{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T03:28:16Z","timestamp":1785814096164,"version":"3.56.0"},"reference-count":40,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2016,1,1]],"date-time":"2016-01-01T00:00:00Z","timestamp":1451606400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"name":"National Science and Technology Major Project of China","award":["2013ZX07310-001-04"],"award-info":[{"award-number":["2013ZX07310-001-04"]}]},{"DOI":"10.13039\/501100001809","name":"Natural Science Foundation of China","doi-asserted-by":"crossref","award":["21277049"],"award-info":[{"award-number":["21277049"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Open Research Fund of State Key Laboratory of Estuarine and Coastal Research","award":["SKLEC-KF201311"],"award-info":[{"award-number":["SKLEC-KF201311"]}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Environmental Pollution"],"published-print":{"date-parts":[[2016,1]]},"DOI":"10.1016\/j.envpol.2015.11.010","type":"journal-article","created":{"date-parts":[[2015,11,17]],"date-time":"2015-11-17T16:30:24Z","timestamp":1447777824000},"page":"868-874","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":65,"special_numbering":"PB","title":["Strong lethality and teratogenicity of strobilurins on Xenopus tropicalis embryos: Basing on ten agricultural fungicides"],"prefix":"10.1016","volume":"208","author":[{"given":"Dan","family":"Li","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mengyun","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yongsheng","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huahong","family":"Shi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junliang","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Defu","family":"He","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.envpol.2015.11.010_bib1","first-page":"826","article-title":"Standard guide for conducting the frog embryo teratogenesis assay\u2013Xenopus (FETAX), E1439\u201391","volume":"vol. 11.05","author":"American Society for Testing, Materials (ASTM)","year":"1998"},{"key":"10.1016\/j.envpol.2015.11.010_bib2","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1016\/j.scitotenv.2007.11.031","article-title":"Axial\u2013skeletal defects caused by carbaryl in Xenopus laevis embryos","volume":"392","author":"Bacchettaa","year":"2008","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.envpol.2015.11.010_bib3","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1080\/03601230701316465","article-title":"Review of strobilurin fungicide chemicals","volume":"42","author":"Balba","year":"2007","journal-title":"J.\u00a0Environ. Sci. Health Part B"},{"key":"10.1016\/j.envpol.2015.11.010_bib4","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1002\/ps.520","article-title":"The strobilurin fungicides","volume":"58","author":"Bartlett","year":"2002","journal-title":"Pest Manag. Sci."},{"key":"10.1016\/j.envpol.2015.11.010_bib5","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1007\/s11270-010-0643-2","article-title":"Occurrence of azoxystrobin, propiconazole, and selected other fungicides in US streams, 2005\u20132006","volume":"218","author":"Battaglin","year":"2011","journal-title":"Water Air Soil Pollut."},{"key":"10.1016\/j.envpol.2015.11.010_bib6","doi-asserted-by":"crossref","first-page":"2477","DOI":"10.1002\/etc.297","article-title":"Acute toxicity of fungicide formulations to amphibians at environmentally relevant concentrations","volume":"29","author":"Belden","year":"2010","journal-title":"Environ. Toxicol. Chem."},{"key":"10.1016\/j.envpol.2015.11.010_bib7","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1016\/j.chemosphere.2004.05.009","article-title":"A\u00a0comparison of predicted and measured levels of runoff-related pesticide concentrations in small lowland streams on a landscape level","volume":"58","author":"Berenzen","year":"2005","journal-title":"Chemosphere"},{"key":"10.1016\/j.envpol.2015.11.010_bib8","doi-asserted-by":"crossref","first-page":"2086","DOI":"10.1897\/06-522R.1","article-title":"Acute and chronic toxicity of technical-grade pesticides to glochidia and juveniles of freshwater mussels (Unionidae)","volume":"26","author":"Bringolf","year":"2007","journal-title":"Environ. Toxicol. Chem."},{"key":"10.1016\/j.envpol.2015.11.010_bib9","doi-asserted-by":"crossref","first-page":"1135","DOI":"10.1038\/srep01135","article-title":"Terrestrial pesticide exposure of amphibians: an underestimated cause of global decline?","volume":"3","author":"Br\u00fchl","year":"2013","journal-title":"Sci. Rep."},{"key":"10.1016\/j.envpol.2015.11.010_bib10","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1007\/s11270-009-0135-4","article-title":"Investigation potential water quality impacts of fungicides used to combat soybean rust in Indiana","volume":"207","author":"Deb","year":"2010","journal-title":"Water Air Soil Pollut."},{"key":"10.1016\/j.envpol.2015.11.010_bib11","doi-asserted-by":"crossref","first-page":"486","DOI":"10.1016\/j.reprotox.2011.01.003","article-title":"The agrochemical fungicide triadimefon induces abnormalities in Xenopus laevis embryos","volume":"31","author":"Di Renzo","year":"2010","journal-title":"Reprod. Toxicol."},{"key":"10.1016\/j.envpol.2015.11.010_bib12","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/j.pestbp.2013.04.004","article-title":"Effect of phenylpyrrole fungicide fludioxonil on morphological and physiological characteristics of Sclerotinia sclerotiorum","volume":"106","author":"Duan","year":"2013","journal-title":"Pesticide Biochem. Physiol."},{"key":"10.1016\/j.envpol.2015.11.010_bib13","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1002\/(SICI)1520-6866(2000)20:2<87::AID-TCM4>3.0.CO;2-6","article-title":"Assessing the predictive validity of frog embryo teratogenesis assay-Xenopus (FETAX)","volume":"20","author":"Fort","year":"2000","journal-title":"Teratogen. Carcinog. Mutagen."},{"key":"10.1016\/j.envpol.2015.11.010_bib14","unstructured":"GPEI (The Government of Prince Edward Island) Website, 2015. http:\/\/www.gov.pe.ca\/photos\/original\/elj_swater.pdf."},{"key":"10.1016\/j.envpol.2015.11.010_bib15","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1016\/j.chemosphere.2010.02.021","article-title":"Effects of tributyltin (TBT) on Xenopus tropicalis embryos at environmentally relevant concentrations","volume":"79","author":"Guo","year":"2010","journal-title":"Chemosphere"},{"key":"10.1016\/j.envpol.2015.11.010_bib16","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1007\/s10646-014-1203-0","article-title":"Chronic effects of strobilurin fungicides on development, growth, and mortality of larval Great Plains toads (Bufo cognatus)","volume":"23","author":"Hartman","year":"2014","journal-title":"Ecotoxicology"},{"key":"10.1016\/j.envpol.2015.11.010_bib17","first-page":"6","article-title":"Varieties, markets, formulations and applications of strobilurins fungicides (1)","volume":"12","author":"Hua","year":"2013","journal-title":"Mod. Agrochem."},{"key":"10.1016\/j.envpol.2015.11.010_bib18","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1016\/j.scitotenv.2014.11.086","article-title":"Use of the enhanced frog embryo teratogenesis assay-Xenopus (FETAX) to determine chemically-induced phenotypic effects","volume":"508","author":"Hu","year":"2015","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.envpol.2015.11.010_bib19","doi-asserted-by":"crossref","first-page":"1458","DOI":"10.1007\/s10646-012-0899-y","article-title":"Acute toxicity of three strobilurin fungicide formulations and their active ingredients to tadpoles","volume":"21","author":"Hooser","year":"2012","journal-title":"Ecotoxicology"},{"key":"10.1016\/j.envpol.2015.11.010_bib20","doi-asserted-by":"crossref","first-page":"2477","DOI":"10.1002\/etc.297","article-title":"Acute toxicity of fungicide of formulations to amphibians at environmentally relevant concentrations","volume":"29","author":"Jason","year":"2010","journal-title":"Environ. Toxicol. Chem."},{"key":"10.1016\/j.envpol.2015.11.010_bib21","doi-asserted-by":"crossref","first-page":"1348","DOI":"10.1016\/j.chemosphere.2012.02.026","article-title":"Toxicity of the fungicide trifloxystrobin on tadpoles and its effect on fish-tadpole interaction","volume":"87","author":"Junges","year":"2012","journal-title":"Chemosphere"},{"key":"10.1016\/j.envpol.2015.11.010_bib22","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1016\/j.envpol.2005.07.024","article-title":"The status of pesticide pollution in surface waters (rivers and lakes) of Greece. Part I. Review on occurrence and levels","volume":"141","author":"Konstantinou","year":"2006","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.envpol.2015.11.010_bib23","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1016\/j.scitotenv.2012.09.082","article-title":"Kresoxim methyl deposition, drift and runoff in a vineyard catchment","volume":"442","author":"Lefrancq","year":"2013","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.envpol.2015.11.010_bib24","doi-asserted-by":"crossref","first-page":"2903","DOI":"10.1016\/j.envpol.2009.05.015","article-title":"Amphibians and agriculturalchemicals: review of the risks in a complex environment","volume":"157","author":"Mann","year":"2009","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.envpol.2015.11.010_bib25","series-title":"Normal Table\u00a0of Xenopus laevis (Daudin)","author":"Nieuwkop","year":"1956"},{"key":"10.1016\/j.envpol.2015.11.010_bib26","doi-asserted-by":"crossref","first-page":"1852","DOI":"10.1016\/j.ecoenv.2010.07.017","article-title":"Effects of the fungicide azoxystrobin on Atlanticsalmon (Salmo salar L.) smolt","volume":"73","author":"Olsvik","year":"2010","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.envpol.2015.11.010_bib27","doi-asserted-by":"crossref","first-page":"e7699","DOI":"10.1371\/journal.pone.0007699","article-title":"Why amphibians are more sensitive than mammals to xenobiotics","volume":"4","author":"Quaranta","year":"2009","journal-title":"Plos One"},{"key":"10.1016\/j.envpol.2015.11.010_bib28","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1016\/j.chemosphere.2012.04.023","article-title":"Occurrence of boscalid and other selected fungicides in surface water and groundwater in three targeted use areas in the United States","volume":"89","author":"Reilly","year":"2012","journal-title":"Chemosphere"},{"key":"10.1016\/j.envpol.2015.11.010_bib29","doi-asserted-by":"crossref","first-page":"2004","DOI":"10.1897\/09-021.1","article-title":"The toxicity of roundup original max to 13 species of larval amphibians","volume":"28","author":"Relyea","year":"2009","journal-title":"Environ. Toxicol. Chem."},{"key":"10.1016\/j.envpol.2015.11.010_bib30","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/j.envint.2012.12.005","article-title":"Occurrence, fate and effects of azoxystrobin in aquatic ecosystems: a review","volume":"53","author":"Rodrigues","year":"2013","journal-title":"Environ. Int."},{"key":"10.1016\/j.envpol.2015.11.010_bib31","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1016\/j.marpolbul.2013.05.028","article-title":"Environmental fate of fungicides and other current-use pesticides in a central California estuary","volume":"73","author":"Smalling","year":"2013","journal-title":"Mar. Pollut. Bull."},{"key":"10.1016\/j.envpol.2015.11.010_bib32","doi-asserted-by":"crossref","first-page":"e1636","DOI":"10.1371\/journal.pone.0001636","article-title":"Measuring the meltdown: drivers of global amphibian extinction and decline","volume":"3","author":"Sodhi","year":"2008","journal-title":"Plos One"},{"key":"10.1016\/j.envpol.2015.11.010_bib33","doi-asserted-by":"crossref","first-page":"1783","DOI":"10.1126\/science.1103538","article-title":"Status and trends of amphibian declines and extinctions worldwide","volume":"306","author":"Stuart","year":"2004","journal-title":"Science"},{"key":"10.1016\/j.envpol.2015.11.010_bib34","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1094\/PDIS-03-12-0322-RE","article-title":"Differential effect of SdhB gene mutations on the sensitivity to SDHI fungicides in Botrytis cinerea","volume":"97","author":"Veloukas","year":"2013","journal-title":"Plant Dis."},{"key":"10.1016\/j.envpol.2015.11.010_bib35","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1016\/j.chemosphere.2012.02.086","article-title":"Toxicity assessment of 45 pesticides to the epigeic earthworm Eisenia fetida","volume":"88","author":"Wang","year":"2012","journal-title":"Chemosphere"},{"key":"10.1016\/j.envpol.2015.11.010_bib36","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1897\/08-279.1","article-title":"Clonal variation in physiological responses of Daphnla magna to the strobilurin fungicide azoxystrobin","volume":"28","author":"Warming","year":"2009","journal-title":"Environ. Toxicol. Chem."},{"key":"10.1016\/j.envpol.2015.11.010_bib37","doi-asserted-by":"crossref","first-page":"1287","DOI":"10.1002\/dvdy.21967","article-title":"Simple vertebrate models for chemical genetics and drug discovery screens: lessons from zebrafish and Xenopus","volume":"238","author":"Wheeler","year":"2009","journal-title":"Dev. Dyn."},{"key":"10.1016\/j.envpol.2015.11.010_bib38","doi-asserted-by":"crossref","first-page":"380","DOI":"10.1007\/s00244-011-9710-y","article-title":"Environmental fate of fungicides in surface waters of a horticultural-production catchment in southeastern Australia","volume":"62","author":"Wightwick","year":"2012","journal-title":"Arch. Environ. Contam. Toxicol."},{"key":"10.1016\/j.envpol.2015.11.010_bib39","doi-asserted-by":"crossref","first-page":"2486","DOI":"10.1242\/jeb.02280","article-title":"Water vapour absorption in the penicillate millipede Polyxenus lagurus (Diplopoda: Penicillata: Polyxenida): microcalorimetric analysis of uptake kinetics","volume":"209","author":"Wright","year":"2006","journal-title":"J.\u00a0Exp. Biol."},{"key":"10.1016\/j.envpol.2015.11.010_bib40","first-page":"145","article-title":"The overview of 2013 China pesticide industry and the prediction and analysis of industrial development in 2014","volume":"53","author":"Yang","year":"2014","journal-title":"Agrochemicals"}],"container-title":["Environmental Pollution"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0269749115301706?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0269749115301706?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,9,1]],"date-time":"2019-09-01T12:44:59Z","timestamp":1567341899000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0269749115301706"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,1]]},"references-count":40,"alternative-id":["S0269749115301706"],"URL":"https:\/\/doi.org\/10.1016\/j.envpol.2015.11.010","relation":{},"ISSN":["0269-7491"],"issn-type":[{"value":"0269-7491","type":"print"}],"subject":[],"published":{"date-parts":[[2016,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Strong lethality and teratogenicity of strobilurins on Xenopus tropicalis embryos: Basing on ten agricultural fungicides","name":"articletitle","label":"Article Title"},{"value":"Environmental Pollution","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.envpol.2015.11.010","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}