{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T17:08:15Z","timestamp":1789146495705,"version":"build-2803163510"},"reference-count":127,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2019,9,1]],"date-time":"2019-09-01T00:00:00Z","timestamp":1567296000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,9,1]],"date-time":"2019-09-01T00:00:00Z","timestamp":1567296000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100003593","name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Environmental Pollution"],"published-print":{"date-parts":[[2019,9]]},"DOI":"10.1016\/j.envpol.2019.06.100","type":"journal-article","created":{"date-parts":[[2019,6,28]],"date-time":"2019-06-28T08:56:59Z","timestamp":1561712219000},"page":"1841-1853","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":131,"special_numbering":"PB","title":["The zebrafish embryotoxicity test (ZET) for nanotoxicity assessment: from morphological to molecular approach"],"prefix":"10.1016","volume":"252","author":[{"given":"Aryelle Canedo","family":"Pereira","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T\u00e2nia","family":"Gomes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M\u00f4nica Rodrigues","family":"Ferreira Machado","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thiago Lopes","family":"Rocha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.envpol.2019.06.100_bib2","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/j.aquatox.2015.07.003","article-title":"An in\u00a0vivo evaluation of acute toxicity of Cobalt ferrite (CoFe2O4) nanoparticles in larval-embryo Zebrafish (Danio rerio)","volume":"166","author":"Ahamad","year":"2015","journal-title":"Aquat. Toxicol."},{"key":"10.1016\/j.envpol.2019.06.100_bib3","doi-asserted-by":"crossref","first-page":"43","DOI":"10.3109\/17435390.2010.489207","article-title":"Comparison of the toxicity of silver, gold and platinum nanoparticles in developing zebrafish embryos","volume":"5","author":"Asharani","year":"2011","journal-title":"Nanotoxicology"},{"key":"10.1016\/j.envpol.2019.06.100_bib4","doi-asserted-by":"crossref","first-page":"3603","DOI":"10.1166\/jnn.2008.432","article-title":"Impact of multi-walled carbon nanotubes on aquatic species","volume":"8","author":"Asharani","year":"2008","journal-title":"J.\u00a0Nanosci. Nanotechnol."},{"key":"10.1016\/j.envpol.2019.06.100_bib5","doi-asserted-by":"crossref","first-page":"255102","DOI":"10.1088\/0957-4484\/19\/25\/255102","article-title":"Toxicity of silver nanoparticles in zebrafish models","volume":"19","author":"Asharani","year":"2008","journal-title":"Nanotechnology"},{"key":"10.1016\/j.envpol.2019.06.100_bib6","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.watres.2017.02.049","article-title":"Embryotoxic and genotoxic effects of sewage effluents in zebrafish embryo using multiple endpoint testing","volume":"115","author":"Babi\u0107","year":"2017","journal-title":"Water Res."},{"key":"10.1016\/j.envpol.2019.06.100_bib8","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1016\/bs.ctdb.2016.10.007","article-title":"Zebrafish in toxicology and environmental health","volume":"124","author":"Bambino","year":"2017","journal-title":"Curr. Top. Dev. Biol."},{"key":"10.1016\/j.envpol.2019.06.100_bib9","doi-asserted-by":"crossref","first-page":"1897","DOI":"10.1002\/smll.200801716","article-title":"Toxicity assessments of multisized gold and silver nanoparticles in zebrafish embryos","volume":"16","author":"Bar-llan","year":"2009","journal-title":"Small"},{"key":"10.1016\/j.envpol.2019.06.100_bib10","doi-asserted-by":"crossref","first-page":"670","DOI":"10.3109\/17435390.2011.604438","article-title":"Titanium dioxide nanoparticles produce phototoxicity in the developing zebrafish","volume":"6","author":"Bar-llan","year":"2012","journal-title":"Nanotoxicology"},{"key":"10.1016\/j.envpol.2019.06.100_bib11","first-page":"22","article-title":"Toxicity of PVA-stabilized silver nanoparticles to algae and microcrustaceans","volume":"3","author":"Becaro","year":"2015","journal-title":"Environ. Nanotechnol. Monit. Manag."},{"key":"10.1016\/j.envpol.2019.06.100_bib12","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1016\/j.reprotox.2015.06.050","article-title":"From cutting edge to guideline: a first step in harmonization of the zebrafish embryotoxicity test (ZET) by describing the most optimal test conditions and morphology scoring system","volume":"56","author":"Beekhuizen","year":"2015","journal-title":"Reprod. Toxicol."},{"key":"10.1016\/j.envpol.2019.06.100_bib13","doi-asserted-by":"crossref","first-page":"1147","DOI":"10.1016\/j.drudis.2012.06.014","article-title":"Silica-based nanoparticles for biomedical applications","volume":"17","author":"Bitar","year":"2012","journal-title":"Drug Discov. Today"},{"key":"10.1016\/j.envpol.2019.06.100_bib14","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.impact.2018.08.006","article-title":"Effects of silver nanoparticles in early life-stage zebrafish are associated with particle dissolution and the toxicity of soluble silver","volume":"12","author":"Boley","year":"2018","journal-title":"NanoImpact"},{"key":"10.1016\/j.envpol.2019.06.100_bib16","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1007\/s40572-014-0029-5","article-title":"Zebrafish: a marvel of high-throughput biology for 21st century toxicology","volume":"1","author":"Bugel","year":"2014","journal-title":"Curr. Environ. Health. Rep."},{"key":"10.1016\/j.envpol.2019.06.100_bib201","doi-asserted-by":"crossref","first-page":"496","DOI":"10.1016\/j.yrtph.2014.05.018","article-title":"OECD validation study to assess intra- and inter-laboratory reproducibility of the Zebrafish embryo toxicity test for acute aquatic toxicity testing","volume":"69","author":"Busquet","year":"2014","journal-title":"Regul. Toxicol. Pharmacol."},{"key":"10.1016\/j.envpol.2019.06.100_bib17","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12302-018-0132-6","article-title":"Nanoparticles in the environment: where do we come from, where do we go to?","volume":"30","author":"Bundschuh","year":"2018","journal-title":"Environ. Sci. Eur."},{"key":"10.1016\/j.envpol.2019.06.100_bib21","doi-asserted-by":"crossref","first-page":"1998","DOI":"10.1002\/etc.4145","article-title":"Nanoecotoxicity assessment of graphene oxide and its relationship with humic acid","volume":"37","author":"Castro","year":"2018","journal-title":"Environ. Toxicol. Chem."},{"key":"10.1016\/j.envpol.2019.06.100_bib22","first-page":"14","article-title":"Zebrafish: a complete animal model to enumerate the nanoparticle toxicity","author":"Chakraborty","year":"2016","journal-title":"NanoBiotechnology"},{"key":"10.1016\/j.envpol.2019.06.100_bib23","doi-asserted-by":"crossref","first-page":"570","DOI":"10.1016\/j.chemosphere.2018.04.075","article-title":"Uptake of BDE-209 on zebrafish embryos as affected by SiO2 nanoparticles","volume":"205","author":"Chao","year":"2018","journal-title":"Chemosphere"},{"key":"10.1016\/j.envpol.2019.06.100_bib24","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1016\/j.chemosphere.2017.03.075","article-title":"Teratogenic responses of zebrafish embryos to decabromodiphenyl ether (BDE-209) in the presence of nano-SiO2 particles","volume":"178","author":"Chao","year":"2017","journal-title":"Chemosphere"},{"key":"10.1016\/j.envpol.2019.06.100_bib26","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1016\/j.chemosphere.2017.05.173","article-title":"Intensive epidermal adsorption and specific venous deposition of carboxyl quantum dots in zebrafish early-life stages","volume":"184","author":"Chen","year":"2017","journal-title":"Chemosphere"},{"key":"10.1016\/j.envpol.2019.06.100_bib27","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1016\/j.jhazmat.2013.12.030","article-title":"Zinc oxide nanoparticles alter hatching and larval locomotor activity in zebrafish (Danio rerio)","volume":"277","author":"Chen","year":"2014","journal-title":"J.\u00a0Hazard Mater."},{"key":"10.1016\/j.envpol.2019.06.100_bib28","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1016\/j.marpolbul.2011.04.017","article-title":"Behavioral effects of titanium dioxide nanoparticles on larval zebrafish (Danio rerio)","volume":"63","author":"Chen","year":"2011","journal-title":"Mar. Pollut. Bull."},{"key":"10.1016\/j.envpol.2019.06.100_bib30","doi-asserted-by":"crossref","first-page":"708","DOI":"10.1897\/06-272R.1","article-title":"Effect of carbon nanotubes on development zebrafish (Danio rerio) embryos","volume":"26","author":"Cheng","year":"2007","journal-title":"Environ. Toxicol. Chem."},{"key":"10.1016\/j.envpol.2019.06.100_bib31","article-title":"Developmental toxicity of zinc oxide nanoparticles to zebrafish (Danio rerio): a transcriptomic analysis","volume":"11","author":"Choi","year":"2016","journal-title":"PLoS One"},{"key":"10.1016\/j.envpol.2019.06.100_bib32","first-page":"45","article-title":"Perspectivas do uso do teste com embri\u00f5es de zebrafish no \u00e2mbito da nanotoxicologia","volume":"4","author":"Clemente","year":"2017","journal-title":"Resbcal"},{"key":"10.1016\/j.envpol.2019.06.100_bib202","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1016\/j.taap.2018.03.031","article-title":"Toxicological assessment of PEGylated single-walled carbon nanotubes in early developing Zebrafish","volume":"15","author":"Cordeiro","year":"2018","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"10.1016\/j.envpol.2019.06.100_bib33","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1016\/j.aquatox.2016.06.005","article-title":"Silver nanoparticles inhibited erythrogenesis during zebrafish embryogenesis","volume":"177","author":"Cui","year":"2016","journal-title":"Aquat. Toxicol."},{"key":"10.1016\/j.envpol.2019.06.100_bib34","doi-asserted-by":"crossref","first-page":"999","DOI":"10.1016\/j.envpol.2018.06.042","article-title":"The interactions of fullerene C60 and Benzo(\u03b1)pyrene influence their bioavailability and toxicity to zebrafish embryos","volume":"241","author":"Della Torre","year":"2018","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.envpol.2019.06.100_bib35","doi-asserted-by":"crossref","first-page":"594","DOI":"10.1590\/S1415-47572009005000062","article-title":"Molecular cloning and expression analysis of a zebrafish novel zinc finger protein gene rnf141","volume":"32","author":"Deng","year":"2009","journal-title":"Genet. Mol. Biol."},{"key":"10.1016\/j.envpol.2019.06.100_bib36","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1016\/S0959-437X(00)00074-5","article-title":"Zebrafish: a model system for the study of human disease","volume":"10","author":"Dooley","year":"2000","journal-title":"Curr. Opin. Genet. Dev."},{"key":"10.1016\/j.envpol.2019.06.100_bib37","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/j.jes.2016.01.018","article-title":"Effects of ZnO nanoparticles on perfluorooctane sulfonate induced thyroid-disrupting on zebrafish larvae","volume":"47","author":"Du","year":"2016","journal-title":"J.\u00a0Environ. Sci. (China)"},{"key":"10.1016\/j.envpol.2019.06.100_bib38","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1016\/j.chemosphere.2017.05.138","article-title":"Silica nanoparticles inhibit macrophage activity and angiogenesis via VEGFR2-mediated MAPK signaling pathway in zebrafish embryos","volume":"183","author":"Duan","year":"2017","journal-title":"Chemosphere"},{"key":"10.1016\/j.envpol.2019.06.100_bib39","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1016\/j.etap.2016.05.004","article-title":"Combined toxicity of silica nanoparticles and methylmercury on cardiovascular system in zebrafish (Danio rerio) embryos","volume":"44","author":"Duan","year":"2016","journal-title":"Environ. Toxicol. Pharmacol."},{"key":"10.1016\/j.envpol.2019.06.100_bib41","doi-asserted-by":"crossref","first-page":"478","DOI":"10.1016\/j.addr.2009.03.008","article-title":"Zebrafish as a correlative and predictive model for assessing biomaterial nanotoxicity","volume":"61","author":"Fako","year":"2009","journal-title":"Adv. Drug Deliv. Rev."},{"key":"10.1016\/j.envpol.2019.06.100_bib42","doi-asserted-by":"crossref","first-page":"897","DOI":"10.1016\/j.jhazmat.2014.10.039","article-title":"Effect of titanium dioxide nanoparticles on the bioavailability,metabolism, and toxicity of pentachlorophenol in zebrafish larvae","volume":"283","author":"Fang","year":"2014","journal-title":"J.\u00a0Hazard Mater."},{"key":"10.1016\/j.envpol.2019.06.100_bib43","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1016\/j.scitotenv.2013.09.055","article-title":"Oxidative stress effects of titanium dioxide nanoparticle aggregates in zebrafish embryos","volume":"470\u2013471","author":"Faria","year":"2014","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.envpol.2019.06.100_bib44","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1016\/j.aquatox.2010.02.019","article-title":"Assessment of uptake and toxicity of fluorescent silica nanoparticles in zebrafish (Danio rerio) early life stages","volume":"100","author":"Fent","year":"2010","journal-title":"Aquat. Toxicol."},{"key":"10.1016\/j.envpol.2019.06.100_bib46","doi-asserted-by":"crossref","first-page":"554","DOI":"10.1002\/jat.3224","article-title":"Acute and sub-lethal exposure to copper oxide nanoparticles causes oxidative stress and teratogenicity in zebrafish embryos","volume":"36","author":"Ganesan","year":"2015","journal-title":"J.\u00a0Appl. Toxicol."},{"key":"10.1016\/j.envpol.2019.06.100_bib47","doi-asserted-by":"crossref","first-page":"2113","DOI":"10.1016\/j.materresbull.2012.06.015","article-title":"Sun light mediated synthesis of gold nanoparticles as carrier for 6-mercaptopurine: preparation, characterization and toxicity studies in zebrafish embryo model","volume":"47","author":"Ganeshkumar","year":"2012","journal-title":"Mater. Res. Bull."},{"key":"10.1016\/j.envpol.2019.06.100_bib48","doi-asserted-by":"crossref","first-page":"1805","DOI":"10.1021\/nn102734s","article-title":"Use of a high-throughput screening approach coupled with in\u00a0vivo zebrafish embryo screening to develop hazard ranking for engineered nanomaterials","volume":"5","author":"George","year":"2011","journal-title":"ACS Nano"},{"key":"10.1016\/j.envpol.2019.06.100_bib50","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1016\/j.ecoenv.2015.08.009","article-title":"Toxic effects of magnesium oxide nanoparticles on early developmental and larval stages of zebrafish (Danio rerio)","volume":"122","author":"Ghobadian","year":"2015","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.envpol.2019.06.100_bib51","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1016\/j.nano.2013.09.010","article-title":"Non-mammalian vertebrate embryos as models in nanomedicine","volume":"10","author":"Giannaccini","year":"2014","journal-title":"Nanomedicine"},{"key":"10.1016\/j.envpol.2019.06.100_bib52","doi-asserted-by":"crossref","first-page":"1565","DOI":"10.1038\/s41598-018-19275-4","article-title":"Risks, release and concentrations of engineered nanomaterial in the environment","volume":"8","author":"Giese","year":"2018","journal-title":"Sci. Rep."},{"key":"10.1016\/j.envpol.2019.06.100_bib53","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1016\/j.msec.2015.07.017","article-title":"Studies on polymer-coated zinc oxide nanoparticles: UV-blocking efficacy and in\u00a0vivo toxicity","volume":"56","author":"Girigoswami","year":"2015","journal-title":"Mater. Sci. Eng. C. Mater. Biol. Appl."},{"key":"10.1016\/j.envpol.2019.06.100_bib54","doi-asserted-by":"crossref","first-page":"9216","DOI":"10.1021\/es9015553","article-title":"Modeled environmental concentrations of engineered nanomaterials for different regions","volume":"43","author":"Gottschalk","year":"2009","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.envpol.2019.06.100_bib55","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1016\/j.envpol.2013.06.003","article-title":"Environmental concentrations of engineered nanomaterials: review of modeling and analytical studies","volume":"181","author":"Gottschalk","year":"2013","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.envpol.2019.06.100_bib56","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1016\/j.aquatox.2013.01.010","article-title":"Chronic nanoparticulate silver exposure results in tissue accumulation and transcriptomic changes in zebrafish","volume":"130\u2013131","author":"Griffitt","year":"2013","journal-title":"Aquat. Toxicol."},{"key":"10.1016\/j.envpol.2019.06.100_bib57","first-page":"341","article-title":"Toxicity of graphene quantum dots in zebrafish embryo","volume":"28","author":"Guo","year":"2015","journal-title":"Biomed. Environ. Sci."},{"key":"10.1016\/j.envpol.2019.06.100_bib60","article-title":"Current perspectives of nanoparticles in medical and dental biomaterials","volume":"26","author":"Hamouda","year":"2012","journal-title":"J.\u00a0Biomed. Res."},{"key":"10.1016\/j.envpol.2019.06.100_bib61","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1002\/etc.706","article-title":"Ecotoxicity test methods for engineered nanomaterials: practical experiences and recommendations from the bench","volume":"31","author":"Handy","year":"2012","journal-title":"Environ. Toxicol. Chem."},{"key":"10.1016\/j.envpol.2019.06.100_bib62","doi-asserted-by":"crossref","first-page":"561","DOI":"10.3390\/nano8070561","article-title":"Zebrafish as a model to evaluate nanoparticle toxicity","volume":"8","author":"Haque","year":"2018","journal-title":"Nanomaterials (Basel)."},{"key":"10.1016\/j.envpol.2019.06.100_bib203","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1002\/ieam.39","article-title":"The nano cocktail: ecotoxicological effects of engineered nanoparticles in chemical mixtures","volume":"6","author":"Hartmann","year":"2010","journal-title":"Integr. Environ. Assess. Manag."},{"key":"10.1016\/j.envpol.2019.06.100_bib63","doi-asserted-by":"crossref","first-page":"4688","DOI":"10.1021\/nn200546k","article-title":"Systematic evaluation of nanomaterial toxicity: utility of standardized materials and rapid assays","volume":"5","author":"Harper","year":"2011","journal-title":"ACS Nano"},{"key":"10.1016\/j.envpol.2019.06.100_bib65","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1093\/toxsci\/kfi110","article-title":"Zebrafish as a model vertebrate for investigating chemical toxicity","volume":"86","author":"Hill","year":"2005","journal-title":"Toxicol. Sci."},{"key":"10.1016\/j.envpol.2019.06.100_bib66","doi-asserted-by":"crossref","first-page":"7996","DOI":"10.1021\/acs.est.8b01464","article-title":"Molecular toxicity of metal oxide nanoparticles in Danio rerio","volume":"52","author":"Hou","year":"2018","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.envpol.2019.06.100_bib67","doi-asserted-by":"crossref","first-page":"498","DOI":"10.1038\/nature12111","article-title":"A\u00a0sequ\u00eancia do genoma de refer\u00eancia em zebrafish e sua rela\u00e7\u00e3o com o genoma humano","volume":"496","author":"Howe","year":"2013","journal-title":"Nature"},{"key":"10.1016\/j.envpol.2019.06.100_bib68","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1016\/j.chemosphere.2017.01.063","article-title":"Effects of titanium dioxide nanoparticles exposure on parkinsonism in zebrafish larvae and PC12","volume":"173","author":"Hu","year":"2017","journal-title":"Chemosphere"},{"key":"10.1016\/j.envpol.2019.06.100_bib70","doi-asserted-by":"crossref","first-page":"2859","DOI":"10.1002\/etc.2758","article-title":"Particle-specific toxic effects of differently shaped zinc oxide nanoparticles to zebrafish embryos (Danio rerio)","volume":"33","author":"Hua","year":"2014","journal-title":"Environ. Toxicol. Chem."},{"key":"10.1016\/j.envpol.2019.06.100_bib73","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/j.taap.2011.03.014","article-title":"Comparison of the mouse Embryonic Stem cell Test, the rat Whole Embryo Culture and the Zebrafish Embryotoxicity Test as alternative methods for developmental toxicity testing of six 1,2,4 triazoles","volume":"253","author":"Jong","year":"2011","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"10.1016\/j.envpol.2019.06.100_bib74","doi-asserted-by":"crossref","first-page":"1697","DOI":"10.1289\/ehp.9209","article-title":"Distribution of nanoparticles in the see-through medaka (Oryzias latipes)","volume":"114","author":"Kashiwada","year":"2006","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.envpol.2019.06.100_bib75","doi-asserted-by":"crossref","first-page":"3184","DOI":"10.1074\/mcp.M114.038299","article-title":"Annotation of the zebrafish genome through an integrated transcriptomic and proteomic analysis","volume":"13","author":"Kelkar","year":"2014","journal-title":"Mol. Cell. Proteom."},{"key":"10.1016\/j.envpol.2019.06.100_bib76","article-title":"Dissipative flow of hybrid nanomaterial with entropy optimization","volume":"6","author":"Khan","year":"2019","journal-title":"Mater. Res. Express"},{"key":"10.1016\/j.envpol.2019.06.100_bib77","first-page":"1","article-title":"Nanoparticles: properties, applications and toxicities","author":"Khan","year":"2017","journal-title":"Arab. J. Chem"},{"key":"10.1016\/j.envpol.2019.06.100_bib204","doi-asserted-by":"crossref","first-page":"2014021","DOI":"10.5620\/eht.e2014021","article-title":"The role of chorion on toxicity of silver nanoparticles in the embryonic Zebrafish assay","volume":"29","author":"Kim","year":"2014","journal-title":"Environ. Health Toxicol."},{"key":"10.1016\/j.envpol.2019.06.100_bib78","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1002\/aja.1002030302","article-title":"Stages of embryonic development of the zebrafish","volume":"203","author":"Kimmel","year":"1995","journal-title":"Dev. Dynam."},{"key":"10.1016\/j.envpol.2019.06.100_bib80","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1539\/joh.17-0089-RA","article-title":"Review of toxicity studies of carbon nanotubes","volume":"59","author":"Kobayashi","year":"2017","journal-title":"J.\u00a0Occup. Health"},{"key":"10.1016\/j.envpol.2019.06.100_bib81","doi-asserted-by":"crossref","first-page":"2530","DOI":"10.1002\/etc.4212","article-title":"Development of cardiovascular and neurodevelopmental metrics as sublethal endpoints for the fish embryo toxicity test","volume":"37","author":"Krzykwa","year":"2018","journal-title":"Environ. Toxicol. Chem."},{"key":"10.1016\/j.envpol.2019.06.100_bib82","doi-asserted-by":"crossref","first-page":"1125","DOI":"10.1016\/j.envpol.2017.07.042","article-title":"Zinc oxide nanoparticle toxicity in embryonic zebrafish: mitigation with different natural organic matter","volume":"230","author":"Kteeba","year":"2017","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.envpol.2019.06.100_bib84","doi-asserted-by":"crossref","first-page":"325102","DOI":"10.1088\/0957-4484\/27\/32\/325102","article-title":"Effects of metal-bearing nanoparticles (Ag, Au, CdS, ZnO, SiO2) on developing zebrafish embryos","volume":"27","author":"Lacave","year":"2016","journal-title":"Nanotechnology"},{"key":"10.1016\/j.envpol.2019.06.100_bib85","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1016\/j.cbpc.2008.11.006","article-title":"Is the fish embryo toxicity test (FET) with the zebrafish (Danio rerio) a potential alternative for the fish acute toxicity test?","volume":"149","author":"Lammer","year":"2009","journal-title":"Comp. Biochem. Physiol. C Toxicol. Pharmacol."},{"key":"10.1016\/j.envpol.2019.06.100_bib86","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/j.watres.2017.12.017","article-title":"An integrated approach with the zebra fish model for biomonitoring of municipal wastewater effluent and receiving waters","volume":"131","author":"Li","year":"2018","journal-title":"Water Res."},{"key":"10.1016\/j.envpol.2019.06.100_bib87","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1016\/j.aquatox.2018.03.022","article-title":"Effect of titanium dioxide nanoparticles on the bioavailability and neurotoxicity of cypermethrin in zebrafish larvae","volume":"199","author":"Li","year":"2018","journal-title":"Aquat. Toxicol."},{"key":"10.1016\/j.envpol.2019.06.100_bib205","doi-asserted-by":"crossref","first-page":"4158","DOI":"10.1021\/es062629t","article-title":"Exposure of engineered nanoparticles to human lung epithelial cells: influence of chemical composition and catalytic activity on oxidative stress","volume":"41","author":"Limbach","year":"2007","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.envpol.2019.06.100_bib88","doi-asserted-by":"crossref","first-page":"1608","DOI":"10.1002\/smll.201202115","article-title":"Zebrafish: an in\u00a0vivo model for nano EHS studies","volume":"9","author":"Lin","year":"2013","journal-title":"Small"},{"key":"10.1016\/j.envpol.2019.06.100_bib89","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1039\/C6EE02265K","article-title":"Noble metal-metal oxide nanohybrids with tailored nanostructures for efficient solar energy conversion, photocatalysis and environmental remediation","volume":"10","author":"Liu","year":"2017","journal-title":"Energy Environ. Sci."},{"key":"10.1016\/j.envpol.2019.06.100_bib206","first-page":"676","article-title":"Toxicity of multi-walled carbon nanotubes, graphene oxide, and reduced graphene oxide to Zebrafish embryos","volume":"27","author":"Liu","year":"2014","journal-title":"Biomed. Environ. Sci."},{"key":"10.1016\/j.envpol.2019.06.100_bib90","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1016\/j.jfda.2015.02.009","article-title":"Analysis of titanium dioxide and zinc oxide nanoparticles in cosmetics","volume":"23","author":"Lu","year":"2015","journal-title":"J.\u00a0Food Drug Anal."},{"key":"10.1016\/j.envpol.2019.06.100_bib91","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.cogsc.2017.04.001","article-title":"Application of titanium dioxide nanoparticles as a photocatalyst for the removal of micropollutants such as pharmaceuticals from water","volume":"6","author":"Mahmoud","year":"2017","journal-title":"Curr. Opin. Green Sustain. Chem."},{"key":"10.1016\/j.envpol.2019.06.100_bib92","doi-asserted-by":"crossref","first-page":"12821","DOI":"10.1007\/s11356-018-1420-9","article-title":"In\u00a0vivo toxicity evaluation of pristine graphene in developing zebrafish (Danio rerio) embryos","volume":"25","author":"Manjunatha","year":"2018","journal-title":"Environ. Sci. Pollut. Res. Int."},{"key":"10.1016\/j.envpol.2019.06.100_bib93","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/j.chemosphere.2013.02.060","article-title":"Assessment of nanosilver toxicity during zebrafish (Danio rerio) development","volume":"92","author":"Massarsky","year":"2013","journal-title":"Chemosphere"},{"key":"10.1016\/j.envpol.2019.06.100_bib94","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/j.scitotenv.2014.01.077","article-title":"Acute embryonic exposure to nanosilver or silver ion does not disrupt the stress response in zebrafish (Danio rerio) larvae and adults","volume":"478","author":"Massarsky","year":"2014","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.envpol.2019.06.100_bib96","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1093\/toxsci\/kfy115","article-title":"Ancestral TCDD exposure induces multigenerational histologic and transcriptomic alterations in gonads of male zebrafish","volume":"164","author":"Meyer","year":"2018","journal-title":"Toxicol. Sci."},{"key":"10.1016\/j.envpol.2019.06.100_bib97","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/j.aquatox.2015.02.002","article-title":"Effects of titanium dioxide nanoparticles on lead bioconcentration and toxicity on thyroid endocrine system and neuronal development in zebrafish larvae","volume":"161","author":"Miao","year":"2015","journal-title":"Aquat. Toxicol."},{"key":"10.1016\/j.envpol.2019.06.100_bib98","doi-asserted-by":"crossref","first-page":"282","DOI":"10.4103\/0975-7406.72127","article-title":"Introduction to metallic nanoparticles","volume":"2","author":"Mody","year":"2010","journal-title":"J.\u00a0Pharm. BioAllied Sci."},{"key":"10.1016\/j.envpol.2019.06.100_bib99","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1387\/ijdb.062220em","article-title":"Zebrafish spata2 is expressed at early developmental stages","volume":"51","author":"Moro","year":"2017","journal-title":"Int. J. Dev. Biol."},{"key":"10.1016\/j.envpol.2019.06.100_bib100","doi-asserted-by":"crossref","first-page":"1264","DOI":"10.1007\/s10646-013-1114-5","article-title":"The toxicity of silver nanoparticles to zebrafish embryos increases through sewage treatment processes","volume":"22","author":"Muth-Kohne","year":"2013","journal-title":"Ecotoxicology"},{"key":"10.1016\/j.envpol.2019.06.100_bib102","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1016\/j.fsi.2018.03.010","article-title":"Chitosan nanoparticles: a positive immune response modulator as display in zebrafish larvae against Aeromonas hydrophila infection","volume":"76","author":"Nikapitiya","year":"2018","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.envpol.2019.06.100_bib106","series-title":"List of Manufactured Nanomaterials and List of Endpoint for Phase One of the Sponsorship Programme for the Testing of Manufactured Nanomaterials: Revision","first-page":"46","author":"OECD","year":"2010"},{"key":"10.1016\/j.envpol.2019.06.100_bib107","series-title":"OECD. OECD Guidelines for the Testing of Chemicals. Section 2: Effects on Biotic Systems Test No. 236: Applicability of the Fish Embryo Acute Toxicity (FET) Test","author":"OECD","year":"2013"},{"key":"10.1016\/j.envpol.2019.06.100_bib108","doi-asserted-by":"crossref","first-page":"295","DOI":"10.3109\/17435390.2013.778345","article-title":"Mechanistic insights into the effect of nanoparticles on zebrafish hatch","volume":"8","author":"Ong","year":"2013","journal-title":"Nanotoxicology"},{"key":"10.1016\/j.envpol.2019.06.100_bib109","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/j.cbpc.2017.03.004","article-title":"Developmental and reproductive toxicity of PVP\/PEI-coated silver nanoparticles to zebrafish","volume":"199","author":"Orbea","year":"2017","journal-title":"Comp. Biochem. Physiol. C Toxicol. Pharmacol."},{"key":"10.1016\/j.envpol.2019.06.100_bib110","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1088\/1468-6996\/9\/3\/035004","article-title":"Enhanced bioactivity of ZnO nanoparticles- na antimicrobial study","volume":"9","author":"Padmavathy","year":"2008","journal-title":"Sci. Technol. Adv. Mater."},{"key":"10.1016\/j.envpol.2019.06.100_bib112","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1016\/j.watres.2014.02.036","article-title":"Uptake of Ag and TiO2 nanoparticles by zebrafish embryos in the presence of other contaminants in the aquatic environment","volume":"55","author":"Pavagadhi","year":"2014","journal-title":"Water Res."},{"key":"10.1016\/j.envpol.2019.06.100_bib113","doi-asserted-by":"crossref","first-page":"9532","DOI":"10.1021\/acs.est.5b00997","article-title":"Adapting OECD aquatic toxicity tests for use with manufactured nanomaterials: key issues and consensus recommendations","volume":"49","author":"Petersen","year":"2015","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.envpol.2019.06.100_bib114","doi-asserted-by":"crossref","first-page":"37145","DOI":"10.1038\/srep37145","article-title":"Use of zebrafish larvae as a multi-endpoint platform to characterize the toxicity profile of silica nanoparticles","volume":"6","author":"Pham","year":"2016","journal-title":"Sci. Rep."},{"key":"10.1016\/j.envpol.2019.06.100_bib115","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/j.aquatox.2017.11.017","article-title":"Uptake, tissue distribution, and toxicity of polystyrene nanoparticles in developing zebrafish (Danio rerio)","volume":"194","author":"Pitt","year":"2018","journal-title":"Aquat. Toxicol."},{"key":"10.1016\/j.envpol.2019.06.100_bib116","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/j.aquatox.2017.06.017","article-title":"Exploring uptake and biodistribution of polystyrene (nano)particles in zebrafish embryos at different developmental stages","volume":"190","author":"Pomeren","year":"2017","journal-title":"Aquat. Toxicol."},{"key":"10.1016\/j.envpol.2019.06.100_bib117","doi-asserted-by":"crossref","first-page":"708","DOI":"10.1016\/j.ntt.2011.02.002","article-title":"Silver nanoparticles alter zebrafish development and larval behavior: distinct roles for particle size, coating and composition","volume":"33","author":"Powers","year":"2011","journal-title":"Neurotoxicol. Teratol."},{"key":"10.1016\/j.envpol.2019.06.100_bib118","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1016\/j.ntt.2010.01.009","article-title":"Silver exposure in developing zebrafish (Danio rerio): persistent effects on larval behavior and survival","volume":"32","author":"Powers","year":"2010","journal-title":"Neurotoxicol. Teratol."},{"key":"10.1016\/j.envpol.2019.06.100_bib121","first-page":"182","article-title":"Nanotechnology in groundwater remediation","volume":"2","author":"Rajan","year":"2011","journal-title":"Environ. Sci. Dev."},{"key":"10.1016\/j.envpol.2019.06.100_bib122","doi-asserted-by":"crossref","first-page":"674","DOI":"10.1016\/j.msec.2016.12.110","article-title":"Anticancer activity of biologically synthesized silver and gold nanoparticles on mouse myoblast cancer cells and their toxicity against embryonic zebrafish","volume":"73","author":"Ramachandran","year":"2017","journal-title":"Mater Sci. Eng. C Mater Biol. Appl."},{"key":"10.1016\/j.envpol.2019.06.100_bib123","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1046\/j.1365-2109.2000.00401.x","volume":"31","author":"Rawson","year":"2001","journal-title":"Aquacult. Res."},{"key":"10.1016\/j.envpol.2019.06.100_bib207","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1016\/j.marenvres.2015.06.013","article-title":"Ecotoxicological impact of engineered nanomaterials in bivalve molluscs: An overview","volume":"111","author":"Rocha","year":"2015","journal-title":"Mar. Environ. Res."},{"key":"10.1016\/j.envpol.2019.06.100_bib124","first-page":"218","article-title":"Zebrafish: from disease modeling to drug Discovery","volume":"6","author":"Rubinstein","year":"2003","journal-title":"Curr. Opin. Drug Discov. Dev"},{"key":"10.1016\/j.envpol.2019.06.100_bib125","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1186\/1477-3155-2-3","article-title":"Applications of nanoparticles in biology and medicine","volume":"2","author":"Salata","year":"2004","journal-title":"NanoBiotechnology"},{"key":"10.1016\/j.envpol.2019.06.100_bib126","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/j.ecoenv.2015.03.012","article-title":"Efficacy of the hatching event in assessing the embryo toxicity of the nano-sized TiO2 particles in zebrafish: a comparison between two different classes of hatching-derived variables","volume":"116","author":"Samaee","year":"2015","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.envpol.2019.06.100_bib127","first-page":"11","article-title":"Interaction of nanoparticles with proteins: relation to bio-reactivity of the nanoparticle","volume":"19","author":"Saptarshi","year":"2013","journal-title":"NanoBiotechnology"},{"key":"10.1016\/j.envpol.2019.06.100_bib130","doi-asserted-by":"crossref","first-page":"2077","DOI":"10.1007\/s00204-016-1734-7","article-title":"A\u00a0critical evaluation of the fish early-life stage toxicity test for engineered nanomaterials: experimental modifications and recommendations","volume":"90","author":"Shaw","year":"2016","journal-title":"Arch. Toxicol."},{"key":"10.1016\/j.envpol.2019.06.100_bib132","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1016\/j.ecoenv.2018.08.093","article-title":"Toxicity assessment of TiO2-MWCNT nanohybrid material with enhanced photocatalytic activity on Danio rerio (Zebrafish) embryos","volume":"165","author":"Silva","year":"2018","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.envpol.2019.06.100_bib133","doi-asserted-by":"crossref","first-page":"1501","DOI":"10.3389\/fmicb.2017.01501","article-title":"Application of nanotechnology in food science: perception and overview","volume":"8","author":"Singh","year":"2017","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.envpol.2019.06.100_bib134","doi-asserted-by":"crossref","first-page":"95","DOI":"10.2147\/NSA.S19419","article-title":"Titanium dioxide and zinc oxide nanoparticles in sunscreens: focus on their safety and effectiveness","volume":"4","author":"Smijs","year":"2011","journal-title":"Nanotechnol. Sci. Appl."},{"key":"10.1016\/j.envpol.2019.06.100_bib135","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1002\/etc.4055","article-title":"Applicability of the fish embryo acute toxicity (FET) test (OECD 236) in the regulatory context of registration, evaluation, authorisation, and restriction of chemicals (REACH)","volume":"37","author":"Sobanska","year":"2018","journal-title":"Environ. Toxicol. Chem."},{"key":"10.1016\/j.envpol.2019.06.100_bib137","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/j.tiv.2017.08.010","article-title":"Effects of copper oxide nanoparticles and copper ions to zebrafish (Danio rerio) cells, embryos and fry","volume":"45","author":"Thit","year":"2017","journal-title":"Toxicol. Vitro"},{"key":"10.1016\/j.envpol.2019.06.100_bib138","doi-asserted-by":"crossref","first-page":"588","DOI":"10.1016\/j.envpol.2018.10.092","article-title":"Altered Gene expression of ABC transporters, nuclear receptors and oxidative stress signaling in zebrafish embryos exposed to CdTe quantum dots","volume":"244","author":"Tian","year":"2019","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.envpol.2019.06.100_bib139","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1002\/cmdc.200600171","article-title":"Topical delivery of silver nanoparticles promotes wound healing","volume":"2","author":"Tian","year":"2007","journal-title":"ChemMedChem"},{"key":"10.1016\/j.envpol.2019.06.100_bib141","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1007\/978-1-60761-849-2_16","article-title":"Evaluation of embryotoxicity using the zebrafish model","volume":"691","author":"Truong","year":"2011","journal-title":"Methods Mol. Biol."},{"key":"10.1016\/j.envpol.2019.06.100_bib146","doi-asserted-by":"crossref","first-page":"196","DOI":"10.3109\/17435390.2013.875232","article-title":"Bioconcentration and metabolism of BDE-209 in the presence of titanium dioxide nanoparticles and impact on the thyroid endocrine system and neuronal development in zebrafish larvae","volume":"1","author":"Wang","year":"2014","journal-title":"Nanotoxicology"},{"key":"10.1016\/j.envpol.2019.06.100_bib148","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1016\/j.carbpol.2016.01.012","article-title":"Characterization and toxicology evaluation of chitosan nanoparticles on the embryonic development of zebrafish, Danio rerio","volume":"141","author":"Wang","year":"2016","journal-title":"Carbohydr. Polym."},{"key":"10.1016\/j.envpol.2019.06.100_bib150","doi-asserted-by":"crossref","first-page":"702","DOI":"10.1016\/j.toxrep.2015.03.015","article-title":"Comparative metal oxide nanoparticle toxicity using embryonic zebrafish","volume":"2","author":"Wehmas","year":"2015","journal-title":"Toxicol. Rep."},{"key":"10.1016\/j.envpol.2019.06.100_bib152","first-page":"1","article-title":"Genotoxicity and molecular response of silver nanoparticle (NP)-based hydrogel","volume":"1","author":"Xu","year":"2012","journal-title":"NanoBiotechnology"},{"key":"10.1016\/j.envpol.2019.06.100_bib153","doi-asserted-by":"crossref","first-page":"774","DOI":"10.1016\/j.bmcl.2015.12.099","article-title":"Amphiphilic nanoparticles of resveratrol-norcantharidin to enhance the toxicity in zebrafish embryo","volume":"26","author":"Yan","year":"2016","journal-title":"Bioorg. Med. Chem. Lett"},{"key":"10.1016\/j.envpol.2019.06.100_bib155","doi-asserted-by":"crossref","first-page":"644","DOI":"10.1016\/j.ijpharm.2016.10.071","article-title":"Chitosan nanoparticles and their Tween 80 modified counterparts disrupt the developmental profile of zebrafish embryos","volume":"515","author":"Yuan","year":"2016","journal-title":"Int. J. Pharm."},{"key":"10.1016\/j.envpol.2019.06.100_bib208","doi-asserted-by":"crossref","first-page":"7861","DOI":"10.1021\/acs.est.7b01922","article-title":"Molecular mechanisms of developmental toxicity induced by graphene oxide at predicted environmental concentrations","volume":"51","author":"Zhang","year":"2017","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.envpol.2019.06.100_bib158","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1016\/j.aquatox.2018.10.015","article-title":"Copper inhibits hatching of fish embryos via inducing reactive oxygen species and down-regulating Wnt signaling","volume":"205","author":"Zhang","year":"2018","journal-title":"Aquat. Toxicol."},{"key":"10.1016\/j.envpol.2019.06.100_bib159","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1016\/j.aquatox.2016.09.013","article-title":"Zinc oxide nanoparticles induce oxidative DNA damage and ROS-triggered mitochondria-mediated apoptosis in zebrafish embryos","volume":"180","author":"Zhao","year":"2016","journal-title":"Aquat. Toxicol."},{"key":"10.1016\/j.envpol.2019.06.100_bib160","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/j.aquatox.2013.03.019","article-title":"Acute ZnO nanoparticles exposure induces developmental toxicity, oxidative stress and DNA damage in embryo-larval zebrafish","volume":"136\u2013137","author":"Zhao","year":"2013","journal-title":"Aquat. Toxicol."},{"key":"10.1016\/j.envpol.2019.06.100_bib161","doi-asserted-by":"crossref","first-page":"46286","DOI":"10.1371\/journal.pone.0046286","article-title":"Toxicity assessment of iron oxide nanoparticles in zebrafish (Danio rerio) early life stages","volume":"7","author":"Zhu","year":"2012","journal-title":"PLoS One"}],"container-title":["Environmental Pollution"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0269749119317233?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0269749119317233?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,2]],"date-time":"2025-10-02T21:09:05Z","timestamp":1759439345000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0269749119317233"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,9]]},"references-count":127,"alternative-id":["S0269749119317233"],"URL":"https:\/\/doi.org\/10.1016\/j.envpol.2019.06.100","relation":{},"ISSN":["0269-7491"],"issn-type":[{"value":"0269-7491","type":"print"}],"subject":[],"published":{"date-parts":[[2019,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The zebrafish embryotoxicity test (ZET) for nanotoxicity assessment: from morphological to molecular approach","name":"articletitle","label":"Article Title"},{"value":"Environmental Pollution","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.envpol.2019.06.100","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}