{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,4]],"date-time":"2025-11-04T23:29:37Z","timestamp":1762298977190,"version":"build-2065373602"},"reference-count":43,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2019,6,1]],"date-time":"2019-06-01T00:00:00Z","timestamp":1559347200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,6,1]],"date-time":"2019-06-01T00:00:00Z","timestamp":1559347200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100009210","name":"Taiwan Food and Drug Administration","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100009210","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100008903","name":"Ministry of Health and Welfare","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100008903","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Department of Health"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Environmental Pollution"],"published-print":{"date-parts":[[2019,6]]},"DOI":"10.1016\/j.envpol.2019.03.040","type":"journal-article","created":{"date-parts":[[2019,3,14]],"date-time":"2019-03-14T03:31:11Z","timestamp":1552534271000},"page":"728-734","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":14,"special_numbering":"C","title":["Dietary exposure and risk assessment of exposure to hexabromocyclododecanes in a Taiwan population"],"prefix":"10.1016","volume":"249","author":[{"given":"Ching-Chang","family":"Lee","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wei-Hsiang","family":"Chang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4285-420X","authenticated-orcid":false,"given":"Hsiu-Ling","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.envpol.2019.03.040_bib1","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1016\/j.envpol.2016.02.026","article-title":"Hexabromocyclododecane (HBCD) in the Korean food basket and estimation of dietary exposure","volume":"213","author":"Barghi","year":"2016","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.envpol.2019.03.040_bib2","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1016\/j.taap.2008.04.013","article-title":"Subacute effects of hexabromocyclododecane (HBCD) on hepatic gene expression profiles in rats","volume":"231","author":"Canton","year":"2008","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"10.1016\/j.envpol.2019.03.040_bib3","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1016\/j.envpol.2018.01.040","article-title":"An overview of hexabromocyclododecane (HBCDs) in environmental media with focus on their potential risk and management in China","volume":"236","author":"Cao","year":"2018","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.envpol.2019.03.040_bib4","doi-asserted-by":"crossref","first-page":"4387","DOI":"10.1016\/j.scitotenv.2008.09.057","article-title":"Brominated flame retardants in Belgian home-produced eggs: levels and contamination sources","volume":"407","author":"Covaci","year":"2009","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.envpol.2019.03.040_bib5","first-page":"498","article-title":"Levels of hexabromocyclododecane in human breast milk and the daily intake of newborns in a Shanghai hospital","volume":"45","author":"Ding","year":"2011","journal-title":"Zhonghua Yufang Yixue Zazhi"},{"key":"10.1016\/j.envpol.2019.03.040_bib6","doi-asserted-by":"crossref","first-page":"11040","DOI":"10.1021\/es302166p","article-title":"Diastereoisomer- and enantiomer-specific accumulation, depuration, and bioisomerization of hexabromocyclododecanes in zebrafish (Danio rerio)","volume":"46","author":"Du","year":"2012","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.envpol.2019.03.040_bib7","first-page":"2405","article-title":"EFSA panel on contaminants in the food chain (CONTAM)","volume":"9","author":"EFSA","year":"2011","journal-title":"EFSA J."},{"key":"10.1016\/j.envpol.2019.03.040_bib8","doi-asserted-by":"crossref","first-page":"2462","DOI":"10.1021\/jf405007x","article-title":"Dietary exposure assessment of Spanish citizens to hexabromocyclododecane through the diet","volume":"62","author":"Eljarrat","year":"2014","journal-title":"J.\u00a0Agric. Food Chem."},{"key":"10.1016\/j.envpol.2019.03.040_bib9","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1016\/j.chemosphere.2011.04.048","article-title":"Dietary intake of hexabromocyclododecane diastereoisomers (alpha-, beta-, and gamma-HBCD) in the Belgian adult population","volume":"84","author":"Goscinny","year":"2011","journal-title":"Chemosphere"},{"key":"10.1016\/j.envpol.2019.03.040_bib10","doi-asserted-by":"crossref","first-page":"9077","DOI":"10.1021\/es902185u","article-title":"Current-use brominated flame retardants in water, sediment, and fish from English lakes","volume":"43","author":"Harrad","year":"2009","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.envpol.2019.03.040_bib11","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/j.envpol.2013.04.016","article-title":"Diasteroisomer and enantiomer-specific profiles of hexabromocyclododecane and tetrabromobisphenol A in an aquatic environment in a highly industrialized area, South China: vertical profile, phase partition, and bioaccumulation","volume":"179","author":"He","year":"2013","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.envpol.2019.03.040_bib12","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.aquatox.2017.04.010","article-title":"Toxicity and bioaccumulation of three hexabromocyclododecane diastereoisomers in the marine copepod Tigriopus japonicas","volume":"188","author":"Hong","year":"2017","journal-title":"Aquat. Toxicol."},{"key":"10.1016\/j.envpol.2019.03.040_bib13","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.neulet.2011.01.062","article-title":"Brain-derived neurotrophic factor (BDNF) ameliorates the suppression of thyroid hormone-induced granule cell neurite extension by hexabromocyclododecane (HBCD)","volume":"493","author":"Ibhazehiebo","year":"2011","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.envpol.2019.03.040_bib14","doi-asserted-by":"crossref","first-page":"1987","DOI":"10.1021\/es0484909","article-title":"Hexabromocyclododecane in marine species from the western Scheldt Estuary:\u2009 diastereoisomer- and enantiomer-specific accumulation","volume":"39","author":"Jan\u00e1k","year":"2005","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.envpol.2019.03.040_bib15","doi-asserted-by":"crossref","first-page":"1471","DOI":"10.1016\/j.scitotenv.2013.10.038","article-title":"Hexabromocyclododecanes in crucian carp and sediment from the major rivers in Korea","volume":"470\u2013471","author":"Jeong","year":"2014","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.envpol.2019.03.040_bib16","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1016\/j.envpol.2017.04.093","article-title":"Matrix-specific distribution and diastereomeric profiles of hexabromocyclododecane (HBCD) in a multimedia environment: air, soil, sludge, sediment, and fish","volume":"226","author":"Jo","year":"2017","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.envpol.2019.03.040_bib17","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1016\/j.envint.2014.10.020","article-title":"Human dietary intake of organohalogen contaminants at e-waste recycling sites in Eastern China","volume":"74","author":"Labunska","year":"2015","journal-title":"Environ. Int."},{"key":"10.1016\/j.envpol.2019.03.040_bib18","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/j.chemosphere.2008.02.066","article-title":"Levels and trends of HBCD and BDEs in the European and Asian environments, with some information for other BFRs","volume":"73","author":"Law","year":"2008","journal-title":"Chemosphere"},{"key":"10.1016\/j.envpol.2019.03.040_bib19","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/j.toxlet.2008.12.002","article-title":"Effects of the brominated flame retardant hexabromocyclododecane (HBCD) on dopamine-dependent behavior and brainstem auditory evoked potentials in a one-generation reproduction study in Wistar rats","volume":"185","author":"Lilienthal","year":"2009","journal-title":"Toxicol. Lett."},{"key":"10.1016\/j.envpol.2019.03.040_bib20","doi-asserted-by":"crossref","first-page":"1424","DOI":"10.1002\/etc.1826","article-title":"Hexabromocyclododecane in consumer fish from South China: implications for human exposure via dietary intake","volume":"31","author":"Meng","year":"2012","journal-title":"Environ. Toxicol. Chem."},{"key":"10.1016\/j.envpol.2019.03.040_bib21","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/j.toxlet.2016.01.002","article-title":"Hexabromocyclododecane (HBCD) induced changes in the liver proteome of eu- and hypothyroid female rats","volume":"245","author":"Miller","year":"2016","journal-title":"Toxicol. Lett. (Amst.)"},{"key":"10.1016\/j.envpol.2019.03.040_bib22","doi-asserted-by":"crossref","first-page":"5497","DOI":"10.1021\/es049640i","article-title":"Distribution and fate of HBCD and TBBPA brominated flame retardants in north sea estuaries and aquatic food webs","volume":"38","author":"Morris","year":"2004","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.envpol.2019.03.040_bib23","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1016\/j.chemosphere.2010.08.015","article-title":"Hexabromocyclododecane determination in seafood samples collected from Japanese coastal areas","volume":"81","author":"Nakagawa","year":"2010","journal-title":"Chemosphere"},{"author":"NHRI","key":"10.1016\/j.envpol.2019.03.040_bib24"},{"key":"10.1016\/j.envpol.2019.03.040_bib25","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1016\/j.scitotenv.2014.01.104","article-title":"Food risk assessment for perfluoroalkyl acids and brominated flame retardants in the French population: results from the second French total diet study","volume":"491\u2013492","author":"Rivi\u00e8re","year":"2014","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.envpol.2019.03.040_bib26","doi-asserted-by":"crossref","first-page":"1707","DOI":"10.1289\/ehp.0900869","article-title":"Exposure to hexabromocyclododecanes (HBCDs) via dust ingestion, but not diet, correlates with concentrations in human serum: preliminary results","volume":"117","author":"Roosens","year":"2009","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.envpol.2019.03.040_bib27","doi-asserted-by":"crossref","first-page":"976","DOI":"10.1016\/j.envint.2008.02.009","article-title":"Brominated flame retardants and polychlorinated biphenyls in fish from the river Scheldt, Belgium","volume":"34","author":"Roosens","year":"2008","journal-title":"Environ. Int."},{"key":"10.1016\/j.envpol.2019.03.040_bib28","doi-asserted-by":"crossref","first-page":"1904","DOI":"10.1016\/j.chemosphere.2006.07.077","article-title":"Disruption of thyroid hormone-mediated Xenopus laevis tadpole tail tip regression by hexabromocyclododecane (HBCD) and 2,2',3,3',4,4',5,5',6-nona brominated diphenyl ether (BDE206)","volume":"65","author":"Schriks","year":"2006","journal-title":"Chemosphere"},{"key":"10.1016\/j.envpol.2019.03.040_bib29","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.envint.2012.01.001","article-title":"Tissue-specific accumulation of polybrominated diphenyl ethers (PBDEs) including Deca-BDE and hexabromocyclododecanes (HBCDs) in harbor seals from the northwest Atlantic","volume":"44","author":"Shaw","year":"2012","journal-title":"Environ. Int."},{"key":"10.1016\/j.envpol.2019.03.040_bib30","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1016\/j.envpol.2017.06.093","article-title":"Dietary exposure assessment of Chinese population to tetrabromobisphenol-A, hexabromocyclododecane and decabrominated diphenyl ether: results of the 5th Chinese Total Diet Study","volume":"229","author":"Shi","year":"2017","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.envpol.2019.03.040_bib31","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1016\/j.scitotenv.2017.04.237","article-title":"A national survey of tetrabromobisphenol-A, hexabromocyclododecane and decabrominated diphenyl ether in human milk from China: occurrence and exposure assessment","volume":"599-600","author":"Shi","year":"2017","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.envpol.2019.03.040_bib32","doi-asserted-by":"crossref","first-page":"4314","DOI":"10.1021\/es8035626","article-title":"Dietary exposure assessment of Chinese adults and nursing infants to tetrabromobisphenol-A and hexabromocyclododecanes: occurrence measurements in foods and human milk","volume":"43","author":"Shi","year":"2009","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.envpol.2019.03.040_bib33","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1016\/j.marpolbul.2017.11.040","article-title":"Hexabromocyclododecanes (HBCDs) in fish: evidence of recent HBCD input into the coastal environment","volume":"126","author":"Sun","year":"2018","journal-title":"Mar. Pollut. Bull."},{"key":"10.1016\/j.envpol.2019.03.040_bib34","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1093\/toxsci\/kfq183","article-title":"Toxicokinetics of the flame retardant hexabromocyclododecane gamma: effect of dose, timing, route, repeated exposure, and metabolism","volume":"117","author":"Szabo","year":"2010","journal-title":"Toxicol. Sci."},{"key":"10.1016\/j.envpol.2019.03.040_bib35","doi-asserted-by":"crossref","first-page":"12011","DOI":"10.1007\/s11356-015-4463-1","article-title":"Bioaccumulative characteristics of tetrabromobisphenol A and hexabromocyclododecanes in multi-tissues of prey and predator fish from an e-waste site, South China","volume":"22","author":"Tang","year":"2015","journal-title":"Environ. Sci. Pollut. Res. Int."},{"key":"10.1016\/j.envpol.2019.03.040_bib36","first-page":"225","article-title":"Design and sample characteristics of the 2005-2008 nutrition and health survey in Taiwan. Asia pacific JClin","volume":"20","author":"Tu","year":"2011","journal-title":"Nutrients"},{"key":"10.1016\/j.envpol.2019.03.040_bib37","first-page":"507","article-title":"Nutrition and health survey of Taiwan elementary school children 2001-2002: Research design, methods and scope. Asia pacific JClin","volume":"16","author":"Tu","year":"2007","journal-title":"Nutrients"},{"year":"2013","series-title":"United Nations Environment Annual Report","author":"UNEP","key":"10.1016\/j.envpol.2019.03.040_bib38"},{"key":"10.1016\/j.envpol.2019.03.040_bib39","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1016\/j.scitotenv.2018.03.262","article-title":"The occurrence and distribution of hexabromocyclododecanes in freshwater systems, focusing on tissue-specific bioaccumulation in crucian carp","volume":"635","author":"Wang","year":"2018","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.envpol.2019.03.040_bib40","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1016\/j.scitotenv.2016.03.166","article-title":"Occurrence of Hexabromocyclododecane in soil and road dust from mixed-land-use areas of Shanghai, China, and its implications for human exposure","volume":"559","author":"Wu","year":"2016","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.envpol.2019.03.040_bib41","first-page":"41","article-title":"Food sources of weight, calories, and three macro-nutrients - NAHSIT 1993-1996","volume":"24","author":"Wu","year":"1999","journal-title":"Nutr. Sci. J"},{"key":"10.1016\/j.envpol.2019.03.040_bib42","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1007\/s00244-014-0040-8","article-title":"Species-specific bioaccumulation of halogenated organic pollutants and their metabolites in fish serum from an e-waste site, South China","volume":"67","author":"Zeng","year":"2014","journal-title":"Arch. Environ. Contam. Toxicol."},{"key":"10.1016\/j.envpol.2019.03.040_bib43","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/j.envpol.2013.05.050","article-title":"Hexabromocyclododecane in alpine fish from the Tibetan Plateau, China","volume":"181","author":"Zhu","year":"2013","journal-title":"Environ. Pollut."}],"container-title":["Environmental Pollution"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S026974911835228X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S026974911835228X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,2]],"date-time":"2025-10-02T21:07:05Z","timestamp":1759439225000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S026974911835228X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,6]]},"references-count":43,"alternative-id":["S026974911835228X"],"URL":"https:\/\/doi.org\/10.1016\/j.envpol.2019.03.040","relation":{},"ISSN":["0269-7491"],"issn-type":[{"type":"print","value":"0269-7491"}],"subject":[],"published":{"date-parts":[[2019,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Dietary exposure and risk assessment of exposure to hexabromocyclododecanes in a Taiwan population","name":"articletitle","label":"Article Title"},{"value":"Environmental Pollution","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.envpol.2019.03.040","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}