and polyfluoroalkyl substances in the environment. Science. 2022;375(6580):eabg9065.","DOI":"10.1126\/science.abg9065"},{"key":"10.1016\/j.envint.2026.110571_b0060","doi-asserted-by":"crossref","DOI":"10.1016\/j.chemosphere.2022.137530","article-title":"PFAS levels and exposure determinants in sensitive population groups","volume":"313","author":"Fabelova","year":"2023","journal-title":"Chemosphere"},{"issue":"4","key":"10.1016\/j.envint.2026.110571_b0110","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1007\/s00420-006-0136-1","article-title":"Occurrence of perfluorinated substances in an adult German population in southern Bavaria","volume":"80","author":"Fromme","year":"2007","journal-title":"Int Arch Occup Environ Health"},{"key":"10.1016\/j.envint.2026.110571_b0105","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijheh.2016.12.014","article-title":"ADONA and perfluoroalkylated substances in plasma samples of German blood donors living in South Germany","author":"Fromme","year":"2017","journal-title":"Int. J. Hyg. Environ. Health"},{"issue":"4","key":"10.1016\/j.envint.2026.110571_b0035","doi-asserted-by":"crossref","first-page":"518","DOI":"10.1093\/annweh\/wxac095","article-title":"Historical trend of exposure to perfluoroalkyl surfactants PFOA, ADV, and cC6O4 and its management in two perfluoroalkyl polymers plants","volume":"67","author":"Fustinoni","year":"2023","journal-title":"Italy. Ann Work Expo Health."},{"issue":"2","key":"10.1016\/j.envint.2026.110571_b0070","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1093\/oxfordjournals.aje.a114229","article-title":"The fallacy of employing standardized regression coefficients and correlations as measures of effect","volume":"123","author":"Greenland","year":"1986","journal-title":"Am. J. Epidemiol."},{"issue":"5","key":"10.1016\/j.envint.2026.110571_b0075","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1097\/00001648-199109000-00015","article-title":"Standardized regression coefficients: a further critique and review of some alternatives","volume":"2","author":"Greenland","year":"1991","journal-title":"Epidemiology"},{"issue":"3","key":"10.1016\/j.envint.2026.110571_b0055","doi-asserted-by":"crossref","first-page":"865","DOI":"10.1007\/s00216-020-03041-5","article-title":"Comparison of extraction methods for per- and polyfluoroalkyl substances (PFAS) in human serum and placenta samples-insights into extractable organic fluorine (EOF)","volume":"413","author":"Kaiser","year":"2021","journal-title":"Anal. Bioanal. Chem."},{"key":"10.1016\/j.envint.2026.110571_b0045","unstructured":"Legislative Decree No. 102 of 19 June 2025. Supplementary and corrective provisions to Legislative Decree No. 18 of 23 February 2023 implementing Directive (EU) 2020\/2184 on the quality of water intended for human consumption., No. 102 (2025)."},{"key":"10.1016\/j.envint.2026.110571_b0095","unstructured":"Piemonte R. Risultati Biomonitoraggio PFAS in provincia di Alessandria 2025 [Available from: https:\/\/www.regione.piemonte.it\/web\/temi\/sanita\/prevenzione\/risultati-biomonitoraggio-pfas-provincia-alessandria."},{"issue":"21","key":"10.1016\/j.envint.2026.110571_b0115","doi-asserted-by":"crossref","DOI":"10.3390\/ijerph20216984","article-title":"Trends in serum per- and polyfluoroalkyl substance (PFAS) concentrations in teenagers and adults, 1999-2018 NHANES","volume":"20","author":"Sonnenberg","year":"2023","journal-title":"Int. J. Environ. Res. Public Health"},{"key":"10.1016\/j.envint.2026.110571_b0080","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1080\/00031305.2019.1583913","article-title":"Moving to a World beyond \u201c<0.05\u201d","volume":"73","author":"Wasserstein","year":"2019","journal-title":"Am. Stat."}],"container-title":["Environment International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0160412026005295?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0160412026005295?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T11:00:58Z","timestamp":1793185258000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0160412026005295"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,11]]},"references-count":23,"alternative-id":["S0160412026005295"],"URL":"https:\/\/doi.org\/10.1016\/j.envint.2026.110571","relation":{},"ISSN":["0160-4120"],"issn-type":[{"value":"0160-4120","type":"print"}],"subject":[],"published":{"date-parts":[[2026,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Detection of the PFAS ADV in a non-occupationally exposed population living in Northern Italy","name":"articletitle","label":"Article Title"},{"value":"Environment International","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.envint.2026.110571","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Authors. Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}],"article-number":"110571"}}