{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T10:16:35Z","timestamp":1790504195862,"version":"4.1.0"},"reference-count":38,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2018,3,1]],"date-time":"2018-03-01T00:00:00Z","timestamp":1519862400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,3,1]],"date-time":"2018-03-01T00:00:00Z","timestamp":1519862400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100005416","name":"Norwegian Research Council","doi-asserted-by":"publisher","award":["223268\/F50"],"award-info":[{"award-number":["223268\/F50"]}],"id":[{"id":"10.13039\/501100005416","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Environmental Pollution"],"published-print":{"date-parts":[[2018,3]]},"DOI":"10.1016\/j.envpol.2017.12.023","type":"journal-article","created":{"date-parts":[[2017,12,21]],"date-time":"2017-12-21T04:18:49Z","timestamp":1513829929000},"page":"855-863","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":31,"special_numbering":"C","title":["Parental exposure to gamma radiation causes progressively altered transcriptomes linked to adverse effects in zebrafish offspring"],"prefix":"10.1016","volume":"234","author":[{"given":"Selma","family":"Hurem","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leonardo Mart\u00edn","family":"Mart\u00edn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7759-8202","authenticated-orcid":false,"given":"Leif","family":"Lindeman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dag Anders","family":"Brede","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brit","family":"Salbu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jan Ludvig","family":"Lyche","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4618-5288","authenticated-orcid":false,"given":"Peter","family":"Alestr\u00f6m","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7984-0229","authenticated-orcid":false,"given":"Jorke H.","family":"Kamstra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.envpol.2017.12.023_bib1","doi-asserted-by":"crossref","first-page":"1328","DOI":"10.1101\/gr.116012.110","article-title":"Zebrafish mRNA sequencing deciphers novelties in transcriptome dynamics during maternal to zygotic transition","volume":"21","author":"Aanes","year":"2011","journal-title":"Genome Res."},{"key":"10.1016\/j.envpol.2017.12.023_bib2","doi-asserted-by":"crossref","first-page":"2137","DOI":"10.1016\/j.biocel.2004.02.007","article-title":"Transferrin receptor 1","volume":"36","author":"Aisen","year":"2004","journal-title":"Int. J. Biochem. Cell Biol."},{"key":"10.1016\/j.envpol.2017.12.023_bib3","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1016\/j.jenvrad.2014.07.014","article-title":"Effects of chronic gamma irradiation: a multigenerational study using Caenorhabditis elegans","volume":"137","author":"Buisset-Goussen","year":"2014","journal-title":"J.\u00a0Environ. Radioact."},{"key":"10.1016\/j.envpol.2017.12.023_bib4","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/j.canlet.2013.10.020","article-title":"Embryos of the zebrafish Danio rerio in studies of non-targeted effects of ionizing radiation","volume":"356","author":"Choi","year":"2015","journal-title":"Cancer Lett."},{"key":"10.1016\/j.envpol.2017.12.023_bib5","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/S0892-0362(98)00039-7","article-title":"Effect of late Fetal irradiation on adult behavior of mouse: dose-response relationship","volume":"21","author":"Devi","year":"1999","journal-title":"Neurotoxicol. Teratol."},{"key":"10.1016\/j.envpol.2017.12.023_bib6","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1093\/bioinformatics\/bts635","article-title":"STAR: ultrafast universal RNA-seq aligner","volume":"29","author":"Dobin","year":"2013","journal-title":"Bioinformatics"},{"key":"10.1016\/j.envpol.2017.12.023_bib7","doi-asserted-by":"crossref","first-page":"2843","DOI":"10.1182\/blood-2008-06-165340","article-title":"Transferrin-a modulates hepcidin expression in zebrafish embryos","volume":"113","author":"Fraenkel","year":"2009","journal-title":"Blood"},{"key":"10.1016\/j.envpol.2017.12.023_bib8","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3389\/fgene.2014.00268","article-title":"Embryonic ionizing radiation exposure results in expression alterations of genes associated with cardiovascular and neurological development, function, and disease and modified cardiovascular function in zebrafish","volume":"5","author":"Freeman","year":"2014","journal-title":"Front. Genet."},{"key":"10.1016\/j.envpol.2017.12.023_bib9","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1038\/nature12974","article-title":"Two independent transcription initiation codes overlap on vertebrate core promoters","volume":"507","author":"Haberle","year":"2014","journal-title":"Nature"},{"key":"10.1016\/j.envpol.2017.12.023_bib10","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/j.mrrev.2017.01.001","article-title":"Ionizing radiation biomarkers in epidemiological studies \u2013 an update","volume":"771","author":"Hall","year":"2017","journal-title":"Mutat. Res. Mutat. Res."},{"key":"10.1016\/j.envpol.2017.12.023_bib11","series-title":"Advances in Biomedical Sciences and Engineering","first-page":"204","article-title":"Response of cells to ionizing radiation","author":"Han","year":"2012"},{"key":"10.1016\/j.envpol.2017.12.023_bib12","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1097\/01.HP.0000281179.03443.2e","article-title":"Radiation-induced effects on plants and animals: findings of the United Nations Chernobyl Forum","volume":"93","author":"Hinton","year":"2007","journal-title":"Health Phys."},{"key":"10.1016\/j.envpol.2017.12.023_bib13","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1016\/j.ijdevneu.2005.01.006","article-title":"Late effect of prenatal irradiation on the hippocampal histology and brain weight in adult mice","volume":"23","author":"Hossain","year":"2005","journal-title":"Int. J. Dev. Neurosci."},{"key":"10.1016\/j.envpol.2017.12.023_bib14","doi-asserted-by":"crossref","first-page":"564","DOI":"10.1016\/j.envres.2017.07.053","article-title":"Parental gamma irradiation induces reprotoxic effects accompanied by genomic instability in zebrafish (Danio rerio) embryos","volume":"159","author":"Hurem","year":"2017","journal-title":"Environ. Res."},{"key":"10.1016\/j.envpol.2017.12.023_bib15","doi-asserted-by":"crossref","DOI":"10.1016\/j.ecoenv.2018.02.031","article-title":"Gamma irradiation during gametogenesis in young adult zebrafish causes persistent genotoxicity and adverse reproductive effects","author":"Hurem","year":"2018","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.envpol.2017.12.023_bib16","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0179259","article-title":"Dose-dependent effects of gamma radiation on the early zebrafish development and gene expression","volume":"12","author":"Hurem","year":"2017","journal-title":"PLoS One"},{"key":"10.1016\/j.envpol.2017.12.023_bib17","doi-asserted-by":"crossref","first-page":"1277","DOI":"10.1021\/es505064d","article-title":"Radiological dose rates to marine fish from the fukushima daiichi accident: the first three years across the north pacific","volume":"49","author":"Johansen","year":"2015","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.envpol.2017.12.023_bib18","doi-asserted-by":"crossref","first-page":"e69445","DOI":"10.1371\/journal.pone.0069445","article-title":"Long-term effects of ionizing radiation on gene expression in a zebrafish model","volume":"8","author":"Jaafar","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.envpol.2017.12.023_bib19","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1186\/s13072-017-0126-4","article-title":"Differential DNA methylation at conserved non-genic elements and evidence for transgenerational inheritance following developmental exposure to mono(2-ethylhexyl) phthalate and 5-azacytidine in zebrafish","volume":"10","author":"Kamstra","year":"2017","journal-title":"Epigenetics Chromatin"},{"key":"10.1016\/j.envpol.2017.12.023_bib20","first-page":"1","article-title":"Targeting ATM pathway for therapeutic intervention in cancer","author":"Khalil","year":"2012","journal-title":"Biodiscovery"},{"key":"10.1016\/j.envpol.2017.12.023_bib21","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1002\/aja.1002030302","article-title":"Stages of embryonic development of the zebrafish","volume":"203","author":"Kimmel","year":"1995","journal-title":"Dev. Dyn."},{"key":"10.1016\/j.envpol.2017.12.023_bib22","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1016\/j.biocel.2014.01.012","article-title":"Chromatin structure and radiation-induced DNA damage: from structural biology to radiobiology","volume":"49","author":"Lavelle","year":"2014","journal-title":"Int. J. Biochem. Cell Biol."},{"key":"10.1016\/j.envpol.2017.12.023_bib23","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1007\/s00128-016-2006-1","article-title":"Single low-dose ionizing radiation induces genotoxicity in adult zebrafish and its non-irradiated progeny","volume":"98","author":"Lemos","year":"2017","journal-title":"Bull. Environ. Contam. Toxicol."},{"key":"10.1016\/j.envpol.2017.12.023_bib24","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1016\/j.jhazmat.2016.06.020","article-title":"Radioactively contaminated areas: bioindicator species and biomarkers of effect in an early warning scheme for a preliminary risk assessment","volume":"317","author":"Louren\u00e7o","year":"2016","journal-title":"J.\u00a0Hazard. Mater"},{"key":"10.1016\/j.envpol.2017.12.023_bib25","doi-asserted-by":"crossref","first-page":"550","DOI":"10.1186\/s13059-014-0550-8","article-title":"Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2","volume":"15","author":"Love","year":"2014","journal-title":"Genome Biol."},{"key":"10.1016\/j.envpol.2017.12.023_bib26","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3389\/fgene.2013.00040","article-title":"Epigenetics in radiation biology: a new research frontier","volume":"4","author":"Merrifield","year":"2013","journal-title":"Front. Genet."},{"key":"10.1016\/j.envpol.2017.12.023_bib27","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1101\/gad.1863810","article-title":"Essential role of Tip60-dependent recruitment of ribonucleotide reductase at DNA damage sites in DNA repair during G1 phase","volume":"24","author":"Niida","year":"2010","journal-title":"Genes Dev."},{"key":"10.1016\/j.envpol.2017.12.023_bib28","doi-asserted-by":"crossref","first-page":"674","DOI":"10.1093\/jrr\/rru007","article-title":"Profiling of low molecular weight proteins in plasma from locally irradiated individuals","volume":"55","author":"Nylund","year":"2014","journal-title":"J.\u00a0Radiat. Res."},{"key":"10.1016\/j.envpol.2017.12.023_bib29","doi-asserted-by":"crossref","first-page":"3861","DOI":"10.1242\/jcs.00059","article-title":"Fibronectin at a glance","volume":"115","author":"Pankov","year":"2002","journal-title":"J.\u00a0Cell Sci."},{"key":"10.1016\/j.envpol.2017.12.023_bib30","doi-asserted-by":"crossref","first-page":"662","DOI":"10.1016\/j.tcb.2010.08.011","article-title":"Histone demethylases in development and disease","volume":"20","author":"Pedersen","year":"2010","journal-title":"Trends Cell Biol."},{"key":"10.1016\/j.envpol.2017.12.023_bib31","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1016\/S0304-3940(02)01423-4","article-title":"Assumption-free analysis of quantitative real-time polymerase chain reaction (PCR) data","volume":"339","author":"Ramakers","year":"2003","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.envpol.2017.12.023_bib32","first-page":"787","article-title":"Summary of information on the effects of ionizing and non-ionizing radiation on cytochrome P450 and other drug metabolizing enzymes and transporters. Curr","volume":"13","author":"Rendic","year":"2012","journal-title":"Drug Metab."},{"key":"10.1016\/j.envpol.2017.12.023_bib33","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1002\/bies.201300113","article-title":"A\u00a0paternal environmental legacy: evidence for epigenetic inheritance through the male germ line","volume":"36","author":"Soubry","year":"2014","journal-title":"BioEssays"},{"key":"10.1016\/j.envpol.2017.12.023_bib34","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1289\/ehp.9087291","article-title":"Iron, radiation, and cancer","volume":"87","author":"Stevens","year":"1990","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.envpol.2017.12.023_bib35","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1021\/ez500019j","article-title":"Assessment of fukushima-derived radiation doses and effects on wildlife in Japan","volume":"1","author":"Strand","year":"2014","journal-title":"Environ. Sci. Technol. Lett."},{"key":"10.1016\/j.envpol.2017.12.023_bib36","doi-asserted-by":"crossref","first-page":"1","DOI":"10.2131\/jts.41.1","article-title":"Xenobiotic metabolism in the zebrafish: a review of the spatiotemporal distribution, modulation and activity of Cytochrome P450 families 1 to 3","volume":"41","author":"Saad","year":"2016","journal-title":"J.\u00a0Toxicol. Sci."},{"key":"10.1016\/j.envpol.2017.12.023_bib37","series-title":"Report of the United Nations Scientific Committee on the Effects of Atomic Radiation 2010 UNSCEAR 2010 Report","author":"Unscear","year":"2010"},{"key":"10.1016\/j.envpol.2017.12.023_bib38","doi-asserted-by":"crossref","DOI":"10.1186\/gb-2002-3-7-research0034","article-title":"Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes","volume":"3","author":"Vandesompele","year":"2002","journal-title":"Genome Biol."}],"container-title":["Environmental Pollution"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0269749117333687?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0269749117333687?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,2]],"date-time":"2025-10-02T20:47:58Z","timestamp":1759438078000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0269749117333687"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,3]]},"references-count":38,"alternative-id":["S0269749117333687"],"URL":"https:\/\/doi.org\/10.1016\/j.envpol.2017.12.023","relation":{},"ISSN":["0269-7491"],"issn-type":[{"value":"0269-7491","type":"print"}],"subject":[],"published":{"date-parts":[[2018,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Parental exposure to gamma radiation causes progressively altered transcriptomes linked to adverse effects in zebrafish offspring","name":"articletitle","label":"Article Title"},{"value":"Environmental Pollution","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.envpol.2017.12.023","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}