{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T17:34:18Z","timestamp":1791480858334,"version":"4.3.4"},"reference-count":73,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2018,5,1]],"date-time":"2018-05-01T00:00:00Z","timestamp":1525132800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,5,1]],"date-time":"2018-05-01T00:00:00Z","timestamp":1525132800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2019,3,7]],"date-time":"2019-03-07T00:00:00Z","timestamp":1551916800000},"content-version":"am","delay-in-days":310,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,5,1]],"date-time":"2018-05-01T00:00:00Z","timestamp":1525132800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2018,5,1]],"date-time":"2018-05-01T00:00:00Z","timestamp":1525132800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2018,5,1]],"date-time":"2018-05-01T00:00:00Z","timestamp":1525132800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2018,5,1]],"date-time":"2018-05-01T00:00:00Z","timestamp":1525132800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2018,5,1]],"date-time":"2018-05-01T00:00:00Z","timestamp":1525132800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100005825","name":"National Institute of Food and Agriculture, U.S. Department of Agriculture","doi-asserted-by":"publisher","award":["2016-68003-24601"],"award-info":[{"award-number":["2016-68003-24601"]}],"id":[{"id":"10.13039\/100005825","id-type":"DOI","asserted-by":"publisher"}]},{"name":"New York State Pollution Prevention Institute"},{"DOI":"10.13039\/100000001","name":"National Science Foundation","doi-asserted-by":"publisher","award":["1102998"],"award-info":[{"award-number":["1102998"]}],"id":[{"id":"10.13039\/100000001","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Environmental Pollution"],"published-print":{"date-parts":[[2018,5]]},"DOI":"10.1016\/j.envpol.2018.02.024","type":"journal-article","created":{"date-parts":[[2018,3,7]],"date-time":"2018-03-07T21:37:09Z","timestamp":1520458629000},"page":"764-772","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":150,"special_numbering":"C","title":["Occurrence and transformation of veterinary antibiotics and antibiotic resistance genes in dairy manure treated by advanced anaerobic digestion and conventional treatment methods"],"prefix":"10.1016","volume":"236","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4104-0936","authenticated-orcid":false,"given":"Joshua S.","family":"Wallace","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emily","family":"Garner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amy","family":"Pruden","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Diana S.","family":"Aga","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.envpol.2018.02.024_bib1","first-page":"560","article-title":"Effect of urea on the epimerisation of chlortetracycline hydrochloride by UV light","volume":"47","author":"Agostini","year":"1972","journal-title":"Pharm. Acta Helv."},{"key":"10.1016\/j.envpol.2018.02.024_bib2","doi-asserted-by":"crossref","first-page":"8581","DOI":"10.1016\/j.biortech.2010.06.075","article-title":"The effect and fate of antibiotics during the anaerobic digestion of pig manure","volume":"101","author":"Alvarez","year":"2010","journal-title":"Bioresour. Technol."},{"key":"10.1016\/j.envpol.2018.02.024_bib3","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1111\/j.1574-6968.2007.00757.x","article-title":"Evolution and ecology of antibiotic resistance genes","volume":"271","author":"Aminov","year":"2007","journal-title":"FEMS Microbiol. Lett."},{"key":"10.1016\/j.envpol.2018.02.024_bib4","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/j.chroma.2005.04.013","article-title":"Complexities in tetracycline analysis\u2014chemistry, matrix extraction, cleanup, and liquid chromatography","volume":"1075","author":"Anderson","year":"2005","journal-title":"J.\u00a0Chromatogr. A"},{"key":"10.1016\/j.envpol.2018.02.024_bib5","doi-asserted-by":"crossref","first-page":"2377","DOI":"10.1016\/j.watres.2008.01.005","article-title":"Effect of the presence of the antimicrobial tylosin in swine waste on anaerobic treatment","volume":"42","author":"Angenent","year":"2008","journal-title":"Water Res."},{"key":"10.1016\/j.envpol.2018.02.024_bib6","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1016\/j.jhazmat.2008.01.096","article-title":"Degradation and metabolization of chlortetracycline during the anaerobic digestion of manure from medicated calves","volume":"158","author":"Arikan","year":"2008","journal-title":"J.\u00a0Haz. Mater."},{"key":"10.1016\/j.envpol.2018.02.024_bib7","doi-asserted-by":"crossref","first-page":"1637","DOI":"10.1016\/j.procbio.2006.03.010","article-title":"The fate and effect of oxytetracycline during the anaerobic digestion of manure from therapeutically treated calves","volume":"41","author":"Arikan","year":"2006","journal-title":"Process Biochem."},{"key":"10.1016\/j.envpol.2018.02.024_bib8","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/j.apenergy.2014.02.035","article-title":"Pretreatment methods to enhance anaerobic digestion of organic solid waste","volume":"123","author":"Ariunbaatar","year":"2014","journal-title":"Appl. Energy"},{"key":"10.1016\/j.envpol.2018.02.024_bib9","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1016\/j.tim.2006.02.006","article-title":"Co-selection of antibiotic and metal resistance","volume":"14","author":"Baker-Austin","year":"2006","journal-title":"Trends Microbiol."},{"issue":"Suppl.\u00a01","key":"10.1016\/j.envpol.2018.02.024_bib10","first-page":"S347","article-title":"Plasmid encoded antibiotic resistance: acquisition and transfer of antibiotic resistance genes in bacteria","volume":"153","author":"Bennett","year":"2008","journal-title":"Br. J. Pharmacol."},{"key":"10.1016\/j.envpol.2018.02.024_bib11","series-title":"Dairy Waste Anaerobic Digestion Handbook","first-page":"1","author":"Burke","year":"2001"},{"key":"10.1016\/j.envpol.2018.02.024_bib12","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1016\/j.livsci.2007.09.004","article-title":"Pharmaceutica acta helvetiae","volume":"112","author":"Burton","year":"2007","journal-title":"Livest. Sci."},{"key":"10.1016\/j.envpol.2018.02.024_bib13","doi-asserted-by":"crossref","first-page":"2959","DOI":"10.1016\/j.watres.2013.02.053","article-title":"Chronic impact of tetracycline on the biodegradation of an organic substrate mixture under anaerobic conditions","volume":"47","author":"Cetecioglu","year":"2013","journal-title":"Water Res."},{"key":"10.1016\/j.envpol.2018.02.024_bib14","doi-asserted-by":"crossref","first-page":"779","DOI":"10.1016\/j.chemosphere.2010.03.020","article-title":"Adsorption and transformation of tetracycline antibiotics with aluminum oxide","volume":"79","author":"Chen","year":"2010","journal-title":"Chemosphere"},{"key":"10.1016\/j.envpol.2018.02.024_bib15","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1016\/j.chemosphere.2008.06.026","article-title":"Determination of the persistence of pharmaceuticals in biosolids using liquid-chromatography tandem mass spectrometry","volume":"73","author":"Chenxi","year":"2008","journal-title":"Chemosphere"},{"key":"10.1016\/j.envpol.2018.02.024_bib16","doi-asserted-by":"crossref","first-page":"528","DOI":"10.2460\/javma.235.5.528","article-title":"Update on drugs prohibited from extralabel use in food animals","volume":"235","author":"Davis","year":"2009","journal-title":"J.\u00a0Am. Vet. Med. Assoc."},{"key":"10.1016\/j.envpol.2018.02.024_bib17","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1016\/j.watres.2016.02.049","article-title":"Co-occurrence of integrase 1, antibiotic and heavy metal resistance genes in municipal wastewater treatment plants","volume":"94","author":"Di Cesare","year":"2016","journal-title":"Water Res."},{"key":"10.1016\/j.envpol.2018.02.024_bib18","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1016\/j.trac.2007.04.004","article-title":"Recent advances in LC-MS residue analysis of veterinary medicines in the terrestrial environment","volume":"26","author":"D\u00edaz-Cruz","year":"2007","journal-title":"TrAC Trends Anal. Chem."},{"key":"10.1016\/j.envpol.2018.02.024_bib19","doi-asserted-by":"crossref","first-page":"1245","DOI":"10.2134\/jeq2007.0399","article-title":"Antibiotic degradation during manure composting","volume":"37","author":"Dolliver","year":"2008","journal-title":"J.\u00a0Environ. Qual."},{"key":"10.1016\/j.envpol.2018.02.024_bib20","doi-asserted-by":"crossref","first-page":"2643","DOI":"10.1021\/es404988k","article-title":"Effect of manure application on abundance of antibiotic resistance genes and their attenuation rates in soil: field-scale mass balance approach","volume":"48","author":"Fahrenfeld","year":"2014","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.envpol.2018.02.024_bib21","doi-asserted-by":"crossref","first-page":"1008","DOI":"10.1016\/j.trac.2008.10.001","article-title":"Identification and determination of metabolites and degradation products of sulfonamide antibiotics","volume":"27","author":"Garc\u00eda-Gal\u00e1n","year":"2008","journal-title":"TrAC, Trends Anal. Chem."},{"key":"10.1016\/j.envpol.2018.02.024_bib22","doi-asserted-by":"crossref","first-page":"5417","DOI":"10.1016\/j.biortech.2008.11.012","article-title":"Enhanced solid-liquid separation of dairy manure with natural flocculants","volume":"100","author":"Garcia","year":"2009","journal-title":"Bioresour. Technol."},{"key":"10.1016\/j.envpol.2018.02.024_bib23","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1038\/ismej.2007.31","article-title":"The effects of subtherapeutic antibiotic use in farm animals on the proliferation and persistence of antibiotic resistance among soil bacteria","volume":"1","author":"Ghosh","year":"2007","journal-title":"ISME J."},{"key":"10.1016\/j.envpol.2018.02.024_bib24","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1016\/j.mib.2011.04.009","article-title":"Antibiotic resistance gene spread due to manure application on agricultural fields","volume":"14","author":"Heuer","year":"2011","journal-title":"Curr. Opin. Microbiol."},{"key":"10.1016\/j.envpol.2018.02.024_bib25","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1111\/j.1462-2920.2006.01185.x","article-title":"Manure and sulfadiazine synergistically increased bacterial antibiotic resistance in soil over at least two months","volume":"9","author":"Heuer","year":"2007","journal-title":"Environ. Microbiol."},{"key":"10.1016\/j.envpol.2018.02.024_bib26","doi-asserted-by":"crossref","first-page":"2992","DOI":"10.1016\/j.envpol.2010.05.023","article-title":"Occurrence and source analysis of typical veterinary antibiotics in manure, soil, vegetables and groundwater from organic vegetable bases, northern China","volume":"158","author":"Hu","year":"2010","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.envpol.2018.02.024_bib27","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1016\/j.psep.2014.04.004","article-title":"Fate of trace tetracycline with resistant bacteria and resistance genes in an improved AAO wastewater treatment plant","volume":"93","author":"Huang","year":"2015","journal-title":"Process Saf. Environ. Prot."},{"key":"10.1016\/j.envpol.2018.02.024_bib28","series-title":"Management of Dairy Cattle Manure, Agricultural Uses of Municipal Animal and Industrial Byproducts","first-page":"91","author":"Hubbard","year":"1998"},{"key":"10.1016\/j.envpol.2018.02.024_bib29","doi-asserted-by":"crossref","first-page":"4655","DOI":"10.1016\/j.chroma.2009.03.073","article-title":"Simultaneous determination of tetracyclines and their degradation products in environmental waters by liquid chromatography-electrospray tandem mass spectrometry","volume":"1216","author":"Jia","year":"2009","journal-title":"J.\u00a0Chromatogr. A"},{"key":"10.1016\/j.envpol.2018.02.024_bib30","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1111\/j.1365-2672.1993.tb03000.x","article-title":"The effect of slurry storage and anaerobic digestion on survival of pathogenic bacteria","volume":"74","author":"Kearney","year":"1993","journal-title":"J.\u00a0Appl. Bacteriol."},{"key":"10.1016\/j.envpol.2018.02.024_bib31","first-page":"1129","article-title":"Agricultural use of antibiotics and the evolution and transfer of antibiotic-resistant bacteria","volume":"159","author":"Khachatourians","year":"1998","journal-title":"Can. Med. Assoc. J."},{"key":"10.1016\/j.envpol.2018.02.024_bib32","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1007\/s11270-010-0412-2","article-title":"Occurrence and environmental fate of veterinary antibiotics in the terrestrial environment","volume":"214","author":"Kim","year":"2011","journal-title":"Air Soil. Water Res."},{"key":"10.1016\/j.envpol.2018.02.024_bib33","doi-asserted-by":"crossref","first-page":"5816","DOI":"10.1021\/es050006u","article-title":"Removal of antibiotics in wastewater: effect of hydraulic and solid retention times on the fate of tetracycline in the activated sludge process","volume":"39","author":"Kim","year":"2005","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.envpol.2018.02.024_bib34","doi-asserted-by":"crossref","first-page":"3468","DOI":"10.1021\/es903490h","article-title":"Biodegradation and adsorption of antibiotics in the activated sludge process","volume":"44","author":"Li","year":"2010","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.envpol.2018.02.024_bib35","doi-asserted-by":"crossref","first-page":"1284","DOI":"10.1016\/j.chemosphere.2011.03.002","article-title":"Mass flows and removal of antibiotics in two municipal wastewater treatment plants","volume":"83","author":"Li","year":"2011","journal-title":"Chemosphere"},{"key":"10.1016\/j.envpol.2018.02.024_bib36","doi-asserted-by":"crossref","first-page":"378","DOI":"10.2134\/jeq2007.0230","article-title":"Effects of ionic strength, temperature, and pH on degradation of selected antibiotics","volume":"37","author":"Loftin","year":"2008","journal-title":"J.\u00a0Environ. Qual."},{"key":"10.1016\/j.envpol.2018.02.024_bib37","doi-asserted-by":"crossref","first-page":"570","DOI":"10.1016\/j.envpol.2006.11.035","article-title":"Environmental monitoring study of selected veterinary antibiotics in animal manure and soils in Austria","volume":"148","author":"Martinez-Carballo","year":"2007","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.envpol.2018.02.024_bib38","doi-asserted-by":"crossref","first-page":"2893","DOI":"10.1016\/j.envpol.2009.05.051","article-title":"Environmental pollution by antibiotics and by antibiotic resistance determinants","volume":"157","author":"Martinez","year":"2009","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.envpol.2018.02.024_bib39","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1016\/j.rser.2014.04.039","article-title":"A\u00a0critical review on anaerobic co-digestion achievements between 2010 and 2013","volume":"36","author":"Mata-Alvarez","year":"2014","journal-title":"Renew. Sustain. Energy Rev."},{"key":"10.1016\/j.envpol.2018.02.024_bib40","doi-asserted-by":"crossref","first-page":"2849","DOI":"10.1021\/ja01568a050","article-title":"Studies of the reversible epimerization occurring in the tetracycline family. The preparation, properties and proof of structure of some 4-epi-tetracyclines","volume":"79","author":"McCormick","year":"1957","journal-title":"J.\u00a0Am. Chem. Soc."},{"key":"10.1016\/j.envpol.2018.02.024_bib41","doi-asserted-by":"crossref","first-page":"6102","DOI":"10.1021\/es9038165","article-title":"tet and sul antibiotic resistance genes in livestock lagoons of various operation type, configuration and antibiotic occurrence","volume":"44","author":"McKinney","year":"2010","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.envpol.2018.02.024_bib42","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/S0960-8524(02)00047-0","article-title":"Separation efficiency and particle size distribution in relation to manure type and storage conditions","volume":"85","author":"M\u00f8ller","year":"2002","journal-title":"Bioresour. Technol."},{"key":"10.1016\/j.envpol.2018.02.024_bib43","doi-asserted-by":"crossref","first-page":"827","DOI":"10.1016\/j.scitotenv.2016.01.084","article-title":"Chemical and biological assessment of endocrine disrupting chemicals in a full scal dairy manure anaerobic digester with pasteurization pretreatment","volume":"550","author":"Noguera-Oviedo","year":"2016","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.envpol.2018.02.024_bib44","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1038\/35012500","article-title":"Lateral gene transfer and the nature of bacterial innovation","volume":"405","author":"Ochman","year":"2000","journal-title":"Nature"},{"key":"10.1016\/j.envpol.2018.02.024_bib45","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1016\/j.chemosphere.2011.03.022","article-title":"Residual veterinary antibiotics in swine manure from concentrated animal feeding operations in Shandong Province, China","volume":"84","author":"Pan","year":"2011","journal-title":"Chemosphere"},{"key":"10.1016\/j.envpol.2018.02.024_bib46","doi-asserted-by":"crossref","first-page":"28","DOI":"10.2460\/javma.1999.215.01.28","article-title":"Drugs prohibited from extralabel use in food animals","volume":"215","author":"Payne","year":"1999","journal-title":"J.\u00a0Am. Vet. Med. Assoc."},{"key":"10.1016\/j.envpol.2018.02.024_bib47","doi-asserted-by":"crossref","first-page":"7445","DOI":"10.1021\/es060413l","article-title":"Antibiotic resistance genes as emerging contaminants: studies in northern Colorado","volume":"40","author":"Pruden","year":"2006","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.envpol.2018.02.024_bib48","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/j.jhazmat.2016.05.002","article-title":"Variable effects of oxytetracycline on antibiotic resistance gene abundance and the bacterial community during aerobic composting of cow manure","volume":"315","author":"Qian","year":"2016","journal-title":"J.\u00a0Haz. Mater."},{"key":"10.1016\/j.envpol.2018.02.024_bib49","doi-asserted-by":"crossref","first-page":"1047","DOI":"10.1016\/S1001-0742(11)60890-5","article-title":"Fate of tetracyclines in swine manure of three selected swine farms in China","volume":"24","author":"Qiao","year":"2012","journal-title":"J.\u00a0Environ. Sci."},{"key":"10.1016\/j.envpol.2018.02.024_bib50","doi-asserted-by":"crossref","first-page":"752","DOI":"10.1002\/jps.2600520809","article-title":"Some observations on the kinetics of the C-4 epimerization of tetraycline","volume":"53","author":"Remmers","year":"1963","journal-title":"J.\u00a0Pharm. Sci."},{"key":"10.1016\/j.envpol.2018.02.024_bib51","doi-asserted-by":"crossref","first-page":"3165","DOI":"10.3168\/jds.2008-1799","article-title":"Seasonal incidence of lameness and risk factors associated with thin soles, white line disease, ulcers, and sole punctures in dairy cattle","volume":"92","author":"Sanders","year":"2009","journal-title":"J.\u00a0Dairy Sci."},{"key":"10.1016\/j.envpol.2018.02.024_bib52","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1080\/03601230701734824","article-title":"Fate in soil of 14C-sulfadiazine residues contained in the manure of young pigs treated with a veterinary antibiotic","volume":"43","author":"Schmidt","year":"2007","journal-title":"J.\u00a0Environ. Sci. Health, Part B"},{"key":"10.1016\/j.envpol.2018.02.024_bib53","doi-asserted-by":"crossref","first-page":"399","DOI":"10.3389\/fmicb.2012.00399","article-title":"Heavy metal driven co-selection of antibiotic resistance in soil and water bodies impacted by agriculture and aquaculture","volume":"3","author":"Seiler","year":"2012","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.envpol.2018.02.024_bib54","doi-asserted-by":"crossref","first-page":"2433","DOI":"10.1080\/09593330.2013.772644","article-title":"Degradation of tetracycline and sulfadiazine during continuous thermophillic composting of pig maure and sawdust","volume":"34","author":"Selvam","year":"2013","journal-title":"Environ. Technol."},{"key":"10.1016\/j.envpol.2018.02.024_bib55","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1016\/j.anifeedsci.2011.04.033","article-title":"Effect of antibiotics on methane arising from anaerobic digestion of pig manure","volume":"166\u2013167","author":"Shi","year":"2011","journal-title":"Anim. Feed Sci. Technol."},{"key":"10.1016\/j.envpol.2018.02.024_bib56","doi-asserted-by":"crossref","first-page":"1515","DOI":"10.1016\/j.chemosphere.2004.09.020","article-title":"Chemical stability of chlortetracycline and chlortetracycline degradation products and epimers in soil interstitial water","volume":"57","author":"Soeborg","year":"2004","journal-title":"Chemosphere"},{"key":"10.1016\/j.envpol.2018.02.024_bib57","doi-asserted-by":"crossref","first-page":"1159","DOI":"10.1002\/jps.2600660829","article-title":"Rate and proposed mechanism of anhydrotetracycline epimerization in acid solution","volume":"66","author":"Sokoloski","year":"1977","journal-title":"J.\u00a0Pharm. Sci."},{"key":"10.1016\/j.envpol.2018.02.024_bib58","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1016\/j.biortech.2015.06.081","article-title":"Elimination patterns of worldwide used sulfonamides and tetracyclines during anaerobic fermentation","volume":"193","author":"Spielmeyer","year":"2015","journal-title":"Bioresour. Technol."},{"key":"10.1016\/j.envpol.2018.02.024_bib59","doi-asserted-by":"crossref","first-page":"4740","DOI":"10.1016\/j.watres.2009.08.005","article-title":"Effect of antimicrobial compounds tylosin and chlortetracycline during batch anaerobic swine manure digestion","volume":"43","author":"Stone","year":"2009","journal-title":"Water Res."},{"key":"10.1016\/j.envpol.2018.02.024_bib60","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/j.envres.2008.12.007","article-title":"Metabolism and excretion kinetics of 14C-labeled and non-labeled difloxacin in pigs after oral administration, and antimicrobial activity of manure containing difloxacin and its metabolites","volume":"109","author":"Sukul","year":"2009","journal-title":"Environ. Res."},{"key":"10.1016\/j.envpol.2018.02.024_bib61","series-title":"Waste Handling Facilities and Manure Management on U.S. Dairy Operations","author":"USDA","year":"1996"},{"key":"10.1016\/j.envpol.2018.02.024_bib62","series-title":"Dairy 2014: Dairy Cattle Managment Practices in the United States, 2014","author":"USDA","year":"2016"},{"key":"10.1016\/j.envpol.2018.02.024_bib63","series-title":"AgStar Database of Livestock Digesters","author":"USEPA","year":"2016"},{"key":"10.1016\/j.envpol.2018.02.024_bib64","series-title":"Milk Monitoring with Antimicrobial Drug Screening Tests","author":"USFDA","year":"1996"},{"key":"10.1016\/j.envpol.2018.02.024_bib65","series-title":"2015 Summary Report on Antimicrobials Sold or Distributed for Use in Food-producing Animals","author":"USFDA","year":"2016"},{"key":"10.1016\/j.envpol.2018.02.024_bib66","series-title":"Modernizing Environmental Analysis: Mass Spectrometry as a Tool for Investigating and Answering Salient Environmental Questions","first-page":"342","author":"Wallace","year":"2016"},{"key":"10.1016\/j.envpol.2018.02.024_bib67","doi-asserted-by":"crossref","first-page":"471","DOI":"10.2134\/jeq2015.05.0246","article-title":"Enhancing extraction and detection of veterinary antibiotics in solid and liquid fractions of manure","volume":"45","author":"Wallace","year":"2016","journal-title":"J.\u00a0Environ. Qual."},{"key":"10.1016\/j.envpol.2018.02.024_bib68","doi-asserted-by":"crossref","first-page":"1683","DOI":"10.1021\/jf072927p","article-title":"Laboratory study of oxytetracycline degradation kinetics in animal manure and soil","volume":"56","author":"Wang","year":"2008","journal-title":"J.\u00a0Agric. Food Chem."},{"key":"10.1016\/j.envpol.2018.02.024_bib69","doi-asserted-by":"crossref","first-page":"5924","DOI":"10.1016\/j.biortech.2011.03.007","article-title":"The behavior of tetracyclines and their degradation products during swine manure composting","volume":"102","author":"Wu","year":"2011","journal-title":"Bioresour. Technol."},{"key":"10.1016\/j.envpol.2018.02.024_bib70","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/j.chroma.2005.08.027","article-title":"Simultaneous extraction and analysis of 11 tetracycline and sulfonamide antibiotics in influent and effluent domestic wastewater by solid-phase extraction and liquid chromatography-electrospray ionization tandem mass spectrometry","volume":"1097","author":"Yang","year":"2005","journal-title":"J.\u00a0Chromatogr. A"},{"key":"10.1016\/j.envpol.2018.02.024_bib71","doi-asserted-by":"crossref","first-page":"1069","DOI":"10.1016\/j.scitotenv.2009.11.014","article-title":"Residues of veterinary antibiotics in manures from feedlot livestock in eight provinces of China","volume":"408","author":"Zhao","year":"2010","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.envpol.2018.02.024_bib72","doi-asserted-by":"crossref","first-page":"4758","DOI":"10.1016\/j.watres.2011.06.014","article-title":"Net energy production associated with pathogen inactivation during mesophilic and thermophilic anaerobic digestion of sewage sludge","volume":"45","author":"Ziemba","year":"2011","journal-title":"Water Res."},{"key":"10.1016\/j.envpol.2018.02.024_bib73","doi-asserted-by":"crossref","first-page":"191","DOI":"10.3168\/jds.S0022-0302(04)73158-6","article-title":"Management practices and reported antimicrobial usage on conventional and organic dairy farms","volume":"87","author":"Zwald","year":"2004","journal-title":"J.\u00a0Dairy Sci."}],"container-title":["Environmental Pollution"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0269749117352260?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0269749117352260?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,2]],"date-time":"2025-10-02T20:41:33Z","timestamp":1759437693000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0269749117352260"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,5]]},"references-count":73,"alternative-id":["S0269749117352260"],"URL":"https:\/\/doi.org\/10.1016\/j.envpol.2018.02.024","relation":{},"ISSN":["0269-7491"],"issn-type":[{"value":"0269-7491","type":"print"}],"subject":[],"published":{"date-parts":[[2018,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Occurrence and transformation of veterinary antibiotics and antibiotic resistance genes in dairy manure treated by advanced anaerobic digestion and conventional treatment methods","name":"articletitle","label":"Article Title"},{"value":"Environmental Pollution","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.envpol.2018.02.024","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}